ISSN:
1522-9602
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Mathematics
Notes:
Abstract A class of non-linear similarity functionss 1 has been proposed for comparing subalignments of biological sequences. The distribution of maximals 1-similarities is well approximated by the extreme value distribution. The significance levels ofs 1 are studied for a variety of nucleotide frequency distributions as well as for several matrices of amino acid substitution costs. Also, the significance levels ofs 1 are explored for comparing three biological sequences. Several previously described subalignments of bovine proenkephalin and porcine prodynorphin are shown to be highly significant.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02459979
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