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  • 1
    Online Resource
    Online Resource
    Cham :Springer International Publishing AG,
    Keywords: Neurosciences. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (180 pages)
    Edition: 1st ed.
    ISBN: 9783319553108
    Series Statement: Intelligent Systems Reference Library ; v.126
    DDC: 006.3
    Language: English
    Note: Intro -- Preface -- Contents -- Acronyms -- 1 Introduction -- 1.1 Background -- 1.2 Spiking Neurons -- 1.2.1 Biological Background -- 1.2.2 Generations of Neuron Models -- 1.2.3 Spiking Neuron Models -- 1.3 Neural Codes -- 1.3.1 Rate Code -- 1.3.2 Temporal Code -- 1.3.3 Temporal Code Versus Rate Code -- 1.4 Cognitive Learning and Memory in the Brain -- 1.4.1 Temporal Learning -- 1.4.2 Cognitive Memory in the Brain -- 1.5 Objectives and Contributions -- 1.6 Outline of the Book -- References -- 2 Rapid Feedforward Computation by Temporal Encoding and Learning with Spiking Neurons -- 2.1 Introduction -- 2.2 The Spiking Neural Network -- 2.3 Single-Spike Temporal Coding -- 2.4 Temporal Learning Rule -- 2.4.1 The Tempotron Rule -- 2.4.2 The ReSuMe Rule -- 2.4.3 The Tempotron-Like ReSuMe Rule -- 2.5 Simulation Results -- 2.5.1 The Data Set and the Classification Problem -- 2.5.2 Encoding Images -- 2.5.3 Choosing Among Temporal Learning Rules -- 2.5.4 The Properties of Tempotron Rule -- 2.5.5 Recognition Performance -- 2.6 Discussion -- 2.6.1 Encoding Benefits from Biology -- 2.6.2 Types of Synapses -- 2.6.3 Schemes of Readout -- 2.6.4 Extension of the Network for Robust Sound Recognition -- 2.7 Conclusion -- References -- 3 A Spike-Timing Based Integrated Model for Pattern Recognition -- 3.1 Introduction -- 3.2 The Integrated Model -- 3.2.1 Neuron Model and General Structure -- 3.2.2 Latency-Phase Encoding -- 3.2.3 Supervised Spike-Timing Based Learning -- 3.3 Numerical Simulations -- 3.3.1 Network Architecture and Encoding of Grayscale Images -- 3.3.2 Learning Performance -- 3.3.3 Generalization Capability -- 3.3.4 Parameters Evaluation -- 3.3.5 Capacity of the Integrated System -- 3.4 Related Works -- 3.5 Conclusions -- References -- 4 Precise-Spike-Driven Synaptic Plasticity for Hetero Association of Spatiotemporal Spike Patterns. , 4.1 Introduction -- 4.2 Methods -- 4.2.1 Spiking Neuron Model -- 4.2.2 PSD Learning Rule -- 4.3 Results -- 4.3.1 Association of Single-Spike and Multi-spike Patterns -- 4.3.2 Generality to Different Neuron Models -- 4.3.3 Robustness to Noise -- 4.3.4 Learning Capacity -- 4.3.5 Effects of Learning Parameters -- 4.3.6 Classification of Spatiotemporal Patterns -- 4.4 Discussion and Conclusion -- References -- 5 A Spiking Neural Network System for Robust Sequence Recognition -- 5.1 Introduction -- 5.2 The Integrated Network for Sequence Recognition -- 5.2.1 Rationale of the Whole System -- 5.2.2 Neural Encoding Method -- 5.2.3 Item Recognition with the PSD Rule -- 5.2.4 The Spike Sequence Decoding Method -- 5.3 Experimental Results -- 5.3.1 Learning Performance Analysis of the PSD Rule -- 5.3.2 Item Recognition -- 5.3.3 Spike Sequence Decoding -- 5.3.4 Sequence Recognition System -- 5.4 Discussions -- 5.4.1 Temporal Learning Rules and Spiking Neurons -- 5.4.2 Spike Sequence Decoding Network -- 5.4.3 Potential Applications in Authentication -- 5.5 Conclusion -- References -- 6 Temporal Learning in Multilayer Spiking Neural Networks Through Construction of Causal Connections -- 6.1 Introduction -- 6.2 Multilayer Learning Rules -- 6.2.1 Spiking Neuron Model -- 6.2.2 Multilayer PSD Rule -- 6.2.3 Multilayer Tempotron Rule -- 6.3 Heuristic Discussion on the Multilayer Learning Rules -- 6.4 Simulation Results -- 6.4.1 Construction of Causal Connections -- 6.4.2 The XOR Benchmark -- 6.4.3 The Iris Benchmark -- 6.5 Discussion and Conclusion -- References -- 7 A Hierarchically Organized Memory Model with Temporal Population Coding -- 7.1 Introduction -- 7.2 The Hierarchical Organized Memory Model -- 7.2.1 Neuron Models and Neural Oscillations -- 7.2.2 Temporal Population Coding -- 7.2.3 The Tempotron Learning and STDP -- 7.3 Simulation Results. , 7.3.1 Auto-Associative Memory -- 7.3.2 Episodic Memory -- 7.4 Discussion -- 7.4.1 Information Flow and Emergence of Neural Cliques -- 7.4.2 Storage, Recall and Organization of Memory -- 7.4.3 Temporal Compression and Information Binding -- 7.4.4 Related Works -- 7.5 Conclusion -- References -- 8 Spiking Neuron Based Cognitive Memory Model -- 8.1 Introduction -- 8.2 SRM-Based CA3 Model -- 8.2.1 Spike Response Model -- 8.2.2 SRM-Based Pyramidal Cell -- 8.2.3 SRM-Based Interneuron -- 8.3 Convergence of Synaptic Weight -- 8.4 Maximum Synaptic Weight to Prevent Early Activation -- 8.5 Pattern Completion of Auto-Associative Memory -- 8.6 Discussion -- 8.7 Conclusion -- References.
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  • 2
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Solid state phenomena Vol. 124-126 (June 2007), p. 899-902 
    ISSN: 1662-9779
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Physics
    Notes: Monodisperse FePt nanoparticles were synthesized by thermal decomposition of Fe(CO)5and reduction of Pt(acac)2 at low temperature of 160–180 °C by using kerosene as a solvent. Theaverage sizes of the synthesized particles ranged from 2.2 to 4.4 nm. Thermal annealing of theas-prepared FePt particles at 700 °C for 1 h transformed the crystalline structure of the particles froma disordered face-centered cubic to an ordered face-centered tetragonal. This change led to asignificant increase in coercivity from 153.37 to 2273.22 Oe and in saturated magnetization from26.86 to 41.21 emu/g
    Type of Medium: Electronic Resource
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  • 3
    Publication Date: 2016-06-10
    Description: Atmospheric wet nitrogen (N) and phosphorus (P) depositions are important sources of bioavailable N and P, and the input of N and P and their ratios significantly influence nutrient availability and balance in terrestrial as well as aquatic ecosystems. Here we monitored atmospheric P depositions by measuring monthly dissolved P concentration in rainfall at 41 field stations in China. Average deposition fluxes of N and P were 13.69 ± 8.69 kg N ha –1 a –1 (our previous study) and 0.21 ± 0.17 kg P ha –1 a –1 , respectively. Central and southern China had higher N and P deposition rates than northwest China, northeast China, Inner Mongolia, or Qinghai-Tibet. Atmospheric N and P depositions showed strong seasonal patterns and were dependent upon seasonal precipitation. Fertilizer and energy consumption were significantly correlated with N deposition but less correlated with P deposition. The N:P ratios of atmospheric wet deposition (with the average of 77 ± 40, by mass), were negatively correlated with current soil N:P ratios in different ecological regions, suggesting that the imbalanced atmospheric N and P deposition will alter nutrient availability and strengthen P limitation, which may further influence the structure and function of terrestrial ecosystems. The findings provide the assessments of both wet N and P deposition and their N:P ratio across China and indicate potential for strong impacts of atmospheric deposition on broad range of terrestrial ecosystems.
    Print ISSN: 0148-0227
    Topics: Biology , Geosciences
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  • 4
    Publication Date: 2016-05-20
    Description: Nature Immunology 17, 695 (2016). doi:10.1038/ni.3456 Authors: Shaojun Xing, Fengyin Li, Zhouhao Zeng, Yunjie Zhao, Shuyang Yu, Qiang Shan, Yalan Li, Farrah C Phillips, Peterson K Maina, Hank H Qi, Chengyu Liu, Jun Zhu, R Marshall Pope, Catherine A Musselman, Chen Zeng, Weiqun Peng & Hai-Hui Xue
    Print ISSN: 1529-2908
    Electronic ISSN: 1529-2916
    Topics: Biology , Medicine
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  • 5
    Publication Date: 2018-06-01
    Description: Author(s): Lei Liu, Bo Tian, Yu-Qiang Yuan, and Zhong Du In this paper, we investigate the coupled Sasa-Satsuma equations, which describe the simultaneous propagation of two ultrashort pulses in the birefringent or two-mode fiber with the third-order dispersion, self-steepening, and stimulated Raman scattering effects. Darboux-dressing transformation is a... [Phys. Rev. E 97, 052217] Published Thu May 31, 2018
    Keywords: Nonlinear Dynamics and Chaos
    Print ISSN: 1539-3755
    Electronic ISSN: 1550-2376
    Topics: Physics
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  • 6
    Publication Date: 2015-01-30
    Description: Cell loss due to apoptosis induced by oxidative stress is a major hurdle for endothelial progenitor cells (EPCs)-based therapy. Sirtuin 1 (SIRT1) plays important roles in many pathophysiological processes by deacetylating various substrates, including forkhead transcription factor (FOXO). However, after deacetylation, the fate of FOXO protein remains to be explored. In the present study, we investigated whether SIRT1 exerted a protective effect on hydrogen peroxide (H 2 O 2 )-induced EPCs apoptosis and, if so, what the underlying mechanism might be. EPCs were isolated and obtained from human umbilical cord blood by density gradient centrifugation and identified by morphology, tube formation ability, cell surface markers and the ability to take up acetylated low density lipoprotein (Dil-Ac-LDL) and bind ulex europaeus agglutinin 1 (FITC-UEA-1). Immunofluorescence showed that SIRT1 localized in the nucleus of EPCs in the presence or absence of H 2 O 2 . SIRT1 protein level in EPCs was increased by the treatment with H 2 O 2 for 24 h. Incubation of EPCs with H 2 O 2 dose dependently induced EPCs apoptosis. SIRT1 overexpression reduced the rate of EPCs apoptosis induced by H 2 O 2 , while SIRT1 downregulation and EX527, a specific SIRT1 inhibitor, exerted the opposite effect. SIRT1 overexpression decreased the total FOXO3a protein expression, whereas SIRT1 downregulation and EX527 increased the amount of FOXO3a protein. SIRT1 reduced FOXO3a transcriptional activity according to Bim expression. Co-immunoprecipitation (Co-IP) assay showed that SIRT1 could bind to FOXO3a, reduce its acetylation level and increase its ubiquitination level. To sum up, our work demonstrated that SIRT1 had a pivotally protective role in the regulation of EPCs apoptosis induced by H 2 O 2 and that SIRT1 protected against apoptosis by inhibiting FOXO3a via FOXO3a ubiquitination and subsequent degradation. This article is protected by copyright. All rights reserved
    Electronic ISSN: 1097-4652
    Topics: Biology , Medicine
    Published by Wiley-Blackwell
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  • 7
    Publication Date: 2016-04-02
    Description: Analytical Chemistry DOI: 10.1021/acs.analchem.5b04487
    Print ISSN: 0003-2700
    Electronic ISSN: 1520-6882
    Topics: Chemistry and Pharmacology
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  • 8
    Publication Date: 2018-03-28
    Description: Journal of the American Chemical Society DOI: 10.1021/jacs.8b00571
    Print ISSN: 0002-7863
    Electronic ISSN: 1520-5126
    Topics: Chemistry and Pharmacology
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  • 9
    Publication Date: 2015-03-12
    Description: Drosophila Down syndrome cell adhesion molecule 1 (Dscam1) plays a critical role in neural development. It can potentially form 38 016 isoforms through alternative RNA splicing, and exhibits isoform-specific homophilic interaction through three variable Ig domains (Ig2, Ig3 and Ig7). The diversity and homophilic interaction are essential for its functions. Ig7 has 33 isoforms and is the most variable among the three variable Ig domains. However, only one isoform of Ig7 (isoform 30) has been structurally determined to date. Here, two isoforms of Dscam1 Ig7 (isoforms 5 and 9; Ig7 5 and Ig7 9 ) were produced and crystallized. Diffraction data from Ig7 5 and Ig7 9 crystals were processed to resolutions of 1.95 and 2.37 Å, respectively. Comparison of different Dscam1 Ig7 isoforms will provide insight into the mechanism of its binding specificity.
    Electronic ISSN: 1744-3091
    Topics: Biology , Chemistry and Pharmacology , Geosciences , Physics
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  • 10
    Publication Date: 2015-02-12
    Description: Unbalanced voltage will inevitably cause power and DC voltage fluctuations in a three-phase PV system. The deterioration of power quality will do great harm to the PV panels and the loads, so it is necessary to suppress the power fluctuations. This paper further explores the coefficients control strategy of PV converters under unbalanced voltage conditions, aiming to suppress power fluctuations by controlling the injection of some specific orders of current harmonics into the grid. In order to achieve this, the current reference of the PV inverter has been changed by bringing in two control coefficients, and the expression of each order of the current harmonics has been deduced. Based on the standards of PV systems, the regions from which the coefficients can be selected are determined. Then, by tuning these coefficients in the feasible regions, the output parameters (power fluctuation, current THD and odd harmonics) can be controlled precisely. The model of this method is built and simulated in PSCAD/EMTDC, and as a result, it is shown that the power fluctuations can be restricted according to different power quality requirements.
    Electronic ISSN: 1996-1073
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Published by MDPI Publishing
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