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  • 1
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    University of Wyoming, Department of Renewable Resources | Laramie, Wyoming
    Publication Date: 2021-05-19
    Description: Institutional, environmental, and economic factors are affecting water quality and quantity within the River Njoro, a major tributary to Lake Nakuru. Between 1979 and 1999, the population within the Njoro watershed greatly increased, from 270,912 people to 413,698 spurring large-scale land use change and increased pressure on watershed resources. In 2003, the USAID funded, Sustainable Management of Rural Watersheds Project (SUMAWA) implemented participatory rural appraisals in the Njoro watershed to identify water use and other resource concerns within the area. Local residents identified two main concerns: 1) lower water quality and associated increases in water borne diseases and 2) reduced access to water and lack of improved water supplies related in part to reduced water quantity. Preliminary results suggest that the hydrologic response within the watershed has been altered to favor increased annual runoff with higher intensity and longer dry spells (Baldyga, 2005). Forest conversion to small-scale agriculture reduces canopy cover, thus exposing soils. If rainfall rates exceed infiltration rates, water once intercepted by the forest canopy contributes to flow flashiness and altered flow regimes. In turn, this may affect the recharge timing of Lake Nakuru.
    Description: Published
    Keywords: GIS ; Water quality ; Fishery institutions ; Water use ; Watersheds ; Lake basins ; Environmental impact
    Repository Name: AquaDocs
    Type: Report , Not Known
    Format: 9pp.
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  • 2
    Publication Date: 2018-06-15
    Description: Cell differentiation is directed by signals driving progenitors into specialized cell types. This process can involve collective decision-making, when differentiating cells determine their lineage choice by interacting with each other. We used live-cell imaging in microwell arrays to study collective processes affecting differentiation of naïve CD4 + T cells into memory precursors. We found that differentiation of precursor memory T cells sharply increases above a threshold number of locally interacting cells. These homotypic interactions involve the cytokines interleukin-2 (IL-2) and IL-6, which affect memory differentiation orthogonal to their effect on proliferation and survival. Mathematical modeling suggests that the differentiation rate is continuously modulated by the instantaneous number of locally interacting cells. This cellular collectivity can prioritize allocation of immune memory to stronger responses.
    Keywords: Immunology, Online Only
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Geosciences , Computer Science , Medicine , Natural Sciences in General , Physics
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