GLORIA

GEOMAR Library Ocean Research Information Access

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Publication Date: 2018-04-14
    Description: Author(s): Z. F. Wang, Zhao Liu, Jinlong Yang, and Feng Liu Coupling a quantum anomalous Hall (QAH) state with a superconducting state offers an attractive approach to detect the signature alluding to a topological superconducting state [Q. L. He et al. , Science 357 , 294 (2017) ], but its explanation could be clouded by disorder effects in magnetic doped QAH ... [Phys. Rev. Lett. 120, 156406] Published Fri Apr 13, 2018
    Keywords: Condensed Matter: Electronic Properties, etc.
    Print ISSN: 0031-9007
    Electronic ISSN: 1079-7114
    Topics: Physics
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 2
    Publication Date: 2016-03-01
    Description: Hyperhomocysteinemia (HHcy) is associated with liver diseases such as fatty liver and hepatic fibrosis; however, the underlying mechanism is still largely unknown. The current study aimed to explore the signaling pathway involved in HHcy-induced hepatic steatosis. C57BL/6 mice were fed a high-methionine diet (HMD) for 4 and 8 weeks to establish the HHcy mouse model. Compared to a chow diet, the HMD induced hepatic steatosis and elevated hepatic expression of CD36, a fatty acid transport protein. The increased CD36 expression was associated with activation of the aryl hydrocarbon receptor (AHR). In primary cultured hepatocytes, high levels of homocysteine (Hcy) treatment upregulated CD36 and increased subsequent lipid uptake; both were significantly attenuated by siRNA knockdown of CD36 and AHR. Chromatin immunoprecipitation assay revealed that Hcy promoted the binding of AHR to the CD36 promoter, and transient transfection assay demonstrated markedly increased activity of the AHR response element by Hcy, which was ligand-dependent. Mass spectrometry revealed significantly increased hepatic content of lipoxin A 4 (LXA 4 ), a metabolite of arachidonic acid, in HMD-fed mice. Further, over-expression of 15-oxoprostaglandin 13-reductase 1, a LXA 4 inactivation enzyme, inhibited Hcy-induced AHR activation, lipid uptake and lipid accumulation. Moreover, LXA 4 -induced upregulation of CD36 and lipid uptake was inhibited by AHR siRNA in vitro in hepatocytes. Finally, treatment with an AHR antagonist reversed the HHcy-induced lipid accumulation by inhibiting the AHR-CD36 pathway in mice. In conclusion, our results strongly suggest that HHcy activated the AHR-CD36 pathway by increasing hepatic LXA 4 content, which resulted in hepatic steatosis. This article is protected by copyright. All rights reserved.
    Print ISSN: 0270-9139
    Electronic ISSN: 1527-3350
    Topics: Medicine
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 3
    Publication Date: 2015-12-05
    Description: The Journal of Organic Chemistry DOI: 10.1021/acs.joc.5b02238
    Print ISSN: 0022-3263
    Electronic ISSN: 1520-6904
    Topics: Chemistry and Pharmacology
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 4
    Publication Date: 2017-03-08
    Description: Similar to loess-paleosol sequences in northwestern China, terrestrial sedimentary sequences (red soils) in southern China also provide sensitive Quaternary records of subtropical/tropical paleoclimate and paleoenvironment. Compared with red clay sequences originated from eolian dust, red soils derived from bedrock have received little attention. In this study, a long core of red soil derived from weathered basalt in northern Hainan Island, China, was systematically investigated using detailed magnetic measurements and rare earth element analyses. The results show that an extremely strong magnetic zone with a maximum magnetic susceptibility (〉10 × 10 –5 m 3 kg –1 ) is interbedded in the middle of the core profile. This layer contains a significant amount of superparamagnetic magnetite/maghemite particles that primarily originated from volcanic ash, with secondary contributions from pedogenesis. The former has an average grain size of ~19 nm with a normal distribution of volume, and the latter has a much wider grain size distribution. The presence of volcanic ash within the red soil indicates that these Quaternary basalts were not formed by continuous volcanic eruptions. Moreover, the magnetic enhancement patterns differ between the upper and lower zones. The upper zone is more magnetically enhanced and experienced higher precipitation and temperature than the lower zone. Discrimination of superparamagnetic particles originating from pedogenic processes and volcanic ash thus provides a sound theoretical base for accurate interpretation of magnetism in red soils in this region.
    Print ISSN: 0148-0227
    Topics: Geosciences , Physics
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 5
    Publication Date: 2017-01-26
    Description: Influential nodes are rare in social networks, but their influence can quickly spread to most nodes in the network. Identifying influential nodes allows us to better control epidemic outbreaks, accelerate information propagation, conduct successful e-commerce advertisements, and so on. Classic methods for ranking influential nodes have limitations because they ignore the impact of the topology of neighbor nodes on a node. To solve this problem, we propose a novel measure based on local centrality with a coefficient. The proposed algorithm considers both the topological connections among neighbors and the number of neighbor nodes. First, we compute the number of neighbor nodes to identify nodes in cluster centers and those that exhibit the “bridge” property. Then, we construct a decreasing function for the local clustering coefficient of nodes, called the coefficient of local centrality, which ranks nodes that have the same number of four-layer neighbors. We perform experiments to measure node influence on both real and computer-generated networks using six measures: Degree Centrality, Betweenness Centrality, Closeness Centrality, K-Shell, Semi-local Centrality and our measure. The results show that the rankings obtained by the proposed measure are most similar to those of the benchmark Susceptible-Infected-Recovered model, thus verifying that our measure more accurately reflects the influence of nodes than do the other measures. Further, among the six tested measures, our method distinguishes node influence most effectively.
    Electronic ISSN: 2220-9964
    Topics: Architecture, Civil Engineering, Surveying , Geosciences
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...