GLORIA

GEOMAR Library Ocean Research Information Access

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    facet.materialart.
    Unknown
    A Fuzzy Neural Network Based on Non-Euclidean Distance Clustering for Quality Index Model in Slashing Process (2015)
    Hindawi
    Details
    Publication Date: 2015-06-11
    Description: The quality index model in slashing process is difficult to build by reason of the outliers and noise data from original data. To the above problem, a fuzzy neural network based on non-Euclidean distance clustering is proposed in which the input space is partitioned into many local regions by the fuzzy clustering based on non-Euclidean distance so that the computation complexity is decreased, and fuzzy rule number is determined by validity function based on both the separation and the compactness among clusterings. Then, the premise parameters and consequent parameters are trained by hybrid learning algorithm. The parameters identification is realized; meanwhile the convergence condition of consequent parameters is obtained by Lyapunov function. Finally, the proposed method is applied to build the quality index model in slashing process in which the experimental data come from the actual slashing process. The experiment results show that the proposed fuzzy neural network for quality index model has lower computation complexity and faster convergence time, comparing with GP-FNN, BPNN, and RBFNN.
    Print ISSN: 1024-123X
    Electronic ISSN: 1563-5147
    Topics: Mathematics , Technology
    Published by Hindawi
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 2
    facet.materialart.
    Unknown
    Effects of TGF-β1 on OPG/RANKL Expression of Cementoblasts and Osteoblasts Are Similar without Stress but Different with Mechanical Compressive Stress (2015)
    Hindawi
    Details
    Publication Date: 2015-01-16
    Description: Introduction. This study aimed to explore the effects of TGF-β1 on regulating activities of cementoblasts and osteoblasts with or without stress. Material and Methods. Human recombinant TGF-β1 was added with different doses. Immunohistochemical test of osteoprotegerin (OPG)/receptor activator of nuclear factor-kappaB ligand (RANKL) and Alizarin Red-S staining were conducted. Mechanical compressive stress was obtained by increasing the pressure of gaseous phase. OPG/RANKL expression was detected in both cells through quantitative real-time PCR. Results. Similar significant differences () existed in OPG/RANKL change with increasing concentration of TGF-β1 without mechanical stress for cementoblasts and osteoblasts. However, under 3 h stress, OPG increased and RANKL decreased significantly () but with similar OPG/RANKL change. Moreover, under 24 h stress, OPG change exhibited no difference (), but RANKL decreased significantly () at 10 and 100 ng/mL TGF-β1 in cementoblasts. In osteoblasts, OPG increased significantly () at 10 and 100 ng/mL, whereas RANKL decreased with statistical difference () at 1 and 10 ng/mL. Conclusions. The effects of TGF-β1 on OPG/RANKL expression of cementoblasts and osteoblasts are similar even without mechanical stress. However, these effects are different under mechanical compressive stress.
    Electronic ISSN: 1537-744X
    Topics: Natural Sciences in General
    Published by Hindawi
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 3
    facet.materialart.
    Unknown
    Macrophage Migration Inhibitory Factor Interacting with Th17 Cells May Be Involved in the Pathogenesis of Autoimmune Damage in Hashimoto’s Thyroiditis (2015)
    Hindawi
    Details
    Publication Date: 2015-03-16
    Description: Purpose. To explore the possible role of MIF and Th17 cells in the thyroid-specific autoimmune damage of Hashimoto’s thyroiditis (HT). Material and Methods. We enrolled 40 HT patients and 30 healthy controls and divided HT patients into euthyroid subset () and subclinical or overt hypothyroidism subset (). The percentages of Th17 cells and expressions of MIF, interleukin 17A (IL-17A) mRNA in PBMCs, as well as serum concentrations of MIF, and IL-17A, and thyroid functions, and thyroid-specific autoantibodies (TPOAb, TgAb) were detected by flow cytometry, real-time RT-PCR, ELISA, and ECLIA in all subjects. Results. MIF mRNA, IL-17A mRNA expressions and Th17 cells percentages, serum MIF, and IL-17A protein levels were all significantly higher in HT patients, even in euthyroid subgroup. Additionally, the differences became more obvious in dysfunction subgroup. Importantly, both MIF levels and Th17 cells percentage were positively correlated with serum TPOAb, TgAb, and thyrotropin (TSH) levels in HT patients. Conclusions. These data suggest that MIF and Th17 cells increased dynamically and positively correlated with the markers of thyroid autoimmune damage, which indicated that interaction between MIF and Th17 cells may participate in the pathogenesis and development of thyroid-specific autoimmunity in HT.
    Print ISSN: 0962-9351
    Electronic ISSN: 1466-1861
    Topics: Medicine
    Published by Hindawi
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...