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  • 1
    Electronic Resource
    Electronic Resource
    Contact dermatitis due to the constituents of Hibiscrub (1981)
    Oxford, UK : Blackwell Publishing Ltd
    Contact dermatitis 7 (1981), S. 0 
    Details
    ISSN: 1600-0536
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Two patients who underwent extensive pre-operative skin preparations with Hibiscrub prior to orthopaedic operations developed acute contact dermatitis at the operation site post-operatively, Both were shown to be sensitised to Ammonyx LO, the foaming agent in Hibiscrub, and one also to chlorliexidine diglcomate. The details of two other patients who had reacted similary were reviewed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0536.1981.tb04090.x
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  • 2
    Electronic Resource
    Electronic Resource
    Occupational dermatitis due to 1,2-benzisothiazolin-3-one in the pottery industry (1981)
    Oxford, UK : Blackwell Publishing Ltd
    Contact dermatitis 7 (1981), S. 0 
    Details
    ISSN: 1600-0536
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Three men working as mouldmakers in the pottery industry acquired a contact allergic dermatitis to a releasing oil. All three were shown to he sensitized to the biocide (1,2-benzisothinzolin-3-one) in the oil.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0536.1981.tb04587.x
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  • 3
    Electronic Resource
    Electronic Resource
    COELIAC DISEASE AND HLA: A FAMILY STUDY (1980)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 7 (1980), S. 0 
    Details
    ISSN: 1744-313X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: In a family study of coeliac disease, HLA types in fifty-three patients and their relatives were examined. There are no differences in HLA frequencies between child and adult patients. Comparison with a random series of normal controls shows increases frequencies in patients of HLA-A1 and B8, while the family material shows that there is also an excess of haplotype I-8. The excess of homozygotes is thought not to be a factor in the aetiology. Intrafamilial analysis shows that only B8 is significantly associated with the disorder. It is argued that the HLA association does not indicate a ‘coeliac gene’ but that the B8 allele is a major gene in a polygenic system affecting the disorder.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1744-313X.1980.tb00732.x
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  • 4
    Electronic Resource
    Electronic Resource
    Detection of the action of salicylic acid on the normal stratum corneum (1980)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 103 (1980), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The undoubted clinical usefulness of salicylic acid contrasts markedly with its barely detectable action on normal skin. In this study we have attempted to extend our understanding of the action of salicylic acid by monitoring its effect on the stratum corneum using newly developed techniques for assessing desquamation, as well as using conventional methods for measuring other aspects of epidermal activity.Our findings have succeeded in demonstrating that salicylic acid enhances the shedding of corneocytes and we suggest that this compound in some way decreases corneocyte to corneocyte cohesion.We have confirmed that salicylic acid has no effect on the mitotic activity of the normal epidermis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.1980.tb06590.x
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  • 5
    Electronic Resource
    Electronic Resource
    The major serum proteins of Dipteran larvae (1981)
    Springer
    Cellular and molecular life sciences 37 (1981), S. 103-110 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The major serum proteins of Dipteran larvae present something of an enigma. In many respects they are extremely well suited for studies on gene structure and control, protein chemistry and physiology. Large amounts of these proteins are synthesized by the fat body at specific stages of larval development, much is known about their biochemistry, genetics and evolution and some information is available about the control of their synthesis. There are however doubts as to their function. This article considers what is known about these proteins in Dipterans and other insect groups and relates this information to their evolution and their possible function.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01963174
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  • 6
    Electronic Resource
    Electronic Resource
    An empirical test of biases in the rapid visual technique for species-time censuses of reef fish assemblages (1982)
    Springer
    Marine biology 70 (1982), S. 129-134 
    Details
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract For an assemblage of fishes inhabiting a warm temperate, rock reef near San Diego, California (USA), a series of censuses were made based on frequency of occurrence and standard numerical counts. These data were then compared with a parallel study based on the rapid visual technique (RVT) of Jones and Thompson (1978). Because the RVT ranks abundances according to frequency of encounter and disregards variations in the spatial distributions of different species, the method overemphasizes the importance of widespread albeit rare fishes but under-emphasizes patchy although abundant species. The discussion considers the relative merits of the RVT method for characterizing assemblages of fishes on temperate rock reefs and on tropical coral reefs.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00397676
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  • 7
    Electronic Resource
    Electronic Resource
    Effect of nutritional copper deficiency on adjuvant arthritis and immunocompetence in the rat (1984)
    Springer
    Inflammation research 14 (1984), S. 274-282 
    Details
    ISSN: 1420-908X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Both severe and marginal copper deficiency were produced in male Sprague Dawley rats prior to induction of adjuvant arthritis. Degree of copper deficiency was confirmed by analysis of plasma, liver, and brain samples prior to adjuvant injection. Incidence of adjuvant arthritis was the same in both copper deficient and control animals although the severity was slightly but not statistically less in the former. However, recovery from foot edema was impaired in copper-deficient animals, while marginally copper-deficient animals recovered at the same rate as did controls. Plasma copper concentration increase in response to the injection of adjuvant and the increase was directly related to dietary copper content. Plasma zinc concentration was decreased in arthritic animals and the decrease was inversely correlated to paw edema. Liver copper, zinc, and iron concentrations in arthritic animals remained unchanged or increased slightly in comparison to the corresponding non-injected controls. Copper-deficient rats were immunosuppressed as demonstrated by impaired responsiveness to the T-cell dependent contact sesitizing agent oxazolone and diminshed capacity to respond to the T-cell independent antigen Type III pneumococcal polysaccharide. Although a statistical difference in paw volumes was not found for group of animals fed diets differing in copper content, it is postulated that copper deficiency may alter the severity and kinetics of adjuvant arthritis by impairing aspects of the immune response and the tissue repair processes subsequent to injury.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01966653
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  • 8
    Electronic Resource
    Electronic Resource
    Drosophila larval fat body surfaces (1983)
    Springer
    Development genes and evolution 192 (1983), S. 1-7 
    Details
    ISSN: 1432-041X
    Keywords: Fat body ; Basement membrane ; Ageing ; Transplantation ; Monoclonal antibody
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary The hemocytes oftu-Sz ts melanotic tumor larvae ofDrosophila melanogaster encapsulate heterospecific and surface-modified homospecific tissue implants, but do not encapsulate unmodified homospecific implants (R. Rizki and Rizki 1980). In the present study we usedtu-Sz ts hosts to assay changes in larval fat body surfaces during development. Donor fat bodies from various ages of larvae were accepted (remained unencapsulated) intu-Sz ts hosts whereas fat bodies from donors with everted spiracles and all subsequent stages of development that were tested were rejected (encapsulated). Since the demarcation between acceptance and rejection by thetu-Sz ts blood cells did not coincide with the gross morphological changes that appear in the fat body during metamorphosis (dissolution of the basement membrane and dispersal of the freed fat body cells at pupation), we compared acceptable and nonacceptable fat body surfaces by three other methods. Fat body surface ultrastructure was examined, fat bodies were treated with fluorescein isothiocyanate-conjugated lectins, and fat body surfaces were reacted with a monoclonal antibody specific for basement membrane. These approaches did not uncover fat body surface changes associated with eversion of the anterior spiracles, suggesting that recognition of tissue surface heterogeneities by the insect hemocytes exceeds the resolving power of the other three methods. However, the monoclonal antibody fails to bind to the basement membrane ofD. virilis larvae, whose fat body is always rejected intu-Sz ts hosts. This supports our suggestion that the molecular architecture of the basement membrane may be important in eliciting the encapsulation response.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00848762
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  • 9
    Electronic Resource
    Electronic Resource
    Cytogenetic studies in spontaneous abortuses (1984)
    Springer
    Human genetics 〈Berlin〉 66 (1984), S. 77-84 
    Details
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary In a series of 450 products of conception received for cytogenetic analysis, tissue culture was attempted on 309, and karyotypes were established using banding techniques in 154 singleton specimens. Abnormalities of karyotype were identified in 19%; of these abnormalities, 48% were autosomal trisomies. Gestational age was decreased in the abnormal specimens, and their developmental age was retarded by comparison with their gestational age. Factors contributing to the relatively low incidence of abnormality are examined. The major factor appears to be the clinical interest of collaborating staff, leading to selection, either intentional or unintentional, of particular phenotypes and hence a non-random series. A negative relationship is suggested between frequency of monsomy X and autosomal trisomy, both being associated with maternal age.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00275191
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  • 10
    Electronic Resource
    Electronic Resource
    Satellite association in Down's syndrome (1981)
    Springer
    Human genetics 〈Berlin〉 56 (1981), S. 309-313 
    Details
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The frequency of association of acrocentric chromosomes is examined in 20 Down's syndrome children, their parents, and 60 controls. Chromosome 21 enters into satellite associations most frequently, and chromosome 15 least. The parents of Down's syndrome children do not show any increased tendency for satellite association of chromosome 21 or indeed any other acrocentric.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00274685
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