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  • SAGE Publications  (138)
  • 2015-2019  (138)
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  • SAGE Publications  (138)
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  • 2015-2019  (138)
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  • 1
    In: Applied Spectroscopy, SAGE Publications, Vol. 70, No. 3 ( 2016-03), p. 505-519
    Abstract: An analysis of binary mixtures of hydroxyl compound by Attenuated Total Reflection Fourier transform infrared spectroscopy (ATR FT-IR) and classical least squares (CLS) yield large model error due to the presence of unmodeled components such as H-bonded components. To accommodate these spectral variations, polynomial-based least squares (LSP) and polynomial-based total least squares (TLSP) are proposed to capture the nonlinear absorbance-concentration relationship. LSP is based on assuming that only absorbance noise exists; while TLSP takes both absorbance noise and concentration noise into consideration. In addition, based on different solving strategy, two optimization algorithms (limited-memory Broyden–Fletcher–Goldfarb–Shanno (LBFGS) algorithm and Levenberg–Marquardt (LM) algorithm) are combined with TLSP and then two different TLSP versions (termed as TLSP-LBFGS and TLSP-LM) are formed. The optimum order of each nonlinear model is determined by cross-validation. Comparison and analyses of the four models are made from two aspects: absorbance prediction and concentration prediction. The results for water-ethanol solution and ethanol-ethyl lactate solution show that LSP, TLSP-LBFGS, and TLSP-LM can, for both absorbance prediction and concentration prediction, obtain smaller root mean square error of prediction than CLS. Additionally, they can also greatly enhance the accuracy of estimated pure component spectra. However, from the view of concentration prediction, the Wilcoxon signed rank test shows that there is no statistically significant difference between each nonlinear model and CLS.
    Type of Medium: Online Resource
    ISSN: 0003-7028 , 1943-3530
    RVK:
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2016
    detail.hit.zdb_id: 1474251-2
    SSG: 11
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  • 2
    In: Angiology, SAGE Publications, Vol. 66, No. 9 ( 2015-10), p. 845-855
    Abstract: Our aim was to compare the efficacy and safety of bivalirudin (Biv) versus heparin (Hep) with or without similar usage rate of glycoprotein IIb/IIIa inhibitors (GPIs) during percutaneous coronary intervention (PCI). The PubMed and EMbase were searched. Randomized trials comparing Biv versus Hep were eligible for inclusion. With imbalanced GPI use, Biv had significantly lower major bleeding (pooled risk ratio [RR], 0.67; 95% confidence interval [CI] , 0.54-0.83) without difference in mortality (pooled RR, 0.95; 95% CI, 0.80-1.14). With comparable GPI use, no significant difference was observed in major bleeding (pooled RR, 0.95; 95% CI, 0.82-1.10) and mortality (pooled RR, 1.13; 95% CI, 0.85-1.50). With no GPI use, Biv was associated with numerically higher mortality (pooled RR, 1.17; 95% CI, 0.83-1.65) without significant difference in major bleeding (pooled RR, 0.81; 95% CI, 0.64-1.02). In conclusion, when comparing different anticoagulants during PCI, the effect of GPIs should not be underestimated. Heparin as such was found noninferior to Biv.
    Type of Medium: Online Resource
    ISSN: 0003-3197 , 1940-1574
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2015
    detail.hit.zdb_id: 2065911-8
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  • 3
    In: Acupuncture in Medicine, SAGE Publications, Vol. 35, No. 5 ( 2017-10), p. 332-338
    Abstract: The aim of this multicentre randomised controlled trial was to investigate the contribution of de qi to the immediate analgesic effect of acupuncture in patients with primary dysmenorrhoea and the specific traditional Chinese medicine diagnosis cold and dampness stagnation. Method Eighty-eight patients with primary dysmenorrhoea and cold and dampness stagnation were randomly assigned to de qi (n=43) or no de qi (n=45) groups and underwent 30 min of SP6 acupuncture. The de qi group received deep needling at SP6 with manipulation using thick needles; the no de qi group received shallow needling with no manipulation using thin needles. In both groups the pain scores and actual de qi sensation were evaluated using a visual analogue scale for pain (VAS-P) and the acupuncture de qi clinical assessment scale (ADCAS), respectively. Results Both groups showed reductions in VAS-P, with no signficant differences between groups. ADCAS scores showed 43/43 and 25/45 patients in de qi and no de qi groups, respectively, actually experienced de qi sensation. Independent of original group allocation, VAS-P reductions associated with actual de qi (n=68) were greater than those without (28.4±18.19 mm vs 14.6±12.28 mm, p=0.008). Conclusions This study showed no significant difference in VAS-P scores in patients with primary dysmenorrhoea and cold and dampness stagnation immediately after SP6 acupuncture designed to induce or avoid de qi sensation. Both treatments significantly reduced VAS-P relative to baseline. Irrespective of group allocation, patients experiencing actual de qi sensation demonstrated larger reductions in pain score relative to those without, suggesting greater analgesic effects. Trial registration number Chinese Clinical Trial Registry (ChiCTR-TRC-13003086); Results.
    Type of Medium: Online Resource
    ISSN: 0964-5284 , 1759-9873
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2017
    detail.hit.zdb_id: 2126127-1
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  • 4
    Online Resource
    Online Resource
    SAGE Publications ; 2019
    In:  Acupuncture in Medicine Vol. 37, No. 1 ( 2019-02), p. 47-54
    In: Acupuncture in Medicine, SAGE Publications, Vol. 37, No. 1 ( 2019-02), p. 47-54
    Abstract: Acupuncture has been recommended as an alternative therapy for migraine. Emerging evidence suggests that the 5-HT 7 receptor (5-HT 7 R) plays a significant facilitatory role in descending modulation in migraine pathophysiology, and that activation of 5-HT 7 R in the descending pathway is involved in migraine central sensitisation. Objective: To investigate the ability of electroacupuncture (EA) to ameliorate central sensitisation via modulation of 5-HT 7 R in the descending pain pathways using a rat model of migraine induced by repetitive dural electrical stimulation (DES). Design: 64 male Sprague-Dawley rats were randomly divided into four groups: Normal group; DES group (receiving dural electrical stimulation only); DES+GB20 group (DES model group treated with EA at GB20); and DES+Sham group (DES model group treated with EA at a non-traditional (sham) acupuncture point). The presence of cutaneous allodynia was determined by measuring facial and hind-paw withdrawal latencies to electronic von-Frey. The expression of 5-HT 7 R in the descending pathways (periaqueductal grey, raphe magnus nucleus, and trigeminal nucleus caudalis) was assessed using immunofluorescence and Western blotting. Results: Facial and hind-paw withdrawal thresholds were significantly increased in the DES+GB20 group compared with the untreated DES group. The expression of 5-HT 7 R was significantly decreased in the DES+GB20 group compared with the DES group (one-way analysis of variance (ANOVA), P 〈 0.05). No significant differences in behaviour or expression were found between the rats in the DES+Sham group and the untreated DES group (one-way ANOVA, P 〉 0.05). Conclusion: EA at GB20 may ameliorate central sensitisation in migraine by inhibiting the activation of 5-HT 7 receptors in the descending pain pathway in a rat model of migraine.
    Type of Medium: Online Resource
    ISSN: 0964-5284 , 1759-9873
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2126127-1
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  • 5
    In: Cell Transplantation, SAGE Publications, Vol. 25, No. 2 ( 2016-02), p. 365-376
    Abstract: As angiogenesis and vasculogenesis involve the complex network structures of various types of cells, extracellular matrix components, and cytokines, it is still difficult to exactly mimic the microenvironment of vascularization in vivo. In our study, we constructed a complex containing highly proliferative fibroblasts that can secrete extracellular matrix components and growth factors to chemotaxize endothelial progenitor cells (EPCs) in an attempt to create an ideal microenvironment for quick vascularization. Amniotic membrane microparticles (mAM) rich in type IV collagen (COL IV) and laminin (LN) were prepared, and human dermal fibroblasts (HDF) were infected with lentivirus (LV) of overexpression of SDF-1α to construct SDF-1α ov HDF. Using the rotary cell culture system (RCCS), mAM was loaded with HDF or SDF-1α ov HDF to construct HDF-mAM and SDF-1α ov HDF-mAM complexes. The complexes were able to secrete various types of active peptides (IL-6, IL-8, TGF-β, and bFGF) during in vitro culture. In addition, SDF-1α ov HDF-mAM complex highly expressed SDF-1α. Transwell assay showed SDF-1α ov HDF-mAM complex had an apparent chemotactic effect on EPCs. Transplantation of complexes onto full-thickness skin defects of C57BL mice further demonstrated that SDF-1α expression and the number of peripheral EPCs at days 3, 5, and 7 in the SDF-1α ov HDF-mAM group were significantly higher than that in other groups ( p 〈 0.01). The local microvascular density at day 10 of transplantation showed that the microvascular density in the SDF-1α ov HDF-mAM group was significantly higher than that in HDF-mAM group ( p 〈 0.01). In conclusion, HDF-mAM had a strong proliferative activity and could be used to create a sound microenvironment for quick vascularization by secreting multiple cytokines and extracellular matrix components. Overexpression of SDF-1α could chemotaxize EPCs to reach local wounds, thus further accelerating angiogenesis in the transplant site. The technique described may prove to be a new model for accelerating vascularization of tissue and organ transplants and chronic ischemic wounds.
    Type of Medium: Online Resource
    ISSN: 0963-6897 , 1555-3892
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2016
    detail.hit.zdb_id: 2020466-8
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  • 6
    In: Applied Spectroscopy, SAGE Publications, Vol. 70, No. 9 ( 2016-09), p. 1456-1463
    Abstract: In this study, seven microbial materials (entomogenous fungi Bb3088 mycelia, entomogenous fungi Bb3088 spores, entomogenous fungi Ma2677 mycelia, entomogenous fungi Ma2677 spores, Bacillus subtilis 8204, Staphylococcus aureus 6725, and Saccharomyces cerevisiae 1025) were used to measure electromagnetic (EM) signal extinction. They were subjected to light absorption and reflection measurements in the range of 4000–400 cm −1 (2.5–25 µm) using Fourier transform infrared spectroscopy. The specular reflection spectrum method was used to calculate the real ( n) and imaginary ( k) parts of the complex refractive index. The complex refractive index with real part n and imaginary part k in the infrared band satisfies the following conditions n ≥ 1 and k ≥ 0. The mass extinction coefficient was calculated based on Mie theory. Entomogenous fungi Ma2677 spores and entomogenous fungi Bb3088 spores were selected as EM signal extinction materials in the smoke box test. The transmittances of entomogenous fungi Bb3088 spores and entomogenous fungi Ma2677 spores were 11.63% and 5.42%, and the mass extinction coefficients were 1.8337 m 2 /g and 1.227 m 2 /g. These results showed that entomogenous fungi Bb3088 spores and entomogenous fungi Ma2677 spores have higher extinction characteristics than other microbial materials.
    Type of Medium: Online Resource
    ISSN: 0003-7028 , 1943-3530
    RVK:
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2016
    detail.hit.zdb_id: 1474251-2
    SSG: 11
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  • 7
    Online Resource
    Online Resource
    SAGE Publications ; 2018
    In:  Advances in Mechanical Engineering Vol. 10, No. 2 ( 2018-02), p. 168781401875677-
    In: Advances in Mechanical Engineering, SAGE Publications, Vol. 10, No. 2 ( 2018-02), p. 168781401875677-
    Type of Medium: Online Resource
    ISSN: 1687-8140 , 1687-8140
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2018
    detail.hit.zdb_id: 2501620-9
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  • 8
    Online Resource
    Online Resource
    SAGE Publications ; 2015
    In:  Advances in Mechanical Engineering Vol. 7, No. 11 ( 2015-11-01), p. 168781401561693-
    In: Advances in Mechanical Engineering, SAGE Publications, Vol. 7, No. 11 ( 2015-11-01), p. 168781401561693-
    Abstract: The wind past the ship superstructure produces an unsteady turbulent airwake which has a significant effect on aircraft performance and consequently pilot workload during ship landing process. Computational fluid dynamics simulations of a generic simple frigate shape ship airwake have been performed using the entropy-based detached-eddy simulation method. The results were compared with the steady-state Reynolds-averaged Navier–Stokes calculations and the wind tunnel data, indicating the capability of entropy-based detached-eddy simulation to resolve the unsteady large-scale turbulent features. An analysis of the airwake flow topology at headwind condition highlights the vortex pairing process which dominates the flowfield above the deck. Additionally, the influence of hangar-door state (open, closed or half-open) on the airwake was also investigated in detail. Determination of this complex flow can assist in the definition of safe ship–helicopter operating limits and future ship design.
    Type of Medium: Online Resource
    ISSN: 1687-8140 , 1687-8140
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2015
    detail.hit.zdb_id: 2501620-9
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  • 9
    Online Resource
    Online Resource
    SAGE Publications ; 2019
    In:  Proceedings of the Institution of Mechanical Engineers, Part E: Journal of Process Mechanical Engineering Vol. 233, No. 2 ( 2019-04), p. 403-411
    In: Proceedings of the Institution of Mechanical Engineers, Part E: Journal of Process Mechanical Engineering, SAGE Publications, Vol. 233, No. 2 ( 2019-04), p. 403-411
    Abstract: The severe vibration of a screw compressor outlet piping system caused the premature failures of some thermowells and the unplanned shut down of the compressor system. The root causes of the vibration problem were investigated by numerical simulations. An acoustic model was established to predict the pressure pulsation of the gas inside the pipelines, and two finite element models were built to study the vibration characteristics of the overall piping system and of the thermowells. The numerical results indicated that the vibration problem may be attributed to the excessive pressure nonuniformity of the gas inside the pipelines, low overall stiffness of the piping system and the first-order structural resonance occurred on the thermowells. A pulsation attenuator was added and the pipelines were rearranged to reduce the pressure pulsation, some pipe supports were added to improve the overall stiffness of the piping system, and the thermowells were reinforced to avoid the first-order structural resonance. After the modifications, the field measurement data showed that the vibration of the piping system decreased significantly, and the modified piping system has been operating normally for nearly two years.
    Type of Medium: Online Resource
    ISSN: 0954-4089 , 2041-3009
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2024897-0
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  • 10
    Online Resource
    Online Resource
    SAGE Publications ; 2018
    In:  International Journal of Distributed Sensor Networks Vol. 14, No. 11 ( 2018-11), p. 155014771881447-
    In: International Journal of Distributed Sensor Networks, SAGE Publications, Vol. 14, No. 11 ( 2018-11), p. 155014771881447-
    Abstract: With the rapid development of large-scale complex networks and proliferation of various social network applications, the amount of network traffic data generated is increasing tremendously, and efficient anomaly detection on those massive network traffic data is crucial to many network applications, such as malware detection, load balancing, network intrusion detection. Although there are many methods around for network traffic anomaly detection, they are all designed for single machine, failing to deal with the case that the network traffic data are so large that it is prohibitive for a single computer to store and process the data. To solve these problems, we propose a parallel algorithm based on Isolation Forest and Spark for network traffic anomaly detection. We combine the advantages of Isolation Forest algorithm in network traffic anomaly detection and big data processing capability of Spark technology. Meanwhile, we apply the idea of parallelization to the process of modeling and evaluation. In the calculation process, by assigning tasks to multiple compute nodes, Isolation Forest and Spark can efficiently perform anomaly detection and evaluation process. By this way, we can also solve the problem of computation bottleneck on single machine. Extensive experiments on real world datasets show that our Isolation Forest and Spark is efficient and scales well for anomaly detection on large network traffic data.
    Type of Medium: Online Resource
    ISSN: 1550-1477 , 1550-1477
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2018
    detail.hit.zdb_id: 2192922-1
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