GLORIA

GEOMAR Library Ocean Research Information Access

X

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • MDPI AG  (11)
  • 2020-2024  (11)
  • 1
    Online Resource
    Online Resource
    Prevalence and Factors Associated with Psychological Problems of Healthcare Workforce in Vietnam: Findings from COVID-19 Hotspots in the National Second Wave
    MDPI AG ; 2021
    In:  Healthcare Vol. 9, No. 6 ( 2021-06-11), p. 718-
    Details
    In: Healthcare, MDPI AG, Vol. 9, No. 6 ( 2021-06-11), p. 718-
    Abstract: Adopting a cross-sectional study design, we aimed to examine the prevalence of psychological problems in different healthcare workers during the COVID-19 pandemic in the hospitals in these COVID-19 hotspots (Da Nang city and Quang Nam province) and to explore the socioeconomic and COVID-19 control-related factors that are associated with various psychological problems. A total of 611 healthcare workers were included in the final analysis from 1 August 2020 to 31 August 2020. The prevalence of anxiety, depression, insomnia, and overall psychological problems was 26.84%, 34.70%, 34.53%, and 46.48%, respectively. The prevalence rates of anxiety were approximately equal amongst the groups of healthcare workers, and moderate-to-severe anxiety was the most common in physicians (11.11%). The prevalence of depression was the highest in nurses (38.65%) and moderate-to-severe depression was mainly found in physicians (11.81%). The prevalence rates of insomnia were 34.03% in physicians, 36.20% in nurses, and 31.21% in technicians; in particular, the rate of moderate-to-severe insomnia was higher in physicians and nurses compared to technicians. The prevalence of overall moderate-to-severe psychological problems was the highest among physicians (14.58%), followed by nurses (12.58%) and technicians (9.22%). Statistically significant associated factors of current psychological problems were the occupations of physicians or nurses, less than 1 year of experience, university education, living with 4–5 people, reporting 1000–5000 m distance between home and workplace, participating in the COVID-19 control for less than 1 week, being under social isolation at home, being affected a lot by the community, reporting inadequate equipment in current workplace conditions, frequently working in the department directly in contact with the COVID-19 patients, and feeling anxious, stressed, or sad about current works. Present findings can provide valuable evidence for the policymakers and managers to adopt supportive, encouraging, motivational, protective, training, and educational interventions into healthcare workforce in other parts of Vietnam.
    Type of Medium: Online Resource
    ISSN: 2227-9032
    URL: Article
    DOI: 10.3390/healthcare9060718
    Language: English
    Publisher: MDPI AG
    Publication Date: 2021
    detail.hit.zdb_id: 2721009-1
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 2
    Online Resource
    Online Resource
    Novel Ensemble Landslide Predictive Models Based on the Hyperpipes Algorithm: A Case Study in the Nam Dam Commune, Vietnam
    MDPI AG ; 2020
    In:  Applied Sciences Vol. 10, No. 11 ( 2020-05-27), p. 3710-
    Details
    In: Applied Sciences, MDPI AG, Vol. 10, No. 11 ( 2020-05-27), p. 3710-
    Abstract: Development of landslide predictive models with strong prediction power has become a major focus of many researchers. This study describes the first application of the Hyperpipes (HP) algorithm for the development of the five novel ensemble models that combine the HP algorithm and the AdaBoost (AB), Bagging (B), Dagging, Decorate, and Real AdaBoost (RAB) ensemble techniques for mapping the spatial variability of landslide susceptibility in the Nam Dan commune, Ha Giang province, Vietnam. Information on 76 historical landslides and ten geo-environmental factors (slope degree, slope aspect, elevation, topographic wetness index, curvature, weathering crust, geology, river density, fault density, and distance from roads) were used for the construction of the training and validation datasets that are the prerequisites for building and testing the proposed models. Using different performance metrics (i.e., the area under the receiver operating characteristic curve (AUC), negative predictive value, positive predictive value, accuracy, sensitivity, specificity, root mean square error, and Kappa), we verified the proficiency of all five ensemble learning techniques in increasing the fitness and predictive powers of the base HP model. Based on the AUC values derived from the models, the ensemble ABHP model that yielded an AUC value of 0.922 was identified as the most efficient model for mapping the landslide susceptibility in the Nam Dan commune, followed by RABHP (AUC = 0.919), BHP (AUC = 0.909), Dagging-HP (AUC = 0.897), Decorate-HP (AUC = 0.865), and the single HP model (AUC = 0.856), respectively. The novel ensemble models proposed for the Nam Dan commune and the resultant susceptibility maps can aid land-use planners in the development of efficient mitigation strategies in response to destructive landslides.
    Type of Medium: Online Resource
    ISSN: 2076-3417
    URL: Article
    DOI: 10.3390/app10113710
    Language: English
    Publisher: MDPI AG
    Publication Date: 2020
    detail.hit.zdb_id: 2704225-X
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 3
    Online Resource
    Online Resource
    Development, Characterization and In Vitro Evaluation of Paclitaxel and Anastrozole Co-Loaded Liposome
    MDPI AG ; 2020
    In:  Processes Vol. 8, No. 9 ( 2020-09-06), p. 1110-
    Details
    In: Processes, MDPI AG, Vol. 8, No. 9 ( 2020-09-06), p. 1110-
    Abstract: Paclitaxel (PTX) and anastrozole (ANA) have been frequently applied in breast cancer treatment. PTX is well-known for its anti-proliferative effect meanwhile ANA has just been discovered to act as an estrogen receptor α (ERα) ligand. The combination therapy of PTX and ANA is expected to improve treating efficiency, as ANA would act as a ligand binding with the ERα gene expressed in breast cancer cells and thereafter PTX would inhibit the division and cause death to those cancer cells. In this study, liposome-based nanocarriers (LP) were developed for co-encapsulation of PTX and ANA to improve the efficacy of the combined drugs in an Estrogen receptor-responsive breast cancer study. PTX-ANA co-loaded LP was prepared using thin lipid film hydration method and was characterized for morphology, size, zeta potential, drug encapsulation and in vitro drug release. In addition, cell proliferation (WST assay) and IN Cell Analyzer were used for in vitro cytotoxicity studies on a human breast cancer cell line (MCF-7). Results showed that the prepared LP and PTX-ANA-LP had spherical vesicles, with a mean particle size of 170.1 ± 13.5 nm and 189.0 ± 22.1 nm, respectively. Controlled and sustained releases were achieved at 72 h for both of the loaded drugs. The in vitro cytotoxicity study found that the combined drugs showed higher toxicity than each single drug separately. These results suggested a new approach to breast cancer treatment, consisting of the combination therapy of PTX and ANA in liposomes based on ER response.
    Type of Medium: Online Resource
    ISSN: 2227-9717
    URL: Article
    DOI: 10.3390/pr8091110
    Language: English
    Publisher: MDPI AG
    Publication Date: 2020
    detail.hit.zdb_id: 2720994-5
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 4
    Online Resource
    Online Resource
    Kinetic Model of Moisture Loss and Polyphenol Degradation during Heat Pump Drying of Soursop Fruit (Annona muricata L.)
    MDPI AG ; 2022
    In:  Processes Vol. 10, No. 10 ( 2022-10-14), p. 2082-
    Details
    In: Processes, MDPI AG, Vol. 10, No. 10 ( 2022-10-14), p. 2082-
    Abstract: The aim of this study is to investigate the impact of time and temperature of the heat pump drying process of soursop slices at different levels on moisture content and total polyphenol content (TPC). Twelve types of classical kinetic models have been used in this work to describe the suitability of experimental data with models. The conformity is assessed based on statistical values (e.g., coefficient of determination (R2), Chi–square value (X2), etc.). The loss of moisture in the material is described in accordance with Fick’s diffusion law. Value of moisture rate (MR), and effective moisture diffusivities (Deff) have been identified. Experimental results show that MR value depends on the time and drying temperature, Deff increases when increasing the drying temperature from 20–50 °C with values of 1.24 × 10−9, 1.85 × 10−8, 7.69 × 10−8, and 5.54 × 10−7 m/s2. The Singh et al. model is the best option to describe the moisture of the sliced soursop drying process at 30 °C (R2 = 0.97815). The largest TPC decomposition occurs at a temperature of 50 °C. The ability to decompose TPC is proportional to the drying temperature. The TPC decomposition dynamic model follows a first–order reaction when drying at 20 °C with a determinant coefficient R2 = 0.9693.
    Type of Medium: Online Resource
    ISSN: 2227-9717
    URL: Article
    DOI: 10.3390/pr10102082
    Language: English
    Publisher: MDPI AG
    Publication Date: 2022
    detail.hit.zdb_id: 2720994-5
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 5
    Online Resource
    Online Resource
    Photovoltaic Array Reconfiguration under Partial Shading Conditions Based on Short-Circuit Current Estimated by Convolutional Neural Network
    MDPI AG ; 2022
    In:  Energies Vol. 15, No. 17 ( 2022-08-30), p. 6341-
    Details
    In: Energies, MDPI AG, Vol. 15, No. 17 ( 2022-08-30), p. 6341-
    Abstract: Partial shading conditions (PSC) have negative effects on the operation of photovoltaic (PV) systems. In this paper, a PV array reconfiguration method is developed to minimize power losses of PV arrays under partial shading conditions. The proposed reconfiguration method is based on equalizing the reduction of the short-circuit current of the PV modules in the PV array. Eight state-of-the-art Convolutional Neural Network models are employed to estimate the effect of shading on the short-circuit current of a PV module. These models include LeNet-5, AlexNet, VGG 11, VGG 19, Inception V3, ResNet 18, ResNet 34, and ResNet 50. Among eight models, the VGG 19 achieves the best accuracy on 1842 sample images. Therefore, this model is used to estimate the ratio of the actual short-circuit current and the estimated short-circuit current in four studied shading scenarios. This ratio decides the switching rule between PV modules throughout the PV array under PSC. A 2×2 experimental PV array shows that the proposed reconfiguration method improves the output power from 5.81% to 25.19% in four shading patterns. Accordingly, the power losses are reduced from 1.32% to 13.75%. The power improvement and the reduction of power losses of the proposed dynamic PV array reconfiguration system under four case studies demonstrates its effectiveness in addressing the effects of PSC on the PV array.
    Type of Medium: Online Resource
    ISSN: 1996-1073
    URL: Article
    DOI: 10.3390/en15176341
    Language: English
    Publisher: MDPI AG
    Publication Date: 2022
    detail.hit.zdb_id: 2437446-5
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 6
    Online Resource
    Online Resource
    Hexavalent Chromium Inhibited Zebrafish Embryo Development by Altering Apoptosis- and Antioxidant-Related Genes
    MDPI AG ; 2023
    In:  Current Issues in Molecular Biology Vol. 45, No. 8 ( 2023-08-18), p. 6916-6926
    Details
    In: Current Issues in Molecular Biology, MDPI AG, Vol. 45, No. 8 ( 2023-08-18), p. 6916-6926
    Abstract: This study aimed to assess the effects of hexavalent chromium on zebrafish (Danio rerio) embryo development. The zebrafish embryos were treated with solutions containing chromium at different concentrations (0.1, 1, 3.125, 6.25, 12.5, 50, and 100 µg/mL). The development of zebrafish embryos was estimated by the determination of survival rate, heart rate, and the measurement of larvae body length. Real time RT-PCR and Western blot were performed to assess the expression of apoptosis- and antioxidant-related genes. The results showed that the reduced survival rate of zebrafish embryos and larvae was associated with an increase in chromium concentration. The exposure of higher concentrations resulted in a decrease in body length of zebrafish larvae. In addition, a marked increase in heart rate was observed in the zebrafish larvae under chromium treatment, especially at high concentrations. The real-time RT-PCR analysis showed that the transcript expressions for cell-cycle-related genes (cdk4 and cdk6) and antioxidant-related genes (sod1 and sod2) were downregulated in the zebrafish embryos treated with chromium. Western blot analysis revealed the upregulation of Caspase 3 and Bax, while a downregulation was observed in Bcl2. These results indicated that hexavalent chromium induced changes in zebrafish embryo development by altering apoptosis- and antioxidant-related genes.
    Type of Medium: Online Resource
    ISSN: 1467-3045
    URL: Article
    DOI: 10.3390/cimb45080436
    Language: English
    Publisher: MDPI AG
    Publication Date: 2023
    detail.hit.zdb_id: 2090836-2
    SSG: 12
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 7
    Online Resource
    Online Resource
    Effects of Extracellular Vesicles Secreted by TGFβ-Stimulated Umbilical Cord Mesenchymal Stem Cells on Skin Fibroblasts by Promoting Fibroblast Migration and ECM Protein Production
    MDPI AG ; 2022
    In:  Biomedicines Vol. 10, No. 8 ( 2022-07-27), p. 1810-
    Details
    In: Biomedicines, MDPI AG, Vol. 10, No. 8 ( 2022-07-27), p. 1810-
    Abstract: Umbilical cord-derived mesenchymal stem cells (UCMSCs) have been illustrated for their roles in immunological modulation and tissue regeneration through the secretome. Additionally, culture conditions can trigger the secretion of extracellular vesicles (EVs) into extracellular environments with significant bioactivities. This study aims to investigate the roles of three EV sub-populations released by UCMSCs primed with transforming growth factor β (TGFβ) and their capacity to alter dermal fibroblast functions for skin aging. Results show that three EV sub-populations, including apoptotic bodies (ABs), microvesicles (MVs), and exosomes (EXs), were separated from conditioned media. These three EVs carried growth factors, such as FGF-2, HGF, and VEGF-A, and did not express noticeable effects on fibroblast proliferation and migration. Only EX from TGFβ-stimulated UCMSCs exhibited a better capacity to promote fibroblasts migrating to close scratched wounds than EX from UCMSCs cultured in the normal condition from 24 h to 52 h. Additionally, mRNA levels of ECM genes (COL I, COL III, Elastin, HAS II, and HAS III) were detected with lower levels in fibroblasts treated with EVs from normal UCMSCs or TGFβ-stimulated UCMSCs compared to EV-depleted condition. On the contrary, the protein levels of total collagen and elastin released by fibroblasts were greater in the cell groups treated with EVs compared to EV-depleted conditions; particularly elastin associated with TGFβ-stimulated UCMSCs. These data indicate the potential roles of EVs from UCMSCs in protecting skin from aging by promoting ECM protein production.
    Type of Medium: Online Resource
    ISSN: 2227-9059
    URL: Article
    DOI: 10.3390/biomedicines10081810
    Language: English
    Publisher: MDPI AG
    Publication Date: 2022
    detail.hit.zdb_id: 2720867-9
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 8
    Online Resource
    Online Resource
    Assessment of Rainfall Distributions and Characteristics in Coastal Provinces of the Vietnamese Mekong Delta under Climate Change and ENSO Processes
    MDPI AG ; 2020
    In:  Water Vol. 12, No. 6 ( 2020-05-29), p. 1555-
    Details
    In: Water, MDPI AG, Vol. 12, No. 6 ( 2020-05-29), p. 1555-
    Abstract: Rainwater is considered a promising alternative water source for coastal areas where freshwater resources are increasingly under pressure. This study evaluates rain regime characteristics that influence the ability to exploit rainwater in the coastal provinces of the Vietnamese Mekong Delta (VMD). In particular, it considers the impact of climate change and El Niño–Southern Oscillation (ENSO) processes. We analyzed rainfall data from 102 monitoring stations across the VMD from 1989 to 2017. Using statistical methods, we explored (1) characteristics of the rainy season, including the dates of onset and cessation and season length; (2) average rainfall volumes; and (3) the maximum number of consecutive nonrainy days during the rainy season and over the year. We also analyzed changes in these characteristics over time, in parallel with ENSO processes and climate change. Trend lines were determined using nonparametric methods, utilizing Sen’s slope estimation and the Mann–Kendall test. Results showed a tendency for the rainy season to start earlier and end later in the western coastal zone of the study area, with season length gradually decreasing towards the East Sea and inland. The shortest rainy season was found in the estuary zone (in the northeast of the VMD). Rainfall was abundant on the west coast, again diminishing gradually towards the East Sea and inland. Rain was also quite plentiful during four dry season observation months in the study area, but it lacked the predictability needed for effective exploitation. The number of consecutive days without rain averaged 96 annually, with a difference of 29 days between the largest and smallest observations. The difference between the provinces with the longest and shortest periods without rain averaged 41 days. Although the impact of climate change on the rain regime is complex, we can say that the rainy season now tends to start earlier, end later, and be lengthier, though without exhibiting clear trends. ENSO processes significantly impacted rainfall regime characteristics, especially the dates of onset and cessation, and season length.
    Type of Medium: Online Resource
    ISSN: 2073-4441
    URL: Article
    DOI: 10.3390/w12061555
    Language: English
    Publisher: MDPI AG
    Publication Date: 2020
    detail.hit.zdb_id: 2521238-2
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 9
    Online Resource
    Online Resource
    Comparison of Machine Learning Methods for Estimating Mangrove Above-Ground Biomass Using Multiple Source Remote Sensing Data in the Red River Delta Biosphere Reserve, Vietnam
    MDPI AG ; 2020
    In:  Remote Sensing Vol. 12, No. 8 ( 2020-04-23), p. 1334-
    Details
    In: Remote Sensing, MDPI AG, Vol. 12, No. 8 ( 2020-04-23), p. 1334-
    Abstract: This study proposes a hybrid intelligence approach based on an extreme gradient boosting regression and genetic algorithm, namely, the XGBR-GA model, incorporating Sentinel-2, Sentinel-1, and ALOS-2 PALSAR-2 data to estimate the mangrove above-ground biomass (AGB), including small and shrub mangrove patches in the Red River Delta biosphere reserve across the northern coast of Vietnam. We used the novel extreme gradient boosting decision tree (XGBR) technique together with genetic algorithm (GA) optimization for feature selection to construct and verify a mangrove AGB model using data from a field survey of 105 sampling plots conducted in November and December of 2018 and incorporated the dual polarimetric (HH and HV) data of the ALOS-2 PALSAR-2 L-band and the Sentinel-2 multispectral data combined with Sentinel-1 (C-band VV and VH) data. We employed the root-mean-square error (RMSE) and coefficient of determination (R2) to evaluate the performance of the proposed model. The capability of the XGBR-GA model was assessed via a comparison with other machine-learning (ML) techniques, i.e., the CatBoost regression (CBR), gradient boosted regression tree (GBRT), support vector regression (SVR), and random forest regression (RFR) models. The XGBR-GA model yielded a promising result (R2 = 0.683, RMSE = 25.08 Mg·ha−1) and outperformed the four other ML models. The XGBR-GA model retrieved a mangrove AGB ranging from 17 Mg·ha−1 to 142 Mg·ha−1 (with an average of 72.47 Mg·ha−1). Therefore, multisource optical and synthetic aperture radar (SAR) combined with the XGBR-GA model can be used to estimate the mangrove AGB in North Vietnam. The effectiveness of the proposed method needs to be further tested and compared to other mangrove ecosystems in the tropics.
    Type of Medium: Online Resource
    ISSN: 2072-4292
    URL: Article
    DOI: 10.3390/rs12081334
    Language: English
    Publisher: MDPI AG
    Publication Date: 2020
    detail.hit.zdb_id: 2513863-7
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 10
    Online Resource
    Online Resource
    An Evaluation of Programmatic Community-Based Chest X-ray Screening for Tuberculosis in Ho Chi Minh City, Vietnam
    MDPI AG ; 2020
    In:  Tropical Medicine and Infectious Disease Vol. 5, No. 4 ( 2020-12-10), p. 185-
    Details
    In: Tropical Medicine and Infectious Disease, MDPI AG, Vol. 5, No. 4 ( 2020-12-10), p. 185-
    Abstract: Across Asia, a large proportion of people with tuberculosis (TB) do not report symptoms, have mild symptoms or only experience symptoms for a short duration. These individuals may not seek care at health facilities or may be missed by symptom screening, resulting in sustained TB transmission in the community. We evaluated the yields of TB from 114 days of community-based, mobile chest X-ray (CXR) screening. The yields at each step of the TB screening cascade were tabulated and we compared cohorts of participants who reported having a prolonged cough and those reporting no cough or one of short duration. We estimated the marginal yields of TB using different diagnostic algorithms and calculated the relative diagnostic costs and cost per case for each algorithm. A total of 34,529 participants were screened by CXR, detecting 256 people with Xpert-positive TB. Only 50% of those diagnosed with TB were detected among participants reporting a prolonged cough. The study’s screening algorithm detected almost 4 times as much TB as the National TB Program’s standard diagnostic algorithm. Community-based, mobile chest X-ray screening can be a high yielding strategy which is able to identify people with TB who would likely otherwise have been missed by existing health services.
    Type of Medium: Online Resource
    ISSN: 2414-6366
    URL: Article
    DOI: 10.3390/tropicalmed5040185
    Language: English
    Publisher: MDPI AG
    Publication Date: 2020
    detail.hit.zdb_id: 2934690-3
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...