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  • Medip Academy  (2)
  • 2015-2019  (2)
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  • Medip Academy  (2)
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  • 2015-2019  (2)
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  • 1
    Online Resource
    Online Resource
    Medip Academy ; 2017
    In:  International Journal of Basic & Clinical Pharmacology Vol. 6, No. 12 ( 2017-11-23), p. 2853-
    In: International Journal of Basic & Clinical Pharmacology, Medip Academy, Vol. 6, No. 12 ( 2017-11-23), p. 2853-
    Abstract: Background: Inflammation is complex biological response of body tissues to foreign particles or pathogens. However, adverse effects of anti-inflammatory drugs, necessitate the search for a novel compound from herbal origin. Beta vulgaris rubra or red beetroot, a vegetable plant, is known to possess various beneficial effects. Present study aimed to evaluate the anti inflammatory effect of beet roots in animal models.Methods: Carrageenan-induced and Complete Freund’s adjuvant-induced rat paw edema model were used to assess the acute and chronic anti- inflammatory potential of the Beetroot as compared to standard drug, Diclofenac Sodium.Results: Oral administration of Beetroot extract showed carrageenan-induced rat paw edema inhibition by 26.9%, 34.6% and 50% for beetroot 100mg/Kg, 200mg/Kg and 400mg/Kg, respectively, at the end of four hours. In vivo results noted that percentage inhibition of paw volume and ankle diameter of the Complete Freund’s adjuvant-induced rats were significantly higher for the groups consuming 100 and 200mg/Kg Beetroot extracts. Paw volume of the rats in these two groups reduced by 35% and 30% respectively as compared to the control.Conclusions: Thus, beetroot was found to possess anti-inflammatory property in animals. Further investigations are essential to validate the bioactive components responsible for this property.
    Type of Medium: Online Resource
    ISSN: 2279-0780 , 2319-2003
    Language: Unknown
    Publisher: Medip Academy
    Publication Date: 2017
    detail.hit.zdb_id: 2681376-2
    SSG: 15,3
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  • 2
    Online Resource
    Online Resource
    Medip Academy ; 2016
    In:  International Surgery Journal Vol. 4, No. 1 ( 2016-12-13), p. 270-
    In: International Surgery Journal, Medip Academy, Vol. 4, No. 1 ( 2016-12-13), p. 270-
    Abstract: Background:Urinary tract obstruction may occur due to various causes at various levels. Proximal drainage implies drainage of the urinary tract proximal to the site of obstruction. This may be unilateral or bilateral and may be classified as follows: Renal- nephrostomy, pelvic-pyelostomy, ureteral-ureterostomy, vesical-cystostomy and urethral- urethrostomy. The aim of the present work would be to analyse the cases needed such drainage procedure in six months period in a tertiary care teaching hospital, Kolkata, India.Methods: Proximal drainage operations done in series of 35 cases were standard nephrostomy, U-tube nephrostomy, percutaneous needle nephrostomy, end cutaneous ureterostomy, T-tube ureterostomy and suprapubic cystostomy. In 4 cases the drainage operations were done as emergency and lifesaving procedure. Seven drainage operations were done for permanent diversion of urine, 22 as preparatory to subsequent corrective or palliative surgery and 8 as adjuvant with corrective surgery. Clinical findings, post-operative complaints and results of investigations were noted and both pre and post-operative findings were compared to assess the ultimate results of the surgical treatment.Results:Out of 9 cases of nephrostomy, 4 cases (44.44%) showed good result, 4 cases (44.44%) showed fair result and 1 case (11.11%) showed bad result. In 21 cases of T-tube ureterostomy, 15 cases (71.42%) showed good result, 3 cases (14.28%) showed fair result and 3 cases (14.28%) showed bad result. Out of the 6 cases of cutaneous ureterostomy, 4 cases (66.66%) showed good result, 1 cases (16.66%) showed fair result and 1 case (16.66%) showed bad result. The case had bad result (case no. 3) was a case of urinary tuberculosis with ureteric stricture at the lower third with hydroureteronephrosis and poorly functioning kidney on the other side. Out of the 3 cases of suprapubic cystostomy, 1 case showed good result and 2 cases showed fair result.  Conclusions:Drainage operation was done as preparatory to subsequent corrective or palliative surgery in majority of the cases. Proximal drainage helps controlling infection, normalizing blood biochemistry, regression of back pressure changes, in a word improving renal function. Proximal drainage of urine should be done before irreversible damage to the renal parenchyma occurs.
    Type of Medium: Online Resource
    ISSN: 2349-2902 , 2349-3305
    Language: Unknown
    Publisher: Medip Academy
    Publication Date: 2016
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