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  • Wiley  (16)
  • 2015-2019  (16)
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  • Wiley  (16)
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  • 2015-2019  (16)
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  • 1
    Online Resource
    Online Resource
    Chronic pain induces nociceptive neurogenesis in dorsal root ganglia from Sox2‐positive satellite cells
    Wiley ; 2019
    In:  Glia Vol. 67, No. 6 ( 2019-06), p. 1062-1075
    Details
    In: Glia, Wiley, Vol. 67, No. 6 ( 2019-06), p. 1062-1075
    Abstract: Chronic pain is one of the most prevalent chronic diseases in the world. The plastic changes of sensory neurons in dorsal root ganglia (DRG) have been extensively studied as the underlying periphery mechanism. Recent studies revealed that satellite cells, the major glial cells in DRG, also played important roles in the development/modulation of chronic pain. Whether DRG satellite glial cells generate new neurons as their counterparts in enteric nerve ganglia and carotid body do under pathological conditions remains poorly investigated. Here, we report that chronic pain induces proliferation and upregulation of progenitor markers in the sex‐determining region Y‐box 2 (Sox2)‐ and platelet‐derived growth factor receptor alpha (PDGFRα)‐positive satellite glial cells. BrdU incorporation assay revealed the generation of IB4‐ and CGRP‐positive neurons, but not NF200‐positive neurons in DRG ipsilateral to injury. Genetic fate tracings showed that PDGFRα‐positive cells did not generate neurons, whereas Sox2‐positive cells produced both IB4‐ and CGRP‐positive neurons. Interestingly, glial fibrillary acidic protein‐positive cells, a subpopulation of Sox2‐positive satellites, only gave birth to IB4‐positive neurons. Local persistent delivery of tetrodotoxin to the sciatic nerve trunk significantly reduced the pain‐induced neurogenesis. Furthermore, patch‐clamp studies demonstrated that these glia‐derived new neurons could fire action potentials and respond to capsaicin. Taken together, our data demonstrated a chronic pain‐induced nociceptive neurogenesis in DRG from Sox2‐positive satellite cells, indicating a possible contribution of DRG neurogenesis to the pathology of chronic pain.
    Type of Medium: Online Resource
    ISSN: 0894-1491 , 1098-1136
    URL: Issue
    URL: Article
    DOI: 10.1002/glia.v67.6
    DOI: 10.1002/glia.23588
    Language: English
    Publisher: Wiley
    Publication Date: 2019
    detail.hit.zdb_id: 1474828-9
    SSG: 12
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  • 2
    Online Resource
    Online Resource
    The method of fundamental solution for 3‐D wave scattering in a fluid‐saturated poroelastic infinite domain
    Wiley ; 2018
    In:  International Journal for Numerical and Analytical Methods in Geomechanics Vol. 42, No. 15 ( 2018-10-25), p. 1866-1889
    Details
    In: International Journal for Numerical and Analytical Methods in Geomechanics, Wiley, Vol. 42, No. 15 ( 2018-10-25), p. 1866-1889
    Abstract: By using a complete set of poroelastodynamic spherical wave potentials (SWPs) representing a fast compressional wave P I , a slow compressional wave P II , and a shear wave S with 3 vectorial potentials (not all are independent), a solution scheme based on the method of fundamental solution (MFS) is devised to solve 3‐D wave scattering and dynamic stress concentration problems due to inhomogeneous inclusions and cavities embedded in an infinite poroelastic domain. The method is verified by comparing the result with the elastic analytical solution, which is a degenerated case, as well as with poroelastic solution obtained using other numerical methods. The accuracy and stability of the SWP‐MFS are also demonstrated. The displacement, hoop stress, and fluid pore pressure around spherical cavity and poroelastic inclusion with permeable and impermeable boundary are investigated for incident plane P I and SV waves. The scattering characteristics are examined for a range of material properties, such as porosity and shear modulus contrast, over a range of frequency. Compared with other boundary‐based numerical strategy, such as the boundary element method and the indirect boundary integral equation method, the current SWP‐MFS is a meshless method that does not need elements to approximate the geometry and is free from the treatment of singularities. The SWP‐MFS is a highly accurate and efficient solution methodology for wave scattering problems of arbitrary geometry, particularly when a part of the domain extends to infinity.
    Type of Medium: Online Resource
    ISSN: 0363-9061 , 1096-9853
    URL: Issue
    URL: Article
    DOI: 10.1002/nag.v42.15
    DOI: 10.1002/nag.2836
    Language: English
    Publisher: Wiley
    Publication Date: 2018
    detail.hit.zdb_id: 1494703-1
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  • 3
    Online Resource
    Online Resource
    Heterojunctions: One‐Dimensional Densely Aligned Perovskite‐Decorated Semiconductor Heterojunctions with Enhanced Photocatalytic Activity (Small 12/2015)
    Wiley ; 2015
    In:  Small Vol. 11, No. 12 ( 2015-03), p. 1435-1435
    Details
    In: Small, Wiley, Vol. 11, No. 12 ( 2015-03), p. 1435-1435
    Type of Medium: Online Resource
    ISSN: 1613-6810 , 1613-6829
    URL: Issue
    URL: Article
    DOI: 10.1002/smll.v11.12
    DOI: 10.1002/smll.201570070
    Language: English
    Publisher: Wiley
    Publication Date: 2015
    detail.hit.zdb_id: 2168935-0
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  • 4
    Online Resource
    Online Resource
    Mechanical, electrical, and thermal properties of highly filled bamboo charcoal/ultra‐high molecular weight polyethylene composites
    Wiley ; 2018
    In:  Polymer Composites Vol. 39, No. S3 ( 2018-06)
    Details
    In: Polymer Composites, Wiley, Vol. 39, No. S3 ( 2018-06)
    Abstract: Highly filled bamboo charcoal (BC)/ultra‐high molecular weight polyethylene (UHMWPE) composites were prepared using extrusion and hot‐compression molding methods. The addition of BC remarkably improved the tensile properties of UHMWPE composites. When the BC content reached 70 wt%, the tensile strength and Young's modulus rose from 28.0 and 326.6 MPa for the neat UHMWPE to 128.9 and 2,027.7 MPa, increasing by 360 and 520%, respectively. The incorporation of BC also significantly improved the creep resistance, especially at high temperature. The creep strains of the composites with 60, 70 and 80 wt% were reduced by 70.1, 78.3, and 85.2% compared to the neat UHMWPE at 80°C, respectively. To understand the mechanism, the Burger's model was employed to illustrate the influence of BC on the creep performance of the polymer composites. The addition of BC also increased the electrical conductivity of the composites: the composite with 80 wt% BC had a conductivity of 0.53 S/cm. Moreover, the thermal stability of BC/UHMWPE composites improved apparently with the increased charcoal loading. POLYM. COMPOS., 39:E1858–E1866, 2018. © 2018 Society of Plastics Engineers
    Type of Medium: Online Resource
    ISSN: 0272-8397 , 1548-0569
    URL: Issue
    URL: Article
    DOI: 10.1002/pc.v39.S3
    DOI: 10.1002/pc.24839
    Language: English
    Publisher: Wiley
    Publication Date: 2018
    detail.hit.zdb_id: 1475935-4
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  • 5
    Online Resource
    Online Resource
    Viral pathogens among elderly people with acute respiratory infections in Shanghai, China: Preliminary results from a laboratory‐based surveillance, 2012‐2015
    Wiley ; 2017
    In:  Journal of Medical Virology Vol. 89, No. 10 ( 2017-10), p. 1700-1706
    Details
    In: Journal of Medical Virology, Wiley, Vol. 89, No. 10 ( 2017-10), p. 1700-1706
    Abstract: Acute respiratory infections (ARIs), with viral pathogens as the major contributors, are the most common illnesses worldwide, and increase the morbidity and mortality among the elderly population. The clinical and pathological features of elderly people with ARIs need to be identified for disease intervention. From January 1, 2012 through December 31, 2015, respiratory specimens from patients above 60 years old with ARIs were collected from the outpatient and inpatient settings of six sentinel hospitals in Pudong New Area. Each specimen was tested via multiplex polymerase chain reaction (PCR) for eight target viral etiologies including influenza, human rhinovirus (HRV), human para‐influenza virus (PIV), adenovirus (ADV), respiratory syncytial virus (RSV), human metapneumovirus (hMPV), human coronavirus (hCoVs), and human bocavirus (hBoV). A total of 967 elderly patients with ARIs were enrolled, including 589 (60.91%) males, and the median age was 73 years old. 306 (31.64%) patients were tested positive for any one of the eight viruses, including 276 single infections and 30 co‐infections. Influenza was the predominant virus (14.17%, 137/967), detected from 21.35% (76/356) of the outpatients and 9.98% (61/611) of the inpatients. Influenza infections presented two annual seasonal peaks during winter and summer. Compared with non‐influenza patients, those with influenza were more likely to have fever, cough, sore throat, and fatigue. This study identified influenza as the leading viral pathogen among elderly with ARIs, and two seasonal epidemic peaks were observed in Shanghai. An influenza vaccination strategy needs to be advocated for the elderly population.
    Type of Medium: Online Resource
    ISSN: 0146-6615 , 1096-9071
    URL: Issue
    URL: Article
    DOI: 10.1002/jmv.v89.10
    DOI: 10.1002/jmv.24751
    RVK:
    XA 10000
    Language: English
    Publisher: Wiley
    Publication Date: 2017
    detail.hit.zdb_id: 752392-0
    detail.hit.zdb_id: 1475090-9
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  • 6
    Online Resource
    Online Resource
    An Aza resveratrol–chalcone derivative 6b protects mice against diabetic cardiomyopathy by alleviating inflammation and oxidative stress
    Wiley ; 2018
    In:  Journal of Cellular and Molecular Medicine Vol. 22, No. 3 ( 2018-03), p. 1931-1943
    Details
    In: Journal of Cellular and Molecular Medicine, Wiley, Vol. 22, No. 3 ( 2018-03), p. 1931-1943
    Abstract: Inflammation and oxidative stress play a crucial role in the development of diabetic cardiomyopathy (DCM). We previously had synthesized an Aza resveratrol–chalcone derivative 6b, of which effectively suppressing lipopolysaccharide (LPS)‐induced inflammatory response in macrophages. This study aimed to investigate the potential protective effect of 6b on DCM and underlying mechanism. In H9c2 myocardial cells, 6b potently decreased high glucose (HG)‐induced cell fibrosis, hypertrophy and apoptosis, alleviating inflammatory response and oxidant stress. In STZ‐induced type 1 diabetic mice (STZ‐DM1), orally administration with 6b for 16 weeks significantly attenuated cardiac hypertrophy, apoptosis and fibrosis. The expression of inflammatory cytokines and oxidative stress biomarkers was also suppressed by 6b distinctly, without affecting blood glucose and body weight. The anti‐inflammatory and antioxidative activities of 6b were mechanistic associated with nuclear factor‐kappa B (NF‐κB) nucleus entry blockage and Nrf2 activation both in vitro and in vivo . The results indicated that 6b can be a promising cardioprotective agent in treatment of DCM via inhibiting inflammation and alleviating oxidative stress. This study also validated the important role of NF‐κB and Nrf2 taken in the pathogenesis of DCM, which could be therapeutic targets for diabetic comorbidities.
    Type of Medium: Online Resource
    ISSN: 1582-1838 , 1582-4934
    URL: Issue
    URL: Article
    DOI: 10.1111/jcmm.2018.22.issue-3
    DOI: 10.1111/jcmm.13477
    Language: English
    Publisher: Wiley
    Publication Date: 2018
    detail.hit.zdb_id: 2076114-4
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  • 7
    Online Resource
    Online Resource
    One‐Dimensional Densely Aligned Perovskite‐Decorated Semiconductor Heterojunctions with Enhanced Photocatalytic Activity
    Wiley ; 2015
    In:  Small Vol. 11, No. 12 ( 2015-03), p. 1436-1442
    Details
    In: Small, Wiley, Vol. 11, No. 12 ( 2015-03), p. 1436-1442
    Abstract: By using one‐dimensional rutile TiO 2 nanorod arrays as the structure‐directing scaffold as well as the TiO 2 source to two consecutive hydrothermal reactions, densely aligned SrTiO 3 ‐modified rutile TiO 2 heterojunction photocatalysts are crafted for the first time. The first hydrothermal processing yielded nanostructured rutile TiO 2 with the hollow openings on the top of nanorods (i.e., partially etched rutile TiO 2 nanorod arrays; denoted PE‐TNRAs). The subsequent second hydrothermal treatment in the presence of Sr 2+ transforms the surface of partially etched rutile TiO 2 nanorods into SrTiO 3 nanoparticles via the concurrent dissolution of TiO 2 and precipitation of SrTiO 3 while retaining the cylindrical shape (i.e., forming SrTiO 3 ‐decorated rutile TiO 2 composite nanorods; denoted STO‐TNRAs). The structural and composition characterizations substantiate the success in achieving STO‐TNRA nanostructures. In comparison to PE‐TNRAs, STO‐TNRA photocatalysts exhibit higher photocurrents and larger photocatalytic degradation rates of methylene blue (3.21 times over PE‐TNRAs) under UV light illumination as a direct consequence of improved charge carrier mobility and enhanced electron/hole separation. Such 1D perovskite‐decorated semiconductor nanoarrays are very attractive for optoelectronic applications in photovoltaics, photocatalytic hydrogen production, among other areas.
    Type of Medium: Online Resource
    ISSN: 1613-6810 , 1613-6829
    URL: Issue
    URL: Article
    DOI: 10.1002/smll.v11.12
    DOI: 10.1002/smll.201402692
    Language: English
    Publisher: Wiley
    Publication Date: 2015
    detail.hit.zdb_id: 2168935-0
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  • 8
    Online Resource
    Online Resource
    The development of stress sensitivity and its contribution to word reading in school‐aged children
    Wiley ; 2018
    In:  Journal of Research in Reading Vol. 41, No. 2 ( 2018-05), p. 259-277
    Details
    In: Journal of Research in Reading, Wiley, Vol. 41, No. 2 ( 2018-05), p. 259-277
    Abstract: This study examined the development of stress sensitivity and its relationship with word reading. Previous research has rarely measured phoneme and stress sensitivity in the same task, making a direct comparison of the contribution between the two in reading development difficult. Methods Participants were native English‐speaking adults and children at ages of 6, 8, and 10 years ( N  = 24, 22, 22, and 24, respectively). A lexical decision task was used to measure both stress and phoneme sensitivity. Oral vocabulary, phoneme awareness, and word reading were assessed. Results Stress sensitivity accounted for unique variance in reading over and above vocabulary and phoneme awareness in 6‐year‐olds. Both adults and children had better phoneme sensitivity than stress sensitivity. Conclusions These findings highlight the unique contribution of stress sensitivity in reading development. The current study made a novel contribution to studying the relationship between prosody and literacy by utilising a task that is able to assess children's stress and phoneme sensitivity simultaneously. What is already known about this topic Prosody plays an important role in literacy acquisition across a variety of languages with word stress. Phoneme awareness as measured by the phoneme deletion task is one of the strongest predictors of reading development in English. Stress sensitivity may contribute to reading via vocabulary development, rime awareness, phoneme awareness, and morphological awareness. What this paper adds Stress sensitivity made a unique contribution to word reading over and above oral vocabulary and phoneme awareness for 6‐year‐old children. Both stress and phoneme sensitivity was measured within the same task using the same set of materials. Both children and adults showed better phoneme sensitivity compared to stress sensitivity. Implications for theory, policy, or practice Models delineating the relationship between prosody and literacy should consider unique variance explained by stress sensitivity in reading development. Children learning to read in English may need longer literacy exposure to develop better stress sensitivity because of the lack of regularity in English stress. Stress sensitivity may contribute to word reading given that it may help children understand stress assignment and learn unfamiliar stress representation as well as orthographic stress regularities.
    Type of Medium: Online Resource
    ISSN: 0141-0423 , 1467-9817
    URL: Issue
    URL: Article
    DOI: 10.1111/jrir.v41.2
    DOI: 10.1111/1467-9817.12094
    Language: English
    Publisher: Wiley
    Publication Date: 2018
    detail.hit.zdb_id: 2028937-6
    SSG: 7,11
    SSG: 5,3
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  • 9
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    Online Resource
    Ecology and phylogenetic affinity of the early Cambrian tubular microfossil Megathrix longus
    Wiley ; 2016
    In:  Palaeontology Vol. 59, No. 1 ( 2016-01), p. 13-28
    Details
    In: Palaeontology, Wiley, Vol. 59, No. 1 ( 2016-01), p. 13-28
    Abstract: Abundant, exquisitely preserved specimens of the enigmatic tubular microfossil Megathrix longus are reported from the early Cambrian Yanjiahe Formation in the Yangtze Gorges area. Studies of their morphology and taphonomy reveal that the inner cross‐wall of Megathrix longus is topographically flat, the trichome terminus is blunt and closed, and incomplete cross‐walls are regularly intercalated between complete ones. The deformation of trichomes, as well as the corrugation of their cross‐walls, are postmortem features caused by compaction, rather than biological features as previously interpreted. Statistical analysis indicates that chamber division is accomplished by the closure of incomplete cross‐walls. This process, which contributed to trichome growth, is extremely similar to that of modern Oscillatoriaceae. Trichome fragmentation was also observed in a series of specimens, which closely resembles that of cyanobacteria, particularly the Oscillatoriaceae. The termini of Megathrix longus suggest that it was planktonic. In general, Megathrix longus bears a close affinity to the extant Oscillatoriaceae (Cyanophyta).
    Type of Medium: Online Resource
    ISSN: 0031-0239 , 1475-4983
    URL: Issue
    URL: Article
    DOI: 10.1111/pala.2016.59.issue-1
    DOI: 10.1111/pala.12201
    Language: English
    Publisher: Wiley
    Publication Date: 2016
    detail.hit.zdb_id: 2034710-8
    SSG: 13
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  • 10
    Online Resource
    Online Resource
    An Exceptionally Facile Synthesis of Highly Efficient Oxygen Evolution Electrodes for Zinc‐Oxygen Batteries
    Wiley ; 2017
    In:  ChemElectroChem Vol. 4, No. 9 ( 2017-09), p. 2190-2195
    Details
    In: ChemElectroChem, Wiley, Vol. 4, No. 9 ( 2017-09), p. 2190-2195
    Abstract: Zinc‐oxygen batteries are promising candidates for electrical vehicles and electric grid energy storage due to their low cost, high safety levels, and low environmental impact. The oxygen evolution reaction (OER) and oxygen reduction reaction (ORR) represent the most significant processes in zinc‐oxygen batteries. The development of nonprecious metal catalysts for OER with satisfactory performances and low cost (especially prepared by a straightforward synthesis route), still poses a significant challenge. Herein, we report an exceptionally facile and easily scalable method to produce NiFe layered double hydroxide (LDH) coated nickel foam by immersing nickel foams into aqueous solutions containing NiCl 2 and FeCl 2 and keeping them standing for a certain period of time. Without any other complicated technique or organic reagent, microflower‐shaped NiFe LDHs can be obtained. The resulting electrode shows excellent OER performance with a low overpotential of 210 mV at a 10 mA cm −2 constant current polarization and stable operation for more than 100 charge‐discharge cycles in zinc‐oxygen batteries.
    Type of Medium: Online Resource
    ISSN: 2196-0216 , 2196-0216
    URL: Issue
    URL: Article
    DOI: 10.1002/celc.v4.9
    DOI: 10.1002/celc.201700477
    Language: English
    Publisher: Wiley
    Publication Date: 2017
    detail.hit.zdb_id: 2724978-5
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