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  • SAGE Publications  (7)
  • 2015-2019  (7)
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  • SAGE Publications  (7)
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  • 2015-2019  (7)
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  • 1
    In: Angiology, SAGE Publications, Vol. 66, No. 5 ( 2015-05), p. 448-455
    Abstract: The transradial approach (TRA) has been used as access site for percutaneous coronary intervention (PCI) for years. However, no large sample study has evaluated the effect of TRA in elderly patients. A total of 1098 elderly patients (age ≥ 75 years) who underwent PCI by TRA or transfemoral approach were recruited. A 1:1 matched propensity score analysis was performed to minimize bias. The rates of major adverse cardiovascular events that included death, myocardial infarction (MI), and target vessel revascularization during hospitalization (1.3% vs 6.6%, P = .014) and at 1-year follow-up (6.0% vs 13.9%, P = .019) were significantly lower in the TRA group. Transradial approach was also associated with lower rates of in-hospital MI (1.3% vs 5.3%, P = .046), access-site complications (3.3% vs 9.9%, P = .018), and major bleeding (1.3% vs 5.3%, P = .046). In conclusion, TRA showed better safety in elderly patients; it should be considered as a preferred route for elderly patients.
    Type of Medium: Online Resource
    ISSN: 0003-3197 , 1940-1574
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2015
    detail.hit.zdb_id: 2065911-8
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  • 2
    In: Angiology, SAGE Publications, Vol. 69, No. 6 ( 2018-07), p. 523-531
    Abstract: We developed a new risk factor profile for contrast-induced acute kidney injury (CI-AKI) under a new definition in patients who underwent an emergency percutaneous coronary intervention (PCI). Consecutive patients (n = 1061) who underwent an emergency PCI were divided into a derivation group (n = 761) and a validation group (n = 300). The rates of CI-AKI were 23.5% (definition 1: serum creatinine [SCr] increase ≥25% in 72 hours), 4.3% (definition 2: SCr increase ≥44.2 μmol/L in 72 hours), and 7.0% (definition 3: SCr increase ≥44.2 μmol/L in 7 days). Due to the high sensitivity of definition 1 and the high rate of missed cases for late diagnosis of CI-AKI under definition 2, definition 3 was used in the study. The risk factor profile included body surface area 〈 1.6 m 2 ( P = .030), transient ischemic attack/stroke history ( P = .001), white blood cell count 〉 15.00 × 10 9 /L ( P = .047), estimated glomerular filtration rate 〈 60 mL/min/1.73 m 2 ( P = .002) or baseline SCr 〉 133 μmol/L ( P = .007), intra-aortic balloon pump application ( P = .006), and diuretics administration ( P 〈 .001), showing a significant predictive power in the derivation group and validation group. The new risk factor profile of CI-AKI under a new CI-AKI definition in emergency PCI patients is easily applicable with a useful predictive value.
    Type of Medium: Online Resource
    ISSN: 0003-3197 , 1940-1574
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2018
    detail.hit.zdb_id: 2065911-8
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  • 3
    Online Resource
    Online Resource
    SAGE Publications ; 2019
    In:  Acupuncture in Medicine Vol. 37, No. 4 ( 2019-08), p. 252-258
    In: Acupuncture in Medicine, SAGE Publications, Vol. 37, No. 4 ( 2019-08), p. 252-258
    Abstract: Acupuncture stimulation at GV26 during the acute phase of cerebral ischaemia can effectively reduce brain damage induced by ischaemic injury. However, the time course of the effects of acupuncture stimulation has not yet been thoroughly studied. Objective: To investigate the effects of manual acupuncture (MA) on glutamic acid (Glu) and γ-aminobutyric acid (GABA) expression in the cerebrospinal fluid of rats with middle cerebral artery occlusion (MCAO) and determine whether there is a temporal effect of acupuncture on the treatment of cerebral ischaemia. Methods: We performed thread occlusion of the right middle cerebral artery in rats to establish an animal model of MCAO. Simultaneously, during acupuncture treatment, microdialysis was used to continuously and dynamically observe immediate alterations in amino acid metabolism with acupuncture stimulation after cerebral ischaemia in vivo in this rat model of MCAO. Results: We found that, in comparison with an untreated MCAO group, Glu content was significantly decreased during the first acupuncture stimulation and during the course of the acupuncture treatment in the MCAO+MA group (MCAO vs MCAO+MA: day 1, P=0.032; day 2, P=0.021; day 3, P=0.017). These findings were also seen after the end of treatment when acupuncture was no longer applied (MCAO vs MCAO+MA: day 7, P=0.009). Measurements of GABA content following cerebral ischaemic injury showed that GABA peaks 24 hours after damage, falls thereafter and decreases to baseline levels on day 7. In the MCAO+MA group, GABA content on days 1 to day 2 was lower than in the MCAO group (MCAO+MA vs MCAO: day 1, P=0.003; day 2, P=0.001), although it was higher than in the control group (MCAO+MA vs control: day 1, P=0.024; day 2, P=0.009). GABA content on day 3 and day 7 was higher in the MCAO+MA group than in the MCAO group and the control group (MCAO+MA vs MCAO: day 3, P=0.008; day 7, P=0.013; MCAO+MA vs control: day 3, P=0.002; day 7, P=0.009). Conclusion: Acupuncture stimulation at GV26 can effectively decrease excessive release of Glu induced by ischaemia and maintain the endogenous inhibitory activity of GABA. This phenomenon was seen during the entire course of acupuncture treatment and continued for some time after the end of acupuncture treatment.
    Type of Medium: Online Resource
    ISSN: 0964-5284 , 1759-9873
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2126127-1
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  • 4
    Online Resource
    Online Resource
    SAGE Publications ; 2019
    In:  Advances in Structural Engineering Vol. 22, No. 7 ( 2019-05), p. 1644-1656
    In: Advances in Structural Engineering, SAGE Publications, Vol. 22, No. 7 ( 2019-05), p. 1644-1656
    Abstract: To ensure the safety of cable-stayed bridges, a long-term condition evaluation method has been proposed based on dead load–induced cable forces. To extract dead load–induced cable forces under random vehicle loadings, a novel approach is first developed by integrating influence lines with monitoring data. Then, based on the extracted dead load–induced cable forces, the evaluation algorithm for stay cable systems is presented. In the assessment algorithm, uniform and non-uniform characteristics are taken into account. Finally, the Third Nanjing Yangtze River Bridge, a typical large span cable-stayed bridge, is used to illustrate the effectiveness of the proposed methodology. As a result, the maximum relative error in extraction of dead load–induced cable forces accounts for 4.78% within the studied five stay cables. The precision of the extraction method is acceptable for practical applications since the relative error is less than 5%. Moreover, the bridge is continuously assessed using the dead load–induced cable forces for 5 years. Eliminating the influence of vehicle loadings, the condition of the bridge gradually degrades with time but still remains in good condition. The study not only provides a long-term condition evaluation method for stay cable systems but a dead load–induced extraction approach under random vehicle loadings, which will help bridge owners know well the condition of bridges to make appropriate maintenance decisions.
    Type of Medium: Online Resource
    ISSN: 1369-4332 , 2048-4011
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2026561-X
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  • 5
    In: Clinical and Applied Thrombosis/Hemostasis, SAGE Publications, Vol. 25 ( 2019-01-01), p. 107602961985363-
    Abstract: The Patterns of non-Adherence to Anti-Platelet Regimen in Stented Patients (PARIS) thrombotic risk score is a novel score for predicting the risk of coronary thrombotic events after percutaneous coronary intervention (PCI). We assessed the prognostic value of this score for mortality in patients with PCI. In this prospective, observational study, we enrolled 10 724 consecutive patients underwent PCI. The primary end point was all-cause death and the secondary end point was major adverse cardiovascular and cerebrovascular events (MACCE) as a composite of all-cause death, myocardial infarction, revascularization, stent thrombosis, or stroke. Among 9782 patients without in-hospital events, a total of 97 deaths and 1002 MACCE occurred during the 2-year follow-up. The mortality risk of patients in the high-risk group was 2.31 times higher than that in the low-risk group (hazard ratio, 2.31; P = .001). This risk score showed prognostic value in evaluating mortality (area under the receiver operating characteristic curve [AUROC], 0.607; 95% confidence interval [CI] , 0.551-0.663) and MACCE (AUROC, 0.544; 95% CI, 0.526-0.563; both P 〈 .001). The prognostic value of mortality was higher than that of MACCE (Z = 2.09, P = .04). The PARIS thrombotic risk score shows modest prognostic value for mortality and MACCE, and the prognostic value of mortality is better than that of MACCE.
    Type of Medium: Online Resource
    ISSN: 1076-0296 , 1938-2723
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2230591-9
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  • 6
    In: Angiology, SAGE Publications, Vol. 69, No. 6 ( 2018-07), p. 540-547
    Abstract: To investigate the impact of diabetic status on 2-year clinical outcomes in Chinese patients undergoing contemporary percutaneous coronary intervention (PCI) treatment. Methods and Results: A total of 10 724 consecutive patients underwent PCI at Fu Wai Hospital were prospectively collected. Two-year clinical outcomes were compared between patients with and without diabetes mellitus (DM). Diabetic patients had more baseline clinical risks and more extensive coronary disease. During 2-year follow-up, the rates of all-cause death, myocardial infarction (MI), revascularization, and major adverse cardiac events (MACE) were significantly higher in DM group. After multivariable-adjusted Cox regression analysis, DM was an independent risk factor for MACE but not for the individual components of MACE. After performing propensity score matching, rates of all-cause death, MI, revascularization, stroke, stent thrombosis, and MACE were not significantly different between the 2 groups, and DM was not predictive of MACE and any clinical adverse outcomes. Conclusions: Diabetic patients who underwent PCI had worse prognosis including death and repeat revascularization during 2-year follow-up, but DM was not an independent risk factor for adverse clinical outcomes.
    Type of Medium: Online Resource
    ISSN: 0003-3197 , 1940-1574
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2018
    detail.hit.zdb_id: 2065911-8
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  • 7
    Online Resource
    Online Resource
    SAGE Publications ; 2018
    In:  Proceedings of the Institution of Mechanical Engineers, Part G: Journal of Aerospace Engineering Vol. 232, No. 12 ( 2018-09), p. 2195-2213
    In: Proceedings of the Institution of Mechanical Engineers, Part G: Journal of Aerospace Engineering, SAGE Publications, Vol. 232, No. 12 ( 2018-09), p. 2195-2213
    Abstract: Stochastic optimization methods have been widely employed to find solutions to structural design optimization problems in the past two decades, especially for truss structures. The primary aim of this study is to introduce a design optimization method combining an augmented Lagrangian function and teaching–learning-based optimization for truss and nontruss structural design optimization. The augmented Lagrangian function serves as a constraint-handling tool in the proposed method and converts a constrained optimization problem into an unconstrained one. On the other hand, teaching–learning-based optimization is employed to resolve the transformed, unconstrained optimization problems. Since the proper values of the Lagrangian multipliers and penalty factors are unknown in advance, the proposed method is implemented in an iterative way to avoid the issue of selecting them, i.e. the Lagrangian multipliers and penalty factors are automatically updated according to the violation level of all constraints. To examine the performance of the proposed method, it is applied on a group of benchmark truss optimization problems and a group of nontruss optimization problems of aircraft wing structures. The computational results obtained by the proposed method are compared to the results produced by both other version of teaching–learning-based optimization and stochastic optimization methods.
    Type of Medium: Online Resource
    ISSN: 0954-4100 , 2041-3025
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2018
    detail.hit.zdb_id: 2032759-6
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