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  • Springer  (113)
  • MDPI Publishing  (2)
  • American Heart Association (AHA)
  • 2010-2014  (3)
  • 1995-1999  (81)
  • 1970-1974  (17)
  • 1955-1959  (12)
  • 1930-1934  (3)
Publikationsart
Erscheinungszeitraum
Jahr
  • 11
    ISSN: 1434-601X
    Schlagwort(e): 21.10.Re ; 21.60.Ev ; 23.20.Lv ; 27.90. + b
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Physik
    Notizen: Abstract We report on a measurement of the lifetime of the 1414 keV state in232Th by the Doppler-shift recoil-distance method. This 4+ state shows all characteristics of a nearly-harmonic two-phononγ-vibrational excitation. The result for the B(E2) value obtained from the lifetime,τ=3.2 ± 0.7 ps, is in agreement with an earlier estimate of the collectivity from Coulomb-excitation yields and supports the interpretation of the 1414 keV state as a two-phononγ-vibrational excitation.
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 12
    Digitale Medien
    Digitale Medien
    Springer
    European food research and technology 201 (1995), S. 17-19 
    ISSN: 1438-2385
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Beschreibung / Inhaltsverzeichnis: Zusammenfassung Weltweit werden jährlich etwa 200000 t des Shii-take Pilzes (Lentinus edodes) produziert. Verschiedene positive, biologische Wirkungen sind bekannt (anticarcinogene, cholesterinsenkende Wirkungen und stimulierende Wirkungen auf das Immunsystem), aber die Mineralstoff- und Aminosäuregehalte des Pilzes sind bislang nur wenig untersucht. Die Mineralstoffgehalte sind im allgemeinen niedriger als die des Kulturchampignons (Agaricus bisporus) oder des Austernseitlings (Pleurotus ostreatus). Die größten Unterschiede liegen bei den Kalium-, Phosphor-,Calcium-, Kupfer-, Strontium-, Mangan- und Zinkgehalten vor. Die Gehalte sind in Hüten höher als in den Stielen. Der Gesamtaminosäuregehalt beträgt 15,24% in den Hüten und 11,35% in den Stielen, bez. auf Trokkenmasse, und beträgt somit etwa die Hälfte des Gehaltes von Kulturchampignons. Die Phe-, Gly, His-, Arg-, Ile- und Met-Gehalte sind relativ höher als die von Champignon-Sorten.
    Notizen: Abstract World wide about 200000 tons of shii-take mushrooms (Lentinus edodes) are produced per year. Different positive biological effects are known (anticarcinogenic, anticholesterol, immunostimulating effects), but the mineral contents and amino acid composition of caps and stipes are still little investigated. The concentrations of minerals are in general lower than those in the cultivated white mushroom (Agaricus bisporus) and in the oyster mushroom (Pleurotus ostreatus). The greatest differences are found in the concentrations of potassium, phosphorus, calcium, copper, strontium, manganese and zinc. The cocentrations are higher in caps than in stipes. The total amino acid content is 15,24% in caps and 11,35% in stipes (dry matter) and thus in general half of the concentration of cultivated champignon. The amounts of Phe, Gly, His, Arg, Ile and Met are relative higher than inAgaricus fruit bodies.
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 13
    Digitale Medien
    Digitale Medien
    Springer
    European food research and technology 201 (1995), S. 524-527 
    ISSN: 1438-2385
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: Abstract The boron contents of 68 edible common macrofungi of Hungary were analysed. The average boron content of the examples was 11,74 mg/kg dry mass, this is higher than the average value of green plants of Hungary (7,4 mg/kg dry mass). Although the highest boron contents were found in the examples from woods near Budapest, the differences between the various sites are not significant. It seems that the site has not an important effect on the boron content of mushrooms. Some taxonomical groups are examples of higher, others are examples of lower boron content. The highest concentration of boron (54,3 mg/kg dry mass) was found in the speciesMarasmius wynnei which indicates a bioconcentration of four to five fold to the average boron level. Significant bioaccumulation of analysed edible species was not established, but the poisoning mushroomMycena pura has a very great (401–607 mg/kg dry mass) boron concentration. This accumulation is observed to the first time.
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 14
    ISSN: 1432-1440
    Schlagwort(e): Callus ; Osteoblast ; Collagen metabolism ; Osteocalcin ; Parathyroid hormone
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract We compared the expression of osteoblastic markers in cultured human cells isolated from fracture calluses of various histological states of development with that in cells from adult and fetal bone. Adult osteoblasts and all callus cells produced almost exclusively type I collagen, whereas fetal osteoblasts produced also considerable amounts of type III collagen in vitro. 1,25-Dihydroxyvitamin D3 induced the synthesis of osteocalcin in all bone and callus cells but to varying extents. Fetal bone cells and early-stage callus cells synthesized less than 10% the amount of osteocalcin produced by adult bone cells. Late-stage callus cells produced intermediate levels of osteocalcin. Fetal bone cells and early-stage callus cells responded to parathyroid hormone with a less pronounced increase in intracellular cAMP than did adult bone cells. Late-stage callus cells showed the best response to parathyroid hormone. The activity of alkaline phosphatase was highest in fetal bone cells. These observations show that cells isolated from fetal bone and from fracture callus tissues express a pattern of markers clearly relating them to the osteoblastic lineage. On the basis of the different patterns of osteoblastic markers expressed in vitro we conclude that functionally distinct subtypes of osteoblasts do exist in different mineralized tissues and at different developmental stages.
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 15
    Digitale Medien
    Digitale Medien
    Springer
    Journal of molecular medicine 37 (1959), S. 250-252 
    ISSN: 1432-1440
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Zusammenfassung Wie sich aus einem großen, statistisch bearbeiteten klinischen Material ergibt, sprechen hohe Basophilenwerte eindeutig gegen eine Hyperthyreose und erniedrigte Basophilenwerte eindeutig gegen ein Myxödem. Auf Grund der Beeinflussung der Basophilenzahl durch außerhalb der Schilddrüsenwirkung gelegene Faktoren sind jedoch niedere Basophilenwerte zur Stellung der Hyperthyreosendiagnose bzw. erhöhte Basophilenwerte zur Stellung der Myxödemdiagnose nur beschränkt zu gebrauchen. Die Bestimmung der Basophilenzahl scheint zur Beurteilung des Therapieerfolges brauchbar.
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 16
    Digitale Medien
    Digitale Medien
    Springer
    Journal of molecular medicine 75 (1997), S. 217-222 
    ISSN: 1432-1440
    Schlagwort(e): Key words Angiotensin II ; Human skin fibroblasts ; Hypertension ; Arteriosclerosis
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract  Angiotensin II is involved in blood pressure regulation, cell growth and angioneogenesis. The angiotensin receptors which mediate the intracellular effects of angiotensin II are expressed in numerous tissues and cell types. We studied the expression of angiotensin II receptors in cultured human skin fibroblasts derived from a skin biopsy. Angiotensin II binding characteristics were analyzed by radioligand binding assays. The DNA synthesis was assessed by [H]thymidine incorporation assays. Intracellular calcium concentrations were measured by fura-2 spectrofluorometry, and mRNA expression levels were analyzed by northern blot technology. Two distinct angiotensin receptors were detectable on human skin fibroblasts: the AT1 receptor with K d=1.0± 0.7 nmol/l and B max=17.9±0.9 fmol/mg protein, and an angiotensin(1–7) binding site with K d=26±6.6 nmol/l and B max=80.4±3.5 fmol/mg protein, as shown by competition binding assays using selective angiotensin II receptor antagonists and the heptapeptide angiotensin(1–7). The angiotensin AT1 receptor mRNA was substantially expressed in human skin fibroblasts and was subjected to homologous downregulation. In human skin fibroblasts angiotensin II caused a profound increase in intracellular calcium which was blocked by angiotensin AT1 receptor antagonists such as Exp-3174. Furthermore, both angiotensin II and angiotensin(1–7) led to increased DNA synthesis in human skin fibroblasts. In conclusion, cultured human skin fibroblasts express angiotensin AT1 receptors and a putatively new angiotensin receptor activated by angiotensin(1–7), both coupled to signaling pathways involved in DNA synthesis.
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 17
    Digitale Medien
    Digitale Medien
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 354 (1996), S. 320-326 
    ISSN: 1432-1912
    Schlagwort(e): Rat liver ; Transport of organic cations ; OCT1 ; Type I hepatic transport of cationic drugs ; 1-Methyl-4-phenylpyridinium
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract The kidneys and the liver are the principal organs for the inactivation of circulating organic cations. Recently, an organic cation transporter (OCT1) has been cloned from rat kidney. In order to answer the question whether OCT1 is involved also in hepatic uptake of organic cations, the pharmacological characteristics of organic cation transport in hepatocytes were compared to the characteristics of transiently expressed OCT1. Primary cultures of rat hepatocytes avidly accumulated the small organic cation 3H-1-methyl-4-phenylpyridinium (3H-MPP+). At equilibrium, the hepatocytes accumulated 3H-MPP+ 56-fold. Initial rates of specific 3H-MPP+ transport in hepatocytes were saturable. The half-saturating concentration was 13 μmol/l. 3H-MPP+ transport was sensitive to quinine (Ki = 0.79 μmol/l) and cyanine863 (Ki = 0.097 µmol/l). Quinine and cyanine863 are known inhibitors of type I hepatic transport of cationic drugs and of renal excretion of organic cations, respectively. To compare the functional characteristics of 3H-MPP+ transport in hepatocytes with those of OCT1, OCT1 has been heterologously expressed and characterized in a mammalian cell line (293 cells). Initial rates of 3H-MPP+ transport were saturable, the Km being 13 μmol/l. The rank order of inhibitory potencies of various inhibitors was almost identical in hepatocytes and 293 cells transiently transfected with OCT1. There was a positive correlation between the Ki's for the inhibition of 3H-MPP+ transport in isolated hepatocytes and transfected 293 cells (r = 0.85; P〈0.01; n = 8). The results indicate that OCT1 is functionally expressed not only in the kidney but also in hepatocytes where it is responsible for the transport of small organic cations which, in the past, have been classified as type I substrates.
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 18
    ISSN: 1432-1904
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Chemie und Pharmazie , Allgemeine Naturwissenschaft
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 19
    Digitale Medien
    Digitale Medien
    Springer
    Annals of hematology 2 (1956), S. 320-326 
    ISSN: 1432-0584
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 20
    Digitale Medien
    Digitale Medien
    Springer
    Applied physics 69 (1999), S. 233-237 
    ISSN: 1432-0630
    Schlagwort(e): PACS: 81.10.-h; 81.15Pq; 61.82.-d
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Maschinenbau , Physik
    Notizen: Abstract. Copper single-crystals are grown by a galvanic method, using etched ion tracks in a polymer foil as templates. The copper deposition is carried out by reversible pulse electrolysis in an ultrasonic field. The method applied for this purpose permits fabrication of stable standing cylindrical single crystals with diameters in the nanometer and micrometer range with high aspect ratio and density of 105–107 per cm2 on a large area. The experimental results obtained in this way are compared with the results obtained by direct current plating under ultrasonic treatment and sole reversible electrolysis. The effects of all these deposition processes on the structure of copper claddings are shown.
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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