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  • 2010-2014  (468)
  • 1965-1969
  • 2012  (468)
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  • 2010-2014  (468)
  • 1965-1969
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  • 1
    Online Resource
    Online Resource
    Berkeley :University of California Press,
    Keywords: Electronic books.
    Description / Table of Contents: Declining bird populations, especially those that breed in North American grasslands, have stimulated extensive research on factors that affect nest failure and reduced reproductive success. Until now, this research has been hampered by the difficulties inherent in observing nest activities. Video Surveillance of Nesting Birds highlights the use of miniature video cameras and recording equipment yielding new important and some unanticipated insights into breeding bird biology, including previously undocumented observations of hatching, incubation, fledging, diurnal and nocturnal activity patterns, predator identification, predator-prey interactions, and cause-specific rates of nest loss. This seminal contribution to bird reproductive biology uses tools capable of generating astonishing results with the potential for fresh insights into bird conservation, management, and theory.
    Type of Medium: Online Resource
    Pages: 1 online resource (285 pages)
    Edition: 1st ed.
    ISBN: 9780520954090
    Series Statement: Studies in Avian Biology Series ; v.43
    DDC: 598.07232
    Language: English
    Note: Intro -- Title -- Copyright -- Contents -- Contributors -- Preface -- Foreword -- Part I Synthesis/Overview -- 1 Knowledge Gained from Video-Monitoring Grassland Passerine Nests -- 2 Conservation Implications When the Nest Predators Are Known -- 3 Gamebirds and Nest Cameras: Present and Future -- Part II Breeding Behavior -- 4 Hatching And Fledging Times From Grassland Passerine Nests -- 5 Attendance Patterns And Survival of Western Meadowlark Nests -- 6 Sprague's Pipit Incubation Behavior -- 7 Patterns of Incubation Behavior In Northern Bobwhites -- 8 The Influence of Weather on Shorebird Incubation -- 9 Nocturnal Activity of Nesting Shrubland and Grassland Passerines -- Part III Behavioral Responses to Predation/Predator Identification -- 10 Bird Productivity and Nest Predation In Agricultural Grasslands -- 11 Predatory Identity can Explain Nest Predation Patterns -- 12 Nest Defense: Grassland Bird Responses To Snakes -- 13 Partial Depredations On Northern Bobwhite Nests -- 14 Identification of Sprague's Pipit Nest Predators -- Part IV Technology -- 15 Development of Camera Technology For Monitoring Nests -- Appendix -- Index -- Complete Series List.
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  • 2
    Online Resource
    Online Resource
    Dordrecht :Springer Netherlands,
    Keywords: Human beings-Central nervous system-Communicable diseases. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (261 pages)
    Edition: 1st ed.
    ISBN: 9789401163323
    Series Statement: Neurologic Illness Series
    DDC: 612.82
    Language: English
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  • 3
    Online Resource
    Online Resource
    Hauppauge :Nova Science Publishers, Incorporated,
    Keywords: Geostationary satellites. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (92 pages)
    Edition: 1st ed.
    ISBN: 9781620811344
    Series Statement: Environmental Science, Engineering and Technology
    DDC: 353.00855515000001
    Language: English
    Note: Intro -- ENVIRONMENTAL SATELLITES: FEATURES AND ACQUISITION PLANS -- ENVIRONMENTAL SATELLITES: FEATURES AND ACQUISITION PLANS -- Library of Congress Cataloging-in-Publication Data -- CONTENTS -- PREFACE -- Chapter 1: GEOSTATIONARY OPERATIONAL ENVIRONMENTAL SATELLITES: IMPROVEMENTS NEEDED IN CONTINUITY PLANNING AND INVOLVEMENT OF KEY USERS -- WHY GAO DID THIS STUDY -- WHAT GAO FOUND -- ABBREVIATIONS -- BACKGROUND -- Overview of the GOES-R Program -- Acquisition Strategy -- Program Office Structure -- Prior Report Noted Challenges with Instrument Development and Recommended Steps to Improve Management and Oversight -- GOES-R IS IN DEVELOPMENT, BUT DELAYS IN KEY PROGRAM MILESTONES HAVE ENDANGERED SATELLITE CONTINUITY -- Progress Continues to Be Made on GOES-R Procurement, but Much Work Remains to Be Completed on the Flight and Ground Projects -- Flight Project-Progress Made, but Two Instruments Have Experienced Technical Challenges -- Ground Project-Development Is Under Way, but Important Work Remains to Be Done -- Continued Delays in Launch Dates Put the Continuity of Satellite Operations at Risk -- NOAA HAS NOT ESTABLISHED ADEQUATE CONTINUITY PLANS FOR ITS GEOSTATIONARY SATELLITES -- NOAA'S EFFORTS TO INVOLVE EXTERNAL GOES DATA USERS, PRIORITIZE THEIR DATA NEEDS, AND COMMUNICATE PROGRAM STATUS HAVE SHORTFALLS -- Key GOES Data Users Have Been Identified, but Efforts to Involve Other Federal Agencies and Prioritize Their Data Needs Are Not Sufficient -- NOAA Has Not Effectively Communicated with Other Federal Agencies -- CONCLUSIONS -- RECOMMENDATIONS FOR EXECUTIVE ACTION -- AGENCY COMMENTS -- APPENDIX I: OBJECTIVES, SCOPE, AND METHODOLOGY -- End Notes -- End Notes for Appendix I -- Chapter 2: ENVIRONMENTAL SATELLITES: STRATEGY NEEDED TO SUSTAIN CRITICAL CLIMATE AND SPACE WEATHER MEASUREMENTS -- WHY GAO DID THIS STUDY -- WHAT GAO RECOMMENDS. , WHAT GAO FOUND -- ABBREVIATIONS -- BACKGROUND -- Current Environmental Satellite Programs Include Both Operational and Research Satellites -- Operational Environmental Satellites -- Research Satellites -- Environmental Satellite Data and Products -- An Overview of Climate Products and Uses -- An Overview of Space Weather Products and Uses -- Federal Responsibilities for Environmental Satellites, Satellite Data Processing, and Climate and Space Weather Products -- Climate Responsibilities -- Space Weather Responsibilities -- Interagency Coordination of Satellite-Provided Environmental Observations -- Executive Oversight of Federal Environmental Observations -- Prior GAO Reports Recommended Developing Plans to Restore Cancelled Instruments -- FEDERAL AGENCIES HAVE NOT ESTABLISHED PLANS TO RESTORE ALL CAPABILITIES REMOVED FROM THE NPOESS AND GOES-R PROGRAMS -- Federal Efforts to Ensure the Long-term Provision of Satellite Climate Data Are Insufficient -- FEDERAL AGENCIES LACK A STRATEGY FOR THE LONG-TERM PROVISION OF SPACE WEATHER DATA -- CONCLUSIONS -- Recommendations for Executive Action -- AGENCY COMMENTS AND OUR EVALUATION -- APPENDIX I: OBJECTIVES, SCOPE, AND METHODOLOGY -- APPENDIX II: KEY FEDERAL ORGANIZATIONS WITH CLIMATE AND SPACE WEATHER RESPONSIBILITIES -- APPENDIX III: FEDERAL ORGANIZATIONS THAT PARTICIPATE IN INTERAGENCY COORDINATION GROUPS -- End Notes -- INDEX.
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  • 4
    Online Resource
    Online Resource
    New York :Nova Science Publishers, Incorporated,
    Keywords: Research--United States. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (184 pages)
    Edition: 1st ed.
    ISBN: 9781622570430
    Series Statement: Education in a Competitive and Globalizing World
    DDC: 507.20729999999998
    Language: English
    Note: Intro -- UNITED STATES NATIONAL SCIENCE FOUNDATION FUNCTIONS, FUNDING, AND PROGRAMS -- UNITED STATES NATIONAL SCIENCE FOUNDATION FUNCTIONS, FUNDING, AND PROGRAMS -- CONTENTS -- PREFACE -- Chapter 1 THE U.S. NATIONAL SCIENCE FOUNDATION: AN OVERVIEW -- SUMMARY -- BACKGROUND -- ORGANIZATION AND THE FY2013 REQUEST -- Biological Sciences (BIO) -- Computer and Information Science and Engineering (CISE) -- Engineering (ENG) -- Geosciences (GEO) -- Mathematical and Physical Sciences (MPS) -- Social, Behavioral, and Economic Sciences (SBE) -- Education and Human Resources (EHR) -- OTHER PROGRAM ACTIVITIES AND ACCOUNTS -- Policy Issues -- End Notes -- Chapter 2 EMPOWERING THE NATION THROUGH DISCOVERY AND INNOVATION: NSF STRATEGIC PLAN FOR FISCAL YEARS (FY) 2011-2016 -- I. INTRODUCTION -- NSF Core Values -- II. MISSION -- III. VISION -- IV. PLANNING IN A DYNAMIC ENVIRONMENT -- V. STRATEGIC GOALS AND PERFORMANCE GOALS -- Transform the Frontiers -- Performance Goals -- Innovate for Society -- Performance Goals -- I-1: Make investments that lead to results and resources that are useful to society. -- I-2: Build the capacity of the nation's citizenry for addressing societal challenges through science and engineering. -- I-3: Support the development of innovative learning systems. -- Perform as a Model Organization -- Preformance Goals -- M-1: Achieve management excellence through leadership, accountability, and personal responsibility. -- M-2: Infuse learning as an essential element of the NSF culture with emphasis on professional development and personal growth. -- M-3: Encourage and sustain a culture of creativity and innovation across the agency to ensure continuous improvement and achieve high levels of customer service. -- VI. STRATEGIES AND MEANS -- Core Strategies -- Means for Carrying out Core Strategies -- VII. EVALUATION AND ASSESSMENT. , New Approaches to Evaluation and Assessment -- End Notes -- Chapter 3 AN ANALYSIS OF STEM EDUCATION FUNDING AT THE NSF: TRENDS AND POLICY DISCUSSION -- SUMMARY -- INTRODUCTION -- Methodology, Sources, Data, and Notes -- HISTORICAL FUNDING TRENDS AT NSF -- By Character Class -- By Appropriations Account -- POLICY ISSUES AND OBSERVATIONS -- What Policy Rationale Drives Funding for STEM Education at NSF? -- What Are NSF's STEM Education Activities? -- What Is NSF's Role in the Federal STEM Education Portfolio? -- The Federal STEM Education Effort: Selected Governance Concerns -- Duplication and Consolidation -- A Federal STEM Education Strategy -- What Impact Might Changes in the NSF STEM Education Account Have on Research Activities at NSF? -- OPTIONS FOR CONGRESS -- APPENDIX A. APPROPRIATIONS DATA -- APPENDIX B. CHARACTER CLASS DATA -- End Notes -- Chapter 4 U.S. NATIONAL SCIENCE FOUNDATION: EXPERIMENTAL PROGRAM TO STIMULATE COMPETITIVE RESEARCH (EPSCOR) -- SUMMARY -- BACKGROUND -- EPSCOR GOALS AND MISSION -- OPERATION AND FUNDING -- PROGRAM EFFECTIVENESS -- ISSUES -- CONGRESSIONAL ACTIVITY -- End Notes -- Chapter 5 U.S. NATIONAL SCIENCE FOUNDATION: MAJOR RESEARCH EQUIPMENT AND FACILITY CONSTRUCTION -- SUMMARY -- BACKGROUND -- DEFINITION OF A MAJOR RESEARCH FACILITY -- CONGRESSIONAL HEARING ON PLANNING AND MANAGEMENT ISSUES -- AUDIT OF FUNDING FOR MAJOR RESEARCH EQUIPMENT AND FACILITIES -- CONGRESSIONAL ACTIVITY -- PLANNING AND MANAGEMENT ISSUES -- TERMINATION OF A MAJOR RESEARCH PROJECT -- MREFC SUPPORT IN THE FY2013 BUDGET REQUEST -- APPENDIX -- End Notes -- Chapter 6 HEARING CHARTER FOR ''AN OVERVIEW OF THE NATIONAL SCIENCE FOUNDATION BUDGET FOR FISCAL YEAR 2013'' -- 1. PURPOSE -- 2. WITNESSES -- 3. HEARING OVERVIEW -- NSF Overview -- NSF Budget Summary -- NSF Budget Priorities -- Research and Related Activities (RRA). , Education and Human Resources (EHR) -- Major Research Equipment and Facilities Construction (MREFC) -- Agency Operations and Award Management (AOAM) -- National Science Board (NSB) -- Office of the Inspector General (OIG) -- Interagency Research Activities -- National Nanotechnology Initiative (NNI) -- Networking and Information Technology R& -- D (NITRD) -- U.S. Global Change Research Program (USGCRP) -- APPENDIX A: ONENSF FRAMEWORK PRIORITIES 6 -- End Notes -- Chapter 7 TESTIMONY OF DR. SUBRA SURESH, DIRECTOR, NATIONAL SCIENCE FOUNDATION. HEARING ON ''AN OVERVIEW OF THE NATIONAL SCIENCE FOUNDATION BUDGET FOR FISCAL YEAR 2013'' -- NSF: BUILDING A FOUNDATION FOR SUCCESS -- THE NSF FY 2013 BUDGET REQUEST -- Budget Rationale -- One NSF Framework -- The Intersection of Research and Education -- Continued Investment in American Innovation and Entrepreneurship -- World Class Scientific Infrastructure -- Excellence in Operations -- Efficient Management -- CONCLUSION -- Chapter 8 TESTIMONY OF DR. RAY M. BOWEN, CHAIRMAN, NATIONAL SCIENCE BOARD. HEARING ON ''AN OVERVIEW OF THE NATIONAL SCIENCE FOUNDATION BUDGET FOR FISCAL YEAR 2013'' -- INTRODUCTION -- FISCAL YEAR 2013 BUDGET REQUEST -- U.S. LEADERSHIP IN SCIENCE AND TECHNOLOGY -- PUBLIC RESEARCH UNIVERSITIES AND COLLEGES -- THE GLOBALIZATION OF HIGHER EDUCATION -- NATIONAL SCIENCE BOARD ACTIVITIES -- Merit Review Criteria -- Data Policies -- Instrumentation Report -- Board Involvement in Budget Planning -- CONCLUSION -- Chapter 9 FY 2011 PERFORMANCE AND FINANCIAL HIGHLIGHTS -- WHO WE ARE AND WHAT WE DO -- FROM THE DIRECTOR -- FOLLOWING THE MONEY -- HOW WE ARE DOING: PERFORMANCE HIGHLIGHTS -- MANAGEMENT CHALLENGES -- LOOKING AHEAD: ONENSF -- FY 2011 NSF Executive Staff and Officers -- NSF Officers -- National Science Board Members in FY 2011 -- RESEARCH AND EDUCATION HIGHLIGHTS. , Controlling Machines with Our Minds -- Research Vessel -- Scratch -- End Notes -- INDEX.
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  • 5
    Online Resource
    Online Resource
    Hauppauge :Nova Science Publishers, Incorporated,
    Keywords: Estrogen. ; Estrogen -- Physiological effect. ; Estrogen -- Therapeutic use. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (165 pages)
    Edition: 1st ed.
    ISBN: 9781620817490
    Series Statement: Endocrinology Research and Clinical Developments
    DDC: 615.366
    Language: English
    Note: Intro -- ESTROGENS: BIOCHEMISTRY, THERAPEUTIC USES AND PHYSIOLOGICAL EFFECTS -- ESTROGENS: BIOCHEMISTRY, THERAPEUTIC USES AND PHYSIOLOGICAL EFFECTS -- Library of Congress Cataloging-in-Publication Data -- CONTENTS -- PREFACE -- Chapter 1: ESTROGENS AS MEDIATORS OF OBESITY-INDUCED INFLAMMATION -- ABSTRACT -- ABBREVIATIONS -- ADIPOSE TISSUE-RELATED INFLAMMATION -- ESTROGEN SIGNALING -- ESTROGEN TURNOVER IN THE ADIPOSE TISSUE -- MODELS OF ESTROGEN INSUFFICIENCY -- ESTROGENS AND ADIPOSE TISSUE MASS, DISTRIBUTION AND CELLULARITY -- ESTROGENS AND AT INFLAMMATION -- XENOESTROGENS AND OBESITY-ASSOCIATED COMPLICATIONS -- CONCLUSION -- ACKNOWLEDGMENTS -- REFERENCES -- Chapter 2: EFFECTS OF ESTROGEN USE, FOLLICLE-STIMULATING HORMONE AND LUTEINIZING HORMONE ON COGNITIVE TESTS DEMANDING ATTENTION IN POSTMENOPAUSAL WOMEN -- INTRODUCTION -- METHOD -- Sustained Attention -- Attention Span -- Word Repetition Span -- RESULTS -- CONCLUSION -- AUTHOR CONTRIBUTIONS -- ACKNOWLEDGMENTS -- REFERENCES -- Chapter 3: THE ROLE OF ESTROGENS IN OSTEOARTHRITIS AND INFLAMMATION -- ABSTRACT -- INTRODUCTION -- ESTROGEN RECEPTORS STRUCTURE AND CHARACTERISTICS -- ESTROGEN ON INFLAMMATION -- ESTROGEN AND AUTOIMMUNE DISEASES: RHEUMATOID ARTHRITIS AND SYSTEMIC LUPUS ERYTHEMATOSUS -- ESTROGEN AND OSTEOARTHRITIS -- CONCLUSION -- COMPETING INTERESTS -- REFERENCES -- Chapter 4: ESTROGEN IN REGULATING THE GENDER DISPARITY OF HEPATOCELLULAR CARCINOMA -- ABSTRACT -- INTRODUCTION -- HCC OCCURS PREFERENTIALLY IN MALES,WITH THE SEX DIFFERENCE STARTING FROM CHRONIC HEPATITIS -- THE INVOLVEMENT OF ANDROGEN AXIS IN PROMOTING MALE HCC -- THE INVOLVEMENT OF ESTROGEN AXIS IN PROTECTING FEMALE HCC: EPIDEMIOLOGICAL EVIDENCE AND ANIMAL STUDIES -- WILD TYPE AND VARIANT ESTROGEN RECEPTORSIN NORMAL AND HCC LIVER TISSUES -- MOLECULAR MECHANISMS FOR THE PROTECTIVE ROLE OF ESTROGEN AXIS IN FEMALE HCC. , THE MECHANISMS OF ESTROGEN AXIS IN PREVENTING HEPATIC FIBROSIS AND STEATOSIS -- THE REGULATORY MECHANISMS FOR THE DOWN-REGULATION OF ERa IN FEMALE HCC -- THE INTERACTION BETWEEN THE HEPATITISVIRUS B AND ESTROGEN PATHWAY -- CONCLUSION -- ACKNOWLEDGMENTS -- REFERENCES -- Chapter 5: POST-TRANSCRIPTIONAL EFFECTS OF ESTROGENS ON GENE EXPRESSION: MESSENGER RNA STABILITYAND TRANSLATION REGULATEDBY MICRORNAS AND OTHER FACTORS -- ABSTRACT -- INTRODUCTION -- ESTROGENS STABILIZE AND DESTABILIZESPECIFIC MRNAS -- ESTROGENS AFFECT MRNA TRANSLATION -- ESTROGEN ACTIONS AND MICRORNAS -- MicroRNAs - Biogenesis and Regulation of Gene Expression -- Estrogens Regulate Expression of MicroRNA Genes in Responsive Tissues during Normal Physiology and Disease -- MicroRNAs Regulate ER Gene Expression and Estrogen Actions -- FUTURE THERAPEUTIC APPROACHES TO REGULATINGPOST-TRANSCRIPTIONAL ESTROGEN ACTIONS -- CONCLUSION -- REFERENCES -- INDEX.
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  • 6
    Online Resource
    Online Resource
    Philadelphia :F. A. Davis Company,
    Keywords: Human body -- Popular works. ; Human anatomy -- Popular works. ; Human physiology -- Popular works. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (503 pages)
    Edition: 1st ed.
    ISBN: 9780803638440
    DDC: 612
    Language: English
    Note: Intro -- Copyright -- Preface -- Acknowledgments -- Dedication -- Consultant/Reviewers -- Contents -- Part I: Organization of the Body -- Chapter 1: ORIENTATION TO THE HUMAN BODY -- Organization of the Body -- Organ Systems -- Anatomical Terms -- Directional Terms -- Body Planes -- Body Regions -- Body Cavities -- Abdominal Regions and Quadrants -- Homeostasis -- Homeostatic Regulation -- Review of Key Terms -- Own the Information -- Test Your Knowledge -- Chapter 2: CHEMISTRY OF LIFE -- Basic Structures of Life -- Elements -- Atoms -- Isotopes -- Chemical Bonds -- Basic Processes of Life -- Energy -- Metabolism -- Chemical Reactions -- Compounds of Life -- Inorganic Molecules -- Organic Compounds -- Review of Key Terms -- Own the Information -- Test Your Knowledge -- Chapter 3: CELLS -- Cell Variations -- Cell Structure -- Plasma Membrane -- Nucleus -- Cytoplasm and Organelles -- Cytoskeleton -- Movement Through Cell Membranes -- Passive Transport -- Active Transport -- Cellular Growth and Reproduction -- DNA Structure -- RNA Structure -- Protein Synthesis -- Transcription -- Translation -- Cell Growth and Reproduction -- The Cell Cycle -- Mitosis -- Review of Key Terms -- Own the Information -- Test Your Knowledge -- Part II: Covering, support, and movement of the body -- Chapter 4: TISSUES -- Tissue Development -- Epithelial Tissue -- Classification of Epithelial Tissue -- Connective Tissue -- Components of Connective Tissue -- Types of Connective Tissue -- Nervous Tissue -- Muscle Tissue -- Skeletal Muscle -- Cardiac Muscle -- Smooth Muscle -- Tissue Repair -- Steps in Tissue Repair -- Membranes -- Epithelial Membranes -- Connective Tissue Membranes -- Review of Key Terms -- Own the Information -- Test Your Knowledge -- Chapter 5: INTEGUMENTARY SYSTEM -- Structure of the Skin -- Layers of the Epidermis -- Skin Color. , Functions of the Skin -- Appendages of the Skin -- Hair -- Nails -- Glands -- Review of Key Terms -- Own the Information -- Test Your Knowledge -- Chapter 6: BONES & -- BONE TISSUE -- Bone Functions -- Classification of Bones -- Parts of a Long Bone -- Bone Tissue -- Types of Bone Tissue -- Bone Development Bone Marrow -- Intramembranous Ossification -- Endochondral Ossification -- Bone Remodeling -- Bone Fractures -- Fracture Repair -- Review of Key Terms -- Own the Information -- Test Your Knowledge -- Chapter 7: SKELETAL SYSTEM -- Overview of the Skeletal System -- Bone Surface Markings -- The Adult Skeleton -- Bones of the Skeletal System -- The Skull -- Cranium -- Suture Lines -- Foramen Magnum -- Facial Bones -- Bones Associated with the Skull -- Sinuses -- The Infant Skull -- The Vertebral Column -- Five Sections of the Vertebral Column -- Normal Curvatures of the Spine -- Vertebrae Characteristics -- Intervertebral Disc -- Specialty Vertebrae -- The Thoracic Cage -- Sternum -- Ribs -- Pectoral Girdle -- Upper Limb -- Hand -- Pelvic Girdle -- Pelvis -- Lower Limb -- Femur -- Patella -- Fibula -- Tibia -- Foot and Ankle -- Review of Key Terms -- Own the Information -- Test Your Knowledge -- Chapter 8: JOINTS -- Classifications of Joints -- Fibrous Joints -- Cartilaginous Joints -- Synovial Joints -- Types of Synovial Joints -- Movements of Synovial Joints -- Key Synovial Joints -- Review of Key Terms -- Own the Information -- Test Your Knowledge -- Chapter 9: MUSCULAR SYSTEM -- Types of Muscle -- Cardiac Muscle -- Smooth Muscle -- Skeletal Muscle -- Skeletal Muscle Structure -- Structure of Muscle Fibers -- Muscle Contraction and Relaxation -- How Muscle Fibers Contract -- How Muscle Fibers Relax -- Muscle Tone -- Contraction of an Entire Muscle -- Controlling the Strength of a Contraction -- Isotonic and Isometric Contraction. , Energy Source for Contraction -- Muscle Function -- Superficial Muscles -- How Muscles Are Named -- Muscles of the Head and Neck -- Muscles of the Trunk -- Muscles of the Shoulder and Upper Arm -- Muscles That Move the Forearm -- Muscles of the Wrist and Hand -- Muscles Acting on the Hip and Thigh -- Muscles Acting on the Foot -- Major Muscles of the Body -- Review of Key Terms -- Own the Information -- Test Your Knowledge -- Part III: Regulation and Integration of the body -- Chapter 10: NERVOUS SYSTEM -- Overview of the Nervous System -- Divisions of the Nervous System -- Nervous System Cells -- Neuroglia -- Neurons -- Neuron Structure -- Repair of Nerve Fibers -- Impulse Conduction -- Impulse Conduction in Myelinated Fibers -- Synapses -- Spinal Cord and Somatic Reflexes -- Structure of the Spinal Cord -- Attachment of Spinal Nerves -- Meninges of the Spinal Cord -- Spinal Tracts -- Spinal Nerves -- Categories of Spinal Nerves -- Dermatomes -- Somatic Reflexes -- The Brain and Cranial Nerves -- General Structures of the Brain -- Gray and White Matter -- Meninges of the Brain -- Ventricles -- Cerebrospinal Fluid -- Blood-Brain Barrier -- Divisions of the Brain -- Brainstem -- Cerebellum -- Diencephalon -- Cerebrum -- The Limbic System -- Functions of the Cerebral Cortex -- Motor Functions of the Cerebral Cortex -- Sensory Functions of the Cerebral Cortex -- Language -- Special Senses -- Sleep -- Memory -- Cerebral Lateralization -- Cranial Nerves -- Autonomic Nervous System -- Visceral Reflexes -- Structure of the Autonomic Nervous System -- Divisions of the Autonomic Nervous System -- The Sympathetic Division -- The Parasympathetic Division -- Effects of the ANS on Target Organs -- Neurotransmitters -- Receptors -- Neurotransmitters and Receptors -- Review of Key Terms -- Own the Information -- Test Your Knowledge -- Chapter 11: SENSE ORGANS. , Sensory Receptors -- Classification of Receptors -- The General Senses -- Pain -- Temperature -- Touch -- The Special Senses -- Taste -- Smell -- Hearing -- Balance -- Vision -- Eye Anatomy -- The Process of Vision -- Review of Key Terms -- Own the Information -- Test Your Knowledge -- Chapter 12: ENDOCRINE SYSTEM -- Overview of the Endocrine System -- Comparison of Endocrine and Nervous Systems -- Hormones -- The Pituitary Gland and Hypothalamus -- Anterior Pituitary -- Posterior Pituitary -- Control of Pituitary Secretions -- Pineal Gland -- Thymus -- Thyroid Gland -- Parathyroid Glands -- Calcium Homeostasis -- Adrenal Glands -- Pancreas -- Regulation of Blood Glucose -- Gonads -- Other Endocrine Cells and Chemicals -- Prostaglandins -- Review of Key Terms -- Own the Information -- Test Your Knowledge -- Part IV: Maintenance of the body -- Chapter 13: BLOOD -- Components of Blood -- Blood Cell Formation -- Red Blood Cells -- Hemoglobin -- Life Cycle of Red Blood Cells -- Breakdown of Red Blood Cells -- White Blood Cells -- Granulocytes -- Agranulocytes -- Platelets and the Control of Bleeding -- Hemostasis -- Blood Types -- The Rh Group -- Review of Key Terms -- Own the Information -- Test Your Knowledge -- Chapter 14: HEART -- Structures of the Heart -- The Pericardium -- The Heart Wall -- The Heart Chambers and Great Vessels -- The Heart Valves -- The Heart Skeleton -- Heart Sounds -- Blood Flow Through the Heart -- Coronary Circulation -- Cardiac Conduction -- Electrocardiogram -- Cardiac Cycle -- Cardiac Output -- Heart Rate -- Stroke Volume -- Left Ventricular Failure -- Right Ventricular Failure -- Review of Key Terms -- Own the Information -- Test Your Knowledge -- Chapter 15: VASCULAR SYSTEM -- Vessel Structure -- Arteries -- Conducting Arteries -- Distributing Arteries -- Arterioles -- Veins -- Venules -- Medium-Sized Veins. , Large Veins -- Capillaries -- Capillary Organization -- Capillary Exchange -- Circulatory Routes -- Pulmonary Circulation -- Systemic Circulation -- Principles of Circulation -- Blood Pressure -- Peripheral Resistance -- Venous Return -- Review of Key Terms -- Own the Information -- Test Your Knowledge -- Chapter 16: LYMPHATIC & -- IMMUNE SYSTEMS -- Lymphatic System -- Lymph -- Lymphatic Vessels -- Lymphatic Tissues and Organs -- Overview of the Immune System -- Nonspecific Immunity -- External Barriers -- Phagocytosis -- Antimicrobial Proteins -- Natural Killer Cells -- Inflammation -- Fever -- Specific Immunity -- Lymphocytes -- Antibodies -- Cellular Immunity -- Humoral Immunity -- Immune System Disorders -- Hypersensitivity -- Autoimmune Diseases -- Immunodeficiency Diseases -- Review of Key Terms -- Own the Information -- Test Your Knowledge -- Chapter 17: RESPIRATORY SYSTEM -- Upper Respiratory Tract -- Nose and Nasal Cavities -- Pharynx -- Larynx -- Lower Respiratory Tract -- Trachea -- Bronchial Tree -- Alveoli -- Lungs -- Pulmonary Ventilation -- Respiratory Muscles -- Pressure and Airflow -- Measurements of Ventilation -- Variations in Respiratory Rhythm -- Gas Exchange -- How the Blood Transports Gases -- Review of Key Terms -- Own the Information -- Test Your Knowledge -- Chapter 18: URINARY SYSTEM -- Overview of the Urinary System -- The Kidneys -- Renal Circulation -- Renal Innervation -- Nephron -- Urine Formation -- Glomerular Filtration -- Tubular Reabsorption and Secretion -- Composition of Urine -- Storage and Elimination of Urine -- Ureters -- Urinary Bladder -- Urethra -- Urination -- Review of Key Terms -- Own the Information -- Test Your Knowledge -- Chapter 19: FLUID, ELECTROLYTE, ACID-BASE BALANCE -- Water Balance -- Fluid Compartments -- Balancing Water Gain and Loss -- Regulation of Intake and Output. , Disorders of Water Balance.
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  • 7
    Online Resource
    Online Resource
    Newark :John Wiley & Sons, Incorporated,
    Keywords: Plant-pathogen relationships. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (394 pages)
    Edition: 1st ed.
    ISBN: 9781118382844
    DDC: 575.4/52
    Language: English
    Note: Intro -- Phloem -- Contents -- Contributors -- Section A Introduction -- 1 Phloem, the Integrative Avenue -- 2 Cell Biology of Sieve Element-Companion Cell Complexes -- Development of the Sieve Element-Companion Cell Complex -- Symplastic Connections to and within the Phloem -- Origins and Development of Plasmodesmata -- Connections between SE-CCs and Surrounding Cells -- Sieve Pores-Connecting Sieve Elements into Sieve Tubes -- Modified Plasmodesmata between Sieve Elements and Companion Cells: The Pore-Plasmodesma Units -- Other Specialized Features of Sieve Elements -- The Sieve Element Reticulum -- Cytoskeletal Proteins in Mature Sieve Elements -- Transport between Sieve Element and Companion Cell -- Cytosolic Transport through PPUs -- Membrane-Associated Transport through PPUs -- Future Directions -- References -- 3 Fundamentals of Phloem Transport Physiology -- What's In?-Constituents and Their Concentrations in Sieve-Tube Sap -- Propulsion of a Nutrient Enriched Sap through Sieve Tubes-Pressure Flow and Its Physiological Implications -- Phloem Loading in Collection Phloem -- Phloem Loading Mechanisms and Pathways -- Pre-SE-CC Loading Transport Processes Are Common to All Phloem Loading Mechanisms and Pathways -- Apoplasmic Loaders-Probable Cellular Site of Apoplasmic Exchange and Membrane Transport Mechanisms -- Phloem Loading of Nutrients Other Than Sugars -- Phloem Loading of Water and SE-CC Water Relations -- Transport Phloem-the Multitasker -- Transport Phloem Functions -- Sugar and Amino N Leak and Retrieval Functions -- Net Resource Efflux from Transport Phloem -- Net Resource Influx into Transport Phloem -- Xylem-to-Phloem Exchange -- Release Phloem-Letting Go of the Translocation Stream -- Mapping Cellular Pathways of Phloem Unloading -- Some General Physiological Principles of Phloem Unloading. , Pressure Flow-Integrating Collection, Transport, and Release Phloem Functions -- Future Directions -- Acknowledgments -- References -- Section B Functional Aspects of Structural SE Components -- 4 Roles of Plasma Membrane Transporters in Phloem Functions -- Membrane Transporters and Loading of Resources in Collection Phloem -- Membrane Transporters Regulate Cytosolic Pool Sizes of Sugars in Mesophyll Cells Destined for Phloem Loading -- Sugars Are Retrieved into Mesophyll Cells during Their Symplasmic Transit to Collection Phloem -- Sugar Release in Apoplasmic Phloem Loading Species -- H+-ATPases: Membrane Potential Difference, ΔpH, and Alkalinization of Phloem Sap -- Membrane Transporters Loading Sucrose, the Ubiquitous Phloem Sugar, into SE-CCs -- Polyol and Inositol Transporters and Their Role(s) in Phloem Loading -- Potassium Channels: Working in Harmony with Sugar Transporters to Drive Phloem Translocation -- Phloem Loading of Water and Aquaporins -- Nitrogen (and in Some Circumstances Sulfur) Are Primarily Accumulated into the Phloem by Amino Acid Transporters -- Phloem Loading of Macroelements Other Than Potassium -- Microelement Phloem Loading: An Emerging Key Field in Biofortification -- Transport Phloem: A Plurality of Membrane Transport Functions -- Transporters Detected in the Transport Phloem -- Membrane Transporters Act in Retrieval -- Net Resource Efflux from Transport Phloem -- Net Resource Influx into Transport Phloem -- Xylem-to-Phloem Exchange of Solutes -- Letting Go: Membrane Transporters Participate in Phloem Unloading of Resources -- Membrane Transporters Contributing to Phloem Unloading in Growth Sinks -- Phloem Unloading in Storage Sinks: Fleshy Fruits and Tubers -- Resource Unloading in Developing Seeds: A Cacophony of Membrane Transporters in a Sink System Committed to an Apoplasmic Step in the Postphloem Unloading Pathway. , Aquaporins and Phloem Unloading of Water in Growth and Storage Sinks -- The Dark Side: Ferrymen Transporting Toxic Elements or Compounds -- Phloem Transporters Confer Adaptive Responses to Salt Stress -- Transporter Infidelity Opens Gates to Heavy Metals -- Phloem Transporters Engaged in Signal Transmission -- Phloem Loading/Unloading of Plant Hormones -- Sieve Tube Ion Channels Involved in Electrical Signaling -- Phloem Loading of Plant Defense Compounds -- Future Directions -- Acknowledgments -- References -- 5 Regulation of Sucrose Carrier Activities -- Functional Characteristics of Sucrose Transporters -- Cellular and Subcellular Localization of Sucrose Transporters Involved in Sucrose Uptake by Sieve Tubes -- Subcellular Localization of Sucrose Transporters -- A Model for the Endocytosis of Sucrose Transporters -- Vacuolar Sucrose Transporters -- Regulation of Sucrose Transporters -- Transcriptional Control of Sucrose Transporter Expression -- Posttranscriptional Regulation of Sucrose Transporters -- Posttranslational Control of Sucrose Transporters Expression -- Sucrose Sensing and Signaling -- Sucrose Transport and Gibberellins -- Sucrose Transport and Ethylene -- The Role of Sucrose Transporters Outside the Phloem: Sucrose Transport and Pollen Development -- Future Directions -- References -- 6 Cellular Basis of Electrical Potential Waves along the Phloem and Impact of Coincident Ca2+ Fluxes -- Electrical Long-Distance Signals in Higher Plants -- Action Potentials in Plants -- Variation Potentials in Higher Plants -- Stimulus-Specific Generation of APs and VPs? -- EPWs Trigger Ca2+ Influx via Diverse Ca2+ Permeable Channels into Sieve Elements -- Ca2+ Activities in Sieve Elements before, during, and after EPW Passage -- Ca2+-Permeable Channels of the Sieve Element Plasma Membrane. , Passage of EPWs, Ca2+ Influx, and Sieve Element Occlusion Mechanisms -- Ca2+ Hotspots as Result of a Limited Diffusion Range of Ca2+ Ions Released by Clustered Ca2+ Permeable Channels in SEs -- Ca2+ Channels and the Presence of Cytoskeleton in Sieve Elements? -- Electropotential Waves, Sieve-Element Cell Biology and Whole-Plant Responses -- Differential Effects of APs and VPs in Intact Plants -- Impact of Ca2+ Channels on Reversible Sieve-Element Occlusion in Intact Plants -- Collective Effects of Ca2+ Fluxes Generated by Sieve-Element Ca2+ Channels on Whole-Plant Function -- Future Directions -- References -- 7 Sieve Element Occlusion -- Callose -- Callose Biosynthesis -- Callose Deposition in Sieve Tubes -- P-Proteins -- Dispersive P-Protein Bodies -- Nondispersive P-Proteins -- Forisomes -- Sieve Plate Pore Occlusion: A Concerted Effort? -- Future Directions -- References -- Section C Long-Distance Signaling -- 8 Sieve Elements: Puzzling Activities Deciphered through Proteomics Studies -- Methods Used to Collect Sieve-Tube Sap -- Overview of Sieve-Tube Sap Composition -- Sieve-Tube Sap Proteome: An Integral Component of the Plant Communication System -- Noncell-Autonomous Proteins and Large Protein Complexes in Sieve Elements -- The Ubiquitin-Proteasome System: A Role in Protein Degradation or Signaling? -- Phytohormones and Signaling -- Calcium, Kinases, and Signal Transduction Pathways -- Metabolic Activities Reveal Oxygen Status of Phloem Tissues -- Low Oxygen Tensions and Adaptation to Primary Metabolism -- Production of Metabolites Acting on Defense and Detoxification -- Oxidative Metabolism, Antioxidant Defense, and Control of Redox State -- The Phloem Plays a Key Role in Plant Defense -- Defense Proteins and Response to Biotic and Abiotic Stresses -- Lectins and Storage Proteins -- Protease Inhibitors and Protein Turnover. , Structural Components of Sieve Elements -- SE Structural Proteins -- Sites of Sieve-Tube Sap Protein Synthesis -- Presence of the Translational Machinery in Sieve Tubes: An Enigmatic Puzzle -- Future Directions -- Acknowledgments -- References -- 9 Endogenous RNA Constituents of the Phloem and Their Possible Roles in Long-Distance Signaling -- Methods for Identifying Phloem RNAs -- Methods to Localize Specific RNAs in Tissue Sections -- Methods to Analyze RNAs in Sieve-Tube Sap Samples -- RNAs Identified in Sieve-Tube Sap -- mRNAs in Sieve-Tube Sap -- siRNAs in Sieve-Tube Sap -- miRNAs in Sieve-Tube Sap -- tRNAs and Other RNAs in Sieve-Tube Sap -- Methods for Studying RNA Transport in Sieve Tubes -- Demonstrating RNA Transport by Grafting Experiments -- Demonstrating RNA Phloem Transport by Particle Bombardment, Microinjection, or Transient Expression of Molecules -- Demonstrating RNA Transport in Natural "Grafts" Formed by Parasitic Plants -- Evidence for RNA Movement and Possible Functions of Phloem-Mobile RNAs -- Phloem-Mobile mRNAs -- Phloem-Mobile siRNAs -- Phloem-Mobile miRNAs -- Phloem-Mobile tRNAs and Other RNAs -- Import and Transport Mechanism of Phloem-Mobile RNAs -- Future Directions -- Acknowledgments -- References -- 10 The Effect of Long-Distance Signaling on Development -- The Protein of FLOWERING LOCUS T Functions as the Mobile Floral Signal -- Full-Length mRNA as a Long-Distance Signal -- Mobile GAI RNA -- The Long-Distance Transport of a BEL1-like mRNA Regulates Tuber Development -- Evidence for Movement of BEL5 RNA through the Phloem -- The Role of Untranslated Regions in RNA Transport -- Untranslated Regions of StBEL5 Mediate Transcript Mobility -- Future Directions -- Acknowledgments -- References -- 11 Plant Defense and Long-Distance Signaling in the Phloem -- Responses to Long-Distance (Systemic) Signaling. , Systemic Wound Response.
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  • 8
    Online Resource
    Online Resource
    Hauppauge :Nova Science Publishers, Incorporated,
    Keywords: Androgens. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (252 pages)
    Edition: 1st ed.
    ISBN: 9781620811887
    Series Statement: Endocrinology Research and Clinical Developments
    Language: English
    Note: Intro -- ANDROGENS -- ANDROGENS -- Contents -- Preface -- Androgen Deprivation Therapy for Advanced Prostate Cancer on the Ground of Androgen Milieu in the Prostate -- Abstract -- Abbreviations -- Introduction -- Androgen Milieu in Blood -- Androgen Milieu in the Prostate -- Prostate Cancer Aggressiveness and the Androgen Milieu in the Prostate and in Blood -- Intraprostatic Androgen Milieu during Androgen Deprivation Therapy -- Androgen Milieu in the Castration-Resistant Prostate Cancer -- Clinical-Translational Advances of Prostate Cancer -- Gonadotrophin-Releasing Hormone (GnRH) Antagonists: Degarelix -- Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 (CYP17A1) Inhibitors -- Abiraterone Acetate (Zytiga, Johnson & -- Johnson) -- Orteronel (TAK-700) [(1S)-1-(6,7-Dimethoxy-2-Naphthyl)-1-(1H-Imidazol-4-Yl)-2-Methylpropan-1-Ol] -- TOK-001 (VN/124-1) [3 -Hydroxy-17-(1H-Benzimidazole-1-Yl)Androsta-5,16-Diene] -- 3.-Hydroxysteroid Dehydrogenase Inhibitors -- Apoptone (HE3235) (17 -Ethynyl-5 -Androstan-3 , 17 -Diol) -- Inhibitors Targeting Androgen Receptor -- A New Androgen Receptor Antagonist, MDV3100 -- A New Androgen Receptor Antagonist, ARN-509 -- An Inhibitor of the Amino Terminal Domain (NTD) of the AR: EPI-001 -- The Prospects of the Androgen Deprivation Therapy on the Ground of Androgen Milieu in the Prostate -- Conclusion -- References -- Clinical Model of Androgen Deficiency - Clinical Model of Androgen Deficiency - Clinical Model of Androgen Deficiency - Androgen Deprivation Therapy and Its Effect on Bone Metabolism, Metabolism and Cognitive Functions -- Introduction -- Methods -- Androgen Deprivation Therapy (ADT) -- Testosterone: A Basal Overview of Biosynthesis, Metabolism and Its Action -- Androgens and Bone Metabolism -- ADT and Its Side Effects -- Bone Loss and Osteoporosis -- Osteoporosis. , Diagnosis of Osteoporosis -- ADT, PCa and Clinical Aspects of Bone Disease -- Treatment of ADT Induced Osteoporosis -- Androgens and Cognitive Functions -- Potential Mechanisms of Action -- Cognitive Functions and ADT -- Androgen Deprivation Therapy and Changes in Body Composition -- ADT and Insulin Resistance -- Early Metabolic Changes -- Late Metabolic Changes -- ADT and Lipid Alterations -- ADT, Metabolic Syndrome and Cardiovascular Disease -- References -- The Role of Testosterone in Male Erectile Dysfunction -- 1. Erectile Dysfunction -- 2. Definitions -- 2.1. Total Testosterone -- 2.2. Free Testosterone -- 2.3. Bio-Available/Bioactive Testosterone -- 3. Hypogonadism -- 3.1. Late Onset Hypogonadism -- 3.2. Hypogonadism Prevalence -- 4. Relationship between Testosterone and ED -- 5. Physiology of Erection -- 6. Influence of Testosterone on Penile Erection -- 6.1. NOS/cGMP Pathway -- 6.2. Source of NO -- 6.3. Phosphodiesterases (PDE) -- 7. Making the Diagnosis of Hypogonadism and Working up Erectile Dysfunction -- Patient History -- Physical Exam -- Laboratory Studies -- Specific Diagnostic Tests -- 7.1. Questionnaires -- 7.2. Laboratory Diagnosis -- 7.3. Total Testosterone -- What is the Lower Level of Testosterone Required to Maintain Erection? -- 7.4. Free Testosterone -- 7.5. Calculated Free Testosterone -- 7.6. Other Endocrine Markers -- 8. Testosterone and Testosterone Replacement Therapy (TRT) -- 8.1. Safety, Tolerability and Specific Considerations -- 8.2. Testosterone and PDE5 Inhibitors (PDE5-I) in ED -- References -- Roles of Androgen Receptor in Normal Prostate Development and Prostate Cancer Progression -- 1. Introduction -- 2. Dual Roles of the AR in Normal Prostate Development -- 2.1. Stromal AR: Proliferation Stimulator and Survival Factor -- 2.2. Epithelial AR: Survival Factor for Epithelial Luminal Cells. , 2.3. Epithelial AR: Suppressor for Epithelial Basal Intermediate Cell Proliferation -- 2.4. Epithelial AR: Survival Factor for Stromal Smooth Muscle Cell Differentiation -- 3. AR Dual Roles in Prostate Cancer Progression and Metastasis -- 3.1. Stromal AR: Stimulator for Tumor Progression and Metastasis -- 3.2. Epithelial AR: Survival Factor for Tumor Progression and Metastasis in Luminal Cells -- 3.3. Epithelial AR: Suppressor for Tumor Progression and Metastasis in Basal Intermediate Cells -- 3.4. Epithelial AR: Suppressor of Prostate Cancer Metastasis -- 4. AR Dual Roles in Human Prostate Cancer Cell Lines -- 4.1. AR in PC3 Cells: Suppressor for Proliferation and Metastasis -- 4.2. AR in LNCaP Cells: Proliferation Stimulator and Suppressor -- 4.3. AR in CWR22Rv1 Cells: Proliferation Stimulator and Suppressor -- 4.4. AR in PC346C Prostate Cancer Cells: Proliferation Stimulator and Suppressor -- 5. AR Dual Roles in Prostate Cancer Stem Cell Progression -- 6. AR Dual Roles and Human Prostate Cancer Clinical Data -- 7. The Impact of AR Dual Roles on Current Clinical ADT -- 7.1. Challenge to Current ADT -- 7.2. Target the AR at an Early Stage -- 7.3. Concomitant Treatment of AR Antagonism with Anti-Metastasis Agents -- Future Direction -- Conclusion -- References -- Endogenous Pathways for Steroidogenesis and Androgen Signalling in Prostate Cancer Cells -- Summary -- Introduction -- The Prostate -- Androgen Receptor -- Prostate Cancer and Treatment -- Links between Androgen Levels and Prostate Cancer Risk -- Steroidogenesis and Prostate Cancer -- Conclusion -- References -- The Role and Effects of Novel Androgen Therapy in the Treatment of Prostate Cancer -- Abstract -- I. Introduction -- II. Emergence of Castration Resistance: Androgen Regulation and Signaling -- III. Clinical Studies. , IV. Adverse Effects of Targeting Androgen Regulation: Recent Findings -- Conclusion -- References -- Androgens and Male Fertility: Spermatogenesis and Contraception -- Abstract -- Introduction -- Androgens -- Role of Androgens in Male Sexual Development -- Spermatogenesis -- Hypthalamic-Pituitary-Gonadal Axis -- Role of the Androgen Receptor -- Classical Testosterone Signaling Pathways -- Non-Classical Testosterone Pathways in Sertoli Cells -- Male Hormone Contraception -- References -- Androgens, Cognition and Social Behavior in Children* -- Introduction -- Androgens -- Testosterone -- Androstenedione -- Dehydroepiandrosterone (DHEA) -- Androgen-Secreting Glands -- Suprarenal Glands -- Gonads -- Testicles -- Ovaries -- Biosynthesis of Steroid Hormones -- Action Mechanisms of Androgens -- Sexual Differentiation of the Brain and Behavior -- Sexual Differentiation -- Genetic Sex -- Gonadal Sex -- Hormonal Sex -- Effects of Organization and Activation -- Relation of Androgens to Psychological Processes -- Relationship between Androgens and Social Behavior -- Conclusion -- References -- Androgens, Androgen Suppression, and Prostate Cancer: Recent Preclinical and Clinical Findings and Implications* -- Abstract -- Introduction -- Prevention Studies -- 5-Alpha Reductase Inhibitors -- Treatment Studies -- Role of ADT in Early Prostate Cancer -- ADT Combined with Radiation -- ADT Combined with Surgery -- ADT for Patients Ineligible for Local Definitive Therapy -- Role of Continuous ADT in Biochemical Recurrence of Prostate Cancer -- Early versus Late Therapy -- Peripheral Androgen Blockade -- Role of Continuous ADT in Advanced Disease -- Combined Androgen Blockade -- Antiandrogen Monotherapy -- Antiandrogen Withdrawal -- Intermittent ADT -- Role of Intermittent ADT in Biochemically Recurrent Prostate Cancer. , Role of Intermittent ADT in Locally Advanced or Metastatic Prostate Cancer -- Individual Dosing Based on Testosterone Levels -- Rapid Hormonal Testosterone Cycling -- Other Agents -- Ketoconazole -- Aminoglutethimide -- Abiraterone Acetate -- ADT Combined with Other Modalities -- ADT and Chemotherapy -- ADT and Vaccines -- Adverse Effects of ADT -- Skeletal Changes and Loss of Bone Mineral Density -- Hot Flashes -- Metabolic Syndrome -- Sexual Dysfunction -- Emotional and Cognitive Side Effects -- Systemic Effects -- Biology of Castrate-Resistant Prostate Cancer -- Potentially Therapeutic Approaches Targeting AR -- Conclusion -- References -- Index.
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  • 9
    Online Resource
    Online Resource
    Dordrecht :Springer Netherlands,
    Keywords: Climatic changes. ; Electronic books.
    Description / Table of Contents: This book examines the links between current environmental issues and food and nutrition security. It provides a unique collection of nutrition statistics, climate change projections, biofuel scenarios and food security information.
    Type of Medium: Online Resource
    Pages: 1 online resource (130 pages)
    Edition: 1st ed.
    ISBN: 9789400701106
    DDC: 363.8
    Language: English
    Note: Intro -- The Impact of Climate Change and Bioenergy on Nutrition -- Contents -- List of Boxes -- List of Figures -- Table -- Authors -- Chapter 1: Summary -- Background: Unacceptably Slow Progress in Reducing Hunger and Malnutrition -- Causations and Linkages: Conceptual and Analytical Frameworks -- Future Challenges, Major Issues and Risks -- Demographic Forces and Urbanization -- Structural Shifts in Food and Agriculture Systems -- Transboundary Movement of Disease -- Environmental and Energy Pressures -- Climate Change and Food and Nutrition Security -- Impacts on Agricultural Production -- Impacts on Food and Nutrition Security -- Social Impacts of Climate Change -- Adaptation and Mitigation Strategies for Climate Change -- Nutrition and Bioenergy -- Policies and Programmes for Improving Nutrition -- Governance Issues -- A Revitalised Twin-Track Approach -- Direct Nutrition Interventions -- Educating Girls -- Responding to Threats to Nutrition from Climate Change and Biofuel Demand -- Chapter 2: Introduction -- Purpose -- Concept and Content -- Chapter 3: World Food Insecurity and Malnutrition: Scope, Trends, Causes and Consequences -- Dimensions of the Nutrition Problem -- Hidden Hunger -- Box 3.1 Key Definitions and Use of Terminology -- The Deadly Scourge of Child Malnutrition -- Box 3 .2 Twenty-Four Countries are Home to 80% of the World's Stunted Preschoolers -- Nutrition Throughout the Lifecycle -- HIV/AIDS and Nutrition -- Water, Sanitation and Nutrition -- The Double Burden of Malnutrition -- Hunger Crises -- Unacceptably Slow Progress in Reducing Hunger and Malnutrition -- Causations and Linkages: Conceptual and Analytical Frameworks -- Costs of Malnutrition -- Future Challenges, Major Issues and Risks -- Demographic Forces and Rapid Urbanization -- Structural Changes in the Food and Agricultural System. , Transboundary Pests and Diseases -- Environmental and Energy Concerns -- Chapter 4: Climate Change and Food and Nutrition Security -- Overview of Climate Change - Evidence and Effects -- Evidence -- Effects -- Impacts of Climate Change on the Human and Global Environment -- Vulnerable Regions -- Vulnerable Ecosystems -- Vulnerable Populations -- Impacts on the Four Food Security Dimensions: Availability, Stability, Access and Utilization -- Climate Change Impacts on Food Availability -- Climate Change Impacts on Food Stability and Access -- Climate Change Impacts on Food Utilization -- Care and Feeding -- Food Safety -- Access to Clean Water -- Health and Sanitation -- Box 4.1 The Interaction Between Nutrition and Infection -- Links Between Global Climate Change, Food Security, Hunger and Nutrition -- Social Impacts of Climate Change -- Box 4.2 Climate Change and Conflict in Sudan -- Adaptation and Mitigation Strategies -- Adaptation Strategies -- Mitigation Strategies -- Chapter 5: Nutrition and Bioenergy -- Overview -- Why Biofuel? Why Now? -- Government Support and Subsidies -- Prevalence of Biofuel Production -- State of Technology -- Environmental Implications -- Nutrition Impacts -- Diversion of Food and Feed to Fuel and Rising Food Prices -- Mitigation of Negative Impacts of Biofuels -- Development of International Standards and a Regulatory Regime -- Sustainable and Pro-poor Production of Biofuels -- FAO Activities -- Chapter 6: Policies and Programmes for Improving Nutrition -- International Initiatives -- Policies and Programmes -- Governance Issues -- A Revitalised Twin-Track Approach -- Box 6.1 Cutting Hunger in Brazil -- Improving and Increasing Investments in Agriculture -- Income and Employment Generation for Nutritional Improvement -- Safety Net Programmes -- Insurance to Preserve Assets Against Shocks. , Direct Nutrition Interventions -- Education for All -- Priorities and Approaches for Responding to Threats to Nutrition from Climate Change and Biofuel Demand -- Need for Serious Global Governance with Regard to Climate Change -- Policies for Responding to Rising Bioenergy Demand -- Chapter 7: Conclusions and Recommendations -- Responding to Climate Change -- Assuring Pro-poor and Sustainable Biofuel Development -- Making Nutrition a Development Priority -- Appendices -- Appendix 1: Scenarios of the IPCC's Special Report on Emissions Scenarios (SRES) 1 -- Appendix 2: IFPRI IMPACT Model 2 -- References -- Index.
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  • 10
    Online Resource
    Online Resource
    New York, NY :Springer,
    Keywords: Solar activity. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (404 pages)
    Edition: 1st ed.
    ISBN: 9781461436737
    Language: English
    Note: Intro -- Contents -- Preface -- The Solar Dynamics Observatory (SDO) -- Abstract -- Preface: Living with a Star and the Solar Dynamics Observatory -- Introduction -- History -- The Spacecraft Summary -- Science Goals -- Science Investigation Teams -- Atmospheric Imaging Assembly -- Extreme Ultraviolet Variability Experiment -- Helioseismic and Magnetic Imager -- Science Data Capture Requirement -- Ground System and Mission Operations -- SDO Orbit and Mission Phases -- SDO Data -- Rules of the Road for Data Use -- Browse and Public Access Data -- Final Data Archive -- Summary -- Acknowledgements -- References -- The Atmospheric Imaging Assembly (AIA) on the Solar Dynamics Observatory (SDO) -- Abstract -- Introduction -- Science Overview -- Energy Input, Storage, and Release: The Dynamic Coronal Structure -- Coronal Heating and Irradiance: Thermal Structure and Emission -- Transients: Sources of Radiation and Energetic Particles -- Connections to Geospace: Material and Magnetic-Field Output of the Sun -- Coronal Seismology: A Diagnostic to Study Coronal Waves and Oscillations -- Instrument Overview -- Mirrors and Multilayer Coatings -- Filters -- CCD Detector and Camera System -- Guide Telescope and Image-Stabilization System -- Mechanisms -- Electronics and Software -- Instrument Calibration -- Instrument Operations -- Data Processing -- Level 1 Data Processing -- Level 1.5 Data Processing -- Data Distribution -- Conclusion -- Acknowledgements -- References -- Initial Calibration of the Atmospheric Imaging Assembly (AIA) on the Solar Dynamics Observatory (SDO) -- Abstract -- Introduction -- Photometric Calibration -- Measuring the Response Function -- Geometric Area -- EUV Filters -- Mirrors -- CCDs -- UV Optics -- Contamination -- Wavelength Response -- Channel Crosstalk -- Error Budget -- Cross-Calibration with EVE -- Temperature Response. , Instrument Characterization -- Camera-CCD System Characterization -- Flat-Field -- Optical Performance -- Filter Mesh Diffraction -- Stray Light -- Guide Telescope-ISS -- Image Coalignment -- Compression -- Conclusion -- Acknowledgements -- Appendix: Accessing the Response Functions -- References -- Heliophysics Event Knowledgebase for the Solar Dynamics Observatory (SDO) and Beyond -- Abstract -- Introduction -- HEK Design Goals -- Heliophysical Events -- Example Usage -- HEK Implementation -- Mission (Coverage) Assets -- Capturing Planning Metadata -- JSOC Assets -- Event Detection System -- AIA Visualization Center -- Browse Products -- Public Assets -- The Heliophysics Event and Coverage Registries -- HEK Services -- HEK Clients -- Data Request Management -- Conclusions -- Acknowledgements -- References -- Computer Vision for the Solar Dynamics Observatory (SDO) -- Abstract -- Introduction -- Operations Concept and Overview of Modules -- Flare Detection -- H Filaments -- Sigmoids -- CME Recognition and Tracking -- Coronal Dimming Regions -- Jets -- Oscillations -- EIT Wave Tracking -- Detection and Analysis of Active Regions and Coronal Holes -- X-ray Bright Points -- Correlation with Other Databases -- Correlation with Jets -- Magnetic Feature Tracking and Sunspots -- Polarity Inversion Line Mapping -- Nonlinear Force-free Field Extrapolations -- Trainable Feature Recognition and Retrieval -- Method -- Discovery of New Features -- A Pipeline for the Generation of Feature and Event Metadata -- Computing Facilities at LMSAL -- SAO Computing Facilities -- Interfacing to DRMS -- Module Testing -- Community Access to Metadata at SAO -- Conclusions -- Acknowledgements -- References. , Extreme Ultraviolet Variability Experiment (EVE) on the Solar Dynamics Observatory (SDO): Overview of Science Objectives, Instrument Design, Data Products, and Model Developments -- Abstract -- Introduction -- EVE Science Plan -- EVE Science Objectives -- EVE Objective 1 - Specify Solar EUV Irradiance -- EVE Objective 2 - Understand Why Solar EUV Irradiance Varies -- EVE Objective 3 - Forecast Solar EUV Variations -- EVE Objective 4 - Understand Response of Geospace Environment -- EVE Science Team -- EVE Measurement Requirements -- EVE Instrumentation -- MEGS-A Instrument -- MEGS-B Instrument -- MEGS-SAM Instrument -- MEGS-P Instrument -- ESP Instrument -- Other EVE Subsystems -- EVE Data Products -- EVE Level 0C - Space Weather Product -- EVE Level 1 -- EVE Level 2 -- EVE Level 3 -- EVE Data System -- Solar Irradiance Models -- NRLEUV Model -- FISM Model -- SIP Hybrid System of Data and Models -- Earth's Atmospheric Models -- TDIM, IFM, and GAIM Models -- CTIPe Model -- NRLMSIS Model -- JB2006 and JB2008 Models -- Summary -- Acknowledgements -- References -- Extreme Ultraviolet Variability Experiment (EVE) Multiple EUV Grating Spectrographs (MEGS): Radiometric Calibrations and Results -- Abstract -- Introduction -- EVE Instruments -- EVE MEGS Calibration Heritage -- SURF Calibration Setup -- MEGS A and B Calibration -- MEGS A and B Algorithms -- Wavelength Scale, Bandpass, and Spectral Resolution -- LASP Calibration Setup -- Wavelength Scale -- Bandpass -- Spectral Resolution -- Corrected Count Rate -- Dark Count Correction -- Scattered Light -- Linearity -- Gain Correction -- Invalid Pixel Masking -- SURF Responsivity -- SURF Beam Current -- SURF Flux -- Field-of-View (FOV) Maps -- Higher-Order Correction -- Flight Responsivity -- MEGS P Calibration -- MEGS P Algorithm -- Uncertainty Algorithm -- Calibration Results. , Application for MEGS In-flight Calibrations -- MEGS SAM Calibration -- Responsivity Algorithm -- Uncertainty Algorithm -- Calibration Results -- Solar EUV Measurements on 14 April 2008 -- MEGS A and B -- MEGS P -- SAM -- Conclusions -- Acknowledgements -- References -- EUV SpectroPhotometer (ESP) in Extreme Ultraviolet Variability Experiment (EVE): Algorithms and Calibrations -- Abstract -- Introduction -- ESP Scientific Objectives -- ESP Overview -- An Algorithm to Convert ESP Count Rates into Solar Irradiance -- Results from the Ground Tests -- Thermal Changes of Dark Count Rates -- Thermal Changes of Reference Count Rates -- ESP Pre-flight Calibration -- ESP Variables: Where They Are Measured and How Accurately -- ESP Calibration Overview -- Results from the BL-9 Calibration -- ESP Filter Transmissions -- Measured Transmission of the Diffraction Grating -- On-axis Efficiencies -- Results from the BL-2 Radiometric Pre-flight Calibration -- ESP Responses for the Tilted Positions -- BL-2 Calibration for ESP FOV Maps -- BL-2 Calibration for ESP On-axis Position -- ESP Sensitivity to the Higher Orders (BL-2 Order Sorting Test) -- A Comparison of ESP Measured Irradiance from the Sounding Rocket Flight with other Measurements -- Concluding Remarks -- Acknowledgements -- References -- The Helioseismic and Magnetic Imager (HMI) Investigation for the Solar Dynamics Observatory (SDO) -- Abstract -- Overview -- Top Level Goals -- Scope -- The Helioseismic and Magnetic Imager Instrument -- HMI Data Products -- Team, Collaborations and Community -- History -- HMI Science Goals -- Science Overview -- Scientific Goals -- Convection-Zone Dynamics and the Solar Dynamo -- Structure and Dynamics of the Tachocline -- Variations in Differential Rotation -- Evolution of Meridional Circulation -- Dynamics in the Near-Surface Shear Layer. , Origin and Evolution of Sunspots, Active Regions, and Complexes of Activity -- Formation and Deep Structure of Magnetic Complexes of Activity -- Active Region Source and Evolution -- Magnetic Flux Concentration in Sunspots -- Sources and Mechanisms of Solar Irradiance Variation -- Sources and Drivers of Solar Activity and Disturbances -- Origin and Dynamics of Magnetic Sheared structures and alpha-type Sunspots -- Magnetic Configuration and Mechanisms of Solar Flares -- Emergence of Magnetic Flux and Solar Transient Events -- Evolution of Small-Scale Structures and Magnetic Carpet -- Links Between the Internal Processes and Dynamics of the Corona and Heliosphere -- Complexity and Energetics of the Solar Corona -- Large-Scale Coronal Field Estimates -- Coronal Magnetic Structure and Solar Wind -- Precursors of Solar Disturbances for Space-Weather Forecasts -- Far-Side Imaging and Activity Index -- Predicting Emergence of Active Regions by Helioseismic Imaging -- Determination of Magnetic Cloud Bs Events -- Theoretical Support and Modeling -- Data Products -- Global Helioseismology -- Local-Area Helioseismology -- Full-Disk Velocity and Sound-Speed Maps -- Synoptic Maps of Mass Flows and Sound-Speed Perturbations -- Synoptic Maps of Horizontal Flows in Upper Convection Zone -- Higher-Resolution Maps Zoomed on Particular Active Regions -- Deep-Focus Maps -- Far-Side Images of the Sound-Speed Perturbations -- Magnetography -- Vector Magnetic Field -- Continuum Intensity -- Real-Time Products -- Summary -- Acknowledgements -- References -- Design and Ground Calibration of the Helioseismic and Magnetic Imager (HMI) Instrument on the Solar Dynamics Observatory (SDO) -- Abstract -- Introduction -- Instrument Description -- HMI Optics Package -- Imaging Optics -- Polarization Selectors -- Filters -- Front Window -- Blocking Filter -- Lyot Filter. , Michelson Interferometers.
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