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  • 1
    In: Journal of Nanomaterials, Hindawi Limited, Vol. 2021 ( 2021-8-26), p. 1-9
    Abstract: The production of zinc oxide nanoparticles (ZnO NPs) utilizing different vegetable extracts (onion, cabbage, carrot, and tomato) was performed in this research owing to its excellency over other methods of synthesis, namely, simplicity, environmental friendliness, and the elimination of harmful compounds. Fresh extracted onion, cabbage, carrot, and tomato of ZnO NPs are characterized by Fourier transform infrared (FTIR), X-ray diffraction (XRD), scanning electron microscopy (SEM), and UV-visible spectroscopy. FTIR findings demonstrate that the prepared nanoparticles were observed in the spectrum of 626 cm-1–1219 cm-1 with some other functional groups. Wurtzite hexagonal structure of the prepared ZnO NPs was observed from XRD results. In addition, the prepared nanoparticles were failed into nanoscales (17 nm, 18 nm, 24 nm, and 15 nm) calculated from Scherrer’s equation. Nearly spherical shapes were seen from SEM image for onion and tomato extraction while rod and tube for carrot and cabbage, respectively. Two broad peaks were observed from UV-vis spectroscopy results for each extract. The presence of a wide range of energy bandgaps in the region of 3-4 eV was detected, indicating that ZnO NP material can be employed in metal oxide semiconductor-based systems. The dye-sensitive solar cell based on ZnO NPs has been successfully synthesized, and the efficiency of the device has been evaluated by measuring the current density-voltage behaviour under the presence of artificial sunshine. The increased effectiveness of the manufactured dye-sensitive solar cell is attributable to a large improvement in dye molecular adsorption onto the surface of ZnO NPs. Thus, the usage of the green produced ZnO NPs with creating dye sensitivity solar cell is a simple and viable way for the well-being of our future.
    Type of Medium: Online Resource
    ISSN: 1687-4129 , 1687-4110
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2021
    detail.hit.zdb_id: 2229480-6
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  • 2
    Online Resource
    Online Resource
    Marwah Infotech ; 2022
    In:  Asian Pacific Journal of Health Sciences Vol. 9, No. 1 ( 2022-01-15), p. 106-109
    In: Asian Pacific Journal of Health Sciences, Marwah Infotech, Vol. 9, No. 1 ( 2022-01-15), p. 106-109
    Abstract: Introduction: Poly Cystic Ovarian Syndrome (PCOS) is one of the most common endocrine conditions, usually begins in adolescence and prominent in more than 75% of the adult population. Aim: The aim of the study was to assess the nutritional status of emerging adult women with PCOS. Objectives: The objectives of the study were to assess the nutritional status of the selected emerging adult women with PCOS using anthropometric, biochemical, and clinical parameters. Methodology: Prospective interventional design was adopted in the study to test the hypothesis framed and stated above. Emerging adult women between 18 and 23 years of age and who were free from other diseases were included for the study from SRHER (DU) and a working women hostel (Vaanavil Hostel) in Porur, Chennai. Anthropometric, biochemical, and clinical assessment were performed for 57 selected emerging adult women “at risk” for PCOS. Results: The mean height, weight, BMI, waist and hip circumference, and WHR of 57 “at risk” emerging adult women was found to be, 160.4± 6.7 cms, 60.7 ± 7.5 kg, 23.6 ± 2.9, 95.9 ± 10.6 cm, 119.1 ± 13.0 cm, and 0.80 ± 0.05, respectively. The mean biochemical parameters, namely, FBS, fasting insulin, total testosterone, total cholesterol, HDL, LDL, and TGL were 98.4 ± 19.7 (mgs/dl), 13.04 ± 6.4 (mcU/ml), 30.9 ± 13.6 (ng/dl), 170.2 ± 36.3 (mgs/dl), 47.7 ± 7.9 (mgs/dl), 115 ± 26.9 (mgs/dl), and 173.5 ± 43.2 (mgs/dl), respectively. It was observed that 25 (44%) had acne, 16 (33%) had hirsutism, 2 (4%) had dark discoloration of the skin, and 5 (9%) had both acne and hirsutism. Conclusion: The mean height was within the standard range; however, the body weight, BMI, waist and hip circumference, and WHR were higher. The mean biochemical parameters analyzed were within the normal range. Acne, hirsutism, and dark patches were observed.
    Type of Medium: Online Resource
    ISSN: 2349-0659 , 2350-0964
    Language: Unknown
    Publisher: Marwah Infotech
    Publication Date: 2022
    detail.hit.zdb_id: 3030889-6
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  • 3
    In: BMC Genomics, Springer Science and Business Media LLC, Vol. 23, No. 1 ( 2022-12)
    Abstract: Aspergillus flavus , one of the causative agents of human fungal keratitis, can be phagocytosed by human corneal epithelial (HCE) cells and the conidia containing phagosomes mature into phagolysosomes. But the immunological responses of human corneal epithelial cells interacting with A. flavus are not clear. In this study, we report the expression of immune response related genes of HCE cells exposed to A. flavus spores using targeted transcriptomics. Methods Human corneal epithelial cell line and primary cultures were grown in a six-well plate and used for coculture experiments. Internalization of the conidia was confirmed by immunofluorescence microscopy of the colocalized endosomal markers CD71 and LAMP1. Total RNA was isolated, and the quantity and quality of the isolated RNA were assessed using Qubit and Bioanalyzer. NanoString nCounter platform was used for the analysis of mRNA abundance using the Human Immunology panel. R-package and nSolver software were used for data analysis. KEGG and FunRich 3.1.3 tools were used to analyze the differentially expressed genes. Results Different morphotypes of conidia were observed after 6 h of coculture with human corneal epithelial cells and found to be internalized by epithelial cells. NanoString profiling showed more than 20 differentially expressed genes in immortalized human corneal epithelial cell line and more than ten differentially expressed genes in primary corneal epithelial cells. Distinct set of genes were altered in their expression in cell line and primary corneal epithelial cells. KEGG pathway analysis revealed that genes associated with TNF signaling, NF-KB signaling, and Th17 signaling were up-regulated, and genes associated with chemokine signaling and B cell receptor signaling were down regulated. FunRich pathway analysis showed that pathways such as CDC42 signaling, PI3K signaling, and Arf6 trafficking events were activated by the clinical isolates CI1123 and CI1698 in both type of cells. Conclusions Combining the transcript analysis data from cell lines and primary cultures, we showed the up regulation of immune defense genes in A. flavus infected cells. At the same time, chemokine signaling and B cell signaling pathways are downregulated. The variability in the expression levels in the immortalized cell line and the primary cultures is likely due to the variable epigenetic reprogramming in the immortalized cells and primary cultures in the absence of any changes in the genome. It highlights the importance of using both cell types in host-pathogen interaction studies.
    Type of Medium: Online Resource
    ISSN: 1471-2164
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2022
    detail.hit.zdb_id: 2041499-7
    SSG: 12
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  • 4
    Online Resource
    Online Resource
    Institute of Medico-legal Publications Private Limited ; 2020
    In:  Indian Journal of Public Health Research & Development Vol. 11, No. 2 ( 2020-02-01), p. 192-
    In: Indian Journal of Public Health Research & Development, Institute of Medico-legal Publications Private Limited, Vol. 11, No. 2 ( 2020-02-01), p. 192-
    Type of Medium: Online Resource
    ISSN: 0976-5506 , 0976-0245
    Language: Unknown
    Publisher: Institute of Medico-legal Publications Private Limited
    Publication Date: 2020
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  • 5
    In: Drug Development and Industrial Pharmacy, Informa UK Limited, Vol. 47, No. 4 ( 2021-04-03), p. 562-568
    Type of Medium: Online Resource
    ISSN: 0363-9045 , 1520-5762
    Language: English
    Publisher: Informa UK Limited
    Publication Date: 2021
    detail.hit.zdb_id: 2008903-X
    SSG: 15,3
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