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  • 2015-2019  (21)
  • 2010-2014  (22)
  • 1990-1994  (2)
  • 1960-1964  (1)
  • 1900-1904  (2)
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  • 1
    Keywords: Konferenzschrift
    Type of Medium: Online Resource
    Pages: 724 p , Ill., graph. Darst., Kt , 31 cm
    Edition: Online-Ausg. Online-Ressource
    ISBN: 9781786201461
    Series Statement: Engineering geology special publication 7
    DDC: 551.7/9
    Language: English
    Note: Includes bibliographical references and indexes , Systemvoraussetzungen:
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  • 2
    ISSN: 1546-1718
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] The search for tumour–specific markers is one of the chief goals in cancer biology. We show that the translocation t(12;16)(q13:p11) in malignant myxoid liposarcoma can be a fusion of the CHOP dominant negative transcription factor gene with a novel gene, FUS, which can result in fusion of ...
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    International journal of earth sciences 52 (1962), S. 280-292 
    ISSN: 1437-3262
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Description / Table of Contents: Abstract In the “Irumide”-Mountains of Northern Rhodesia, petrofabric analysis shows two intersecting systems of deformations being of different age. Each orogeny can be traced to a specific cycle of metamorphism. The earlier metamorphism was connected with a blastesis of plagioclase and with probable influx of sodium and calcium, the later-one with a strong addition of potassium. Final products of the first cycle occur (as small relict complexes of plagioclase-gneisses) within the whole area of highly metamorphous gneisses of the second phase. Gneisses containing porphyroblasts of potassium feldspars and granitic gneisses strike ENE and NE. At both flanks of the ENE-striking anticlinoria, blastesis of large euhedral microcline crystals and enrichment of potassium feldspars occur. Plagioclases and potassium feldspars of the older generations are found (as big inclusions) within the porphyroblasts of microcline belonging to the younger generation.
    Abstract: Résumé Dans le massif des Irumides (E.Ackermann 1950) en Rhodésie du Nord on trouve deux systèmes de déformation d'âge différent avec des directions distinctes et un cycle spécifique de métamorphoses. Pour la première métamorphose on constate une blastèse à plagioclase avec probablement un apport de Na et éventuellement de Ca—pour la dernière un fort apport de K. Les produits finaux du premier cycle, sous la forme de complexes résiduels à base de gneiss plagioclasiques, se rencontrent dans toute le région des gneiss fortement métamorphiques de la seconde phase. Des gneiss à porphyroblastes de feldspath de potasse et des granites gneissiques ont une direction ENE et NE. Une blastèse de grands microclines idiomorphes et de grands enrichissements en feldspath de potasse se sont effectués sur les flancs des zones de crête irumidiques de direction ENE. Les plagioclases avec leurs bordures à biotite de la génération plus ancienne sont entourés par des porphyroblastes à microcline dans les gneiss de Mkushi.
    Notes: Zusammenfassung Im Irumiden-Gebirge (E.Ackermann 1950) Nordrhodesiens konnten mit Hilfe von Gefüge-Auswertungen zwei altersverschiedene tektonische Verformungspläne mit jeweils voneinander abweichenden Richtungen herausgestellt werden. Jedem der orogenetischen Abläufe kann ein spezifischer Metamorphose-Zyklus zugeordnet werden. Für die erste Metamorphose ist eine Plagioklas-Blastese mit vermutlicher Natrium- und eventuell auch Kalziumzufuhr, für die letzte eine sehr kräftige Kalizufuhr von größter Bedeutung. Die Plagioklas-reichen Gneise, die Endprodukte der ersten Metamorphose, sind in kleineren reliktischen Komplexen über das gesamte Gebiet verbreitet, während sich die Kalifeldspat-Porphyroblasten-Gneise und Gneis-Granite auf ENE und NE gerichtete und in dieser Richtung vielfach gelängte und durchbewegte Züge verteilen. Zur Sprossung von sehr großen idiomorphen Mikroklinen und zu großen KF-Anreicherungen kommt es zu beiden Seiten der irumidisch-ENE-gerichteten Scheitelzonen (siehe E.Ackermann und A.Forster 1960). Innerhalb dieser hochmetamorphen Gneise und Gneisgranite treten die erstgenannten Plagioklas-betonten Gneise als reliktische, unverdaute Schollen auf. Die Plagioklase und wenigen Kalifeldspäte der älteren Feldspatgeneration werden zusammen mit ihren Biotitsäumen in den bis zu Kinderkopf-großen jüngeren Mikroklinporphyroblasten der sogenannten Mkushi-Gneise eingeschlossen.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Fresenius' Zeitschrift für analytische Chemie 42 (1903), S. 64-68 
    ISSN: 1618-2650
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1618-2650
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 6
    Publication Date: 2018-03-05
    Description: Despite multidisciplinary local and systemic therapeutic approaches, the prognosis for most patients with brain metastases is still dismal. The role of adaptive and innate anti-tumor response including the Hum...
    Electronic ISSN: 2051-5960
    Topics: Medicine
    Published by BioMed Central
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  • 7
    Publication Date: 2018-06-23
    Description: Introduction Exercise prehabilitation may improve outcomes after surgery. Frailty is a key predictor of adverse postoperative outcomes in older people; the multidimensional nature of frailty makes this a population who may derive substantial benefit from exercise prehabilitation. The objective of this trial is to test the efficacy of exercise prehabilitation to improve postoperative functional outcomes for people living with frailty having cancer surgery with curative intent. Methods and analysis We will conduct a single-centre, parallel-arm randomised controlled trial of home-based exercise prehabilitation versus standard care among consenting patients 〉60 years having elective cancer surgery (intra-abdominal and intrathoracic) and who are frail (Clinical Frailty Scale 〉4 ) . The intervention consists of 〉 3 weeks of exercise prehabilitation (strength, aerobic and stretching). The primary outcome is the 6 min walk test at the first postoperative clinic visit. Secondary outcomes include the short physical performance battery, health-related quality of life, disability-free survival, complications and health resource utilisation. The primary outcome will be analysed by intention to treat using analysis of covariance. Outcomes up to 1 year after surgery will be ascertained through linkage to administrative data. Ethics and dissemination Ethical approval has been granted by our ethics review board (Protocol Approval #2016009–01H). Results will be disseminated through presentation at scientific conferences, through peer-reviewed publication, stakeholder organisations and engagement of social and traditional media. Trial registration number NCT02934230 ; Pre-results.
    Keywords: Surgery, Open access, Surgery
    Electronic ISSN: 2044-6055
    Topics: Medicine
    Published by BMJ Publishing
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  • 8
    Publication Date: 2013-12-19
    Description: Data on rock thermal conductivity (TC) are important for the quantification of the subsurface temperature regime and for the determination of heat flow. If drill core is not retrieved from boreholes and thus no laboratory measurement of TC can be made, other methods are desired to determine TC. One of these methods is the prediction of TC from well logs. We have examined the relationships between TC and standard well-log data (gamma ray, density, sonic interval transit time, hydrogen index and photoelectric factor) by a theoretical analysis and by using real subsurface data from four boreholes of the North German Basin. The theoretical approach comprised the calculation of TC from well-log response values for artificial sets of mineral assemblages consisting of variable contents of 15 rock-forming minerals typical for sedimentary rocks. The analysis shows different correlation trends between TC and the theoretical well-log response in dependence on the mineral content, affecting the rock matrix TC, and on porosity. The analysis suggests the development of empirical equations for the prediction of matrix TC separately for different groups of sedimentary rocks. The most valuable input parameters are the volume fraction of shale, the matrix hydrogen index and the matrix density. The error of matrix TC prediction is on the order of 4.2 ± 3.2 per cent (carbonates), 7.0 ± 5.6 per cent (evaporites), and 11.4 ± 9.1 per cent (clastic rocks). From the subsurface data, comprising measured TC values ( n  = 1755) and well-log data, four prediction equations for bulk TC were developed resembling different lithological compositions. The most valuable input parameters for these predictions are the volume fraction of shale, the hydrogen index and the sonic interval transit time. The equations predict TC with an average error between 5.5 ± 4.1 per cent (clean sandstones of low porosity; Middle Buntsandstein), 8.9 ± 5.4 per cent (interbedding of sandstone, silt- and claystones; Wealden), and 9.4 ± 11 per cent (shaly sandstones; Stuttgart Fm.). An equation including all clastic rock data yields an average error of 11 ± 10 per cent. The subsurface data set also was used to validate the prediction equation for matrix TC established for clastic rocks. Comparison of bulk TC, computed from the matrix TC values and well-log porosity according to the geometric-mean model, to measured bulk TC results in an accuracy 〈15 per cent. A validation of the TC prediction at borehole scale by comparison of measured temperature logs and modeled temperature logs (based on the site-specific surface heat flow and the predicted TC) shows an excellent agreement in temperature. Interval temperature gradients vary on average by 〈3 K km –1 and predicted compared to measured absolute temperature fitted with an accuracy 〈5 per cent. Compared to previously published TC prediction approaches, the developed matrix and bulk TC prediction equations show significantly higher prediction accuracy. Bulk TC ranging from 1.5 to 5.5 W (m K) –1 is always predicted with an average error 〈10 per cent relative to average errors between 15 and 35 per cent resulting from the application to our data set of the most suitable methods from literature.
    Print ISSN: 0956-540X
    Electronic ISSN: 1365-246X
    Topics: Geosciences
    Published by Oxford University Press on behalf of The Deutsche Geophysikalische Gesellschaft (DGG) and the Royal Astronomical Society (RAS).
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  • 9
    Publication Date: 2015-07-10
    Description: Introduction The transfer of patient care between the intensive care unit (ICU) and the hospital ward is associated with increased risk of medical error and adverse events. This study will describe patient transfer from ICU to hospital ward by documenting (1) patient, family and provider experiences related to ICU transfer, (2) communication between stakeholders involved in ICU transfer, (3) adverse events that follow ICU transfer and (4) opportunities to improve ICU to hospital ward transfer. Methods This is a mixed methods prospective observational study of ICU to hospital ward transfer practices in 10 ICUs across Canada. We will recruit 50 patients at each site (n=500) who are transferred from ICU to hospital ward, and distribute surveys to enrolled patients, family members, and healthcare providers (ICU and ward physicians and nurses) after patient transfer. A random sample of 6 consenting study participants (patients, family members, healthcare providers) from each study site (n=60) will be offered an opportunity to participate in interviews to further describe stakeholders’ experience with ICU to hospital ward transfer. We will abstract information from patient health records to identify clinical data and use of transfer tools, and identify adverse events that are related to the transfer. Ethics and Dissemination Research ethics board approval has been obtained at the coordinating study centre (UofC REB13-0021) and 5 study sites (UofA Pro00050646; UBC-PHC H14-01667; Sunnybrook 336-2014; QCH 14-07; Sherbrooke 14-172). Dissemination of the findings will provide a comprehensive description of transfer from ICU to hospital ward in Canada including the uptake of validated or local transfer tools, a conceptual framework of the experiences and needs of stakeholders in the ICU transfer process, a summary of adverse events experienced by patients after transfer from ICU to hospital ward, and opportunities to guide quality improvement efforts.
    Keywords: Open access, Communication, Evidence based practice, Health services research, Intensive care, Patient-centred medicine
    Electronic ISSN: 2044-6055
    Topics: Medicine
    Published by BMJ Publishing
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  • 10
    Publication Date: 2015-08-27
    Description: Introduction Increased frequency and intensity of inpatient therapy contributes to improved outcomes for stroke survivors. Differences exist in the amount of therapy provided internationally. In England, Wales and Northern Ireland it is recommended that a minimum of 45 min of each active therapy should be provided at least 5 days a week provided the therapy is appropriate and that the patient can tolerate this. Sentinel Stroke National Audit Programme (2014) data demonstrate this standard is not being achieved for most patients. No research been undertaken to explore how therapists in England manage their practice to meet time-specific therapy recommendations. The ReAcT study aims to develop an in-depth understanding of stroke therapy provision, including how the guideline of 45 min a day of each relevant therapy, is interpreted and implemented by therapists, and how it is experienced by stroke-survivors and their families. Methods and analysis A multisite ethnographic case study design in a minimum of six stroke units will include modified process mapping, observations of service organisation, therapy delivery and documentary analysis. Semistructured interviews with therapists and service managers (n=90), and with patients and informal carers (n=60 pairs) will be conducted. Data will be analysed using the Framework approach. Ethics and dissemination The study received a favourable ethical opinion via the National Research Ethics Service (reference number: 14/NW/0266). Participants will provide written informed consent or, where stroke-survivors lack capacity, a consultee declaration will be sought. ReAcT is designed to generate insights into the organisational, professional, social, practical and patient-related factors acting as facilitators or barriers to providing the recommended amount of therapy. Provisional recommendations will be debated in consensus meetings with stakeholders who have not participated in ReAcT case studies or interviews. Final recommendations will be disseminated to therapists, service managers, clinical guideline developers and policymakers and stroke-survivors and informal carers.
    Keywords: Open access, Health services research, Neurology, Qualitative research
    Electronic ISSN: 2044-6055
    Topics: Medicine
    Published by BMJ Publishing
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