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  • 2020-2023  (6)
  • 1975-1979  (197)
  • 1
    Online Resource
    Online Resource
    Advances in Protein Chemistry. (1977)
    San Diego :Elsevier Science & Technology,
    Details
    Keywords: Proteins -- Denaturation. ; Tobacco mosaic virus. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (459 pages)
    Edition: 1st ed.
    ISBN: 9780080582047
    Series Statement: Issn Series
    URL: https://ebookcentral.proquest.com/lib/geomar/detail.action?docID=403582
    DDC: 574.87
    Language: English
    Note: Front Cover -- Advances in Protein Chemistry, Volume 31 -- Copyright Page -- Contents -- Contributors to Volume -- Chapter 1. The ε-(γ-GlutamyI) lysine Crosslink and the Catalytic Role of Transglutaminases -- I. Introduction -- II. Historical -- III. Occurrence of the ε(γ-GlutamyI)lysine Crosslink -- IV. Enzymic Formation of the ε-(γ-Glutamyl) lysine Crosslink -- V. Transglutaminases Involved in Formation of the ε-(γ-GlutamyI) lysine Crosslink -- VI. Transglutaminases That Preumably Catalyze Formation of the e-(y-GlutamyI) lysine Crosslink -- VI. Transglutaminases That Presumably Catalyze Formation of the ε-(γ-GlutamyI) lysine Crosslink -- VII. Characteristics Conferred by the E-(y-GlutamyI) lysine Crosslink -- VIII. Catabolism of the e(y-GlutamyI) lysine Crosslink -- IX. Concluding Remarks -- References -- Chapter 2. Thin Film Dialysis -- I. Introduction -- II. Theory of Dialysis -- III. Experimental Methods -- IV. Applications of Thin Film Dialysis -- V. Horizons in Thin Film Dialysis -- References -- Chapter 3. Tobacco Mosaic Virus Protein Aggregation and the Virus Assembly -- I. Introduction -- II. Structure -- III. Functional Design of the Virus -- IV. Protein Aggregation -- V. Nucleation of Assembly -- VI. Rod Elongation -- VII. Selectivity for Viral RNA -- VIII. General Considerations -- Note Added in Proof -- References -- Chapter 4. The Plasma Lipoproteins -- I. Introduction -- II. Classification of the Plasma Lipoproteins -- III. Molecular Properties of Apolipoproteins -- IV. Molecular Organization of Lipoprotein Particles -- V. Lipoprotein Metabolism -- VI. Summary -- References -- Chapet 5. Nerve Growth Factor -- I. Introduction -- II. Nerve Growth Factor from Mouse Submaxillary Gland -- III. The High Molecular Weight Form of NGF (7 S NGF) -- IV. The Biosynthesis of NGF -- V. Snake Venom NGF -- VI. The Mechanism of Action of NGF. , VII. Conclusion -- References -- Author Index -- Subject Index -- Cumulative Author Index, Volumes 22-31 -- Cumulative Title Index, Volumes 22-31 -- Contents of Previous Volumes.
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  • 2
    Online Resource
    Online Resource
    Advances in Radiation Biology : Volume 8. (1979)
    Saint Louis :Elsevier Science & Technology,
    Details
    Keywords: Radiobiology. ; Electronic books.
    Description / Table of Contents: Advances in Radiation Biology, Volume 8, provides an overview of the state of knowledge in the field of radiation biology. The book contains nine chapters and opens with a study on aspects of oxygen enhancement ratio and relative biological effectiveness that are relevant to neutron therapy. This is followed by separate chapters on the clinical application of negative pi mesons; the clinical features and cellular and biochemical defects in human diseases, with an emphasis on defects in DNA metabolism, particularly DNA repair; recombination in eukaryotes; and the principal mechanisms of DNA damage and repair in higher plants. Subsequent chapters deal with the effect of oxygen on the repair of radiation damage by cells and tissues; the effects of ionizing radiation on mammalian cells; heritable lesions affecting populations of irradiated mammalian cells; and environmental impact of tritium.
    Type of Medium: Online Resource
    Pages: 1 online resource (480 pages)
    Edition: 1st ed.
    ISBN: 9781483281902
    URL: https://ebookcentral.proquest.com/lib/geomar/detail.action?docID=1598233
    DDC: 574.19/15
    Language: English
    Note: Front Cover -- Advances in Radiation Biology -- Copyright Page -- Table of Contents -- Contributors -- Contents of Other Volumes -- Chapter 1. Aspects of OER and RBE Relevant to Neutron Therapy -- I. Introduction -- II. Early Studies -- III. The Rationale for Fast Neutron Therapy -- IV. The Oxygen Effect -- V. Repair after X Rays and Neutrons -- VI. Relative Biological Effectiveness (RBE) for Normal Tissues -- VII. Mixtures of Neutrons and X Rays -- VIII. Responses of Tumors -- IX. Clinical Results -- X. Conclusions -- Chapter 2. Present Status of the Proposed Use of Negative Pi Mesons in Radiotherapy -- I. Introduction -- II. The Pion Proposal -- III. Single-Cell Survival -- IV. Somatic-Cell Mutagenesis Studies -- V. Multicellular Tumor Spheroid Studies -- VI. Normal versus Tumor Tissue Responses in the Laboratory -- VII. Normal versus Tumor Tissue Responses in the Clinic -- VIII. Summary -- Chapter 3. Human Diseases Associated with Defective DNA Repair -- I. Introduction -- II. Xeroderma Pigmentosum -- III. Ataxia Telangiectasia (Louis-Bar Syndrome) -- IV. Fanconi's Anemia -- V. The Hutchinson-Gilford Progeria Syndrome -- VI. Bloom's Syndrome -- VII. Cockayne's Syndrome -- VIII. Down's Syndrome (Trisomy 21) -- IX. Retinoblastoma -- X. Chronic Lymphocytic Leukemia -- XI. Miscellaneous Human Diseases with Possible DNA Repair Defects -- XII. Conclusions -- Chapter 4. The Induction of Molecular and Genetic Recombination in Eukaryotic Cells -- I. Introduction -- II. Meiotic Recombination in General -- III. Mitotic Recombination -- IV. Mechanisms of Induced Mitotic Recombination -- V. The Relation between Induced Recombination in Lower and Higher Eukaryotes -- VI. Concluding Comments -- Chapter 5. DNA Damage and Repair in Higher Plants1 -- I. Introduction -- II. Some Features of Injury of Plants and Plant DNA by Radiation and Chemical Treatments. , III. Principal Ways of Repair of DNA Damage -- IV. Initial Approaches to the Study of Repair in Higher Plants -- V. Photoreactivation in Higher Plants -- VI. Excision Repair of Damage Induced in Plant DNA with UV-lrradiation -- VII. Repair of Damage Induced in Plant DNA with Ionizing Radiation -- VIII. Repair of Damage Induced in Plant DNA with Chemical Mutagens and Carcinogens -- IX. Inhibition of Repair Processes in Higher Plants -- X. Repair and Mutagenesis -- XI. Concluding Remarks -- Chapter 6. The Effect of Oxygen on the Repair of Radiation Damage by Cells and Tissues1 -- I. Introduction -- II. Important Aspects of the Oxygen Effect -- III. Repair in Vitro -- IV. Repair in Vivo -- V. Repair of Molecular Damage -- Chapter 7. Manifestations of Damage from Ionizing Radiation in Mammalian Cells in the Postirradiation Generations -- I. Introduction -- II. Cellular Effects -- III. Subcellular Effects: Chromosome Aberrations -- IV. Effects on the Synthesis of Macromolecules -- V. Relation of the Behavior of Cells in the Postirradiation Generations to Cell Death -- Chapter 8. Heritable Lesions Affecting Proliferation of Irradiated Mammalian Cells1 -- I. Introduction -- II. Early Observations -- III. Basic Techniques in the Study of Heritable Lesions -- IV. Heritably Damaged Cells -- V. Induction of Heritable Lesions by Densely Ionizing Radiations -- VI. Induction of Heritable Lesions by Tritiated Compounds -- VII. The Oxygen Effect -- VIII. Induction of Heritable Lesions by Alkylating Agents and Other Factors -- IX. Observations in Vivo -- X. Heritable Lesions and Survival Determination -- XI. Late Recovery -- XII. Quantification of Heritably Damaged Cells on the Basis of Growth Observations -- XIII. Postirradiation Intrapopulation Disturbances and Recovery -- XIV. Conjectures as to the Nature of Heritable Lesions and the Mechanisms of Late Recovery. , XV. Significance for Radiotherapy -- XVI. Summary and Future Objectives -- Chapter 9. Tritium in the Environment1 -- I. Introduction -- II. Physical Characteristics -- III. Sources of Tritium -- IV. World Tritium Inventory -- V. Metabolism of Tritium: Intake and Distribution -- VI. Isotopic Effects and Transmutation -- VII. Dosimetry of Tritium -- VIII. Population Exposure to Tritium and Related Risks -- IX. Summary -- Subject Index.
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  • 3
    Online Resource
    Online Resource
    Advances in Radiation Biology : Volume 6. (1976)
    Saint Louis :Elsevier Science & Technology,
    Details
    Keywords: Radiobiology. ; Electronic books.
    Description / Table of Contents: Advances in Radiation Biology, Volume 6, provides an overview of the state of knowledge in the field of radiation biology. The book contains eight chapters and opens with a study on the nature of radiation effects on nucleic acid metabolism in mammalian cells. This is followed by separate chapters on the nature of UV effects on transcriptional functions; interrelationships between ionizing radiation, protein synthesis, and the physiological expressions of radiation damage; and correlation of DNA repair activities and cellular effects in irradiated mammalian cells. Subsequent chapters deal with the interaction of heat and radiation on an in vitro and an in vivo system; the role of hyperthermia for cancer therapy; thermal potentiation of mammalian cell killing; and autologous stem-cell banks for restoring hemopoiesis.
    Type of Medium: Online Resource
    Pages: 1 online resource (357 pages)
    Edition: 1st ed.
    ISBN: 9781483281926
    URL: https://ebookcentral.proquest.com/lib/geomar/detail.action?docID=1604056
    DDC: 574.19/15
    Language: English
    Note: Front Cover -- Advances in Radiation Biology -- Copyright Page -- Table of Contents -- Contributors -- CONTENTS OF OTHER VOLUMES -- Chapter 1. Effects of Ionizing Radiation on Nucleic Acid Synthesis in Mammalian Cells -- I. Introduction -- II. Effects of Radiation on the DNA Synthetic Period -- III. Radiation Effects on DNA Precursor Metabolism and DNA Synthesis -- IV. Possible Mechanisms Assobnbgciated with Radiation-Induced Depression of DNA Synthesis -- V. Ionizing Radiation and RNA Metabolism in the Cultured Mammalian Cell -- REFERENCES -- Chapter 2. UV Damage at the Transcriptional Level -- I. Introduction -- II. In Vitro Transcription of UV-lrradiated DNA Templates -- III. In Vivo Transcription of UV-lrradiated DNA -- IV. RNA Synthesis in UV-lrradiated Bacteria -- V. RNA Synthesis in UV-lrradiated Eukaryotic Cells -- VI. Quantitative Correlation of UV Effects on theTranscriptional Template Functions of DNA -- VII. Nature of Transcription-Terminating UV Lesions -- VIII. Investigating Transcriptional Linkage through UV-Induced RNA Chain Termination -- REFERENCES -- Chapter 3. Interrelationships between Ionizing Radiation, Protein Synthesis, and the Physiological Expressions of Radiation Damage -- I. Introduction -- II. Interrelationships between Protein Synthesis and the Physiological Expression of Radiation Damage -- III. Alterations in Protein Synthesis -- IV. Conclusions -- ACKNOWLEDGMENTS -- REFERENCES -- Chapter 4. Role of DNA Repair in Cell Inactivation, Aging, and Transformation: A Selective Review, A Speculative Model -- I. Introduction -- II. DNA Repair in Irradiated Mammalian Cells -- III. Effects of Radiation in Mammalian Cells -- IV. A Model for Correlation of DNA Repair Activities and Cellular Effects in Irradiated Mammalian Cells -- REFERENCES. , Chgapter 5. Response of Cells In Vitro and Tissues In Vivo to Hyperthermia and X-lrradiation -- I. Introduction -- II. Effect of Hyperthermia Alone in Vitro -- III. Effect of Hyperthermia Plus Radiation in Vitro -- IV. Effect of Hyperthermia Alone in Vivo -- V. Effect of Hyperthermia and Radiation in Vivo -- VI. Discussion -- VII. Summary -- REFERENCES -- Chapter 6. Experimental and Clinical Aspects of Hyperthermia Applied to the Treatment of Cancerwith Special Reference to the Roleof Ultrasonic and Microwave Heating -- I. Introduction -- II. Methods of Inducing Hyperthermia -- III. Mechanisms of Action -- IV. Effects of Hyperthermia Alone -- V. Effects of Hyperthermia with Radiation -- VI. Effects of Hyperthermia with Chemotherapy -- VII. Microwaves in Cancer Therapy -- VIM. Ultrasound in Cancer Therapy -- IX. General Summary and Conclusions -- ACKNOWLEDGMENTS -- REFERENCES -- Chapter 7. Thermal Potentiation of Mammalian Cell Killing: Clues for Understanding and Potential for Tumor Therapy -- I. Introduction -- II. Effect of Heat Alone on Cells -- III. Theoretical Framework for Thermaland Radiation Experiments -- IV. Thermal Potentiation of Cell Killing -- V. DNA, Strand Breaks, Thermal Effects, and Repair -- VI. Remarks on Thermal Potentiation in Tumor Systems -- VII. Summary8 -- VIII. Conclusion -- Appendix -- ACKNOWLEDGEMENTS -- REFERENCES -- Chapter 8. Autologous Stem-Cell Banksfor Restoring Hemopoiesis -- I. Introduction -- II. Treating the Hemopoietic Syndrome -- III. Stem Cells in Blood -- IV. Cryopreservation -- V. Feasibility -- VI. Summary -- ACKNOWLEDGMENTS -- REFERENCES -- Subject Index.
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  • 4
    Online Resource
    Online Resource
    Advances in Protein Chemistry. (1979)
    San Diego :Elsevier Science & Technology,
    Details
    Keywords: Proteins. ; Immune complexes. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (327 pages)
    Edition: 1st ed.
    ISBN: 9780080582061
    Series Statement: Issn Series
    URL: https://ebookcentral.proquest.com/lib/geomar/detail.action?docID=403584
    DDC: 574.87
    Language: English
    Note: Front Cover -- Advances in Protein Chemistry, Volume 33 -- Copyright Page -- Contents -- Contributors to Volume 33 -- Chapter 1. Activation of the Complement System by Antibody-Antigen Complexes: The Classical Pathway -- I. Introduction -- II. Structure of the Early Components of the Classical Pathway -- III. Assembly and Activation of the Complement Components on Cell-Bound and Aggregated Antibody -- IV. Control Proteins Associated with Components C1 to C5 -- V. Biosynthesis of the Early Components of Complement -- VI. Conclusions -- References -- Addendum -- Chapter 2. Motions in Proteins -- I. Introduction -- II. Packing Density and Structural Stability -- III. Solvent Exchange -- IV. Fluorescence and Absorbance Spectroscopy -- V. Nuclear Magnetic Resonance Spectroscopy -- VI. Dynamics of the Crystalline State -- VII. Significance of Motions in Proteins -- References -- Chapter 3. Stability of Proteins -- I. Introduction -- II. Temperature-Induced Changes in Protein -- III. Thermodynamic Presentation of Protein -- IV. Thermodynamics of the Denaturant Action on Protein -- V. Thermodynamics of Protein Unfolding -- VI. Thermodynamic Properties of Protein -- References -- Chapter 4. Peptides of the Central Nervous System -- I. Introduction -- II. Individual Neuropeptides -- III. Conclusions -- References -- Author Index -- Subject Index -- Contents of Previous Volumes.
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  • 5
    Online Resource
    Online Resource
    Advances in Radiation Biology : Volume 7. (1978)
    Saint Louis :Elsevier Science & Technology,
    Details
    Keywords: Nuclear medicine. ; Quality of life. ; Radiobiology. ; Electronic books.
    Description / Table of Contents: Advances in Radiation Biology, Volume 7, provides an overview of the state of knowledge in the field of radiation biology. The book contains six chapters and opens with a study on the exploitation of the unique properties of purified lesion-recognizing enzymes as the basis of assays that monitor the repair of DNA lesions in vivo. This is followed by separate chapters on the effects of radiation on living eukaryotic cells; the ecological effects of ionizing radiation; and the applicability of bacterial models of DNA repair and recovery to UV-irradiated mammalian cells. Subsequent chapters focus on acute radiation effects on the adult nervous system and the repair of DNA modified by cytotoxic, mutagenic, and carcinogenic chemicals.
    Type of Medium: Online Resource
    Pages: 1 online resource (461 pages)
    Edition: 1st ed.
    ISBN: 9781483281919
    Series Statement: Serial Publication
    URL: https://ebookcentral.proquest.com/lib/geomar/detail.action?docID=1643480
    DDC: 574.19/15
    Language: English
    Note: Front Cover -- Advances in Radiation Biology -- Copyright Page -- Table of Contents -- Contributors -- Preface -- Contents of Other Volumes -- Chapter 1. Use of Purified Lesion-Recognizing Enzymes to Monitor DNA Repair in Vivo -- I. Introduction -- II. Enzymatic Repair Mechanisms -- III. Conventional Repair Assays -- IV. Enzymatic Assays -- V. Experimental Applications of Enzymatic Assays -- VI. Compendium of Lesion-Specific Endonucleases -- VII. Concluding Comments and Perspectives -- Note Added in Proof -- ACKNOWLEDGMENTS -- References -- Chapter 2. The Crucial Role of DNA Double-Strand Breaks in Cellular Radiobiological Effects -- I. Introduction -- II. The Basis of the Molecular Theory -- III. Cell Survival -- IV. Chromosomal Aberrations -- V. Somatic Mutations -- VI. Radiation-Induced Malignancy -- VII. Hereditary Effects -- VIII. Summary and Conclusions -- ACKNOWLEDGMENTS -- References -- Chapter 3. Evaluating the Effects of Ionizing Radiation on Aquatic Organisms -- I. Introduction -- II. Dosimetry in the Aquatic Environment -- III. Effects of Ionizing Radiation on Aquatic Invertebrates -- IV. Effects of High-Level Radiation Exposure on Adult Fish -- V. Effects of Acute Irradiation on Teleosts -- VI. Effects of Irradiation on Developing Fish Eggs -- VII. Cytological and Genetic Effects of Irradiation on Aquatic Organisms -- VIII. Effects of Radiation on Natural Populations -- XI. Discussion -- ACKNOWLEDGMENTS -- References -- Chapter 4. Applicability of Bacterial Models of DNA Repair and Recovery to UV-lrradiated Mammalian Cells -- I. Objective of Review -- II. Repair and Recovery in Bacteria -- III. Excision Repair in Mammalian Cells -- IV. DNA Synthesis and Replication -- V. Postreplication Repair -- VI. Summary and Conclusions -- ACKNOWLEDGMENTS -- References. , Chapter 5. Electrophysiological Studies on Radiation-Induced Changes in the Adult Nervous System -- I. Introduction -- II. Physiological Changes in the Nervous System Induced by Ionizing Radiation -- ACKNOWLEDGMENTS -- References -- Chapter 6. The Repair of DNA Modified by Cytotoxic, Mutagenic, and Carcinogenic Chemicals -- Part A. Chemical Modifications to DNA and Their Cytotoxic, Mutagenic, and Carcinogenic Consequences -- I. Introduction -- II. Reactions of Chemicals with Nucleic Acids -- III. Biological Effects of Reactions with DNA -- Part B. Repair of Chemically Modified DNA -- I. Excision Repair -- II. Postreplication Repair -- III. Genetic Factors and DNA Repair -- Part C. Conclusions and Perspectives -- List of Abbreviations -- ACKNOWLEDGMENTS -- References -- Subject Index.
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  • 6
    Online Resource
    Online Resource
    Advances in Protein Chemistry. (1975)
    San Diego :Elsevier Science & Technology,
    Details
    Keywords: Proteins -- Denaturation. ; Proteins. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (333 pages)
    Edition: 1st ed.
    ISBN: 9780080582023
    Series Statement: Issn Series
    URL: https://ebookcentral.proquest.com/lib/geomar/detail.action?docID=403579
    DDC: 574.87
    Language: English
    Note: Front Cover -- Advances in Protein Chemistry, Volume 29 -- Copyright Page -- Contents -- Contributors to Volume 29 -- Chapter 1. Energetics of Ligand Binding to Proteins -- I. Introduction -- II. Multiple Ligand Binding by Proteins -- III. Binding by Multimer Proteins -- IV. Extension of the Concept of Ligand Interaction to Covalent Bond Exchange in Proteins -- V. Cooperativity and Ligand Correlation -- VI. Biological Specificity and Ligand Binding -- Appendix -- References -- Chapter 2. Avidin -- I. Introduction -- II. Purification and Covalent Chemistry -- III. Physical Properties -- IV. Binding Properties -- V. Subunit Structure -- VI. Miscellaneous Topics -- References -- Chapter 3. Carbonyl-Amine Reactions in Protein Chemistry -- I. Introduction -- II. The Chemistry of Carbonyl Groups, of Amino Groups, and of the Carbonyl-Amine Reaction -- III. Reaction of Carbonyl Compounds with Amino Acids and Proteins -- IV. The Carbonyl-Amine Reaction in Biological Processes -- V. Naturally Occurring Deteriorative Reactions -- VI. Commercial Applications. -- References -- Chapter 4. Experimental and Theoretical Aspects of Protein Folding -- I. Introduction -- II. Spontaneous Folding of Proteins -- III. In Vitro Complementation of Protein Fragments -- IV. Flexibility of Proteins in Solution: Effect of Cross-Links and Ligands -- V. Synthetic Analogs of Proteins -- VI. Folding of Fibrous Proteins -- VII. Experimental Approaches to the Study of Conformation -- VIII. Energetic Factors Determining Protein Folding -- IX. Concluding Remarks -- References -- Note Added in Proof -- Author Index -- Subject Index -- Contents of Previous Volumes.
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  • 7
    Online Resource
    Online Resource
    Advances in Protein Chemistry. (1976)
    San Diego :Elsevier Science & Technology,
    Details
    Keywords: Proteins. ; Repressors, Genetic. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (501 pages)
    Edition: 1st ed.
    ISBN: 9780080582030
    Series Statement: Issn Series
    URL: https://ebookcentral.proquest.com/lib/geomar/detail.action?docID=403581
    DDC: 574.87
    Language: English
    Note: Front Cover -- Advances in Protein Chemistry, Volume 30 -- Copyright Page -- Contents -- Contributors to Volume 30 -- Chapter 1. Repressors -- I. Introduction -- II. Protein Chemistry of the lac Repressor -- III. DNA and Effector Binding of Repressors -- IV. Analysis of Repressor Gene Mutants -- V. Operators and Promoters -- VI. Models for Repressor-Operator Interactions -- References -- Chapter 2. Bovine Liver Glutamate Dehydrogenase -- Dedication -- I. Introduction -- II. The Catalytic Reaction of Glutamate Dehydrogenase -- III. The Interaction of Coenzymes and Purine Nucleotides with Glutamate Dehydrogenase -- IV. Chemical Modifications -- V. Solution Studies -- VI. Ultrastructure of Glutamate Dehydrogenase -- Note Added in Proof -- References -- Chapter 3. The Thermodynamic Basis of the Stability of Proteins, Nucleic Acids, and Membranes -- I. Introduction -- II. Nonpolar Model Compounds -- III. Membrane Model Compounds -- IV. Proteins -- V. Nucleic Acid Model Compounds -- VI. Nucleic Acids -- VII. Discussion -- VIII. Concluding Remarks -- Appendix: Estimation of the Heat-Capacity Change for the Denaturation of Proteins -- References -- Chapter 4. Membrane Receptors and Hormone Action -- I. Introduction -- II. Relation between Biological Activity and Binding -- III. Physicochemical Detection and Assay of Receptors -- IV. Solubilization of Membrane Receptors -- V. Examples of Membrane-Localized Receptors -- VI. Affinity Techniques, Polyvalent Hormone Derivatives, and Receptor Studies -- VII. Theoretical Mechanisms of Hormone-Receptor Binding and Action -- VIII. Summary -- References -- Author Index -- Subject Index -- Contents of Previous Volumes.
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  • 8
    Online Resource
    Online Resource
    Advances in Protein Chemistry. (1978)
    San Diego :Elsevier Science & Technology,
    Details
    Keywords: Proteins. ; Immunoglobulins. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (356 pages)
    Edition: 1st ed.
    ISBN: 9780080582054
    Series Statement: Issn Series
    URL: https://ebookcentral.proquest.com/lib/geomar/detail.action?docID=403583
    DDC: 574.87
    Language: English
    Note: Front Cover -- Advances in Protein Chemistry, Volume 32 -- Copyright Page -- Contents -- Contributors to Volume 32 -- Chapter 1. The Structural Basis of Antibody Complementarity -- I. Introduction -- II. Immunochemical Studies of the Size and Shape of Antibody Combining Sites -- III. Fragments, Chains, and Domains of Immunoglobulins and Antibodies -- IV. The Recognition and Role of Variable Regions -- V. Hypervariable Regions or Complementarity- Determining Segments (CDR) -- VI. Correlation of Variability with Physiochemical Properties of Amino Acids in Immunoglobulin Chains -- VII. Affinity Labeling Data and Hypervariable Segments -- VIII. X-Ray Crystallographic Studies on the Combining Sites of Myeloma Proteins -- IX. Predictive Attempts Based on Inserting CDR Sequences upon a Constant Framework -- X. Predictive Attempts Based on Statistical Examinations of Sequences and Distribution of Amino Acids in CDR -- XI. Other Directions -- References -- Chapter 2. Protein Fractionation at Subzero Temperatures -- I. Introduction -- II. The Properties of Aqueous-Organic Mixtures as a Function of Temperature: Physiochemical Data and Their Manipulation -- III. Adaptation of Fractionation Techniques to Subzero Temperatures -- IV. Applications -- V. Conclusions -- Addendum -- References -- Chapter 3. Antifreeze Protein from Fish Bloods -- I. Introduction -- II. Freezing Resistances of Polar Fish Blood Sera -- III. Preparation and Properties of Antifreeze Glycoprotein (AFGP) from Antarctic Fish Bloods -- IV. The Antilectin Activity of AFGP -- V. Effects of AFGP on Freezing -- VI. Activities of Chemical Derivatives of AFGP -- VII. Other Proteins Reported To Have Antifreeze Activity -- VIII. Theoretical Aspects of Actions of Substances Lowering Freezing Temperatures -- IX. Discussions of Models for Mechanism of Action of Antifreeze Systems. , X. Summary and Conclusions -- References -- Note Added in Proof -- Chapter 4. Proteins at Interfaces -- I. Introduction -- II. Experimental Techniques -- III. Kinetics and Mechanism of Adsorption -- IV. Conformation of Protein Molecules at Interfaces -- V. Equilibrium Aspects of Adsorption -- VI. Reactions at Interfaces -- VII. Proteins at Interfaces in Biological Systems -- References -- Author Index -- Subject Index -- Contents of Previous Volumes.
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  • 9
    Book
    Book
    The Sea miners : illustrated with photographs and diagrams (1977)
    New York : Hastings House Publishers
    Details Availability
    Keywords: $erda
    Type of Medium: Book
    Pages: 158 Seiten
    ISBN: 0803867239
    Language: English
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  • 10
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    Origin of interannual variability in global mean sea level (2020)
    National Academy of Sciences
    Details
    Publication Date: 2022-10-26
    Description: Author Posting. © National Academy of Sciences, 2020. This article is posted here by permission of National Academy of Sciences for personal use, not for redistribution. The definitive version was published in Proceedings of the National Academy of Sciences of the United States of America 117(25), (2020): 13983-13990, doi: 10.1073/pnas.1922190117.
    Description: The two dominant drivers of the global mean sea level (GMSL) variability at interannual timescales are steric changes due to changes in ocean heat content and barystatic changes due to the exchange of water mass between land and ocean. With Gravity Recovery and Climate Experiment (GRACE) satellites and Argo profiling floats, it has been possible to measure the relative steric and barystatic contributions to GMSL since 2004. While efforts to “close the GMSL budget” with satellite altimetry and other observing systems have been largely successful with regards to trends, the short time period covered by these records prohibits a full understanding of the drivers of interannual to decadal variability in GMSL. One particular area of focus is the link between variations in the El Niño−Southern Oscillation (ENSO) and GMSL. Recent literature disagrees on the relative importance of steric and barystatic contributions to interannual to decadal variability in GMSL. Here, we use a multivariate data analysis technique to estimate variability in barystatic and steric contributions to GMSL back to 1982. These independent estimates explain most of the observed interannual variability in satellite altimeter-measured GMSL. Both processes, which are highly correlated with ENSO variations, contribute about equally to observed interannual GMSL variability. A theoretical scaling analysis corroborates the observational results. The improved understanding of the origins of interannual variability in GMSL has important implications for our understanding of long-term trends in sea level, the hydrological cycle, and the planet’s radiation imbalance.
    Description: The research was carried out at JPL, California Institute of Technology, under a contract with NASA. This study was funded by NASA Grants NNX17AH35G (Ocean Surface Topography Science Team), 80NSSC17K0564, and 80NSSC17K0565 (NASA Sea Level Change Team). The efforts of J.T.F. in this work were also supported by NSF Award AGS-1419571, and by the Regional and Global Model Analysis component of the Earth and Environmental System Modeling Program of the US Department of Energy's Office of Biological & Environmental Research via National Science Foundation Grant IA 1844590. C.G.P. was supported by the J. Lamar Worzel Assistant Scientist Fund and the Penzance Endowed Fund in Support of Assistant Scientists at the Woods Hole Oceanographic Institution.
    Description: 2020-12-08
    Keywords: Sea level ; Climate variability ; Global mean sea level ; Satellite altimetry
    Repository Name: Woods Hole Open Access Server
    Type: Article
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