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  • SAGE Publications  (27)
  • 2015-2019  (27)
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  • SAGE Publications  (27)
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  • 2015-2019  (27)
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  • 1
    Online Resource
    Online Resource
    Tetrahydroxystilbene glucoside relieves the chronic inflammatory pain by inhibiting neuronal apoptosis, microglia activation, and GluN2B overexpression in anterior cingulate cortex
    SAGE Publications ; 2018
    In:  Molecular Pain Vol. 14 ( 2018-01), p. 174480691881436-
    Details
    In: Molecular Pain, SAGE Publications, Vol. 14 ( 2018-01), p. 174480691881436-
    Type of Medium: Online Resource
    ISSN: 1744-8069 , 1744-8069
    URL: Article
    DOI: 10.1177/1744806918814367
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2018
    detail.hit.zdb_id: 2174252-2
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  • 2
    Online Resource
    Online Resource
    Health insurance status and risk factors of mortality in patients with septic acute kidney injury in Ningbo, China
    SAGE Publications ; 2019
    In:  Journal of International Medical Research Vol. 47, No. 1 ( 2019-01), p. 370-376
    Details
    In: Journal of International Medical Research, SAGE Publications, Vol. 47, No. 1 ( 2019-01), p. 370-376
    Abstract: To investigate the relationship between health insurance status and outcomes of septic acute kidney injury (AKI) related hospitalizations in an intensive care unit (ICU) in Ningbo, China. Methods For this retrospective study, information was extracted from patients notes and billing records for patients 〉 18 years of age with a diagnosis of AKI admitted to the ICU department, Ningbo First Hospital from April 2013 to March 2018. Results Of the 368 patients with sepsis admitted to ICU, 167 (45%) developed AKI; 95 patients were insured and 72 were uninsured. Compared with insured patients, uninsured patients were younger, had higher Acute Physiology and Chronic Health Evaluation II (APACHE II) and Sequential Organ Failure Assessment (SOFA) scores, but had less catheter interventions and received less renal replacement therapy (RRT). Results from a multivariate analysis showed that independent predictors of ICU mortality were age, APACHE II scores, MODS scores, use of RRT and lack of insurance. Conclusions Uninsured patients with septic AKI were younger, stayed a shorter time in ICU, had higher illness severity scores and a higher ICU mortality than insured patients. Importantly a major risk factor for ICU mortality in this group was lack of insurance.
    Type of Medium: Online Resource
    ISSN: 0300-0605 , 1473-2300
    URL: Article
    DOI: 10.1177/0300060518802526
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2082422-1
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  • 3
    Online Resource
    Online Resource
    Observation satellite attitude estimation using sensor measurement and image registration fusion
    SAGE Publications ; 2018
    In:  Proceedings of the Institution of Mechanical Engineers, Part G: Journal of Aerospace Engineering Vol. 232, No. 7 ( 2018-06), p. 1390-1402
    Details
    In: Proceedings of the Institution of Mechanical Engineers, Part G: Journal of Aerospace Engineering, SAGE Publications, Vol. 232, No. 7 ( 2018-06), p. 1390-1402
    Abstract: In order to enhance the accuracy and the robustness of the attitude determination and control system in observation satellites, a new way to fuse gyro and star tracker measurement with image registration is described. In this method, a novel and complete framework is proposed to estimate the on-orbit attitude variations from multi-spectrum remote sensing images. An extended Kalman filter is derived to calibrate the gyro bias drift and the star tracker error. The new framework is tested with realistically simulated data and remote sensing images based on JL-1 satellite. Simulation and experiment results indicate that based on the image registration, the satellite attitude variations could be detected in real time and applied for the accurate gyro and star tracker bias calibration.
    Type of Medium: Online Resource
    ISSN: 0954-4100 , 2041-3025
    URL: Article
    DOI: 10.1177/0954410017691315
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2018
    detail.hit.zdb_id: 2032759-6
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  • 4
    Online Resource
    Online Resource
    Anxiolytic-Like Effects of Translocator Protein (TSPO) Ligand ZBD-2 in an Animal Model of Chronic Pain
    SAGE Publications ; 2015
    In:  Molecular Pain Vol. 11 ( 2015-08-28), p. s12990-015-0013-
    Details
    In: Molecular Pain, SAGE Publications, Vol. 11 ( 2015-08-28), p. s12990-015-0013-
    Type of Medium: Online Resource
    ISSN: 1744-8069 , 1744-8069
    URL: Article
    DOI: 10.1186/s12990-015-0013-6
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2015
    detail.hit.zdb_id: 2174252-2
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  • 5
    Online Resource
    Online Resource
    Model updating of suspended-dome using artificial neural networks
    SAGE Publications ; 2017
    In:  Advances in Structural Engineering Vol. 20, No. 11 ( 2017-11), p. 1727-1743
    Details
    In: Advances in Structural Engineering, SAGE Publications, Vol. 20, No. 11 ( 2017-11), p. 1727-1743
    Abstract: Differences between the practical suspended-dome and the corresponding numerical model are inevitable. To reduce the existing discrepancy, model updating of a suspended-dome was investigated using the back-propagation network in the article. The article first proposed a method to increase the prediction precision of back-propagation network: reducing the range of the training data for the back-propagation network according to the previous prediction results continuously. Then, some parameters that can be measured are updated by the corresponding measured values directly, and other parameters that cannot be directly measured are updated by the corresponding prediction values from back-propagation network. The results indicate that the updated model can predict the experimental model perfectly, and back-propagation network is effective and accurate to predict the given parameters that cannot be described by an algorithm. The results also confirm that the proposed method to increase the prediction precision of back-propagation network is valid.
    Type of Medium: Online Resource
    ISSN: 1369-4332 , 2048-4011
    URL: Article
    DOI: 10.1177/1369433217693629
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2017
    detail.hit.zdb_id: 2026561-X
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  • 6
    Online Resource
    Online Resource
    T-Helper Type 1-T-Helper Type 2 Shift and Nasal Remodeling after Fine Particulate Matter Exposure in a Rat Model of Allergic Rhinitis
    SAGE Publications ; 2017
    In:  American Journal of Rhinology & Allergy Vol. 31, No. 3 ( 2017-05), p. 148-155
    Details
    In: American Journal of Rhinology & Allergy, SAGE Publications, Vol. 31, No. 3 ( 2017-05), p. 148-155
    Abstract: Exposure to fine particulate matter (particulate matter ≤2.5 μm [PM2.5]) increases the risk of allergic rhinitis (AR), but the underlying mechanisms remains unclear. Thus, we investigated the roles of T-helper (Th)1–Th2 cytokines and nasal remodeling after ambient PM2.5 exposure in a rat model of AR. Methods Female Sprague-Dawley rats were randomized into six groups: a negative control group, a group of healthy rats exposed to 3000 μg/m 3 PM2.5, an ovalbumin (OVA) induced AR model, and three PM2.5-exacerbated AR groups exposed to three different concentrations (200, 1000, and 3000 μg/m 3 ) of PM2.5 for 30 days via inhalation. Nasal symptoms, levels of Th1–Th2 cytokines, the degree of eosinophilia in nasal lavage fluid (NLF), and the messenger RNA (mRNA) expressions of transcription factors GATA-3 and T-bet in the nasal mucosa were measured in each individual rat. Hyperplasia of globet cells and collagen deposition were examined by histology. Results PM2.5 significantly increased the number of sneezes and nasal rubs in rats with AR. PM2.5 also significantly decreased interferon gamma and increased interleukin (IL) 4 and IL-13 expressions as well as the number of eosinophils in NLF. The mRNA expression of GATA-3 in the nasal mucosa of rats with AR was upregulated by PM2.5, whereas T-bet was significantly downregulated. Statistically significant differences in OVA-specific serum immunoglobulin E, goblet cell hyperplasia, collagen deposition, and transforming growth factor beta 1 levels were observed between the PM2.5-exacerbated AR groups and the AR model group. Conclusion Analysis of our data indicated that an increase in the immune response with Th2 polarization and the development of nasal remodeling may be the immunotoxic mechanisms behind the exacerbation of AR after exposure to PM2.5.
    Type of Medium: Online Resource
    ISSN: 1945-8924 , 1945-8932
    URL: Article
    DOI: 10.2500/ajra.2017.31.4437
    RVK:
    XA 20278
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2017
    detail.hit.zdb_id: 2554548-6
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  • 7
    Online Resource
    Online Resource
    Mental Work Demands and Late-Life Cognitive Impairment: Results From the Shanghai Aging Study
    SAGE Publications ; 2019
    In:  Journal of Aging and Health Vol. 31, No. 5 ( 2019-06), p. 883-898
    Details
    In: Journal of Aging and Health, SAGE Publications, Vol. 31, No. 5 ( 2019-06), p. 883-898
    Abstract: Objective: The aim of this study is to explore the association between mental work demands (MWDs) and late-life cognition among Chinese older adults. Method: Data were drawn from the baseline of the Shanghai Aging Study. Results: Among 3,546 participants, the mean MWDs index of participants with dementia, mild cognitive impairment (MCI), and cognitive normal were 2.8 ( SD = 0.5), 2.8 ( SD = 0.5), and 2.9 ( SD = 0.4), respectively. Mini Mental State Examination (MMSE) scores in group with low MWDs level decreased more dramatically by increasing age than that in groups with middle and high MWDs level ( p 〈 .001). In a subgroup of participants with education ≥6 years, we found a positive correlation between MWDs index and MMSE score after adjusting for gender, age, body mass index, income, living alone, smoking, drinking, anxiety, depression, heart disease, hypertension, diabetes, and APOE-ε4 (apolipoprotein), by generalized linear model analysis ( p 〈 .001). Discussion: Our results suggest that long-time mental work stimulation during adulthood would have potential benefits to late-life cognition.
    Type of Medium: Online Resource
    ISSN: 0898-2643 , 1552-6887
    URL: Article
    DOI: 10.1177/0898264318765034
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2034469-7
    SSG: 5,2
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  • 8
    Online Resource
    Online Resource
    Analgesic effects of adenylyl cyclase inhibitor NB001 on bone cancer pain in a mouse model
    SAGE Publications ; 2016
    In:  Molecular Pain Vol. 12 ( 2016-01), p. 174480691665240-
    Details
    In: Molecular Pain, SAGE Publications, Vol. 12 ( 2016-01), p. 174480691665240-
    Type of Medium: Online Resource
    ISSN: 1744-8069 , 1744-8069
    URL: Article
    DOI: 10.1177/1744806916652409
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2016
    detail.hit.zdb_id: 2174252-2
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  • 9
    Online Resource
    Online Resource
    Effect of Chemical Thromboprophylaxis on the Rate of Venous Thromboembolism After Treatment of Foot and Ankle Fractures
    SAGE Publications ; 2016
    In:  Foot & Ankle International Vol. 37, No. 11 ( 2016-11), p. 1218-1224
    Details
    In: Foot & Ankle International, SAGE Publications, Vol. 37, No. 11 ( 2016-11), p. 1218-1224
    Abstract: Venous thromboembolism (VTE) is a well-documented complication in patients with lower limb fractures, but management guidelines for its prevention in isolated foot and ankle fracture patients are conflicting. The aim of this study was to conduct a multicenter, prospective cohort study to define the prevalence of VTE in patients with isolated foot and ankle fractures and determine whether routine prophylaxis is necessary in these patients. Methods: In a double-blind, placebo-controlled study, consecutive patients in 3 hospitals who met our criteria were enrolled. After randomization, patients received either thromboprophylaxis with low-molecular-weight heparin units (LMWH group) or placebo (placebo group) for a period of 2 weeks. All patients underwent routine ultrasonography 1 day preoperatively, 1 week postoperatively, and 1 month postoperatively. Demographic parameters were then collected and compared. Results: Of the 814 patients who met our criteria, 19 patients (2.3%, 95% confidence interval [CI], 0%-31.9%) were found to have objectively confirmed VTE, but none of the patients were symptomatic. Of the 411 patients in the LMWH group, 2 developed VTEs preoperatively and 4 postoperatively; of the 403 patients in the placebo group, 5 developed VTEs preoperatively and 8 postoperatively. The overall incidence of asymptomatic postoperative deep vein thrombosis (DVT) was 0.98% (95% CI 0%-20.3%) in the LMWH group and 2.01% (95% CI 0%-29.5%) in the placebo group without significant difference. Advanced age (odds ratio [OR] 1.050, 95% CI 1.014-1.088, P = .007) and high body mass index (OR 1.201, 95% CI 1.034-1.395, P = .016) were identified as risk factors in predicting occurrence of DVT. No fatal pulmonary emboli or major bleeding complication occurred in either group. Conclusion: Routine anticoagulant prophylaxis was not found to be necessary for patients with foot and ankle fractures, although further investigation with a properly powered study design is required to definitively determine which foot and ankle patients are best served by anticoagulation and which ones are not. Level of Evidence: Level II, prospective comparative study.
    Type of Medium: Online Resource
    ISSN: 1071-1007 , 1944-7876
    URL: Article
    DOI: 10.1177/1071100716658953
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2016
    detail.hit.zdb_id: 2129503-7
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  • 10
    Online Resource
    Online Resource
    Performance tests and modeling on high damping magnetorheological elastomers based on bromobutyl rubber
    SAGE Publications ; 2018
    In:  Journal of Intelligent Material Systems and Structures Vol. 29, No. 6 ( 2018-04), p. 1025-1037
    Details
    In: Journal of Intelligent Material Systems and Structures, SAGE Publications, Vol. 29, No. 6 ( 2018-04), p. 1025-1037
    Abstract: A new kind of magnetorheological elastomer with the matrix of the bromobutyl rubber is developed. The magnetoviscoelasticity properties of the magnetorheological elastomer specimens are investigated with respect to different magnetic fields, displacement amplitudes, and frequencies under sinusoidal loadings. The experimental results show that the shear storage modulus and the loss factor of magnetorheological elastomers increase with the increasing magnetic field, excitation frequency, and the weight fraction of particles, but decrease with the increasing strain amplitude, and the magnetorheological elastomers have a high loss factor which can reach to 0.682. Then, a microphysical model based on the assumption of the chi-square distribution of the distance between adjacent ferromagnetic particles is proposed, which can eliminate the error generated by the assumption of the uniform distribution and describe the magnetorheological effect more exactly. Based on the proposed microphysical model, the magnetoviscoelasticity parameter model is modified to describe the dynamic properties of magnetorheological elastomers. It can be concluded from comparison between the numerical and experimental results that the modified magnetoviscoelasticity parameter model can describe the magnetorheological elastomer’s performance well.
    Type of Medium: Online Resource
    ISSN: 1045-389X , 1530-8138
    URL: Article
    DOI: 10.1177/1045389X17730909
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2018
    detail.hit.zdb_id: 2088313-4
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