In:
Epigenomics, Future Medicine Ltd, Vol. 15, No. 5 ( 2023-03), p. 307-334
Kurzfassung:
ncRNAs, particularly miRNAs, lncRNAs and circRNAs, are a group of RNAs which, although they do not encode proteins (however, recent evidence shows that certain circRNAs are translatable), play a major role in regulating gene expression and, therefore, affect multiple cellular processes, in particular apoptosis. Apoptosis is proven to mediate myocardial infarction physiopathology in addition to ischemic necrosis and, therefore, has recently gained great interest as a target to improve MI outcomes. The current work reviews studies that have assessed ncRNAs with the ability to promote or suppress apoptosis in the process of MI and, therefore, may introduce new therapeutic targets for MI treatment.
Materialart:
Online-Ressource
ISSN:
1750-1911
,
1750-192X
DOI:
10.2217/epi-2022-0451
Sprache:
Englisch
Verlag:
Future Medicine Ltd
Publikationsdatum:
2023
SSG:
12
Permalink