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  • 1
    Online Resource
    Online Resource
    Outcomes of monochorionic twins with twin reversed arterial perfusion sequence: interstitial laser versus cord occlusion
    Elsevier BV ; 2024
    In:  European Journal of Obstetrics & Gynecology and Reproductive Biology Vol. 293 ( 2024-02), p. 15-16
    Details
    In: European Journal of Obstetrics & Gynecology and Reproductive Biology, Elsevier BV, Vol. 293 ( 2024-02), p. 15-16
    Type of Medium: Online Resource
    ISSN: 0301-2115
    URL: Article
    DOI: 10.1016/j.ejogrb.2023.08.058
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2024
    detail.hit.zdb_id: 2005196-7
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  • 2
    Online Resource
    Online Resource
    Percutaneous Intratumor Laser Ablation for Fetal Sacrococcygeal Teratoma
    S. Karger AG ; 2020
    In:  Fetal Diagnosis and Therapy Vol. 47, No. 2 ( 2020), p. 138-144
    Details
    In: Fetal Diagnosis and Therapy, S. Karger AG, Vol. 47, No. 2 ( 2020), p. 138-144
    Abstract: 〈 b 〉 〈 i 〉 Objective: 〈 /i 〉 〈 /b 〉 To evaluate the efficiency of percutaneous intratumor laser ablation for fetal solid sacrococcygeal teratoma (SCT). 〈 b 〉 〈 i 〉 Subjects and Methods: 〈 /i 〉 〈 /b 〉 We carried out percutaneous ultrasound-guided intratumor laser ablation through a 17-gauge needle using an output of 40 W in 7 fetuses with large solid SCT and reviewed the literature for minimally invasive therapy for this condition. 〈 b 〉 〈 i 〉 Results: 〈 /i 〉 〈 /b 〉 Laser ablation was carried out at a median gestational age of 20 (range 19–23) weeks, and in all cases there was elimination of obvious vascularization within the tumor and improvement in cardiac function. Three (43%) babies survived and had surgical excision of the tumor within 2 days of birth, 3 liveborn babies died within 5 days of birth and before surgery, and 1 fetus died within 2 weeks after the procedure. In previous series of various percutaneous interventions for predominantly solid SCT the survival rate was 33% (2/6) (95% CI 9.7–70%) for endoscopic laser to superficial vessels, 57% (4/7) (95% CI 25–84%) for intratumor laser, 67% (8/12) (95% CI 39–86%) for intratumor radiofrequency ablation, and 20% (1/5) (95% CI 3.6–62%) for intratumor injection of alcohol. 〈 b 〉 〈 i 〉 Conclusions: 〈 /i 〉 〈 /b 〉 In solid SCT, the reported survival from intratumor laser or radiofrequency ablation is about 50%, but survival does not mean success, and it remains uncertain whether such interventions are beneficial or not because the number of fetuses is small and there were no controls that were managed expectantly.
    Type of Medium: Online Resource
    ISSN: 1015-3837 , 1421-9964
    URL: Article
    DOI: 10.1159/000500775
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2020
    detail.hit.zdb_id: 1482292-1
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  • 3
    Online Resource
    Online Resource
    Management Options for Fetal Bronchopulmonary Sequestration
    MDPI AG ; 2022
    In:  Journal of Clinical Medicine Vol. 11, No. 6 ( 2022-03-20), p. 1724-
    Details
    In: Journal of Clinical Medicine, MDPI AG, Vol. 11, No. 6 ( 2022-03-20), p. 1724-
    Abstract: To evaluate the prenatal course and perinatal outcome of fetuses with bronchopulmonary sequestration (BPS) managed expectantly or using minimally invasive methods. This was a retrospective study of 29 fetuses with suspected BPS managed between 2010 and 2021 in three fetal medicine centers in Poland. Medline was searched to identify cases of BPS managed expectantly or through minimally-invasive methods. In 16 fetuses with BPS, there was no evidence of cardiac compromise. These fetuses were managed expectantly. Thirteen hydropic fetuses with BPS qualified for intrauterine intervention: a thoraco-amniotic shunt (TAS) was inserted in five fetuses, laser coagulation of the feeding vessel was performed in seven cases, and one fetus had combined treatment. In the combined data from the previous and the current study of various percutaneous interventions for BPS associated with hydrops, the survival rate was 91.2% (31/34) for TAS, 98.1% (53/54) for laser coagulation, and 75% (3/4) for intratumor injection of sclerosant. After taking into account cases with available data, the rate of preterm birth before 37 weeks in the group treated with laser coagulation was 14.3% (7/49) compared to 84.6% (22/26) in the group treated with TAS. The need for postnatal sequestrectomy was lower in the group of fetuses treated with laser coagulation 23.5% (12/51) in comparison to fetuses treated with TAS 84% (21/26). In fetuses with BPS without hydrops, progression of the lesion’s volume, leading to cardiac compromise, is unlikely. In hydropic fetuses with BPS, intrauterine therapy using minimally invasive methods prevents fetal demise. Both, the rate of preterm birth and the need for postnatal surgery is significantly lower in the group treated with laser coagulation compared to the group treated with TAS.
    Type of Medium: Online Resource
    ISSN: 2077-0383
    URL: Article
    DOI: 10.3390/jcm11061724
    Language: English
    Publisher: MDPI AG
    Publication Date: 2022
    detail.hit.zdb_id: 2662592-1
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  • 4
    Online Resource
    Online Resource
    Fetal therapy guidelines of the Polish Society of Gynecologists and Obstetricians — Fetal Therapy Section
    VM Media Group sp. z o.o ; 2024
    In:  Ginekologia Polska
    Details
    In: Ginekologia Polska, VM Media Group sp. z o.o
    Type of Medium: Online Resource
    ISSN: 2543-6767 , 0017-0011
    URL: Article
    DOI: 10.5603/gpl.100108
    Language: Unknown
    Publisher: VM Media Group sp. z o.o
    Publication Date: 2024
    detail.hit.zdb_id: 2601802-0
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  • 5
    Online Resource
    Online Resource
    Family (systemic) factors influencing life standards and health of working class
    Quarterly Journal Fides et Ratio ; 2023
    In:  Kwartalnik Naukowy Fides et Ratio Vol. 53, No. 1 ( 2023-03-28), p. 137-143
    Details
    In: Kwartalnik Naukowy Fides et Ratio, Quarterly Journal Fides et Ratio, Vol. 53, No. 1 ( 2023-03-28), p. 137-143
    Abstract: Adults function simultaneously in several areas, among which the most important ones are family and work. In these areas, they meet their needs and experience satisfaction as long as they are able to use them in a mature way. This, in turn, is largely conditioned by previous experiences–those from childhood. The article is a reflection on systemic factors affecting the quality of life and personality maturity of adults. Almost all of us are brought up in families. From the family we take behavior patterns, experience patterns and personality traits. Our traits, schema, and patterns of behavior affect our quality of life and maturity. Therefore, it is important that they are optimal and functional. The author uses the knowledge and research in the field of family psychology and family therapy. The definitions of a mature personality according to Irwin Yalom (therapist) and the concepts of a positive quality of life are adopted. Numerous Polish and foreign studies are cited to show the relationship between professional success and life satisfaction and the personality traits previously shaped in the family. The author presents the characteristics of families that are conducive to the maturity of their members. Special attention is drawn to the importance of the marital relationship and the sense of happiness of the spouses as the factors determining the functioning of the whole family and affecting it so that it becomes either healthy or dysfunctional. The author emphasises the characteristics of families related to their structure, communication, system boundaries and self-esteem. She writes about the dynamic balance of the family and the freedom to express one’s own thoughts and feelings as the key features of a proper family system. When children experience family characteristics which are conducive to a mature personality, health and a sense of happiness, then, as adults, they succeed in various fields of life. Therefore, it seems extremely important to reflect on systemic (family) factors affecting the quality of life and human maturity.
    Type of Medium: Online Resource
    ISSN: 2082-7067 , 2082-7067
    URL: Article
    DOI: 10.34766/fetr.v53i1.1129
    Language: Unknown
    Publisher: Quarterly Journal Fides et Ratio
    Publication Date: 2023
    detail.hit.zdb_id: 2700406-5
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  • 6
    Online Resource
    Online Resource
    GntR-like SCO3932 Protein Provides a Link between Actinomycete Integrative and Conjugative Elements and Secondary Metabolism
    MDPI AG ; 2021
    In:  International Journal of Molecular Sciences Vol. 22, No. 21 ( 2021-11-01), p. 11867-
    Details
    In: International Journal of Molecular Sciences, MDPI AG, Vol. 22, No. 21 ( 2021-11-01), p. 11867-
    Abstract: Streptomyces bacteria produce a plethora of secondary metabolites including the majority of medically important antibiotics. The onset of secondary metabolism is correlated with morphological differentiation and controlled by a complex regulatory network involving numerous regulatory proteins. Control over these pathways at the molecular level has a medical and industrial importance. Here we describe a GntR-like DNA binding transcription factor SCO3932, encoded within an actinomycete integrative and conjugative element, which is involved in the secondary metabolite biosynthesis regulation. Affinity chromatography, electrophoresis mobility shift assay, footprinting and chromatin immunoprecipitation experiments revealed, both in vitro and in vivo, SCO3932 binding capability to its own promoter region shared with the neighboring gene SCO3933, as well as promoters of polyketide metabolite genes, such as cpkD, a coelimycin biosynthetic gene, and actII-orf4—an activator of actinorhodin biosynthesis. Increased activity of SCO3932 target promoters, as a result of SCO3932 overproduction, indicates an activatory role of this protein in Streptomyces coelicolor A3(2) metabolite synthesis pathways.
    Type of Medium: Online Resource
    ISSN: 1422-0067
    URL: Article
    DOI: 10.3390/ijms222111867
    Language: English
    Publisher: MDPI AG
    Publication Date: 2021
    detail.hit.zdb_id: 2019364-6
    SSG: 12
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