In:
Clinical Nuclear Medicine, Ovid Technologies (Wolters Kluwer Health), Vol. 44, No. 5 ( 2019-5), p. 410-411
Abstract:
The novel PET probe 2-deoxy-2- 18 F-fluoro- d -sorbitol ( 18 F-FDS) has demonstrated favorable renal kinetics in animals. We aimed to elucidate its imaging properties in 2 human volunteers. 18 F-FDS was produced by a simple 1-step reduction from 18 F-FDG. On dynamic renal PET, the cortex was delineated and activity gradually transited in the parenchyma, followed by radiotracer excretion. No adverse effects were reported. Given the higher spatiotemporal resolution of PET relative to conventional scintigraphy, 18 F-FDS PET offers a more thorough evaluation of human renal kinetics. Due to its simple production from 18 F-FDG, 18 F-FDS is virtually available at any PET facility with radiochemistry infrastructure.
Type of Medium:
Online Resource
ISSN:
1536-0229
,
0363-9762
DOI:
10.1097/RLU.0000000000002494
Language:
English
Publisher:
Ovid Technologies (Wolters Kluwer Health)
Publication Date:
2019
detail.hit.zdb_id:
2045053-9
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