Publication Date:
2015-11-26
Description:
Commentary on: Mansi I, Frei CR, Wang CP, et al. Statins and new-onset diabetes mellitus and diabetic complications: a retrospective cohort study of US healthy adults. J Gen Intern Med 2015 ; 30 : 1599 –610 . Context Statin use is associated with increased incidence of diabetes, and possibly with increased body weight and reduced exercise capacity. Data on the long-term effects of these associations in healthy adults, however, are very limited. Methods This study examined diabetes outcomes among Tricare beneficiaries who were evaluated between 1 October 2003 and 1 March 2012. Participants were divided into statin users and non-users. Patients who, at baseline, had a pre-existing disease indicative of cardiovascular diseases, or any positive element of the Charlson comorbidity index, were excluded. A propensity score, using 42 baseline characteristics, was generated to match statin users and non-users. The main measurements included new-onset diabetes, diabetic complications and overweight/obesity. Findings ...
Keywords:
Health policy, Clinical trials (epidemiology), Epidemiologic studies, Drugs: cardiovascular system, Stroke, Ischaemic heart disease, Diabetes
Print ISSN:
1356-5524
Electronic ISSN:
1473-6810
Topics:
Medicine
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