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  • S. Karger AG  (2)
  • 2005-2009  (2)
  • 2009  (2)
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  • S. Karger AG  (2)
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  • 2005-2009  (2)
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  • 2009  (2)
  • 1
    In: Kidney and Blood Pressure Research, S. Karger AG, Vol. 32, No. 2 ( 2009), p. 141-149
    Abstract: Obesity increases the risk for chronic kidney disease (CKD). By analyzing data on individuals who underwent general health screening in two consecutive years, we investigated whether changes in body mass index (BMI) or waist circumference (WC) were associated with the appearance or disappearance of the CKD components; micro-/macroalbuminuria (≥30 mg urinary albumin per gram creatinine) and a low estimated glomerular filtration rate (eGFR; 〈 60 ml/min/1.73 m 〈 sup 〉 2 〈 /sup 〉 ). Logistic regression analysis showed that in men with micro-/macroalbuminuria at the first visit, a BMI reduction of ≥0.42 or a WC reduction of ≥3.0 cm over the 1-year period resulted in a significantly reduced incident of micro-/macroalbuminuria at the second visit. On the other hand, a BMI gain of ≥0.33 over 1 year in men without micro-/macroalbuminuria and a low eGFR at the fist visit significantly increased the incident of micro-/macroalbuminuria and a low eGFR, respectively, at the second visit. These findings indicate that lowering the obesity indexes in men with micro-/macroalbuminuria reduced the incidence of this condition at the 1-year follow-up and that, on the contrary, an increase in BMI in men without micro-/macroalbuminuria and a low eGFR at the first examination increased the risk of these conditions during the 1-year follow-up period.
    Type of Medium: Online Resource
    ISSN: 1420-4096 , 1423-0143
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2009
    detail.hit.zdb_id: 1482922-8
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  • 2
    Online Resource
    Online Resource
    S. Karger AG ; 2009
    In:  Kidney and Blood Pressure Research Vol. 32, No. 6 ( 2009), p. 421-427
    In: Kidney and Blood Pressure Research, S. Karger AG, Vol. 32, No. 6 ( 2009), p. 421-427
    Abstract: 〈 i 〉 Aims and Methods: 〈 /i 〉 By analyzing data from 2,861 individuals who underwent general health screening 2 years running, we have investigated the impact of changes in waist circumference (WC) and body mass index (BMI) over a 1-year period on systolic blood pressure (BPs). We termed WC, BMI, and BPs at the first visit as WC1, BMI1, and BPs1, respectively, and those at the second visit as WC2, BMI2, and BPs2, respectively. The %dWC, %dBMI, and %dBPs was defined as (WC2 – WC1)/WC1 × 100, (BMI2 – BMI1)/BMI1 × 100, and (BPs2 – BPs1)/BPs1 × 100, respectively. 〈 i 〉 Results: 〈 /i 〉 In multivariate regression analysis using age, BPs1, WC1, and %dWC as independent variables, %dWC was a significant predictor for %BPs only in men. %dBMI was a significant predictor for %BPs in both genders when age, BPs1, BMI1, and %dBMI were used as independent variables. Compared with individuals with both %dWC 〈 0 and %dBMI 〈 0, age-adjusted %dBPs was significantly greater in those with both %dWC 〈 0 and %dBMI ≧0; however, it did not significantly differ in those with both %dWC ≧0 and %dBMI 〈 0. 〈 i 〉 Conclusion: 〈 /i 〉 Our data suggest that the impact of BMI change might be greater than WC change in terms of BPs change during this short period.
    Type of Medium: Online Resource
    ISSN: 1420-4096 , 1423-0143
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2009
    detail.hit.zdb_id: 1482922-8
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
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