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  • SAGE Publications  (61)
  • 2015-2019  (61)
  • 1
    Online Resource
    Online Resource
    3D-Printed Poly(ε-caprolactone) Scaffold Augmented With Mesenchymal Stem Cells for Total Meniscal Substitution: A 12- and 24-Week Animal Study in a Rabbit Model
    SAGE Publications ; 2017
    In:  The American Journal of Sports Medicine Vol. 45, No. 7 ( 2017-06), p. 1497-1511
    Details
    In: The American Journal of Sports Medicine, SAGE Publications, Vol. 45, No. 7 ( 2017-06), p. 1497-1511
    Abstract: Total meniscectomy leads to knee osteoarthritis in the long term. The poly(ε-caprolactone) (PCL) scaffold is a promising material for meniscal tissue regeneration, but cell-free scaffolds result in relatively poor tissue regeneration and lead to joint degeneration. Hypothesis: A novel, 3-dimensional (3D)–printed PCL scaffold augmented with mesenchymal stem cells (MSCs) would offer benefits in meniscal regeneration and cartilage protection. Study Design: Controlled laboratory study. Methods: PCL meniscal scaffolds were 3D printed and seeded with bone marrow–derived MSCs. Seventy-two New Zealand White rabbits were included and were divided into 4 groups: cell-seeded scaffold, cell-free scaffold, sham operation, and total meniscectomy alone. The regeneration of the implanted tissue and the degeneration of articular cartilage were assessed by gross and microscopic (histological and scanning electron microscope) analysis at 12 and 24 weeks postoperatively. The mechanical properties of implants were also evaluated (tensile and compressive testing). Results: Compared with the cell-free group, the cell-seeded scaffold showed notably better gross appearance, with a shiny white color and a smooth surface. Fibrochondrocytes with extracellular collagen type I, II, and III and proteoglycans were found in both seeded and cell-free scaffold implants at 12 and 24 weeks, while the results were significantly better for the cell-seeded group at week 24. Furthermore, the cell-seeded group presented notably lower cartilage degeneration in both femur and tibia compared with the cell-free or meniscectomy group. Both the tensile and compressive properties of the implants in the cell-seeded group were significantly increased compared with those of the cell-free group. Conclusion: Seeding MSCs in the PCL scaffold increased its fibrocartilaginous tissue regeneration and mechanical strength, providing a functional replacement to protect articular cartilage from damage after total meniscectomy. Clinical Relevance: The study suggests the potential of the novel 3D PCL scaffold augmented with MSCs as an alternative meniscal substitution, although this approach requires further improvement before being used in clinical practice.
    Type of Medium: Online Resource
    ISSN: 0363-5465 , 1552-3365
    URL: Article
    DOI: 10.1177/0363546517691513
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2017
    detail.hit.zdb_id: 2063945-4
    SSG: 31
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  • 2
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    Wood plastic composites : Using carbon fiber to create electromagnetic shielding effectiveness
    SAGE Publications ; 2015
    In:  Journal of Thermoplastic Composite Materials Vol. 28, No. 7 ( 2015-07), p. 1047-1057
    Details
    In: Journal of Thermoplastic Composite Materials, SAGE Publications, Vol. 28, No. 7 ( 2015-07), p. 1047-1057
    Abstract: This study uses coir from agricultural waste, electromagnetic shielding carbon fiber, impact-resistant polypropylene (PP), and methylmaleic anhydride- grafted PP (MA- g-PP) to make wood plastic composites (WPCs). According to the experimental results, when coir and carbon fiber are at a ratio of 3:12, the resulting WPC exhibits an maximum electromagnetic shielding effectiveness (EMSE) of −25 dB, which reaches the protective grade of staple merchandise. At fibers ratio of 3:12, the tensile strength is improved by 10% more than at ratio of 15:0; and the increased flexural strength is by 20% accordingly. A multiblending process is used to simulate the recycling and explores its thermodestruction of the resulting WPC. With a ratio of 3:12, the WPC still has an EMSE of −25 dB at nine cycles of multiblending; however, its tensile and flexural strengths both decrease by 10%.
    Type of Medium: Online Resource
    ISSN: 0892-7057 , 1530-7980
    URL: Article
    DOI: 10.1177/0892705713496109
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2015
    detail.hit.zdb_id: 2098671-3
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  • 3
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    A Novel IKP-Based Biometric Recognition Using Mobile Phone Camera
    SAGE Publications ; 2015
    In:  International Journal of Distributed Sensor Networks Vol. 2015 ( 2015), p. 1-11
    Details
    In: International Journal of Distributed Sensor Networks, SAGE Publications, Vol. 2015 ( 2015), p. 1-11
    Abstract: This paper explores an inner-knuckle-print (IKP) biometric recognition, based on mobile phone. Since IKP characteristics are captured by using mobile phone camera, the greatest challenge is that IKP images from the same hand have different illumination, posture, and background. In order to construct autonomous and robust recognition, we present a range of techniques as follows. Firstly, the hand region is preprocessed by using mean shift (MS) and K -means clustering. Secondly, the region of interest (ROI) of IKP is segmented and normalized. Thirdly, the IKP feature is extracted by using 2D Gabor filter with proper orientation and frequency. Finally, histogram of orientation gradient (HOG) algorithm is applied for matching. According to the experimental results, the proposed method is capable of achieving considerable recognition accuracy.
    Type of Medium: Online Resource
    ISSN: 1550-1329 , 1550-1477
    URL: Article
    DOI: 10.1155/2015/705710
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2015
    detail.hit.zdb_id: 2192922-1
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  • 4
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    Quantitative measurements of brain iron deposition in cirrhotic patients using susceptibility mapping
    SAGE Publications ; 2015
    In:  Acta Radiologica Vol. 56, No. 3 ( 2015-03), p. 339-346
    Details
    In: Acta Radiologica, SAGE Publications, Vol. 56, No. 3 ( 2015-03), p. 339-346
    Abstract: Susceptibility-weighted imaging (SWI) has been used to detect micro-bleeds and iron deposits in the brain. However, no reports have been published on the application of SWI in studying iron changes in the brain of cirrhotic patients. Purpose To compare the susceptibility of different brain structures in cirrhotic patients with that in healthy controls and to evaluate susceptibility as a potential biomarker and correlate the measured susceptibility and cadaveric brain iron concentration for a variety of brain structures. Material and Methods Forty-three cirrhotic patients (27 men, 16 women; mean age, 50 ± 9 years) and 34 age- and sex-matched healthy controls (22 men, 12 women; mean age, 47 ± 7 years) were included in this retrospective study. Susceptibility was measured in the frontal white matter, basal ganglia, midbrain, and dentate nucleus and compared with results gathered from two postmortem brain studies. Correlation between susceptibility and clinical biomarkers and neuropsychiatric tests scores was calculated. Results In cirrhotic patients, the susceptibility of left frontal white matter, bilateral caudate head, and right substantia nigra was higher than that in healthy controls ( P  〈  0.05). There was a positive correlation between susceptibility and iron concentration from one postmortem brain study (r = 0.835, P = 0.01) in eight deep grey matter structures and another in five brain structures (r = 0.900, P = 0.03). The susceptibility of right caudate head (r = 0.402) and left caudate head (r = 0.408) correlated with neuropsychological test scores (both P  〈  0.05). Conclusion Abnormal iron deposits occur in cirrhotic patients and abnormal susceptibility of some brain regions appears to reflect neurocognitive changes.
    Type of Medium: Online Resource
    ISSN: 0284-1851 , 1600-0455
    URL: Article
    DOI: 10.1177/0284185114525374
    RVK:
    XA 10000
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2015
    detail.hit.zdb_id: 2024579-8
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  • 5
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    Predicting the grinding force of titanium matrix composites using the genetic algorithm optimizing back-propagation neural network model
    SAGE Publications ; 2019
    In:  Proceedings of the Institution of Mechanical Engineers, Part B: Journal of Engineering Manufacture Vol. 233, No. 4 ( 2019-03), p. 1157-1167
    Details
    In: Proceedings of the Institution of Mechanical Engineers, Part B: Journal of Engineering Manufacture, SAGE Publications, Vol. 233, No. 4 ( 2019-03), p. 1157-1167
    Abstract: A back-propagation neural network BP model and a genetic algorithm optimizing back-propagation neural network (GA-BP) model are proposed to predict the grinding forces produced during the creep-feed deep grinding of titanium matrix composites. These models consider quantitative and non-quantitative grinding parameters (e.g. up-grinding mode and down-grinding mode) as inputs. Comparative results show that the GA-BP model has better prediction accuracy (e.g. up to 95%) than the conventional regression model and the BP model. Specific grinding energy was calculated against the grinding parameters and grinding modes based on the grinding forces predicted by the GA-BP model.
    Type of Medium: Online Resource
    ISSN: 0954-4054 , 2041-2975
    URL: Article
    DOI: 10.1177/0954405418780166
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2032745-6
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  • 6
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    Long-term Observation of Respiratory Function After Unilateral Phrenic Nerve and Multiple Intercostal Nerve Transfer for Avulsed Brachial Plexus Injury
    SAGE Publications ; 2016
    In:  HAND Vol. 11, No. 1_suppl ( 2016-09), p. 23S-24S
    Details
    In: HAND, SAGE Publications, Vol. 11, No. 1_suppl ( 2016-09), p. 23S-24S
    Abstract: Objective: Either phrenic nerve transfer (PNT) or multiple intercostal nerve transfer (MIT) alone was reported having no significant impact on pulmonary function in short or medium term. But it has rarely been reported whether the combination of PNT-MIT could influence respiratory function in the long term. In this study, pulmonary and diaphragmatic functions were compared between PNT and PNT-MIT after 7 to 19 years (mean 10 years) postoperatively. Methods: Twenty-three adult patients with brachial plexus avulsion injuries (BPAI) who underwent PNT-MIT were compared with 19 corresponding adult patients who underwent PNT only. Pulmonary function testing, phrenic nerve conduction study, and chest fluoroscopy were performed to assess ventilation, diaphragmatic response, and excursion. In the PNT-MIT group, further comparison was performed to investigate whether the number of transferred intercostal nerves and the timing of MIT would influence the results. Results: In PNT-MIT group, forced vital capacity (FVC), forced expiratory volume in one second (FEV1), and total lung capacity (TLC) were 73.69%, 72.04%, and 74.81%, respectively, of predicted values without significant differences from the PNT group. Diaphragmatic paralysis permanently existed with hemidiaphragm elevation of 1 to 1.5 intercostal spaces (ICSs) and near one ICS reduced excursion. No statistically significant difference was found between PNT and PNT-MIT groups. Furthermore, in the PNT-MIT group, the transfer of 3 and 4 intercostal nerves resulted in no further decrease in pulmonary function than that of 2 intercostal nerves. No significant difference was found when PNT-MIT was performed at the same stage or at an interval of 1 or 2 months. Conclusions: In the long-term observation, PNT-MIT did not result in additional impairment in respiratory function in adult patients compared with PNT alone. Transfer of 2 to 4 intercostal nerves at 1- to 2-month delay after PNT is a safe method for treating BPAI.
    Type of Medium: Online Resource
    ISSN: 1558-9447 , 1558-9455
    URL: Article
    DOI: 10.1177/1558944716660555vv
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2016
    detail.hit.zdb_id: 2316440-2
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  • 7
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    Resveratrol supplementation restores high-fat diet-induced insulin secretion dysfunction by increasing mitochondrial function in islet
    SAGE Publications ; 2015
    In:  Experimental Biology and Medicine Vol. 240, No. 2 ( 2015-02), p. 220-229
    Details
    In: Experimental Biology and Medicine, SAGE Publications, Vol. 240, No. 2 ( 2015-02), p. 220-229
    Abstract: Resveratrol (RSV), a natural compound, is known for its effects on energy homeostasis. Here we investigated the effects of RSV and possible mechanism in insulin secretion of high-fat diet rats. Rats were randomly divided into three groups as follows: NC group (animals were fed ad libitum with normal chow for 8 weeks), HF group (animals were fed ad libitum with high-fat diet for 8 weeks), and HFR group (animals were treated with high-fat diet and administered with RSV for 8 weeks). Insulin secretion ability of rats was assessed by hyperglycemic clamp. Mitochondrial biogenesis genes, mitochondrial respiratory chain activities, reactive oxidative species (ROS), and several mitochondrial antioxidant enzyme activities were evaluated in islet. We found that HF group rats clearly showed low insulin secretion and mitochondrial complex dysfunction. Expression of silent mating type information regulation 2 homolog- 1 (SIRT1) and related mitochondrial biogenesis were significantly decreased. However, RSV administration group (HFR) showed a marked potentiation of glucose-stimulated insulin secretion. This effect was associated with elevated SIRT1 protein expression and antioxidant enzyme activities, resulting in increased mitochondrial respiratory chain activities and decreased ROS level. This study suggests that RSV may increase islet mitochondrial complex activities and antioxidant function to restore insulin secretion dysfunction induced by high-fat diet.
    Type of Medium: Online Resource
    ISSN: 1535-3702 , 1535-3699
    URL: Article
    DOI: 10.1177/1535370214548998
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2015
    detail.hit.zdb_id: 2020856-X
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  • 8
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    Adaptive state feedback control for nonlinear systems with multiple interval time-varying delays and non-symmetric dead-zone input: A Lyapunov-Krasovskii approach
    SAGE Publications ; 2019
    In:  Transactions of the Institute of Measurement and Control Vol. 41, No. 14 ( 2019-10), p. 3979-3990
    Details
    In: Transactions of the Institute of Measurement and Control, SAGE Publications, Vol. 41, No. 14 ( 2019-10), p. 3979-3990
    Abstract: This paper addresses the stability analysis and adaptive state feedback control for a class of nonlinear discrete-time systems with multiple interval time-varying delays and non-symmetric dead-zone input. The multiple interval time-varying delays uncertainties are bounded by the nonlinear function with unknown coefficients. The non-symmetric dead-zone input without the knowledge of the dead-zone parameters is considered for the nonlinear system. The smooth adaptive state feedback controller is designed. By introducing the new Lyapunov-Krasovskii functional, it can be seen that the solutions of the closed-loop error system converge to an adjustable bounded region. In general, the proposed adaptive state feedback control strategy does not require the knowledge of maximum and minimum values for the characteristic slopes, and the knowledge of all system states. The control design conditions are relaxed because the system output is available for the controller design. Finally, three simulation examples are performed to show the effectiveness of the proposed methods.
    Type of Medium: Online Resource
    ISSN: 0142-3312 , 1477-0369
    URL: Article
    DOI: 10.1177/0142331219842284
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2025882-3
    SSG: 3,2
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  • 9
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    Aerodynamic noise radiating from the inter-coach windshield region of a high-speed train
    SAGE Publications ; 2018
    In:  Journal of Low Frequency Noise, Vibration and Active Control Vol. 37, No. 3 ( 2018-09), p. 590-610
    Details
    In: Journal of Low Frequency Noise, Vibration and Active Control, SAGE Publications, Vol. 37, No. 3 ( 2018-09), p. 590-610
    Abstract: The aerodynamic noise has been the dominant factor of noise issues in high-speed train as the traveling speed increases. The inter-coach windshield region is considered as one of the main aerodynamic noise sources; however, the corresponding characteristics have not been well investigated. In this paper, a hybrid method is adopted to study the aerodynamic noise around the windshield region. The effectiveness of simulation methods is validated by a simple case of cavity noise. After that, the Reynolds-averaged Navier–Stokes simulation is used to obtain the characteristics of flow field around the windshield region, which determine the aerodynamic noise. Then the nonlinear acoustic solver approach is employed to acquire the near-field noise, while the Ffowcs-Williams/Hawking equation is solved for far-field acoustic propagation. The results indicate that the windshield region is approximately an open cavity filled with severe disturbance flow. According to the analysis of sound pressure distribution in the near-acoustic field, both sides of the windshield region appear symmetrical two-lobe shape with different directivities. The results of frequency spectrum analysis indicate that the aerodynamic noise inside inter-coach space is a typical broadband one from 100 Hz to 5k Hz, and most acoustic power is restricted in the low-medium frequency range (below 500 Hz). In addition, the acoustic power in the low frequency range (below 100 Hz) is closely related to the cavity resonance with the resonance peak frequency of 42 Hz. The overall sound pressure level at different speeds shows that the acoustic power grows approximately 5th power of the train speed. Two forms of outside-windshields are designed to reduce the noise around the windshield region, and the results show the full-windshield form is better in noise reduction, which apparently eliminates interior cavity noise of inter-coach space and lessens the overall sound pressure level on the sides of near-field by about 13 dB.
    Type of Medium: Online Resource
    ISSN: 1461-3484 , 2048-4046
    URL: Article
    DOI: 10.1177/1461348417747178
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2018
    detail.hit.zdb_id: 2025887-2
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  • 10
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    Local and Extensive Neuroplasticity in Carpal Tunnel Syndrome: A Resting-State fMRI Study
    SAGE Publications ; 2017
    In:  Neurorehabilitation and Neural Repair Vol. 31, No. 10-11 ( 2017-10), p. 898-909
    Details
    In: Neurorehabilitation and Neural Repair, SAGE Publications, Vol. 31, No. 10-11 ( 2017-10), p. 898-909
    Abstract: Carpal tunnel syndrome (CTS) is a most common peripheral nerve entrapment neuropathy characterized by sensorimotor deficits in median nerve innervated digits. Block-design task-related functional magnetic resonance imaging (fMRI) studies have been used to investigate CTS-related neuroplasticity in the primary somatosensory cortices. However, considering the persistence of digital paresthesia syndrome caused by median nerve entrapment, spontaneous neuronal activity might provide a better understanding of CTS-related neuroplasticity, which remains unexplored. The present study aimed to investigate both local and extensive spontaneous neuronal activities with resting-state fMRI. A total of 28 bilateral CTS patients and 24 normal controls were recruited, and metrics, including amplitude of low-frequency fluctuation (ALFF) and voxel-wise functional connectivity (FC), were used to explore synaptic activity at different spatial scales. Correlations with clinical measures were further investigated by linear regression. Decreased amplitudes of low-frequency fluctuation were observed in the bilateral primary sensory cortex (SI) and secondary sensory cortex (SII) in CTS patients (AlphaSim corrected P 〈 .05). This was found to be negatively related to the sensory thresholds of corresponding median nerve innervated fingers. In the voxel-wise FC analysis, with predefined seed regions of interest in the bilateral SI and primary motor cortex, we observed decreased interhemispheric and increased intrahemispheric FC. Additionally, both interhemispheric and intrahemispheric FC were found to be significantly correlated with the mean ALFF.
    Type of Medium: Online Resource
    ISSN: 1545-9683 , 1552-6844
    URL: Article
    DOI: 10.1177/1545968317723749
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2017
    detail.hit.zdb_id: 2100545-X
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