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  • 2010-2014  (41)
  • 1995-1999  (4)
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  • 1
    ISSN: 1432-1238
    Keywords: Key words Growth hormone ; Insulin-like growth factor-1 ; Acute phase proteins ; C-reactive protein ; Serum amyloid A ; Interleukin-6
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Background: Human recombinant growth hormone (rhGH) has been shown to increase skeletal muscle protein synthesis and improve nitrogen balance in critically ill patients and those undergoing surgery. rhGH effects on hepatic protein turnover in critically ill patients are less clearly understood. Objective: To examine rhGH effects on hepatic acute phase protein responses and inflammatory cytokine release in patients undergoing major surgery. Design: Prospective double blind randomised trial. Setting: Tertiary referral university teaching hospital. Patients: Patients undergoing elective abdominal aortic aneurysm repair. Intervention: Patients received rhGH (Genotropin, 0.3 IU/kg per day, n = 8) or placebo (n = 10) for 6 days prior to surgery. Results: Blood levels of growth hormone (GH) and insulin-like growth factor (IGF-1) were measured following rhGH treatment and C-reactive protein (CRP), serum amyloid A (SAA) and the cytokines interleukin-6 (IL-6) and the IL-1 receptor antagonist (IL-1ra) were measured for up to 24 h following surgery. Significant increases in plasma rhGH (0.84 ± 0.3, mean (sem) versus 52 ± 20 mU/l, p 〈 0.0008) and IGF-1 levels (119 ± 13 versus 644 ± 110 ng/ml, p 〈 0.0001) were seen prior to surgery following rhGH administration. No differences in acute phase protein or cytokine levels were seen following surgery in patients receiving rhGH. Conclusions: These results indicate that pre-operative administration of rhGH does not alter acute phase protein or inflammatory cytokine release in response to major surgery.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Herzschrittmachertherapie & Elektrophysiologie 10 (1999), S. 7-15 
    ISSN: 1435-1544
    Keywords: Schlüsselwörter Dilatative Kardiomyopathie ; dekompensierte ; Herzinsuffizienz ; permanentes Pacing ; Zweikammer-Pacing ; Schrittmacher-Hämodynamik ; Key words Dilated cardiomyopathy ; congestive heart failure ; permanent pacing ; biventricular pacing ; pacing hemodynamics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Enthusiasm for permanent pacing as a therapeutic option for patients with dilated cardiomyopathy (DCM) and congestive heart failure (CHF) has waxed and waned since the early 1990‘s. The clinical results of standard dual-chamber pacing in these patients have been extraordinarily mixed, which can be attributed to small patient populations, marked heterogeneity of patients included, highly variable study designs and endpoints, and limited follow-up.  Although investigators have postulated some mechanisms for improvement, there is still a great deal to learn to be able to reliably predict which patients with DCM and/or CHF will respond to permanent pacing. Biventricular pacing is emerging as having the greatest potential for patients with congestive cardiomyopathy. Although data is somewhat limited, triple-chamber, and in some cases four-chamber pacing will be the focus of future interest.
    Notes: Zusammenfassung Die Begeisterung für das permanente Pacing als therapeutische Option bei der dilatativen Kardiomyopathie (DCM) und bei der dekompensierten Herzinsuffizienz (CHF) hat seit den frühen 90er Jahren deutlich nachgelassen. Die klinischen Ergebnisse des üblichen Zweikammer-Pacings fielen bei diesen Patienten außergewöhnlich gemischt aus. Dies kann auf kleine Patientenpopulationen, eine ausgeprägte Heterogenität der teilnehmenden Patienten, auf eine große Variabilität der Studiendesigns und Endpunkte sowie auf eine begrenzte Nachbeobachtungszeit zurückgeführt werden.  Obwohl Wissenschaftler einige Mechanismen für eine Besserung postulieren, sind viele Punkte noch offen, bis man zuverlässig voraussagen kann, welche Patienten mit DCM und/oder CHF auf ein permanentes Pacing ansprechen werden.  Es scheint so als ob das Zweikammer-Pacing das größte Potential für Patienten mit dekompensierter Herzinsuffizienz bietet. Obwohl erst limitierte Daten zur Verfügung stehen, wird in Zukunft das Dreikammer-Pacing und in manchen Fällen das Vierkammer-Pacing von Interesse sei.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Journal of radioanalytical and nuclear chemistry 201 (1995), S. 135-141 
    ISSN: 1588-2780
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Energy, Environment Protection, Nuclear Power Engineering
    Notes: Abstract Fluoride (F−) binding to humic acid has been measured as a function of pH (5–6.6). The pH dependent binding is attributed to the anion being trapped within the large structure (territorial bound) but is not bound to a particular functional group (site bound). Studying fluoride binding provides insight to cation, anion and neutral species interactions with humic acid.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Journal of radioanalytical and nuclear chemistry 193 (1995), S. 89-92 
    ISSN: 1588-2780
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Energy, Environment Protection, Nuclear Power Engineering
    Notes: Abstract A small, unmanned aerial vehicle (UAV) equipped with sensors for physical and chemical measurements of remote environments, is described. A miniature helicopter airframe is used as a platform for sensor testing and development. The sensor output is integrated with the flight control system for real-time, interactive, data acquisition and analysis. Pre-programmed flight missions will be flown with several sensors to demonstrate the cost-effective surveillance capabilities of this new technology.
    Type of Medium: Electronic Resource
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  • 5
    Publication Date: 2021-06-25
    Description: MOON (Mediterranean Operational Oceanography Network http://www.moon-oceanforecasting.eu) provides near-real-time information on oil-spill detection (ocean color and SAR) and predictions [ocean forecasts (MFS and CYCOFOS) and oil-spill predictions (MEDSLIK)]. We employ this system to study the Lebanese oil-pollution crisis in summer 2006 and thus to assist regional and local decision makers in Europe, regionally and locally. The MEDSLIK oil-spill predictions obtained using CYCOFOS high-resolution ocean fields are compared with those obtained using lower-resolution MFS hydrodynamics, and both are validated against satellite observations. The predicted beached oil distributions along the Lebanese and Syrian coasts are compared with in situ observations. The oil-spill predictions are able to simulate the northward movement of the oil spill, with the CYCOFOS predictions being in better agreement with satellite observations. Among the free MEDSLIK parameters tested in the sensitivity experiments, the drift factor appears to be the most relevant to improve the quality of the results.
    Description: Published
    Description: 140–153
    Description: JCR Journal
    Description: restricted
    Keywords: Lebanese oil-pollution event; Oil-spill modeling; Operational oceanography; Remote sensing; Levantine Basin ; 03. Hydrosphere::03.02. Hydrology::03.02.99. General or miscellaneous
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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  • 6
    Publication Date: 2020-10-15
    Description: The Mediterranean Operational Oceanography Network (MOON ) provides near-real-time information on oil spill detection and predictions that have been used during the Lebanese oil pollution crisis in summer 2006. A MOON decision support system for oil spill monitoring and prediction comprising ocean colour satellite and SAR images, ocean current forecast (MFS-Mediterranean Forecasting System and CYCOFOS-CYprus Coastal Ocean Forecasting & Observing System) and the MEDSLIK oil spill model has been developed. The oil spill predictions obtained with MEDSLIK coupled to the CYCOFOS high-resolution ocean fields are compared with the oil spill predictions obtained using the lower resolution MFS hydrodynamics and both are validated against satellite observations. The predicted beached oil quatity along the Lebanese and Syrian coasts are compared with the in-situ observations. It is found that predictions with both CYCOFOS and MFS ar capable to simulate the northward movement of the oil, with the higher resolution CYCOFOS predictions in better agreement with satellite observations. Among the free MEDSLIK oil spill parameters tested in the sensitivity experiments there are the wind corrections (wind factor and angle) and the depth of coupling between eulerian fields and wind correction. Among them the drift factor appeared the most relevant in order to improve the quality of results suggesting that operational models such as MFS and CYCOFOS still lack of enought resolution and physical process at the air-sea interface. The oil moved from Lat 33°40'N Lon 35°24.75'E northward toward Syria, which was reached in 10 days at Lat 34° 38.451'N Lon 35° 58.377'E; the oil movement is followed up to August 6 when the oil reached 35.5°N.
    Description: Not submitted
    Description: 4.6. Oceanografia operativa per la valutazione dei rischi in aree marine
    Description: JCR Journal
    Description: open
    Keywords: Lebanese oil pollution event ; oil spill modelling ; operational oceanography ; remote sensing ; Levantine Basin ; 03. Hydrosphere::03.01. General::03.01.05. Operational oceanography
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: manuscript
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  • 7
    Publication Date: 2016-12-13
    Repository Name: EPIC Alfred Wegener Institut
    Type: Article , isiRev
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  • 8
    Publication Date: 2017-04-04
    Description: MOON (Mediterranean Operational Oceanography Network http://www.moon-oceanforecasting.eu) pro- vides near-real-time information on oil-spill detection (ocean color and SAR) and predictions [ocean fore- casts (MFS and CYCOFOS) and oil-spill predictions (MEDSLIK)]. We employ this system to study the Lebanese oil-pollution crisis in summer 2006 and thus to assist regional and local decision makers in Europe, regionally and locally. The MEDSLIK oil-spill predictions obtained using CYCOFOS high-resolution ocean fields are compared with those obtained using lower-resolution MFS hydrodynamics, and both are validated against satellite observations. The predicted beached oil distributions along the Lebanese and Syrian coasts are compared with in situ observations. The oil-spill predictions are able to simulate the northward movement of the oil spill, with the CYCO- FOS predictions being in better agreement with satellite observations. Among the free MEDSLIK param- eters tested in the sensitivity experiments, the drift factor appears to be the most relevant to improve the quality of the results.
    Description: The paper was produced using the INGV MFS forecasting-sys- tem product and the OC-UCY CYCOFOS forecasting-system prod- ucts. The MODIS satellite data products were processed at the GOS-CNR-ISAC Rome laboratory using the SeaDAS software devel- oped by NASA GSFC, Greenbelt, Maryland, the HDFLook software developed by The Laboratoire d’Optique Atmosphérique, Univer- sity of Lille, France, and the MS2GT tool box developed by the Uni- versity of Colorado. Procedures for oil-spill detection were developed in the ENVI environment. Processed ENVISAT-ASAR data were made available by Telespazio and JRC. Part of this work was carried out with the support of the PRIMI project (ASI Contract No. I/094/06/0) financed by the Italian Space Agency (ASI).
    Description: In press
    Description: 4.6. Oceanografia operativa per la valutazione dei rischi in aree marine
    Description: JCR Journal
    Description: reserved
    Keywords: Lebanese oil-pollution event ; Oil-spill modeling ; Operational oceanography ; Remote sensing ; Levantine Basin ; 03. Hydrosphere::03.01. General::03.01.05. Operational oceanography
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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  • 9
    Publication Date: 2020-02-10
    Description: Approximately 1700 Pg of soil carbon (C) are stored in the northern circumpolar permafrost zone, more than twice as much C than in the atmosphere. The overall amount, rate, and form of C released to the atmosphere in a warmer world will influence the strength of the permafrost C feedback to climate change. We used a survey to quantify variability in the perception of the vulnerability of permafrost C to climate change. Experts were asked to provide quantitative estimates of permafrost change in response to four scenarios of warming. For the highest warming scenario (RCP 8.5), experts hypothesized that C release from permafrost zone soils could be 19–45 Pg C by 2040, 162–288 Pg C by 2100, and 381–616 Pg C by 2300 in CO2 equivalent using 100-year CH4 global warming potential (GWP). These values become 50 % larger using 20-year CH4 GWP, with a third to a half of expected climate forcing coming from CH4 even though CH4 was only 2.3 % of the expected C release. Experts projected that two-thirds of this release could be avoided under the lowest warming scenario (RCP 2.6). These results highlight the potential risk from permafrost thaw and serve to frame a hypothesis about the magnitude of this feedback to climate change. However, the level of emissions proposed here are unlikely to overshadow the impact of fossil fuel burning, which will continue to be the main source of C emissions and climate forcing.
    Repository Name: EPIC Alfred Wegener Institut
    Type: Article , isiRev
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  • 10
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    In:  [Poster] In: Ocean Sciences Meeting 2012, 20.-24.02.2012, Salt Lake City, USA .
    Publication Date: 2012-11-29
    Type: Conference or Workshop Item , NonPeerReviewed , info:eu-repo/semantics/conferenceObject
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