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  • Ovid Technologies (Wolters Kluwer Health)  (2)
  • 1995-1999  (2)
  • 1996  (2)
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  • Ovid Technologies (Wolters Kluwer Health)  (2)
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  • 1995-1999  (2)
Year
  • 1996  (2)
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  • 1
    Online Resource
    Online Resource
    Childhood chronic inflammatory demyelinating neuropathies : Clinical course and long-term follow-up
    Ovid Technologies (Wolters Kluwer Health) ; 1996
    In:  Neurology Vol. 47, No. 1 ( 1996-07), p. 98-102
    Details
    In: Neurology, Ovid Technologies (Wolters Kluwer Health), Vol. 47, No. 1 ( 1996-07), p. 98-102
    Abstract: Chronic inflammatory demyelinating neuropathy (CIDP) is a rare disease in childhood.We reviewed the clinical characteristics, response to therapy, and long-term prognosis in 13 children (1.5 to 16 years of age) diagnosed with CIDP at Washington University Medical Center, St. Louis, and the Royal Children's Hospital, Melbourne, Australia, between 1979 and 1994. The most common presenting symptom (in 11/13 [85%]) was lower extremity weakness associated with difficulty in walking. Preceding events within 1 month of onset, mostly intercurrent infections or vaccinations, occurred in seven children (54%). The disease was monophasic in three children (23%). One relapse occurred in four (30%) and multiple relapses in six (46%). All patients had at least short-term response to steroids. Three children (23%) recovered completely during the first year. Ten children (77%) had residual weakness after an average follow-up of 6 years. There seems to be two populations of children with CIDP. One subgroup, with a favorable prognosis, progressed to peak disability over less than 3 months; these children often have a monophasic course with complete resolution of symptoms and signs and withdrawal from all medications by 1 year after onset. A second subgroup progressed for 3 months or longer; these children all required substantial doses of prednisone for prolonged periods and had considerable long-term morbidity with persistent weakness. NEUROLOGY 1996;47: 98-102
    Type of Medium: Online Resource
    ISSN: 0028-3878 , 1526-632X
    URL: Article
    DOI: 10.1212/WNL.47.1.98
    RVK:
    XA 10000
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 1996
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    Online Resource
  • 2
    Online Resource
    Online Resource
    Atrioventricular Node Reentry With ‘Smooth’ AV Node Function Curves : A Different Arrhythmia Substrate?
    Ovid Technologies (Wolters Kluwer Health) ; 1996
    In:  Circulation Vol. 93, No. 5 ( 1996-03), p. 969-972
    Details
    In: Circulation, Ovid Technologies (Wolters Kluwer Health), Vol. 93, No. 5 ( 1996-03), p. 969-972
    Abstract: Background Some patients with otherwise typical AV node reentry do not manifest discontinuous AV node function curves. We examined the effects of an ablation in the slow-pathway region in patients with smooth AV node function curves. Methods and Results Fifteen patients with AV node reentrant tachycardia (AVNRT) and discontinuous AV node function curves were compared with 15 patients with AVNRT and smooth AV node function curves. In the group with a discontinuous curve, the “net” anterograde effective refractory period (AERP) of the AV node increased (270±28 versus 304±37 ms, P =.03) and AERP of the remaining fast pathway decreased (367±100 versus 304±37 ms, P =.026) after the ablation. In the group with a smooth curve, the AERP of the AV node increased (266±42 versus 299±76 ms, P =.07) and the anterograde Wenckebach cycle length increased (336±66 versus 379±86 ms, P =.008) after the ablation. Retrograde conduction over the AV node was similar in both groups and was unchanged after ablation. The longest attainable AH interval (AH max ) measured during atrial extrastimulus testing was more prolonged in patients with a discontinuous curve than in patients with a smooth curve (326±48 versus 250±70 ms, P =.002). The AH max shortened in both groups after ablation (326±48 versus 173±34 ms, P 〈 .0001, and 250±70 versus 179±34 ms, P 〈 .0003, respectively) and were similar. Successful ablation in the slow-pathway zone in patients with a smooth AV node function curve resulted in the loss of the “tail” of the curve representing the slow pathway. Conclusions These data suggest that the smooth AV node function curve consists of two distinct components representing both fast and slow AV node pathways even when the typical discontinuity is absent.
    Type of Medium: Online Resource
    ISSN: 0009-7322 , 1524-4539
    URL: Article
    DOI: 10.1161/01.CIR.93.5.969
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 1996
    detail.hit.zdb_id: 1466401-X
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