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  • MDPI AG  (432)
  • 2015-2019  (432)
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  • MDPI AG  (432)
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  • 2015-2019  (432)
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  • 1
    Online Resource
    Online Resource
    Photocatalytic Performance of SiO2/CNOs/TiO2 to Accelerate the Degradation of Rhodamine B under Visible Light
    MDPI AG ; 2019
    In:  Nanomaterials Vol. 9, No. 12 ( 2019-11-22), p. 1671-
    Details
    In: Nanomaterials, MDPI AG, Vol. 9, No. 12 ( 2019-11-22), p. 1671-
    Abstract: A silicon dioxide/carbon nano onions/titanium dioxide (SiO2/CNOs/TiO2) composite was synthesized by a simple sol-gel method and characterized by the methods of X-ray diffraction (XRD), scanning electronic microscope (SEM), X-ray photoelectron spectroscopy (XPS), Brunauer–Emmett–Teller (BET), Fourier transform infrared (FTIR), thermogravimetric analysis (TG), differential scanning calorimeter (DSC) and UV-Vis diffuse reflectance spectra (UV-Vis DRS). In this work, the photocatalytic activity of the SiO2/CNOs/TiO2 photocatalyst was assessed by testing the degradation rate of Rhodamine B (RhB) under visible light. The results indicated that the samples exhibited the best photocatalytic activity when the composite consisted of 3% CNOs and the optimum dosage of SiO2/CNOs/TiO2(3%) was 1.5 g/L as evidenced by the highest RhB degradation rate (96%). The SiO2/CNOs/TiO2 composite greatly improved the quantum efficiency of TiO2. This work provides a new option for the modification of subsequent nanocomposite oxide nanoparticles.
    Type of Medium: Online Resource
    ISSN: 2079-4991
    URL: Article
    DOI: 10.3390/nano9121671
    Language: English
    Publisher: MDPI AG
    Publication Date: 2019
    detail.hit.zdb_id: 2662255-5
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  • 2
    Online Resource
    Online Resource
    Hierarchical Core/Shell Structured Ag@Ni(OH)2 Nanospheres as Binder-Free Electrodes for High Performance Supercapacitors
    MDPI AG ; 2019
    In:  Crystals Vol. 9, No. 2 ( 2019-02-24), p. 118-
    Details
    In: Crystals, MDPI AG, Vol. 9, No. 2 ( 2019-02-24), p. 118-
    Abstract: Hierarchical Ag@Ni(OH)2 nanospheres were achieved directly on copper foam substrate through a convenient two-step process. Ag nanoflowers were formed on copper substrate by galvanic replacement technology between AgNO3 and copper foam followed by electrodeposition of a layer of Ni(OH)2. Ag nanostructures as cores not only dominated the final morphology of the composites, but also improved the electrical conductivity, increased the specific surface area of the active electrode material, and even directly participated in the electrochemical reactions. The resulted Ag@Ni(OH)2 nanospheres could be directly used as high-performance binder-free electrodes and exhibited enhanced electrochemical performance with a high specific capacitance of 1.864 F cm−2 and long cycling lifespans of 90.43% capacity retaining after 3000 cycles.
    Type of Medium: Online Resource
    ISSN: 2073-4352
    URL: Article
    DOI: 10.3390/cryst9020118
    Language: English
    Publisher: MDPI AG
    Publication Date: 2019
    detail.hit.zdb_id: 2661516-2
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  • 3
    Online Resource
    Online Resource
    In Situ Construction of Ag/Ni(OH)2 Composite Electrode by Combining Electroless Deposition Technology with Electrodeposition
    MDPI AG ; 2019
    In:  Metals Vol. 9, No. 8 ( 2019-07-25), p. 826-
    Details
    In: Metals, MDPI AG, Vol. 9, No. 8 ( 2019-07-25), p. 826-
    Abstract: The Ag/Ni(OH)2 composite electrode has been designed and in situ constructed on a copper substrate by combining electroless deposition technology with electrodeposition. The products can be directly used as a high performance binder free electrode. The synergistic effect between the Ag nanocubes (AgNCs) as backbones and the deposited Ni(OH)2 as the shell can significantly improve the electrochemical properties of the composite electrode. Moreover, this in situ growth strategy forms a strong bonding force of active materials to the substrate, which can improve the cycling performance and lower the equivalent series resistance. The Ag/Ni(OH)2 composite electrode exhibits enhanced electrochemical properties with a high specific capacitance of 3.704 F cm−2, coulombic efficiency of 88.3% and long-term cyclic stability.
    Type of Medium: Online Resource
    ISSN: 2075-4701
    URL: Article
    DOI: 10.3390/met9080826
    Language: English
    Publisher: MDPI AG
    Publication Date: 2019
    detail.hit.zdb_id: 2662252-X
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  • 4
    Online Resource
    Online Resource
    Molecular and Cellular Mechanisms of Melatonin in Osteosarcoma
    MDPI AG ; 2019
    In:  Cells Vol. 8, No. 12 ( 2019-12-12), p. 1618-
    Details
    In: Cells, MDPI AG, Vol. 8, No. 12 ( 2019-12-12), p. 1618-
    Abstract: Osteosarcoma, the most common primary bone malignancy, occurs most frequently in adolescents with a peak of incidence at 11–15 years. Melatonin, an indole amine hormone, shows a wide range of anticancer activities. The decrease in melatonin levels simultaneously concurs with the increase in bone growth and the peak age distribution of osteosarcoma during puberty, so melatonin has been utilized as an adjunct to chemotherapy to improve the quality of life and clinical outcomes. While a large amount of research has been conducted to understand the complex pleiotropic functions and the molecular and cellular actions elicited by melatonin in various types of cancers, a few review reports have focused on osteosarcoma. Herein, we summarized the anti-osteosarcoma effects of melatonin and its underlying molecular mechanisms to illustrate the known significance of melatonin in osteosarcoma and to address cellular signaling pathways of melatonin in vitro and in animal models. Even in the same kind of osteosarcoma, melatonin has been sparingly investigated to counteract tumor growth, apoptosis, and metastasis through different mechanisms, depending on different cell lines. We highlighted the underlying mechanism of anti-osteosarcoma properties evoked by melatonin, including antioxidant activity, anti-proliferation, induction of apoptosis, and the inhibition of invasion and metastasis. Moreover, we discussed the drug synergy effects of the role of melatonin involved and the method to fortify the anti-cancer effects on osteosarcoma. As a potential therapeutic agent, melatonin is safe for children and adolescents and is a promising candidate for an adjuvant by reinforcing the therapeutic effects and abolishing the unwanted consequences of chemotherapies.
    Type of Medium: Online Resource
    ISSN: 2073-4409
    URL: Article
    DOI: 10.3390/cells8121618
    Language: English
    Publisher: MDPI AG
    Publication Date: 2019
    detail.hit.zdb_id: 2661518-6
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  • 5
    Online Resource
    Online Resource
    The Effect of Chinese Herbal Medicine Formula mKG on Allergic Asthma by Regulating Lung and Plasma Metabolic Alternations
    MDPI AG ; 2017
    In:  International Journal of Molecular Sciences Vol. 18, No. 3 ( 2017-03-10), p. 602-
    Details
    In: International Journal of Molecular Sciences, MDPI AG, Vol. 18, No. 3 ( 2017-03-10), p. 602-
    Abstract: Asthma is a chronic inflammatory disorder of the airway and is characterized by airway remodeling, hyperresponsiveness, and shortness of breath. Modified Kushen Gancao Formula (mKG), derived from traditional Chinese herbal medicines (TCM), has been demonstrated to have good therapeutic effects on experimental allergic asthma. However, its anti-asthma mechanism remains currently unknown. In the present work, metabolomics studies of biochemical changes in the lung tissue and plasma of ovalbumin (OVA)-induced allergic asthma mice with mKG treatment were performed using ultra high-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (UPLC-Q-TOF/MS). Partial least squares–discriminate analysis (PLS−DA) indicated that the metabolic perturbation induced by OVA was reduced after mKG treatment. A total of twenty-four metabolites involved in seven metabolic pathways were identified as potential biomarkers in the development of allergic asthma. Among them, myristic acid (L3 or P2), sphinganine (L6 or P4), and lysoPC(15:0) (L12 or P16) were detected both in lung tissue and plasma. Additionally, l-acetylcarnitine (L1), thromboxane B2 (L2), 10-HDoHE (L10), and 5-HETE (L11) were first reported to be potential biomarkers associated with allergic asthma. The treatment of mKG mediated all of those potential biomarkers except lysoPC(15:0) (P16). The anti-asthma mechanism of mKG can be achieved through the comprehensive regulation of multiple perturbed biomarkers and metabolic pathways.
    Type of Medium: Online Resource
    ISSN: 1422-0067
    URL: Article
    DOI: 10.3390/ijms18030602
    Language: English
    Publisher: MDPI AG
    Publication Date: 2017
    detail.hit.zdb_id: 2019364-6
    SSG: 12
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  • 6
    Online Resource
    Online Resource
    The Effect of the Anisotropy of Single Crystal Silicon on the Frequency Split of Vibrating Ring Gyroscopes
    MDPI AG ; 2019
    In:  Micromachines Vol. 10, No. 2 ( 2019-02-14), p. 126-
    Details
    In: Micromachines, MDPI AG, Vol. 10, No. 2 ( 2019-02-14), p. 126-
    Abstract: This paper analyzes the effect of the anisotropy of single crystal silicon on the frequency split of the vibrating ring gyroscope, operated in the n = 2 wineglass mode. Firstly, the elastic properties including elastic matrices and orthotropic elasticity values of (100) and (111) silicon wafers were calculated using the direction cosines of transformed coordinate systems. The (111) wafer was found to be in-plane isotropic. Then, the frequency splits of the n = 2 mode ring gyroscopes of two wafers were simulated using the calculated elastic properties. The simulation results show that the frequency split of the (100) ring gyroscope is far larger than that of the (111) ring gyroscope. Finally, experimental verifications were carried out on the micro-gyroscopes fabricated using deep dry silicon on glass technology. The experimental results are sufficiently in agreement with those of the simulation. Although the single crystal silicon is anisotropic, all the results show that compared with the (100) ring gyroscope, the frequency split of the ring gyroscope fabricated using the (111) wafer is less affected by the crystal direction, which demonstrates that the (111) wafer is more suitable for use in silicon ring gyroscopes as it is possible to get a lower frequency split.
    Type of Medium: Online Resource
    ISSN: 2072-666X
    URL: Article
    DOI: 10.3390/mi10020126
    Language: English
    Publisher: MDPI AG
    Publication Date: 2019
    detail.hit.zdb_id: 2620864-7
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  • 7
    Online Resource
    Online Resource
    A Case Study on the Application of the Steel Tube Slab Structure in Construction of a Subway Station
    MDPI AG ; 2018
    In:  Applied Sciences Vol. 8, No. 9 ( 2018-08-23), p. 1437-
    Details
    In: Applied Sciences, MDPI AG, Vol. 8, No. 9 ( 2018-08-23), p. 1437-
    Abstract: It is an effective approach to use Steel Tube Slab (STS) structure combined with the Pile-Beam-Arch (PBA) method to construct a large-space underground station. Traditional construction methods cannot meet the requirement of construction because of the complicated soil layers and high building densities in urban areas. The STS method can effectively increase the rigidity of the supporting system by using steel tubes. Firstly, the stress of bolts and steel tubes are investigated in the construction process based on the field monitoring data. Subsequently, FLAC3D is used to establish a three-dimensional model, which is verified based on the in-situ monitoring data; the effect of excavation process on ground settlement, deformation of STS structure and bridge pile are studied by numerical results. Moreover, the key parameters such as welding of flanges and the step length are studied. The results show that the stress of the steel tubes and flanges does not exceed the designed strength during the construction process. Based on the numerical simulation data, it is indicated that the STS structure can be a very effective and dependable measure in controlling and reducing the surface settlement and the existing adjacent buildings. The numerical results can be used to guide the later construction.
    Type of Medium: Online Resource
    ISSN: 2076-3417
    URL: Article
    DOI: 10.3390/app8091437
    Language: English
    Publisher: MDPI AG
    Publication Date: 2018
    detail.hit.zdb_id: 2704225-X
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  • 8
    Online Resource
    Online Resource
    Extraction, Structure, and Pharmacological Activities of Astragalus Polysaccharides
    MDPI AG ; 2018
    In:  Applied Sciences Vol. 9, No. 1 ( 2018-12-31), p. 122-
    Details
    In: Applied Sciences, MDPI AG, Vol. 9, No. 1 ( 2018-12-31), p. 122-
    Abstract: The Astragalus polysaccharides (APS) are important bioactive components of Astragali Radix, the dry root of Astragalus membranaceus, which has been used in traditional Chinese medicine. In this review, the extraction conditions and extraction rates of APS are first compared for water, microwave-assisted, ultrasonic wave, and enzymatic hydrolysis extraction methods. Some studies have also shown that different methods can be combined to improve the extraction rate of APS. Subsequently, the chemical composition and structure of APS are discussed, as related to the extraction and purification method. Most studies have shown that APS is mainly composed of glucose, in addition to rhamnose, galactose, arabinose, xylose, mannose, glucuronic acid, and galacturonic acid. We also reviewed studies on the modification of APS using chemical methods, including sulfated modification using the chlorosulfonic acid–pyridine method, which is commonly used for chemical modification of APS. Finally, the pharmacological activities and mechanisms of action of APS are summarized, with a special focus on its immunoregulatory, antitumor, anti-inflammatory, and antiviral effects. This review will serve as a valuable resource for the research on APS.
    Type of Medium: Online Resource
    ISSN: 2076-3417
    URL: Article
    DOI: 10.3390/app9010122
    Language: English
    Publisher: MDPI AG
    Publication Date: 2018
    detail.hit.zdb_id: 2704225-X
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  • 9
    Online Resource
    Online Resource
    Estimating Surface Downward Shortwave Radiation over China Based on the Gradient Boosting Decision Tree Method
    MDPI AG ; 2018
    In:  Remote Sensing Vol. 10, No. 2 ( 2018-01-26), p. 185-
    Details
    In: Remote Sensing, MDPI AG, Vol. 10, No. 2 ( 2018-01-26), p. 185-
    Type of Medium: Online Resource
    ISSN: 2072-4292
    URL: Article
    DOI: 10.3390/rs10020185
    Language: English
    Publisher: MDPI AG
    Publication Date: 2018
    detail.hit.zdb_id: 2513863-7
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  • 10
    Online Resource
    Online Resource
    Dietary Patterns Modulate the Risk of Non-Alcoholic Fatty Liver Disease in Chinese Adults
    MDPI AG ; 2015
    In:  Nutrients Vol. 7, No. 6 ( 2015-06-15), p. 4778-4791
    Details
    In: Nutrients, MDPI AG, Vol. 7, No. 6 ( 2015-06-15), p. 4778-4791
    Type of Medium: Online Resource
    ISSN: 2072-6643
    URL: Article
    DOI: 10.3390/nu7064778
    Language: English
    Publisher: MDPI AG
    Publication Date: 2015
    detail.hit.zdb_id: 2518386-2
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