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  • Springer  (9)
  • American Physical Society (APS)
  • 1990-1994  (9)
  • 1991  (9)
  • 1
    Electronic Resource
    Electronic Resource
    Chitingehalt von höheren Pilzen (1991)
    Springer
    European food research and technology 193 (1991), S. 36-38 
    Details
    ISSN: 1438-2385
    Source: Springer Online Journal Archives 1860-2000
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Description / Table of Contents: Zusammenfassung Der Chitingehalt der Fruchtkörper (in einigen Fällen von Hüten und Stielen) einiger höherer Pilzarten aus verschiedenen Standorten von Ungarn wur-de untersucht. Es wurde festgestellt: l. DieAphyllophoraley-Arten, dies sind holzzerstörende, sogenannte xilo-phage Pilze, haben einen niedrigeren Chitingehalt. Die anderen (Boletales, Agaricales, Russulales) Arten zeigen einen signifikant höheren Chitingehalt (etwa 8–9%, bezogen auf Trockenmasse) in den Fruchtkörpern. 2. Die Unterschiede im Chitingehalt der verschiedenen Pilzgruppen werden nicht mit der unterschiedlichen systematischen Zugehörigkeit, sondern mit den verschiedenen Ernährungstypen (holzzerstörende, saprotrophe und Mykorrhizapilze) erklärt. Die holzzerstörenden Pilzarten haben einen signifikant niedrigen, die anderen einen höheren Chitingehalt. 3. Obwohl nur einige Hut- und Stielproben analysiert wurden, wurde in Hüten ein höherer, in Stielen ein niedrigerer Chitingehalt nachgewiesen. 4. Die Chitingehalte der untersuchten Pilzarten sind auch im Hinblick auf die Verdaulichkeit und damit die Verwendbarkeit der einzelnen, häufigen eßbaren Pilzarten bedeutsam.
    Notes: Summary The chitin content of fruit bodies (in some cases caps and stipes) of some higher fungi from different parts of Hungary have been analysed. The following results were obtained. 1. TheAphyllophorales species which are xilophagous, wood-rotting fungi, have a lower chitin content. The other species (Boletales, Agaricales, Russulales) have a significantly higher (8–9% of dry mass) chitin content in the fruit bodies. 2. The difference in chitin content of systematically different fungal groups can be explained by different types of nutrition (wood-rotting, saprotrophic and mykorrhiza fungi). The wood-rotting species have a significantly lower, the others a higher one. 3. Although only a few cap and stipe samples were analysed, in caps a higher chitin content was found and in stipes a lower one. 4. The chitin content of the in-vestigated fungal species is important information for the digestibility and use of some edible fungi.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01192014
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  • 2
    Electronic Resource
    Electronic Resource
    η Production in proton-nucleus reactions (1991)
    Springer
    The European physical journal 340 (1991), S. 51-57 
    Details
    ISSN: 1434-601X
    Keywords: 25.40.−h
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The production ofη-mesons in proton-nucleus reactions is analysed with respect to primary nucleon-nucleon (NN→NNη) and secondary pion-nucleon (πN→ηN) production processes on the basis of Hartree-Fock groundstate momentum distributions and free on-shell production processes. The folding model adopted compares well for meson production with more involved simulations based on VUU transport equations. Similar to K+ production in proton-nucleus reactions theη-mesons are primarily produced by theπN →ηN channel. However,η-mesons are absorbed in nuclei via excitation of the N* (1535) resonance which leads to strong distortions of the primordial spectra. On the other hand, the experimental mass dependence of the differential cross sections might yield information about the in-medium properties of this resonance.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01284480
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  • 3
    Electronic Resource
    Electronic Resource
    Buchbesprechung (1991)
    Springer
    Journal of molecular medicine 69 (1991), S. 841-841 
    Details
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01649456
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  • 4
    Electronic Resource
    Electronic Resource
    Buchbesprechung (1991)
    Springer
    Journal of molecular medicine 69 (1991), S. 942-942 
    Details
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01798548
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  • 5
    Electronic Resource
    Electronic Resource
    Plasma level monitoring of mitotane (o,p'-DDD) and its metabolite (o,p'-DDE) during long-term treatment of cushing's disease with low doses (1991)
    Springer
    European journal of clinical pharmacology 41 (1991), S. 259-261 
    Details
    ISSN: 1432-1041
    Keywords: Cushing's disease ; Mitotane ; o,p'-DDD ; long term treatment ; plasma monitoring ; adverse effects
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary. Mitotane (o,p'-DDD) can be used for the treatment of various adrenocortical diseases such as Cushing's syndrome, but the usual doses of 6–8 g per day are often associated with severe adverse effects. This paper reports the results of much lower doses of o,p'-DDD (0.5–2 g per day) in two patients with Cushing's disease over periods of 8 and 5 years, respectively, under concomitant monitoring of the plasma levels of the parent drug and its major metabolite, o,p'-DDE. It became apparent that o,p'-DDD and o,p'-DDE have a strong tendency to accumulate in the body due to their high lipophilicity. As a consequence, changes in dose regimens had long lag times before they were reflected in plasma levels and once an increase or decrease had started one had to be careful not to cause overshoot. Steady state plasma levels of o,p'-DDD between 5–10 μg/ml appeared sufficient to induce and to maintain remission of the disease, which was accompanied with normal cortisol levels in plasma and urine. DDD-levels below 5 μg/ml for several weeks may lead to relapses, whereas DDD-levels over 10 μg/ml gave rise to side effects. On the other hand, o,p'-DDE seemed inactive at levels up to 4 μg/ml in plasma.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00315440
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  • 6
    Electronic Resource
    Electronic Resource
    Potentiation of vascular smooth muscle cell activity by cyclosporin A (1991)
    Springer
    European journal of clinical pharmacology 41 (1991), S. 297-301 
    Details
    ISSN: 1432-1041
    Keywords: Vasoconstriction ; cyclosporin A ; vascular smooth muscle cells ; cytosolic free calcium ; cell proliferation ; phosphoinositide turnover ; cyclosporin A-induced hypertension ; PDGF ; adverse effect
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary Pretreatment of rat vascular smooth muscle cells with cyclosporin A caused concentration- and time-dependent enhancement of both angiotensin II- and platelet-derived growth factor-stimulated cellular functions, which may be related to a rise in vascular tone. In particular, cyclosporin A increased cytosolic free calcium, and augmented the agonist-induced formation of inositol polyphosphate. In addition, it markedly increased the sensitivity of the cells to platelet-derived growth factor-mediated stimulation of thymidine incorporation. The potentiation of vascular smooth muscle cell activity by cyclosporin A may be a novel mechanism by which it exerts an adverse vasoconstrictor effect.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00314955
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  • 7
    Electronic Resource
    Electronic Resource
    Pharmacokinetics and converting enzyme inhibition after morning and evening administration of oral enalapril to healthy subjects (1991)
    Springer
    European journal of clinical pharmacology 40 (1991), S. 95-99 
    Details
    ISSN: 1432-1041
    Keywords: Enalapril ; circadian pharmacokinetics ; ACE inhibition
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary Possible circadian changes in the pharmacokinetics and effect on serum angiotensin-converting enzyme (ACE) activity of the ACE inhibitor enalapril have been studied in 8 healthy subjects after oral ingestion of 10 mg enalapril maleate either at 08.00 h or 20.00 h. The time to peak serum concentration (tmax) of enalapril was increased after administration at 20.00 h compared to 08.00 h (2.4 h versus 1.3 h), where as other kinetic parameters were not significantly altered. The 24 h-kinetics of the active metabolite enalaprilat did not differ significantly between the two treatments, but the area under the curve (AUC (0–24)) and the peak serum concentration (Cmax) were slightly higher after intake at 20.00 h. The relationship between the measured serum enalaprilat level and the degree of inhibition of serum ACE was the same after both treatments. Overall, the evening and morning administration of enalapril did not differ markedly in the pharmacokinetics and the time course of ACE inhibition.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00315146
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  • 8
    Electronic Resource
    Electronic Resource
    Role of sulfhydryl groups in phospholipid methylation reactions of cardiac sarcolemma (1991)
    Springer
    Molecular and cellular biochemistry 103 (1991), S. 85-96 
    Details
    ISSN: 1573-4919
    Keywords: rat heart ; sarcolemma ; S-adenosyl-L-methionine ; phospholipid N-methylation ; neutral lipid methylation ; sulfhydryl groups
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract The effect of reagents that modify sulfur-containing amino acid residues in the phosphatidylethanolamine N-methyltransferase was studied in the isolated rat cardiac sarcolemma by employing S-adenosyl-L-[methyl-3H]methionine as a methyl donor. Dithiothreitol protected the sulfhydryl groups in the membrane and caused a concentration- and time-dependent increase of phospholipid N-methylation at three different catalytic sites. This stimulation was highest (9-fold) in the presence of 1 MM MgCl2 and 0.1 µM S-adenosyl-L-[methyl-3H]methionine at pH 8.0 (catalytic site 1), and was associated with an enhancement of Vmax without changes in Km for the methyl donor. Thiol glutathione was less stimulatory than dithiothreitol; glutathione disulfide inhibited the phosphatidylethanolamine N-methylation by 50%. The alkylating reagents, N-ethylmaleimide and methylmethanethiosulfonate, inhibited the N-methylation with IC5O of 6.9 and 14.1 µM, respectively; this inhibition was prevented by 1 mM dithiothreitol. These results indicate a critical role of sulfhydryl groups for the activity of the cardiac sarcolemmal phosphatidylethanolamine N-methyltransferase and suggest that this enzyme system in cardiac sarcolemma may be controlled by the glutathione/glutathione disulfide redox state in the cell.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00229596
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  • 9
    Electronic Resource
    Electronic Resource
    Identification and bioassay of sex pheromone components of carob moth,Ectomyelois ceratoniae (Zeller) (1991)
    Springer
    Journal of chemical ecology 17 (1991), S. 1973-1988 
    Details
    ISSN: 1573-1561
    Keywords: Flight tunnel ; gas chromatography-electrophysiology ; mass ; spectrometry ; aldehydes ; (Z,E)-9,11,13-tetradecatrienal ; (Z,E)-9,11-tetra-decadienal ; (Z)-9-tetradecenal ; pheromone ; Lepidoptera ; Pyralidae
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract Three sex pheromone components of the carob moth were isolated and identified from the extract of female pheromone glands, using a variety of techniques including coupled gas chromatographic-electroantennographic recordings, coupled gas chromatographic-mass spectrometric analysis, microozonolysis, electroantennographic assays of monounsaturated standards, wind-tunnel bioassays, and field trials. The major component was identified as (Z,E)-9,11,13-tetradecatrienal, a novel lepidopterous pheromone component structure. Two minor components, either one of which improves the upwind flight response of males when blended with the major component, were identified as (Z,E)-9,11-tetradecadienal, and (Z)-9-tetra-decenal.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00992582
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