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  • 1
    Electronic Resource
    Electronic Resource
    The Formation of Diselenide Bridges in Proteins by Incorporation of Selenocysteine Residues: Biosynthesis and Characterization of (Se)2-Thioredoxin (1994)
    s.l. : American Chemical Society
    Biochemistry 33 (1994), S. 3404-3412 
    Details
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/bi00177a034
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  • 2
    Electronic Resource
    Electronic Resource
    Ab initio study of the potential energy surfaces of doublet valence and Rydberg states of FCO (1994)
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 101 (1994), S. 3973-3980 
    Details
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: Multireference configuration interaction calculations (MRD-CI) were carried out in order to obtain the bending and stretching potential energy curves of several low-lying electronic states of the fluoroformyl radical FCO. The study of interactions between valence and Rydberg states as well as that of the dissociative behavior is included in the investigation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.467515
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  • 3
    Electronic Resource
    Electronic Resource
    Ab initio investigation of the vibrational structure of absorption and emission spectra of FCO (1994)
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 101 (1994), S. 3981-3988 
    Details
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: Results of an ab initio study of the vibrational structure of several electronic spectral systems of FCO are presented. An interpretation of hitherto recorded spectra, as well as a prediction of features of yet unobserved electronic transitions is given. The absorption spectra observed in the uv spectral region are ascribed to the transitions involving the first excited states of 2A' and 2A‘ character. The emission spectrum obtained by Toby and Toby [J. Phys. Chem. 85, 4071 (1981)] is assigned to the transition X 2A'←2 2A‘. Reassignment of some observed vibrational bands is proposed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.467516
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  • 4
    Electronic Resource
    Electronic Resource
    Avidin Can be Forced to Adopt Catalytic Activity (1994)
    s.l. : American Chemical Society
    Journal of the American Chemical Society 116 (1994), S. 9369-9370 
    Details
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ja00099a080
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  • 5
    Electronic Resource
    Electronic Resource
    Recognition of Dyes by K2SO4 Crystals: Choosing Organic Guests for Simple Salts (1994)
    s.l. : American Chemical Society
    Journal of the American Chemical Society 116 (1994), S. 5519-5520 
    Details
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ja00091a086
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  • 6
    Electronic Resource
    Electronic Resource
    Adhesin regulatory genes within large, unstable DNA regions of pathogenic Escherichia coli: cross-talk between different adhesin gene clusters (1994)
    Oxford, UK : Blackwell Publishing Ltd
    Molecular microbiology 11 (1994), S. 0 
    Details
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: The uropathogenic Escherichia coli strain 536 possesses two large, unstable DNA regions on its chromosome, which were termed pathogenicity islands (pais). Deletions of pais, which occur with relatively high frequency in vitro and in vivo, lead to avirulent mutants. The genetic determinants for production of haemolysin (Hly) and P-related fimbriae (Prf) are located in one of these islands. Deletion of this pathogenicity isiand (paill) not only removes the hly- and prf-specific genes, but also represses S fimbriae (Sfa), although the sfa genes of this virulence factor are not located on paill. We have identified two regulatory genes, prfB and prfl, of the prf gene cluster that are homologous to the sfa regulatory genes staB and SfaC, respectively. Mutations in sfaB and sfaC that inhibit transcription of the major fimbrial subunit gene sfaA were complemented by the homologous prf genes, suggesting communication between the two fimbrial gene clusters in the wild-type strain. Chromosomal mutagenesis of the two prf regulators in strain 536 repressed transcription of sfaA, detected by Northern hybridization and a chromosomal sfaA-lacZ fusion. In addition, haemagglutination assays measured a lower level of S fimbriae in these mutants. Expression of the cloned prf regulators in trans reversed the effect of the mutations; furthermore, constitutive expression of prfB or prfl could also overcome the repression of S fimbriae in a strain that had lost the pathogenicity islands. Virulence assays in mice established that the prf mutants were less virulent than the wild-type strain. The results demonstrate that cross-regulation of two unlinked virulence gene clusters together with the co-ordinate loss of large DNA regions significantly influences the virulence of an extraintestinal E. coli wild-type isolate.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2958.1994.tb00336.x
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  • 7
    Electronic Resource
    Electronic Resource
    Mineralstoffe und Aminosäuren in den Körnern der neu kultivierten „Pseudo-Getreide“-ArtAmaranthus hypochondriacus (1994)
    Springer
    European food research and technology 198 (1994), S. 284-286 
    Details
    ISSN: 1438-2385
    Source: Springer Online Journal Archives 1860-2000
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Description / Table of Contents: Zusammenfassung Die Mineralstoffe und die Aminosäu-rezusammensetzung der Samen von kultiviertemAmaranthus hypochondriacus wurden untersucht. Die Konzentrationen der Mineralstoffe inAmaranthus-Körnern sind ähnlich denen in Weizen oder auch der Erbse. Die Standorte der Pflanzen haben allerdings einen bedeutenden Einfluß. Der Gesamt-Aminosäuregehalt und besonders die Menge der essentiellen Aminosäuren (Lysin, Arginin usw.) sind höher als in den Samen von Weizen und Mais. Die kultiviertenAmaranthus-Arten haben deshalb nicht nur vorteilhafte ökologische (Dürrefestigkeit, Anspruchslosigkeit), sondern auch positive ernährungsphysiologische Eigenschaften.
    Notes: Abstract The mineral elements and the amino acids in seeds of cultivatedAmaranthus hypochondriacus were studied. The following conclusions can be made: 1. The contents of minerals inAmaranthus seed are similar to those of wheat and (except of a few elements: P, K) of pea. The habitats of plants, especially the soil conditions effect importantly on minerals.-2. The total amino acid content and mainly the rate of essential amino acids (lysine, arginine etc) are higher than those in seeds of wheat and maize and this fact create the importance of cultivation and utilisation of this plant. The cultivatedAmaranthus species have favourable ecological properties (drought resistence, wantlessness) too.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01193175
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  • 8
    Electronic Resource
    Electronic Resource
    Kalium-Gehalt von eßbaren Wildpilzen (1994)
    Springer
    European food research and technology 198 (1994), S. 33-35 
    Details
    ISSN: 1438-2385
    Source: Springer Online Journal Archives 1860-2000
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Description / Table of Contents: Zusammenfassung Der Kaliumgehalt von eßbaren höheren Pilzarten beträgt durchschnittlich 34,35 g/kg−1 Trockenmasse (Standardabweichung: 12,91), er ist somit bedeutend und stellt eine wertvolle K-Quelle für die menschliche Ernährung dar. Die Kalium-Konzentration der Pilze ist relativ konstant. Eine Akkumulation von Kalium wird in den Proben nicht gefunden. Diese Tatsache wird durch Ergebnisse anderer Autoren bestätigt.
    Notes: Abstract The average potassium content of edible higher mushroom species is 34,35 g/kg−1 dry matter (SD:12,91) and thus an important and valuable K-source for human diet. The K-concentration of mushrooms is relatively constant. An accumulation of potassium in the mushroom samples analysed was not found. This fact is confirmed by the results of other authors, too.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01195279
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  • 9
    Electronic Resource
    Electronic Resource
    Die Kupfer-, Mangan- und Zink-Gehalte einiger eßbarer Großpilzarten (1994)
    Springer
    European food research and technology 198 (1994), S. 469-472 
    Details
    ISSN: 1438-2385
    Source: Springer Online Journal Archives 1860-2000
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Description / Table of Contents: Zusammenfassung 56 Proben eßbarer, verbreiteter Großpilzarten wurden auf Kupfer-, Mangan- und Zink-Gehalte analysiert. Die durchschnittliche Kupferkonzentration der Pilzproben (56,16 mg/kg Trockenmasse) ist relativ hoch (im Vergleich zu grünen Pflanzen), einige Pilzgruppen (Agaricus- undMacrolepiota-Arten) zeigen Kupfer-Akkumulation (bis 226 mg/kg). Ausgesprochene Mangan-Akkumulation wurde beiLepista nebularis undPluteus atricapillus nachgewiesen. Der Zink-Gehalt der Pilzproben (duchschnittlich: 104,1 mg/kg, zwischen 7,71 mg/kg (Lepista nebularis) und 194,3 mg/kg (Agaricus silvaticus) ist relativ ausgeglichen, Akkumulationser- scheinungen wurden nicht festgestellt.
    Notes: Abstract Fifty six samples of edible, wide-spread species of higher fungi were analysed for copper-, manganese and zinc-contents. The average copper concentration of the samples is high (56,16 mg/kg dry mass) as compared to the green plants. Some groups of fungi (Agaricus andMacrolepiota species) are considerable copper-accumulators (until 226 mg/kg DM). Pronounced accumulation of manganese was reported in the case ofLepista nebularis andPluteus atricapillus. The zinc-content of fungi (average: 104,1 mg/kg DM, between 7,71 mg/kg (Lepista nebularis) and 194, 3 mg/kg (Agaricus silvaticus) is relatively balanced, accumulation were not established.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01192842
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  • 10
    Electronic Resource
    Electronic Resource
    Morning versus evening administration of nifedipine gastrointestinal therapeutic system in the management of essential hypertension (1994)
    Springer
    Journal of molecular medicine 72 (1994), S. 864-869 
    Details
    ISSN: 1432-1440
    Keywords: Nifedipine gastrointestinal therapeutic system ; Essential hypertension ; Ambulatory blood pressure measurement
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The nifedipine gastrointestinal therapeutic system (GITS) is a recently developed controlled-release formulation for once-a-day dosing. We evaluated the influence of morning versus evening administration of the drug in a randomized double-blind cross-over study including 15 essential hypertensives. Five patients had to be excluded from blood pressure analysis because of noncompliance (three cases) or intolerable side effects (two cases). To assess the exact duration of the antihypertensive efficacy noninvasive automatic ambulatory blood pressure monitoring was performed. After a placebo period patients were given 30 mg nifedipine GITS either at 1000 or 2200 hours. Twenty-four-hour systolic and diastolic blood pressure profiles documented a sustained antihypertensive effect of both nifedipine regimens throughout the whole period without affecting the circadian rhythm. Statistical analysis revealed no significant difference between morning and evening administration. Two patients stopped their medication because of intolerable side effects (fatigue and muscle cramps, respectively). Two more cases suffered from mild reversible headache which provoked no discontinuation of the drug. In conclusion our results document a sustained antihypertensive efficacy of 30 mg nifedipine GITS in patients with moderate essential hypertension. Time of administration has no impact on day- and nighttime blood pressure control.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00190742
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