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  • 1
    ISSN: 1365-2516
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary.  The international MRI expert subgroup of the International Prophylaxis Study Group (IPSG) has developed a consensus for magnetic resonance imaging (MRI) scales for assessment of haemophilic arthropathy. A MRI scoring scheme including a 10 step progressive scale and a 20 step additive scale with identical definitions of mutual steps is presented. Using the progressive scale, effusion/haemarthrosis can correspond to progressive scores of 1, 2, or 3, and synovial hypertrophy and/or haemosiderin deposition to 4, 5, or 6. The progressive score can be 7 or 8 if there are subchondral cysts and/or surface erosions, and it is 9 or 10 if there is loss of cartilage. Using the additive scale, synovial hypertrophy contributes 1–3 points to the additive score and haemosiderin deposition contributes 1 point. For osteochondral changes, 16 statements are evaluated as to whether they are true or false, and each true statement contributes 1 point to the additive score. The use of these two compatible scales for progressive and additive MRI assessments can facilitate international comparison of data and enhance the accumulation of experience on MRI scoring of haemophilic arthropathy.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1365-2516
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary.  Effective treatment of haemophilic arthropathy requires a detailed evaluation of joint integrity. Methodological assessment of magnetic resonance imaging (MRI) scores are needed to assure reproducibility of measurements when comparing results of clinical trials conducted in different centres. We compared the reliability of two MRI scoring systems for assessment of haemophilic arthropathy: one progressive system that displays the most severe change and one additive system that depicts osteochondral and soft tissue-related changes. A total of 47 1.5 T MRI examinations of knees (n = 21) and ankles (n = 26) of 42 haemophilic boys, age range, 22 months to 18 years, performed at different centres (Toronto, n = 20, Europe, n = 12 and Denver, n = 15) were independently reviewed by four radiologists at two occasions. Twenty-two examinations were from children 〈9 years and 25 from children ≥9. Sagittal and coronal gradient-echo (MPGR, 3D FLASH with fat saturation, GRASS) images were obtained. The MRI examinations of the ankle and knee studies presented with osteochondral abnormalities in 38.5% and 23.8% of the cases respectively. The two scoring systems demonstrated an excellent inter-reader [progressive, 0.88; additive (A, e, s and h components), 0.86] and intra-reader [progressive, 0.92; additive (A, e, s and h components), 0.93] reliability using intraclass correlation coefficients (ICCs). Although ICCs were slightly higher for knees when compared with ankles, and for older children when compared with younger children, all values fell within excellent inter- and intra-reader reliability categories. The two MRI scoring systems demonstrated a comparable reliability. This result constitutes the basis for further development of a combined MRI scoring system for assessment of haemophilic arthropathy, which incorporates progressive and additive components.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1365-2494
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: The botanical composition, intake and digestibility of the diet consumed by 1-year-old weaner sheep grazing a native white grass plant community in the Falkland Islands was measured in five periods between June 1998 and March 1999. Five different sheep were used in each period. Two methods were used for estimating the botanical composition of the diet: plant cuticle patterns in the faeces of the sheep and the patterns of concentrations of n-alkanes in the faeces of sheep. These methods were used to predict the concentrations of C32- and C33-alkanes in the herbage to allow the estimation of herbage intake and digestibility using the n-alkane technique. It was concluded that the n-alkane technique gave more accurate estimates of diet composition based on the comparison with estimates of nutrient intake derived from liveweight gains of sheep. The dominant pasture species, Cortaderia pilosa, was the predominant species consumed during the cooler periods of the year. In the summer, when the highest liveweight gains of sheep occur, the proportion of fine grass species, including Poa spp., Festuca magellanica and Agrostis capillaris, and herbs and sedges in the diet was highest. Herbage intake was the highest during the summer periods when digestibility was also at its peak. Estimated nutritional deficiencies of metabolizable energy, crude protein, phosphorus and vitamin D3 that limit the growth and development of weaner sheep were evident for up to 9 months of the year. Targeted supplementation regimes that counter specific nutrient deficiencies could be developed on the basis of these results to address critical periods in the growth of young sheep.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 445 (2007), S. 399-401 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The upper atmospheres of the four Solar System giant planets exhibit high temperatures that cannot be explained by the absorption of sunlight. In the case of Saturn the temperatures predicted by models of solar heating are ∼200 K, compared to temperatures of ∼400 K ...
    Type of Medium: Electronic Resource
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  • 5
    Publication Date: 2022-05-04
    Description: In northern Italy in 1997, two earthquakes of magnitudes 5.7 and 6 (separated by nine hours) marked the beginning of a sequence that lasted more than 30 days, with thousands of aftershocks including four additional events with magnitudes between 5 and 6. This normal-faulting sequence is not well explained with models of elastic stress transfer1,2, particularly the persistence of hanging-wall seismicity3 that included two events with magnitudes greater than 5. Here we show that this sequence may have been driven by a fluid pressure pulse generated from the coseismic release of a known deep source4 of trapped high-pressure carbon dioxide (CO2). We find a strong correlation between the high-pressure front and the aftershock hypocentres over a twoweek period, using precise hypocentre locations5 and a simple model of nonlinear diffusion. The triggering amplitude (10– 20MPa) of the pressure pulse overwhelms the typical (0.1– 0.2MPa) range from stress changes in the usual stress triggering models1,6. We propose that aftershocks of large earthquakes in such geologic environments may be driven by the coseismic release of trapped, high-pressure fluids propagating through damaged zones created by the mainshock. This may provide a link between earthquakes, aftershocks, crust/mantle degassing and earthquake-triggered large-scale fluid flow.
    Description: Published
    Description: 724-727
    Description: reserved
    Keywords: aftershock ; CO2 ; 04. Solid Earth::04.02. Exploration geophysics::04.02.01. Geochemical exploration
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
    Format: 425100 bytes
    Format: application/pdf
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  • 6
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    In:  [Talk] In: AGU Fall Meeting 2008, 15.-19.12.2008, San Francisco, USA .
    Publication Date: 2012-03-17
    Description: Dimethylsulfide (DMS) eddy correlation air/sea fluxes and gradients were measured aboard the R/V Knorr in January 2006 (Knorr_06). The cruise took place in the Eastern Pacific Ocean, from Manzanillo, Mexico to Punta Arenas, Chile. Atmospheric pressure chemical ionization mass spectrometry was used to measure DMS in air and in air equilibrated with surface seawater using a membrane equilibrator. Gas transfer coefficients (kDMS) computed from the data exhibit a linear dependence on wind speed, over the wind speed range from 1 to 9 m s-1. The k vs U relationship from this study is compared to the results of previous eddy covariance and dual tracer studies and to the NOAA/COARE gas transfer model. The Knorr_06 k values are in good agreement with those derived from earlier DMS flux studies, but differ significantly from prior CO2 data at low wind speeds. The NOAA/COARE model tends to underpredict the wind speed-dependence of kDMS observed on this and previous DMS-based field studies
    Type: Conference or Workshop Item , NonPeerReviewed
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  • 7
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    In:  [Talk] In: AGU Fall Meeting 2005, 05.-09.12.2005, San Francisco, USA .
    Publication Date: 2012-03-17
    Type: Conference or Workshop Item , NonPeerReviewed
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  • 8
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    In:  [Invited talk] In: IFM-GEOMAR, 2008, Kiel, Germany .
    Publication Date: 2012-03-16
    Type: Conference or Workshop Item , NonPeerReviewed
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  • 9
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    In:  [Talk] In: AGU Fall Meeting 2008, 15.-19.12.2008, San Francisco, USA .
    Publication Date: 2012-03-16
    Description: We present eddy covariance based CO2 and DMS fluxes and gas exchange coefficients (piston velocities) measured in situ during a 10-day cruise in the North Atlantic during summer 2007. Most current parameterizations of air/sea gas exchange utilize a generalized piston velocity, k, which relates the gas flux to the air/sea concentration difference, and incorporates all the physical factors controlling gas transport through both sides of the air/sea interface. Tracer release studies have shown that k increases with wind speed, though the functional form of the wind speed-dependence has not been well constrained due to averaging of flux estimates over varying environmental conditions, and also likely due to processes affecting gas exchange that are not correlated to wind speed. During the past decade, the micrometeorological technique eddy covariance (EC) has been used from ships at sea to measure k on short temporal and spatial scales, allowing for measurement of a wide range of environmental conditions on a single expedition. EC- based studies of CO2 and DMS in the Atlantic and Pacific Oceans have clearly shown wind speed dependency of k; however, a wide range of functional relationships is found among the cruises data sets. These differences may reflect differences in physical forcing of gas exchange in different environments, differing behavior of DMS versus CO2 due to solubility, or perhaps methodological differences. The simultaneous measurement of gas transfer coefficients of CO2 and DMS can provide insight into the sensitivity of gas exchange to gas solubility, and the extent to which gas transfer coefficients can be estimated from similarity relationships
    Type: Conference or Workshop Item , NonPeerReviewed
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  • 10
    Publication Date: 2012-03-16
    Type: Conference or Workshop Item , NonPeerReviewed
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