Keywords:
Respiratory organs—Diseases.
;
Immunology.
;
Immunogenetics.
;
Human physiology.
;
Respiratory organs
Description / Table of Contents:
Introduction Part I -- The spectrum of asthma epidemiology -- Disease prevalence and burden -- Climate considerations in asthma and impacts of climate change -- Asthma across the ages: children, women, and the elderly -- Asthma as a systemic disease: neurologic, cardiac and metabolic changes in asthma -- Social determinants of health in asthma -- Part II. Mechanistic heterogeneity in asthma, -Phenotypes and endotypes -- Heterogeneity of treatment response to asthma (including mild-moderate asthma) -- Regional airway involvement: Imaging heterogeneity in ventilation, mucus and remodeling -- Biobehavioral determinants of asthma, including CNS influences and dietary/nutrition -- Integrative/ Systems levels studies -- Part III. Severe and difficult to treat asthma endotypes -- Definition, phenotyping of severe asthma, including cluster analysis -- Asthma exacerbations: patient features and potential long-term implications -- Innate inflammation driven remodeling -- Adaptive immunity and remodeling -- Part IV. Influence of heterogeneity on approaches to management -- Approaches to management of asthma -- Guidelines for stepped care and self-monitoring -- Global considerations in asthma treatment - management in low resource settings -- Update on biomarker-driven approaches and precision medicine- adaptive clinical trials e.g., PRECISE -- Conclusion and future directions.
Type of Medium:
Online Resource
Pages:
1 Online-Ressource(X, 418 p. 71 illus., 55 illus. in color.)
Edition:
1st ed. 2023.
ISBN:
9783031322594
Series Statement:
Advances in Experimental Medicine and Biology 1426
URL:
https://doi.org/10.1007/978-3-031-32259-4
DOI:
10.1007/978-3-031-32259-4
Language:
English
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