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  • SAGE Publications  (3)
  • 2020-2024  (3)
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  • SAGE Publications  (3)
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  • 2020-2024  (3)
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  • 1
    Online Resource
    Online Resource
    SAGE Publications ; 2023
    In:  American Journal of Rhinology & Allergy Vol. 37, No. 5 ( 2023-09), p. 563-570
    In: American Journal of Rhinology & Allergy, SAGE Publications, Vol. 37, No. 5 ( 2023-09), p. 563-570
    Abstract: Eosinophilic chronic rhinosinusitis with nasal polyps (Eos-CRSwNP) remains a recalcitrant disease with a high recurrence rate. Objective This study aimed to identify a predictor of long-term recurrence in patients with Eos-CRSwNP. Methods A total of 39 Eos-CRSwNP patients who had their initial and recurrent nasal polyps surgically removed were retrospectively included in this study, with 49 Eos-CRSwNP patients without recurrence and 32 patients with non-Eos-CRSwNP matched by randomly chosen. Clinical characteristics were compared among or between groups. Spearman correlation analyses and a backward stepwise multivariate logistic regression analysis were performed to find factors associated with the recurrence and recurrence time of Eos-CRSwNP. Furthermore, a receiver operating characteristic (ROC) curve was used to determine the predictor of long-term Eos-CRSwNP recurrence. Results The number and ratio of tissue eosinophils were highest in Eos-CRSwNP with recurrence and lowest in non-Eos-CRSwNP. The ratio of tissue lymphocytes was highest in non-Eos-CRSwNP and lowest in Eos-CRSwNP with recurrence, with the number of tissue lymphocytes higher in Eos-CRSwNP without recurrence than the other two groups. The numbers of tissue lymphocytes in the initial nasal polyps were lower and the numbers of tissue eosinophils were higher in the group of recurrent nasal polyps that recurred at 〉 5 years after surgery than in the nasal polyps that recurred at 〈 5 years after surgery. The tissue lymphocyte-to-eosinophil ratio (LER) showed a significant negative correlation with the recurrence and the recurrence time of Eos-CRSwNP. A ROC curve revealed that a tissue LER value  〈  0.67 predicted long-term Eos-CRSwNP recurrence with 72.73% sensitivity and 82.35% specificity (area under the curve  =  0.789). Conclusion Tissue LER is strongly associated with Eos-CRSwNP recurrence and may play a key role in predicting long-term Eos-CRSwNP recurrence.
    Type of Medium: Online Resource
    ISSN: 1945-8924 , 1945-8932
    RVK:
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2554548-6
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  • 2
    Online Resource
    Online Resource
    SAGE Publications ; 2021
    In:  Journal of Vibration and Control Vol. 27, No. 17-18 ( 2021-09), p. 1979-1990
    In: Journal of Vibration and Control, SAGE Publications, Vol. 27, No. 17-18 ( 2021-09), p. 1979-1990
    Abstract: Earthquake is one of the major factors that provoke train derailment. To investigate dynamic responses of the train–slab ballastless track–subgrade system and derailment features of the train subjected to earthquake, a first large-scale shaking table test on this system was carried out in China. The loaded seismic wave is an earthquake wave of Zhengzhou Yellow River Bridge Site provided by the China Earthquake Administration. It was observed that the elevation of subgrade and embankment could magnify acceleration responses, and the transverse amplification effect of the elevation in soil was more pronounced than the vertical amplification effect. The acceleration response of a track slab was weaker than that of the top subgrade because of integrality and rigidity of the track slab. The bogie shows a shock-absorbing effect in the transverse direction. When the input amplitude was not larger than 0.14 g, the transverse and the vertical acceleration of the rail increased with rising earthquake amplitudes and fluctuated later. Meanwhile, the current stopping threshold for trains is conservative because the derailment factor was less than 0.8 and the peak lateral displacement of wheels was much smaller than the cross-sectional size of the rail model under a 0.12 g earthquake excitation. The current stopping threshold in codes could be reasonable in view of limited quantity and limited types of loaded earthquake in the test. The critical derailment condition of trains was 0.23 g when the Zhengzhou Yellow River Bridge Site earthquake was loaded, and the displacement analysis showed that it would be a great danger for train safety.
    Type of Medium: Online Resource
    ISSN: 1077-5463 , 1741-2986
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2021
    detail.hit.zdb_id: 2070247-4
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  • 3
    Online Resource
    Online Resource
    SAGE Publications ; 2021
    In:  Journal of International Medical Research Vol. 49, No. 5 ( 2021-05), p. 030006052110083-
    In: Journal of International Medical Research, SAGE Publications, Vol. 49, No. 5 ( 2021-05), p. 030006052110083-
    Abstract: To investigate the different risk factors among different subtypes of patients with acute coronary syndrome (ACS). Methods A total of 296 patients who had ACS were retrospectively enrolled. Blood and echocardiographic indices were assessed within 24 hours after admission. Differences in risk factors and Gensini scores of coronary lesions among three groups were analyzed. Results Univariate analysis of risk factors for ACS subtypes showed that age, and levels of fasting plasma glucose, amino-terminal pro-brain natriuretic peptide, and creatine kinase isoenzyme were significantly higher in patients with non-ST-segment elevation myocardial infarction (NSTEMI) than in those with unstable angina pectoris (UAP). Logistic multivariate regression analysis showed that amino-terminal pro-brain natriuretic peptide and the left ventricular ejection fraction (LVEF) were related to ACS subtypes. The left ventricular end-diastolic diameter was an independent risk factor for UAP and ST-segment elevation myocardial infarction (STEMI) subtypes. The severity of coronary stenosis was significantly higher in NSTEMI and STEMI than in UAP. Gensini scores in the STEMI group were positively correlated with D-dimer levels (r = 0.429) and negatively correlated with the LVEF (r = −0.602). Conclusion Different subtypes of ACS have different risk factors. Our findings may have important guiding significance for ACS subtype risk assessment and clinical treatment.
    Type of Medium: Online Resource
    ISSN: 0300-0605 , 1473-2300
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2021
    detail.hit.zdb_id: 2082422-1
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