In:
PLOS ONE, Public Library of Science (PLoS), Vol. 18, No. 4 ( 2023-4-21), p. e0284837-
Abstract:
Eight workers involved in packing cross-linked water-soluble acrylic acid polymer, an organic substance, developed pulmonary fibrosis, and the upper lobe was the most affected. The dust concentration in the polymer packing workstation was measured. Chest computed tomography (CT) was obtained for 82 individuals, including the 8 workers mentioned above. Three workers were histopathologically examined. In six of these eight workers, central pulmonary fibrosis and secondary bulla formation caused pneumothorax. Histopathologically, multiple centrilobular fibrotic foci were observed. Chest CT revealed centrilobular nodular opacity and interlobular septal thickening, suggesting early lesions in the workers because the dust concentration was remarkably high. Although the pathogenesis of the disease is unclear, we reported the occurrence of pulmonary fibrosis caused by the exposure to cross-linked water-soluble acrylic acid polymers in humans as it has not been reported earlier.
Type of Medium:
Online Resource
ISSN:
1932-6203
DOI:
10.1371/journal.pone.0284837
DOI:
10.1371/journal.pone.0284837.g001
DOI:
10.1371/journal.pone.0284837.g002
DOI:
10.1371/journal.pone.0284837.g003
DOI:
10.1371/journal.pone.0284837.g004
DOI:
10.1371/journal.pone.0284837.g005
DOI:
10.1371/journal.pone.0284837.g006
DOI:
10.1371/journal.pone.0284837.g007
DOI:
10.1371/journal.pone.0284837.g008
DOI:
10.1371/journal.pone.0284837.g009
DOI:
10.1371/journal.pone.0284837.g010
DOI:
10.1371/journal.pone.0284837.g011
DOI:
10.1371/journal.pone.0284837.g012
DOI:
10.1371/journal.pone.0284837.g013
DOI:
10.1371/journal.pone.0284837.g014
DOI:
10.1371/journal.pone.0284837.t001
DOI:
10.1371/journal.pone.0284837.t002
DOI:
10.1371/journal.pone.0284837.s001
DOI:
10.1371/journal.pone.0284837.r001
DOI:
10.1371/journal.pone.0284837.r002
DOI:
10.1371/journal.pone.0284837.r003
DOI:
10.1371/journal.pone.0284837.r004
DOI:
10.1371/journal.pone.0284837.r005
DOI:
10.1371/journal.pone.0284837.r006
Language:
English
Publisher:
Public Library of Science (PLoS)
Publication Date:
2023
detail.hit.zdb_id:
2267670-3
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