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  • SAGE Publications  (274)
  • 2015-2019  (274)
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  • SAGE Publications  (274)
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  • 2015-2019  (274)
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  • 1
    Online Resource
    Online Resource
    SAGE Publications ; 2019
    In:  Journal of International Medical Research Vol. 47, No. 9 ( 2019-09), p. 4095-4103
    In: Journal of International Medical Research, SAGE Publications, Vol. 47, No. 9 ( 2019-09), p. 4095-4103
    Abstract: Gut microbes are known as the body’s second gene pool. Symbiotic intestinal bacteria play a major role in maintaining balance in humans. Bad eating habits, antibiotic abuse, diseases, and a poor living environment have a negative effect on intestinal flora. Abnormal intestinal microbes are prone to cause a variety of diseases, affecting life expectancy and long-term quality of life, especially in older people. Several recent studies have found a close association between intestinal microorganisms and osteoporosis. The potential mechanism of intestinal flora affecting bone formation or destruction by mediating nitric oxide, the immune and endocrine systems, and other factors is briefly described in this review. All of these factors may be responsible for the intestinal flora that causes osteoporosis. Studying the relationship between intestinal flora and bone health not only provides new ideas for studying the role of intestinal microorganism in osteoporosis, but also provides a new therapeutic direction for clinically refractory osteoporosis. Study of the relationship between intestinal microbiota and osteoporosis is important for maintaining bone health and minimizing osteoporosis.
    Type of Medium: Online Resource
    ISSN: 0300-0605 , 1473-2300
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2082422-1
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  • 2
    In: Clinical Rehabilitation, SAGE Publications, Vol. 33, No. 9 ( 2019-09), p. 1479-1491
    Abstract: The aim of this study was to validate a novel pictorial-based Longshi Scale for evaluating a patient’s disability by healthcare professionals and non-professionals. Design: Prospective study. Setting: Rehabilitation departments from a grade A, class 3 public hospital, a grade B, class 2 public hospital, and a private hospital and seven community rehabilitation centers. Subjects: A total of 618 patients and 251 patients with functional disabilities were recruited in a two-phase study, respectively. Main measures: Outcome measure: pictorial scale of activities of daily living (ADLs, Longshi Scale). Reference measure: Barthel Index. The Spearman correlation coefficient was used to analyze the validity of Longshi Scale against Barthel Index. Results: In phase 1 study, from March 2016 to August 2016, the results demonstrated that the Longshi Scale was both reliable and valid (intraclass correlation coefficient based on two-way random effect (ICC 2,1 ) = 0.877–0.974 for intra-rater reliability; ICC 2,1 = 0.928–0.979; κ = 0.679–1.000 for inter-rater reliability; intraclass correlation coefficient based on one-way random effect (ICC 1,1 ) = 0.921–0.984 for test–retest reliability and Spearman correlation coefficient = 0.836–0.899). In the second phase, in March 2018, results further demonstrated that the Longshi Scale had good inter-rater and intra-rater reliability among healthcare professionals and non-professionals including therapists, interns, and personal care aids (ICC 1,1 = 0.822–0.882 on Day 1; ICC 1,1 = 0.842–0.899 on Day 7 for inter-rater reliability). In addition, the Longshi Scale decreased assessment time significantly, compared with the Barthel Index assessment ( P 〈 0.01). Conclusion: The Longshi Scale could potentially provide an efficient way for healthcare professionals and non-professionals who may have minimal training to assess the ADLs of functionally disabled patients.
    Type of Medium: Online Resource
    ISSN: 0269-2155 , 1477-0873
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2028323-4
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  • 3
    Online Resource
    Online Resource
    SAGE Publications ; 2018
    In:  Advances in Mechanical Engineering Vol. 10, No. 10 ( 2018-10), p. 168781401880145-
    In: Advances in Mechanical Engineering, SAGE Publications, Vol. 10, No. 10 ( 2018-10), p. 168781401880145-
    Abstract: The rolling control of a car that focuses on reducing the roll angle passively has limited performance of increasing handling stability, passing speed, ride comfort, and rollover prevention while turning. This project presents a method for controlling an automobile to tilt toward the turning direction using active suspension. A 6-degree-of-freedom vehicle model with a 2-degree-of-freedom steering model and a 4-degree-of-freedom tilting model is established. The active tilt sliding mode controller, which causes zero steady-state tilt angle error, is established after the desired tilt angle is determined by dynamic analysis. Simulation results confirm the effectiveness of the control method. The proposed controller reduces the perceived lateral acceleration and the lateral load transfer rate, thereby effectively improving handling stability, ride comfort, and vehicle speed, meanwhile decreasing the possibility of rollover while turning.
    Type of Medium: Online Resource
    ISSN: 1687-8140 , 1687-8140
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2018
    detail.hit.zdb_id: 2501620-9
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  • 4
    Online Resource
    Online Resource
    SAGE Publications ; 2016
    In:  Transportation Research Record: Journal of the Transportation Research Board Vol. 2579, No. 1 ( 2016-01), p. 40-47
    In: Transportation Research Record: Journal of the Transportation Research Board, SAGE Publications, Vol. 2579, No. 1 ( 2016-01), p. 40-47
    Abstract: Uneven settlement and variation in track stiffness are inherent issues of culvert–embankment transition zones. Therefore, the construction of a shield tunnel (a temporary support structure for tunnel construction) in the vicinity of a transition zone may aggravate track geometry deterioration, increase maintenance demand, and cause poor ride quality. This study investigated the influence of shield tunnel construction on the distribution of soil dynamic stress. A construction project of shield tunnels for a metro line beneath an existing railroad was employed as a case study. A plane strain model that was realized by the finite element analysis method was employed to investigate the distribution discipline of the soil dynamic stress in transition zones, which was induced by the passing train and the shield tunnel beneath the railway. The results indicate that the existence of a shield tunnel structure will increase the soil dynamic stress in the transition zone. Because of the tunnel structure, the soil dynamic stress is 38% greater than the soil dynamic stress in the case without a tunnel at a depth of 16 m. Consequently, a recommended treatment is introduced according to the properties of the surrounding soil. Numerical simulation revealed that this treatment is appropriate for reducing the soil dynamic stress in a transition zone.
    Type of Medium: Online Resource
    ISSN: 0361-1981 , 2169-4052
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2016
    detail.hit.zdb_id: 2403378-9
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  • 5
    In: Journal of International Medical Research, SAGE Publications, Vol. 43, No. 1 ( 2015-02), p. 139-146
    Abstract: To investigate the relationships between body mass index (BMI) and sex, and asthma-like disease and current wheeze in Han children in Nanjing, China. Methods Han children aged 3–14 years were recruited. Height and weight were measured; individuals were classified into obesity, thinness and normal-weight groups on the basis of the calculated BMI. Questionnaires were used to measure prevalence of asthma-like disease and current wheeze. Results were evaluated using the χ 2 -test, odds ratios with 95% confidence intervals and multivariate logistic regression analyses. Results In total 12 092 children (6 331 boys and 5 761 girls) were included. Rates of normal weight, obesity and thinness were 8915/12 092 (73.73%), 1479/12 092 (12.23%) and 1698/12 092 (14.04%), respectively. Asthma-like disease and current wheeze were reported in 2051/12 092 (16.96%) and 400/12 092 (3.31%), respectively. An increased BMI was associated with a greater risk of asthma-like disease; this relationship was strongest in girls. Current wheeze was associated positively with obesity and negatively with thinness, but only among boys. Boys had a greater risk of asthma-like disease and current wheeze than girls. Conclusions BMI and sex were associated independently with the prevalence of asthma-like disease and current wheeze in Han Chinese children.
    Type of Medium: Online Resource
    ISSN: 0300-0605 , 1473-2300
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2015
    detail.hit.zdb_id: 2082422-1
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  • 6
    Online Resource
    Online Resource
    SAGE Publications ; 2017
    In:  Transportation Research Record: Journal of the Transportation Research Board Vol. 2607, No. 1 ( 2017-01), p. 7-14
    In: Transportation Research Record: Journal of the Transportation Research Board, SAGE Publications, Vol. 2607, No. 1 ( 2017-01), p. 7-14
    Abstract: Uneven subgrade settlement associated with rail deflection occurs mainly in the bridge–embankment transition zones of high-speed railways. An iterative method of computation is proposed for studying such uneven settlement in these zones. A vehicle–track–subgrade model is used to investigate the vehicle–track interactions and the deviator stress field of the transition zone, and a soil cumulative plastic strain model is used to obtain the deterioration process of uneven settlement in the transition zone. Results indicate that uneven settlement caused by train loads in the transition zone tends to plateau at 40,000 repeated load applications. Sub-grade settlement changes abruptly in the first measured 5 m, as well as from 25 to 30 m from the abutment; these two regions should be adequately strengthened and should receive more attention for track maintenance.
    Type of Medium: Online Resource
    ISSN: 0361-1981 , 2169-4052
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2017
    detail.hit.zdb_id: 2403378-9
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  • 7
    Online Resource
    Online Resource
    SAGE Publications ; 2016
    In:  International Journal of Distributed Sensor Networks Vol. 12, No. 3 ( 2016-03-01), p. 5828956-
    In: International Journal of Distributed Sensor Networks, SAGE Publications, Vol. 12, No. 3 ( 2016-03-01), p. 5828956-
    Abstract: For the purpose of balancing energy consumption of nodes in Wireless Sensor Networks (WSNs for short), a type of energy hole avoiding method based on synchronization of nodes in adjacent annuluses (SNAA for short) is proposed in this paper. The circular network is divided into virtual annuluses with the same width. Nodes are deployed nonuniformly and their number increases in geometric progression from the outer annuluses to the inner ones which could effectively reduce the work load on nodes near the center. Moreover, each node could find its optimal parent by considering the residual energy of each candidate as well as the distance between the two nodes in adjacent annuluses. And on the basis of synchronization of nodes between adjacent annuluses during their transmitting and receiving phases, a sleep scheduling strategy is also proposed to further reduce the energy consumption of nodes in idle listening mode. Simulation results show that SNAA has a superior performance on energy consumption balance compared to the algorithm proposed (Liu et al., 2013; Wu et al., 2008) and it could also mitigate the energy hole problem in WSNs.
    Type of Medium: Online Resource
    ISSN: 1550-1477 , 1550-1477
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2016
    detail.hit.zdb_id: 2192922-1
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  • 8
    Online Resource
    Online Resource
    SAGE Publications ; 2017
    In:  Advances in Mechanical Engineering Vol. 9, No. 11 ( 2017-11), p. 168781401773726-
    In: Advances in Mechanical Engineering, SAGE Publications, Vol. 9, No. 11 ( 2017-11), p. 168781401773726-
    Type of Medium: Online Resource
    ISSN: 1687-8140 , 1687-8140
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2017
    detail.hit.zdb_id: 2501620-9
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  • 9
    In: Therapeutic Advances in Gastroenterology, SAGE Publications, Vol. 11 ( 2018-01-01), p. 1756283X1774747-
    Abstract: Gastric antral vascular ectasia (GAVE) is an uncommon but important cause of chronic gastrointestinal bleeding. It is often associated with systemic diseases such as autoimmune diseases, liver cirrhosis, chronic renal insufficiency and cardiovascular disease. The etiology of GAVE has not been fully explored and remains controversial. Diagnosis is mainly based on endoscopic presentation with flat or raised erythematous stripes radiating from the pylorus to the antrum and resembles a watermelon. Clinical presentation may range from iron-deficiency anemia secondary to occult blood loss, melena to hematemesis. In past decades, many therapeutic modalities including medical, endoscopic and surgical intervention have been introduced for GAVE treatment with variable efficacy. Herein, we review the efficacy and safety of these treatment options for GAVE.
    Type of Medium: Online Resource
    ISSN: 1756-2848 , 1756-2848
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2018
    detail.hit.zdb_id: 2440710-0
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  • 10
    In: Diabetes and Vascular Disease Research, SAGE Publications, Vol. 16, No. 5 ( 2019-09), p. 424-430
    Abstract: The aim of this study was to investigate the association between serum carbohydrate antigen 125 concentrations and incident type 2 diabetes mellitus risk in a prospective cohort. Methods: We included 18,983 eligible participants aged 63.1 years derived from the Dongfeng–Tongji cohort at baseline from September 2008 to June 2010, and they were followed until October 2013. Cox proportional-hazards models were used to estimate the hazard ratios and 95% confidence interval of type 2 diabetes mellitus incidence in relation to carbohydrate antigen 125 concentrations. Results: In all, 1594 incident cases of type 2 diabetes mellitus were observed after a median follow-up of 4.6 years. Carbohydrate antigen 125 concentrations were categorized into four groups according to the quartiles of distribution: 〈 1.1, 1.1–5.6, 5.6–10.0 and ⩾10 U/mL. Compared with participants in the lowest quartile, the hazard ratio (95% confidence interval) of type 2 diabetes mellitus was 0.97 (0.81–1.15), 1.23 (1.05–1.45) and 1.48 (1.27–1.74) for quartile 2–quartile 4 of carbohydrate antigen 125 concentrations after adjustment for potential confounders ( p for trend  〈  0.001). With per–standard deviation increase in carbohydrate antigen 125 levels, the hazard ratio of type 2 diabetes mellitus increased 12% (95% confidence interval, 8–16). Conclusion: Findings from this study indicated that serum carbohydrate antigen 125 concentrations were positively correlated with incident type 2 diabetes mellitus risk among a middle-aged and elderly Chinese population.
    Type of Medium: Online Resource
    ISSN: 1479-1641 , 1752-8984
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2250797-8
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