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  • Blackwell Publishing Ltd  (5)
  • 1990-1994  (5)
  • 1992  (5)
Document type
Publisher
Years
  • 1990-1994  (5)
Year
  • 1
    Electronic Resource
    Electronic Resource
    Acute and Chronic Ethanol Exposure Alters the Function of Hippocampal Kainate Receptors Expressed in Xenopus Oocytes (1992)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 58 (1992), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract: The effects of acute and extended ethanol exposure on N-methyl-d-aspartate- and kainate-induced currents were examined electrophysiologically in Xenopus oocytes expressing rat hippocampal mRNA. Ethanol inhibited responses stimulated by low and high concentrations of N-methyl-d-aspartate to a similar degree. However, responses produced by low or high concentrations of kainate were differentially inhibited by ethanol. Low kainate concentration responses were much more sensitive to ethanol than high kainate concentrations (e.g., 50 mM ethanol inhibited 12.5 μM kainate responses by 45% compared to 15% inhibition of 400 μM kainate responses). In oocytes cultured in 100 mM ethanol for 1–5 days, the ethanol inhibition of maximum N-methyl-d-aspartate and kainate responses was not different from that in non–ethanol-exposed oocytes. Ethanol treatment, however, selectively decreased the ethanol sensitivity of low kainate concentration responses. Currents stimulated by N-methyl-d-aspartate or kainate were not different between control and ethanol-treated oocytes, indicating that ethanol exposure did not interfere with channel expression. The selective actions of acute and extended ethanol exposure on low kainate responses may indicate selective actions of ethanol on subtypes of kainate receptors expressed in oocytes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-4159.1992.tb11380.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Controlling Diffuse Pollution of Groundwater from Agriculture and Industry (1992)
    Oxford, UK : Blackwell Publishing Ltd
    Water and environment journal 6 (1992), S. 0 
    Details
    ISSN: 1747-6593
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Notes: The greatest threat of contamination to groundwater resources is posed by pollutants from diffuse sources, yet legislation in the UK has until recently been focused on point sources. The problem of widespread pollution from industrial sources is described and compared with that from agriculture. The legislative controls available under the Water Resources Act 1991 are outlined, and the approach adopted by the National Rivers Authority in its Groundwater Protection Policy is discussed with respect to the concept of groundwater vulnerability.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1747-6593.1992.tb00792.x
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Possible Substrates of Ethanol Reinforcement: GABA and Dopamine (1992)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 654 (1992), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1992.tb25956.x
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    The response times during anaesthesia of pulse oximeters measuring oxygen saturations during hypoxaemic events (1992)
    Oxford, UK : Blackwell Publishing Ltd
    Anaesthesia 47 (1992), S. 0 
    Details
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Episodes of desaturation were recorded simultaneously by computer from two Ohmeda Biox 3700 pulse oximeters, one with an ear and one with a finger probe, on patients undergoing anaesthesia. Over a period of 6 months, 28 episodes of desaturation were detected. Analysis of the recordings showed the mean minimum saturations recorded for ear and finger probes were 86.3% and 83.5% respectively (p 〈 0.01). The mean delay for finger compared to ear pulse oximetry was 4.4 s (p 〈 0.01). Analysis at different saturation levels showed finger probe responses to be significantly slower than ear probe responses at saturations equal to and above 91% (p 〈 0.05). At saturation levels of 90% or less no significant difference in probe response times were found.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2044.1992.tb01945.x
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Comparison of CLA with BPT, SPT, and RAST in children with asthma (1992)
    Oxford, UK : Blackwell Publishing Ltd
    Allergy 47 (1992), S. 0 
    Details
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Bronchial provocation tests (BPT) with allergen extracts were performed in 82 children with asthma, and the results were compared with the chemiluminescent assay (CLA), the radio-allergo-sorbent-test (RAST) and skin prick test (SPT). It was found that CLA matched BPT with a concordance of 87% (77–93%), RAST with a concordance of 74% (64–83%) and SPT with 80% (70–88%). Most often, CLA and RAST gave similar results, although their classes did not match precisely.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1398-9995.1992.tb02246.x
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    Paper (German National Licenses)
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