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  • SAGE Publications  (32)
  • 2015-2019  (32)
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  • SAGE Publications  (32)
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  • 2015-2019  (32)
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  • 1
    Online Resource
    Online Resource
    Anatomical Predisposition of the Ankle Joint for Lateral Sprain or Lateral Malleolar Fracture Evaluated by Radiographic Measurements
    SAGE Publications ; 2015
    In:  Foot & Ankle International Vol. 36, No. 1 ( 2015-01), p. 64-69
    Details
    In: Foot & Ankle International, SAGE Publications, Vol. 36, No. 1 ( 2015-01), p. 64-69
    Abstract: Injury mechanism and the amount of force are important factors determining whether a fracture or sprain occurs at the time of an ankle inversion injury. However, the anatomical differences between the ankle fracture and sprain have not been investigated sufficiently. This study was performed to investigate whether an anatomical predisposition of the ankle joint results in a lateral malleolar fracture or lateral ankle sprain. Methods: Two groups of consecutive patients, one with lateral malleolar fracture (274 patients, mean age 49.0 years) and the other with lateral ankle sprain (400 patients, mean age 38.4 years), were evaluated. Ankle radiographs were examined for 7 measures: distal tibial articular surface (DTAS) angle, bimalleolar tilt (BT), medial malleolar relative length (MMRL), lateral malleolar relative length (LMRL), medial malleolar slip angle (MMSA), anterior inclination of tibia (AI), and fibular position (FP). After an interobserver reliability test, the radiographic measurements were compared between the 2 groups. Linear regression analysis was performed to correct for age and sex effects between the groups. Results: The fracture group and the sprain group showed significant differences in BT ( P = .001), MMSA ( P 〈 .001), AI ( P = .023), and FP ( P 〈 .001). In multiple regression analysis, after adjusting for age and sex effects, fracture and sprain groups showed a significant difference in BT ( P = .001), MMRL ( P 〈 .001), MMSA ( P 〈 .001), and FP ( P 〈 .001). Conclusions: The lateral malleolar fracture group tended to show more bony constraint than that of the lateral ankle sprain group. Further 3-dimensional assessment of the bony structure and subsequent biomechanical studies are needed to elucidate the mechanism of injury according to the various types of ankle fractures and ankle sprain. Level of Evidence: Level III, retrospective comparative study.
    Type of Medium: Online Resource
    ISSN: 1071-1007 , 1944-7876
    URL: Article
    DOI: 10.1177/1071100714551019
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2015
    detail.hit.zdb_id: 2129503-7
    detail.hit.zdb_id: 1183283-6
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  • 2
    Online Resource
    Online Resource
    Caveolin-1, Ring finger protein 213 , and endothelial function in Moyamoya disease
    SAGE Publications ; 2016
    In:  International Journal of Stroke Vol. 11, No. 9 ( 2016-12), p. 999-1008
    Details
    In: International Journal of Stroke, SAGE Publications, Vol. 11, No. 9 ( 2016-12), p. 999-1008
    Abstract: Moyamoya disease is a unique cerebrovascular occlusive disease of unknown etiology. Ring finger protein 213 ( RNF213) was identified as a susceptibility gene for Moyamoya disease in East Asian countries. However, the pathogenesis of Moyamoya disease remains unclear. Methods We prospectively analyzed clinical data for 139 patients with Moyamoya disease (108 bilateral Moyamoya disease, 31 unilateral Moyamoya disease), 61 patients with intracranial atherosclerotic stroke, and 68 healthy subjects. We compared the genetic ( RNF213 variant) and protein biomarkers for caveolae (caveolin-1), angiogenesis (vascular endothelial growth factor (VEGF) and receptor (VEGFR2), and antagonizing cytokine (endostatin)) and endothelial dysfunction (asymmetric dimethylarginine (ADMA), and nitric oxide and its metabolites (nitrite and nitrate)) between patients with Moyamoya disease and intracranial atherosclerotic stroke. We then performed path analysis to evaluate whether a certain protein biomarker mediates the association between genes and Moyamoya disease. Results Caveolin-1 level was decreased in patients with Moyamoya disease and markedly decreased in RNF213 variant carriers. Circulating factors such as VEGF and VEGFR2 did not differ among the groups. Markers for endothelial dysfunction were significantly higher in patients with intracranial atherosclerotic stroke but normal in those with Moyamoya disease. Path analysis showed that the presence of the RNF213 variant was associated with caveolin-1 levels that could lead to Moyamoya disease. The level of combined marker of Moyamoya disease (caveolin-1) and intracranial atherosclerotic stroke (ADMA, an endothelial dysfunction marker) predicted Moyamoya disease with good sensitivity and specificity. Conclusion Our results suggest that Moyamoya disease is a caveolae disorder but is not related to endothelial dysfunction or dysregulation of circulating cytokines.
    Type of Medium: Online Resource
    ISSN: 1747-4930 , 1747-4949
    URL: Article
    DOI: 10.1177/1747493016662039
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2016
    detail.hit.zdb_id: 2303728-3
    detail.hit.zdb_id: 2211666-7
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  • 3
    Online Resource
    Online Resource
    RapaNet: A Web Tool for the Co-Expression Analysis of Brassica rapa Genes
    SAGE Publications ; 2017
    In:  Evolutionary Bioinformatics Vol. 13 ( 2017-01-01), p. 117693431771542-
    Details
    In: Evolutionary Bioinformatics, SAGE Publications, Vol. 13 ( 2017-01-01), p. 117693431771542-
    Abstract: Accumulated microarray data are used for assessing gene function by providing statistical values for co-expressed genes; however, only a limited number of Web tools are available for analyzing the co-expression of genes of Brassica rapa. We have developed a Web tool called RapaNet ( http://bioinfo.mju.ac.kr/arraynet/brassica300k/query/ ), which is based on a data set of 143 B rapa microarrays compiled from various organs and at different developmental stages during exposure to biotic or abiotic stress. RapaNet visualizes correlated gene expression information via correlational networks and phylogenetic trees using Pearson correlation coefficient ( r). In addition, RapaNet provides hierarchical clustering diagrams, scatterplots of log ratio intensities, related pathway maps, and cis-element lists of promoter regions. To ascertain the functionality of RapaNet, the correlated genes encoding ribosomal protein (L7Ae), photosystem II protein D1 (psbA), and cytochrome P450 monooxygenase in glucosinolate biosynthesis (CYP79F1) were retrieved from RapaNet and compared with their Arabidopsis homologues. An analysis of the co-expressed genes revealed their shared and unique features.
    Type of Medium: Online Resource
    ISSN: 1176-9343 , 1176-9343
    URL: Article
    DOI: 10.1177/1176934317715421
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2017
    detail.hit.zdb_id: 2227610-5
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  • 4
    Online Resource
    Online Resource
    Experimental study on dynamic load measurement of a tilting mechanism of a railway vehicle using two hydraulic cylinders
    SAGE Publications ; 2017
    In:  Proceedings of the Institution of Mechanical Engineers, Part F: Journal of Rail and Rapid Transit Vol. 231, No. 3 ( 2017-03), p. 370-378
    Details
    In: Proceedings of the Institution of Mechanical Engineers, Part F: Journal of Rail and Rapid Transit, SAGE Publications, Vol. 231, No. 3 ( 2017-03), p. 370-378
    Abstract: A tilting train is primarily designed to achieve increased speed in a curved section without causing discomfort to passengers. Ensuring the safety of the tilting control system is one of the most important factors in such a train. This paper presents the development of a hydraulic tilting system that can measure the force in real time to find the cause of overcurrent occurring often in an actuator of a Korean tilting train. To smoothly realize tilting motion of the Korean tiling train using hydraulic actuators, the developed hydraulic tilting mechanism was designed such that synchronization control of two hydraulic cylinders installed in opposite directions was possible; furthermore, a cooling system was developed to ensure a test environment with an appropriate temperature. The actual force acting on the two hydraulic cylinders was measured and analyzed for various tilting speed of the Korean tilting train. The experimental results show that the hydraulic tilting actuator system developed for the Korean tilting train is valid. Furthermore, it is shown that two actuator loads are detected successfully acting on the hydraulic tilting system.
    Type of Medium: Online Resource
    ISSN: 0954-4097 , 2041-3017
    URL: Article
    DOI: 10.1177/0954409715627841
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2017
    detail.hit.zdb_id: 2024901-9
    detail.hit.zdb_id: 1015041-9
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  • 5
    Online Resource
    Online Resource
    A randomized comparison of energy consumption when using different canes, inpatients after stroke
    SAGE Publications ; 2015
    In:  Clinical Rehabilitation Vol. 29, No. 2 ( 2015-02), p. 129-134
    Details
    In: Clinical Rehabilitation, SAGE Publications, Vol. 29, No. 2 ( 2015-02), p. 129-134
    Abstract: To investigate the differences in oxygen consumption associated with gait in hemiplegic patients according to the type of cane they use. Design: A randomized crossover design. Setting: University hospital-based rehabilitation center, Korea. Subjects: Thirty consecutive patients (mean ± SD age, 56.3 ± 3.2 years) with chronic stroke, 17 (56.7%) males and 13 (43.3%) females. Interventions: At approximately the same time of day for three consecutive days, each participant completed a walk with one of three randomly assigned types of canes: a single-point cane, a quad cane, and a hemi-walker. Main outcome measure: Energy expenditure (O2 rate, mL/kg/min), energy cost (O2 cost, mL/kg/m), and heart rate (HR) via a portable gas analyzer, a 10-meter walk test (10MWT), and a 6-minute walk test (6MWT). Results: Energy expenditure, gait endurance, and gait velocity for a single-point cane were higher ( p 〈 0.001 or p=0.005) than for any other type of cane. Energy cost (0.5 ± 0.2 mL/kg/m vs. 0.6 ± 0.2 mL/kg/m vs. 0.6 ± 0.2 ml/kg/m, respectively, p=0.001) was lower for the single-point cane, except for HR ( p ≥ 0.05) after the Bonferroni correction (0.05/5=0.01). Conclusions: A single-point cane requires less oxygen use at a given speed, or permits greater speed for the same oxygen consumption.
    Type of Medium: Online Resource
    ISSN: 0269-2155 , 1477-0873
    URL: Article
    DOI: 10.1177/0269215514543932
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2015
    detail.hit.zdb_id: 639276-3
    detail.hit.zdb_id: 2028323-4
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  • 6
    Online Resource
    Online Resource
    Contrast-enhanced MR cholangiography with Gd-EOB-DTPA for preoperative biliary mapping: correlation with intraoperative cholangiography
    SAGE Publications ; 2015
    In:  Acta Radiologica Vol. 56, No. 7 ( 2015-07), p. 773-781
    Details
    In: Acta Radiologica, SAGE Publications, Vol. 56, No. 7 ( 2015-07), p. 773-781
    Abstract: Gd-EOB-DTPA-enhanced magnetic resonance (MR) could be used for preoperative evaluation of bile duct anatomy in addition to conventional information of focal hepatic lesions. Purpose To evaluate accuracy of contrast-enhanced MR cholangiography (CE MRC) reconstructed from Gd-EOB-DTPA-enhanced MR images for depicting biliary anatomy with intraoperative cholangiography. Material and Methods We retrospectively identified 71 patients who underwent both preoperative Gd-EOB-DTPA-enhanced MR imaging (MRI) and intraoperative cholangiography for hepatic resections. Two readers independently analyzed biliary anatomy using CE MRC reconstructed from transverse and coronal images separately in 4 weeks. The accuracy and diagnostic confidence were evaluated in correlation with intraoperative cholangiography. The accuracy and confidence score (3-point scale) were compared on CE MRCs from transverse versus coronal images. Results CE MRCs correctly depicted biliary anatomy in 91.5% and 88.7% with coronal images and in 81.7% and 73.2% with transverse images for readers 1 and 2, respectively. CE MRCs from coronal images tended to show greater accuracy ( P = 0.12 and 0.01, for readers 1 and 2) and higher confidence score ( P = 0.11 and P = 0.04, for readers 1 and 2) than those from transverse images. Conclusion Accurate preoperative biliary mapping can be achieved on CE MRC reconstructed from Gd-EOB-DTPA-enhanced MR images. The diagnostic performance was better on CE MRC reconstructed from coronal than those from transverse images.
    Type of Medium: Online Resource
    ISSN: 0284-1851 , 1600-0455
    URL: Article
    DOI: 10.1177/0284185114542298
    RVK:
    XA 10000
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2015
    detail.hit.zdb_id: 105-3
    detail.hit.zdb_id: 2024579-8
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  • 7
    Online Resource
    Online Resource
    Growth rate of serous pancreatic neoplasms in vivo: a retrospective, observational study
    SAGE Publications ; 2019
    In:  Acta Radiologica Vol. 60, No. 4 ( 2019-04), p. 433-440
    Details
    In: Acta Radiologica, SAGE Publications, Vol. 60, No. 4 ( 2019-04), p. 433-440
    Abstract: Determining the growth rate of pancreatic cystic lesions on follow-up imaging is important in managing patients with these lesions. However, the growth rates of serous pancreatic neoplasms (SPNs) have been reported to vary among studies. Purpose To determine the in vivo growth rate of SPNs. Material and Methods This retrospective, single-institutional study included patients diagnosed with SPNs during 2006–2015. The diagnosis of SPNs was based on the results of surgery, endoscopic ultrasonography (EUS)-guided fine needle aspiration (FNA) or core needle biopsy (CNB), or typical radiologic features of SPN. A linear mixed-effects model was utilized to determine whether the diagnostic intervention was associated with tumor growth rate in all patients. The in vivo growth rate of SPNs was estimated from patients without or before diagnostic intervention. SPN growth rates were compared before and after diagnostic intervention. Results SPN growth rates in the overall patient cohort (n = 304) differed significantly between patients who did and did not undergo diagnostic interventions. The in vivo SPN growth rate in 204 patients without or before diagnostic intervention was 1.9 mm/year (95% confidence interval [CI] = 1.6–2.2). In the 130 patients who underwent diagnostic intervention, the SPN growth rate was significantly greater before than after diagnostic intervention (1.8 vs. 0.2 mm/year). Conclusions In the absence of diagnostic intervention, the in vivo growth rate of SPNs was 1.9 mm/year (95% CI = 1.6–2.2). EUS-guided FNA or CNB may affect the growth rate of SPNs.
    Type of Medium: Online Resource
    ISSN: 0284-1851 , 1600-0455
    URL: Article
    DOI: 10.1177/0284185118787350
    RVK:
    XA 10000
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 105-3
    detail.hit.zdb_id: 2024579-8
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  • 8
    Online Resource
    Online Resource
    Triple rule-out CT angiography protocol with restricting field of view for detection of pulmonary thromboembolism and aortic dissection in emergency department patients: simulation of modified CT protocol for reducing radiation dose
    SAGE Publications ; 2017
    In:  Acta Radiologica Vol. 58, No. 5 ( 2017-05), p. 521-527
    Details
    In: Acta Radiologica, SAGE Publications, Vol. 58, No. 5 ( 2017-05), p. 521-527
    Abstract: Triple rule-out computed tomography (TRO CT) is a CT protocol designed to simultaneously evaluate the coronary, aorta, and pulmonary arteries. Purpose To evaluate potential diagnostic performance of TRO CT with restricted volume coverage for detection of pulmonary thromboembolism (PTE) and aortic dissection (AD). Material and Methods This study included 1224 consecutive patients with acute chest pain who visited the emergency department and underwent TRO CT using a 128-slice dual-source CT. Image data were reconstructed according to the display field of view (DFOV) of coronary CT angiography (CCTA) and TRO CT protocols in each patient. The presence of PTE and AD was evaluated by independent observers in each DFOV. The radiation dose was calculated to evaluate the potential benefits by restricting z-axis coverage to cardiac scan range instead of the whole thorax. Results Among all patients, 22 cases with PTE (1.9%) and nine cases with AD (0.8%) were found. Except for one PTE case, all cases were detected on both DFOV of TRO CT and CCTA. Mean effective dose for evaluation of entire thorax and cardiac scan coverage were 5.9 ± 1.1 mSv and 3.5 ± 0.7 mSv, respectively. Conclusion Isolated PTE and AD outside the CCTA DFOV rarely occur. Therefore, modified TRO CT protocol using cardiac scan coverage can be adopted to detect PTE and AD with reduced radiation dose.
    Type of Medium: Online Resource
    ISSN: 0284-1851 , 1600-0455
    URL: Article
    DOI: 10.1177/0284185116663044
    RVK:
    XA 10000
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2017
    detail.hit.zdb_id: 105-3
    detail.hit.zdb_id: 2024579-8
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  • 9
    Online Resource
    Online Resource
    Association Between Lower Urinary Tract Symptoms and Falls in Adults Males: Based on the Korean Community Health Survey
    SAGE Publications ; 2019
    In:  Asia Pacific Journal of Public Health Vol. 31, No. 7 ( 2019-10), p. 643-651
    Details
    In: Asia Pacific Journal of Public Health, SAGE Publications, Vol. 31, No. 7 ( 2019-10), p. 643-651
    Abstract: This study aimed to investigate the correlation between lower urinary tract symptoms (LUTSs) and falls considering places where falls can occur in adult males. We analyzed 101 862 males in the 2011 Korean Community Health Survey. LUTSs were assessed using the International Prostate Symptom Score system. The rate of total and indoor falls significantly increased with the LUTS severity, respectively. After adjusting for age and other confounding variables, the odds ratios (ORs) for total falls were significantly high for the mild (OR = 1.63, 95% confidence interval [CI] = 1.54-1.71), moderate (OR = 2.35, 95% CI = 2.16-2.56), and severe groups (OR = 2.83, 95% CI = 2.49-3.22), relative to the normal group. Indoor fall experience was the same for the mild (OR = 1.56, 95% CI = 1.36-1.79), moderate (OR = 2.37, 95% CI = 1.97-2.85), and severe groups (OR = 3.77, 95% CI = 3.00-4.72). Nocturia, hesitancy, and urgency were significantly associated with indoor falls. The association between falls and the degree of LUTS was observed in both the young and the elderly. Therefore, further studies are needed to determine the effects of treatment of LUTS on the risk of falls and the effectiveness of the fall prevention program.
    Type of Medium: Online Resource
    ISSN: 1010-5395 , 1941-2479
    URL: Article
    DOI: 10.1177/1010539519878361
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2394975-2
    detail.hit.zdb_id: 1025444-4
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  • 10
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    Online Resource
    Xanthii Fructus inhibits allergic response in the ovalbumin-sensitized mouse allergic rhinitis model
    SAGE Publications ; 2015
    In:  Pharmacognosy Magazine Vol. 11, No. 44 ( 2015), p. 352-
    Details
    In: Pharmacognosy Magazine, SAGE Publications, Vol. 11, No. 44 ( 2015), p. 352-
    Type of Medium: Online Resource
    ISSN: 0973-1296
    URL: Article
    DOI: 10.4103/0973-1296.166058
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2015
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