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  • 1
    Online Resource
    Online Resource
    Oxford :Taylor & Francis Group,
    Keywords: Corpus callosum. ; Brain-Localization of functions. ; Laterality. ; Electronic books.
    Description / Table of Contents: Originally published in 1986, this title demonstrates how popular topics within psychology at the time, such as laterality, hemisphere differences and the psychology of left and right, are central to further progress in understanding the human brain.
    Type of Medium: Online Resource
    Pages: 1 online resource (277 pages)
    Edition: 1st ed.
    ISBN: 9780429954832
    Series Statement: Psychology Library Editions: Neuropsychology Series ; v.2
    DDC: 612.82
    Language: English
    Note: Cover -- Half Title -- Title Page -- Copyright Page -- Contents -- Lists of tables and figures -- Acknowledgments -- Preface: What is the 'brain code'? -- 1 Introduction -- The brain code and the neuron code -- Evolution of the brain - the Vertical' dimension -- Bilateral symmetry - the 'horizontal' dimension -- First steps toward the brain code -- Why is there bilateral asymmetry of function in the human brain? -- What is the right hemisphere doing? -- Summary -- 2 Brain structures involved in interhemispheric communication -- The neocortex -- How the brain sees: retinotopic maps -- The brain's body image: somatotopic maps -- How the brain hears: tonotopic maps -- Two-dimensional mapping -- The brainstem -- The corpus callosum -- Summary -- 3 Functions of the corpus callosum -- Current ideas concerning callosal function -- The topographical excitatory hypothesis -- The diffuse inhibitory hypothesis -- The diffuse excitatory hypothesis -- The topographical inhibitory hypothesis -- Further development of the topographical inhibitory hypothesis -- Approximate bilateral symmetry of the cerebral hemispheres -- Columnar organization of the neocortex -- Homotopic callosal connections -- Callosal inhibition -- Unilateral superiority of one hemisphere for speech -- Cortical surround inhibition -- Bilaterally symmetrical subcortical mechanism of arousal -- Computer simulation of callosal effects -- Summary -- 4 Neuropsychological implications of callosal function -- Normal functions of the corpus callosum in the intact brain -- Indications of callosal functions in abnormal brains -- Unilateral brain damage -- Surgical section of the corpus callosum -- Agenesis of the corpus callosum -- Summary -- 5 Major themes of cerebral laterality -- Language -- Visuospatial functions -- Musical functions -- The Japanese language. , Can other hemispheric dichotomies be related to 'focus-context'? -- Conclusions -- 6 Relevant animal experiments -- Association cortex and the intrahemispheric convergence of sensory pathways -- Mirror-image transfers across the forebrain commissures -- The unilateral engram -- Cerebral dominance in animals -- Binocular depth perception and the role of the corpus callosum -- 7 A theoretical framework for the study of the brain code -- How are natural systems organized? -- The atomic system -- The cellular system -- The animal organism -- The atomic code and the genetic code -- The brain code -- Systemic pathology -- Summary -- 8 Conclusions -- The evolutionary context -- Implications for artificial intelligence -- Final remarks -- Appendix 1 Maps of the cerebral cortex -- Appendix 2 Computer simulations -- References -- Glossary -- Index.
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  • 2
    Online Resource
    Online Resource
    New York, NY :Enslow Publishing, LLC,
    Keywords: Electronic books.
    Description / Table of Contents: Astrophysicist, cosmologist, and AU, Neil deGrasse Tyson has devoted his life to understanding the universe and helping others do the same. He is an activist, an educator, and a television personality. Let his passion for making science fun inspire the scientist in you.
    Type of Medium: Online Resource
    Pages: 1 online resource (26 pages)
    Edition: 1st ed.
    ISBN: 9780766066694
    Series Statement: Exceptional African Americans Series
    DDC: 523.01092 B
    Language: English
    Note: Cover -- Title Page -- Words to Know -- Contents -- Chapter 1: Early Life -- Chapter 2: Student of Science -- Chapter 3: Neil's Job -- Chapter 4: America's Science Teacher -- Timeline -- Learn More -- Index -- Back Cover.
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  • 3
    Publication Date: 2015-07-30
    Description: ABSTRACT Crevasse splays are common geomorphological features in alluvial and deltaic floodplains. Although crevasse splays can develop into full avulsions, thereby transforming large areas of floodbasins, little is known about their sedimentary and geomorphological development at the decadal scale and their avulsion potential. We used aerial photography and lithological cross-sections to reconstruct crevasse-splay formation in the largely unmanaged floodplain of the Saskatchewan River in the Cumberland Marshes (Saskatchewan, Canada). Based on surface geomorphology and subsurface deposits, various stages of crevasse-splay development were described which were linked to both external forcing and internal morphodynamics. Initial splay deposition, following a levee breach during a large flood, occurred as a broad but relatively thin sandy sheet in a down-basin direction in the receiving backswamp area. In a next phase, these primary crevasse-splay deposits blocked local down-basin flow, thereby forcing the crevasse-splay channel in a direction perpendicular to the parent channel and original floodbasin gradient. This created an asymmetrical splay sequence composition, which differs in appearance from more commonly observed dendritic crevasse splays. It is concluded that sedimentation patterns in the splay have been influenced by inherited effects of previously formed deposits. Feedbacks of the original floodbasin gradient and earlier stages of splay formation are suggested as prominent mechanisms in creating the current morphology, orientation, and architecture of its deposits. This article is protected by copyright. All rights reserved.
    Print ISSN: 0197-9337
    Electronic ISSN: 1096-9837
    Topics: Geography , Geosciences
    Published by Wiley-Blackwell
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  • 4
    Publication Date: 2016-07-28
    Description: Vps75 is a histone chaperone that has been historically characterized as homodimer by X-ray crystallography. In this study, we present a crystal structure containing two related tetrameric forms of Vps75 within the crystal lattice. We show Vps75 associates with histones in multiple oligomers. In the presence of equimolar H3–H4 and Vps75, the major species is a reconfigured Vps75 tetramer bound to a histone H3–H4 tetramer. However, in the presence of excess histones, a Vps75 dimer bound to a histone H3–H4 tetramer predominates. We show the Vps75–H3–H4 interaction is compatible with the histone chaperone Asf1 and deduce a structural model of the Vps75–Asf1-H3–H4 (VAH) co-chaperone complex using the Pulsed Electron-electron Double Resonance (PELDOR) technique and cross-linking MS/MS distance restraints. The model provides a molecular basis for the involvement of both Vps75 and Asf1 in Rtt109 catalysed histone H3 K9 acetylation. In the absence of Asf1 this model can be used to generate a complex consisting of a reconfigured Vps75 tetramer bound to a H3–H4 tetramer. This provides a structural explanation for many of the complexes detected biochemically and illustrates the ability of Vps75 to interact with dimeric or tetrameric H3–H4 using the same interaction surface.
    Print ISSN: 0305-1048
    Electronic ISSN: 1362-4962
    Topics: Biology
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  • 5
    Publication Date: 2017-06-01
    Description: BACKGROUND: Deficiency of Suppressor of Fused (SuFu), an intracellular mediator of Hedgehog signaling, in the murine mid-hindbrain disrupts cerebellar morphogenesis and cell differentiation in a manner that is rescued by constitutive expression of GLI3 transcriptional repressor (GLI3R). Here, we determined SuFu functions in cerebellar radial precursors following the stage of mid-hindbrain specification using a Blbp-Cre transgene. RESULTS: SuFu- deficient cerebella were severely dysplastic, and characterized by laminar disorganization, and delayed differentiation of ventricular zone-derived precursors. In vitro analysis of cerebellar precursors isolated from control and mutant mice demonstrated an increased proportion of radial glial precursors versus Tuj1- positive neurons in mutant cultures. Abnormal cell differentiation in SuFu-deficient precursors was rescued by a constitutively expressed GLI3R knock-in allele, albeit with variable penetrance. Using RNA expression analysis in control and SuFu- deficient cerebellar anlage, we identified up-regulation of Fgf15 in mutant tissue. Strikingly, exogenous hFGF19, a mFGF15 ortholog, inhibited neuronal differentiation in cultures of wild-type cerebellar precursors. Moreover, siRNA-mediated knockdown of Fgf15 in SuFu -deficient cerebellar precursors rescued their delayed differentiation to neurons. CONCLUSIONS: Together, our results show that SuFu promotes cerebellar radial precursor differentiation to neurons. SuFu function is mediated in part by GLI3R and down-regulation of Fgf15 expression. This article is protected by copyright. All rights reserved.
    Electronic ISSN: 1097-0177
    Topics: Medicine
    Published by Wiley-Blackwell
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  • 6
    Publication Date: 2018-04-07
    Description: Meeting the growing demand for animal-sourced food, prompted by population growth and increases in average per-capita income in low-income countries, is a major challenge. Yet, it also presents significant potential for agricultural growth, economic development, and reduction of poverty in rural areas. The main constraints to livestock producers taking advantage of growing markets include; lack of forage and feed gaps, communal land tenure, limited access to land and water resources, weak institutions, poor infrastructure and environmental degradation. To improve rural livelihood and food security in smallholder crop-livestock farming systems, concurrent work is required to address issues regarding efficiency of production, risk within systems and development of whole value chain systems. This paper provides a review of several forage based-studies in tropical and non-tropical dry areas of the developing countries. A central tenet of this paper is that forages have an essential ...
    Print ISSN: 1755-1307
    Electronic ISSN: 1755-1315
    Topics: Geography , Geosciences , Physics
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  • 7
    Publication Date: 2018-01-18
    Description: Salinity is widely recognized as a dominant environmental variable in estuarine systems. However, drawing clear causal relationships between salinity and estuarine floral or faunal patterns of abundance, population status, or vigor is often confounded by the great spatial and temporal variation exhibited by salinity. Averages, or other statistics, over monthly, seasonal, or longer periods are often used, but may fail to capture patterns of ecological significance. This study introduces a novel approach to characterize estuarine salinity based on deriving events of specific magnitude and duration from a long-term record; events that are also amenable to analysis of the frequency that they reoccur. With sufficient point data for salinity over the spatial domain of an estuary, these variables can be mapped and contoured to reveal spatial patterns of potential ecological significance. Model-predicted salinity for a large estuary system of the Texas coast was used to develop and test these new techniques. While this system has great variation in salinity, both temporally and spatially, we find that this variability can be characterized into well-defined and reoccurring salinity-based events. Furthermore, the frequency of reoccurrence of those events over a long-term record reveals patterns not captured by more common techniques such as averaging over similar time frames. These novel techniques provide an integrated spatial-temporal approach to salinity pattern portrayal which may be useful for examining short-term (daily–monthly) estuary processes and longer-term (yearly–decadal) limits to estuary species distributions and habitat composition.
    Electronic ISSN: 1541-5856
    Topics: Biology , Geosciences
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  • 8
    Publication Date: 2016-01-08
    Description: Bacterial biological control agents (BCAs) are largely used as live products to control plant pathogens. However, due to variable environmental and ecological factors, live BCAs usually fail to produce desirable results against foliar pathogens. In this study, we investigated the potential of cell-free culture filtrates of 12 different bacterial BCAs isolated from flower beds for controlling foliar diseases caused by Alternaria spp. In vitro studies showed that culture filtrates from two isolates belonging to Bacillus subtilis and Bacillus amyloliquefaciens displayed strong efficacy and potencies against Alternaria spp. The antimicrobial activity of the culture filtrate of these two biological control agents was effective over a wider range of pH (3.0 to 9.0) and was not affected by autoclaving or proteolysis. Comparative liquid chromatography-mass spectrometry (LC-MS) analyses showed that a complex mixture of cyclic lipopeptides, primarily of the fengycin A and fengycin B families, was significantly higher in these two BCAs than inactive Bacillus spp. Interaction studies with mixtures of culture filtrates of these two species revealed additive activity, suggesting that they produce similar products, which was confirmed by LC-tandem MS analyses. In in planta pre- and postinoculation trials, foliar application of culture filtrates of B. subtilis reduced lesion sizes and lesion frequencies caused by Alternaria alternata by 68 to 81%. Taken together, our studies suggest that instead of live bacteria, culture filtrates of B. subtilis and B. amyloliquefaciens can be applied either individually or in combination for controlling foliar diseases caused by Alternaria species.
    Print ISSN: 0099-2240
    Electronic ISSN: 1098-5336
    Topics: Biology
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  • 9
    ISSN: 1520-4804
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of agricultural and food chemistry 19 (1971), S. 140-142 
    ISSN: 1520-5118
    Source: ACS Legacy Archives
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
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