In:
Environmental Toxicology and Chemistry, Wiley, Vol. 34, No. 5 ( 2015-05), p. 1023-1030
Abstract:
The present study investigated the effects of aqueous fullerene suspensions ( n C 60 ) on the bioavailability and toxicity of phenanthrene (Phe) to junior carp ( Cyprinus carpio ). Bioaccumulation factors (BAFs) were calculated based on total as well as free concentrations of Phe. Equal BAF values were obtained with and without n C 60 based on the total concentrations, whereas greater BAFs were found in the presence of n C 60 when free Phe concentrations were applied. The results demonstrated that n C 60 could act as a contaminant carrier to facilitate Phe bioaccumulation. The concentration–response relationship of induced hepatic 7‐ethoxysorufin‐O‐deethylase activity was established in regard to the total and free concentrations of aqueous Phe solutions as well as the body residues. The concentration‐response curves were reliant on the n C 60 concentration when the total concentration of Phe was employed as a variable but were independent of n C 60 presence when free concentration or body residue was employed as a variable, implying that the latter 2 parameters were more accurate in evaluating biological effects. Particles of C 60 were mostly distributed in fish liver and intestines, which indicated the primary routine of uptake was through ingestion. Approximately 22% to 100% of the Phe– n C 60 complex contributed to the bioaccumulation, whereas the complex did not contribute to the toxicity. Environ Toxicol Chem 2015;34:1023–1030. © 2015 SETAC
Type of Medium:
Online Resource
ISSN:
0730-7268
,
1552-8618
Language:
English
Publisher:
Wiley
Publication Date:
2015
detail.hit.zdb_id:
2027441-5
SSG:
12
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