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  • Artikel  (8)
  • Polymer and Materials Science  (4)
  • Hypertension  (2)
  • Captopril  (1)
  • Coarctatio aortae
  • General Chemistry
  • Human
  • Lens
  • Organic Chemistry
  • 1990-1994  (3)
  • 1985-1989  (5)
  • 1980-1984
  • 1965-1969
  • 1960-1964
  • 1993  (3)
  • 1985  (5)
Publikationsart
  • Artikel  (8)
Schlagwörter
Verlag/Herausgeber
Erscheinungszeitraum
  • 1990-1994  (3)
  • 1985-1989  (5)
  • 1980-1984
  • 1965-1969
  • 1960-1964
Jahr
  • 1
    Digitale Medien
    Digitale Medien
    Springer
    Journal of molecular medicine 63 (1985), S. 361-363 
    ISSN: 1432-1440
    Schlagwort(e): Primary aldosteronism ; Captopril ; Spironolactone ; Renin-angiotensin ; Converting-enzyme ; Secondary hypertension
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary In three patients with primary aldosteronism, the acute effect of a single dose of captopril on the elevated mean arterial blood pressure (MAP) was studied before and after 4 weeks of treatment with spironolactone. Before spironolactone therapy, captopril did not cause any drop in MAP. Four weeks later, after an oral daily dose of 400 mg spironolactone, MAP was still elevated in all three patients, though electrolyte abnormalities were fully corrected. Since plasma renin activity (PRA) was increased to values above the normal range, the acute effect of captopril on MAP was tested again. A single dose of 25 mg captopril then caused a fall in MAP to normal. These data reveal the conversion from a renin-independent to a renindependent kind of hypertension after spironolactone therapy in three patients with primary aldosteronism syndrome. This might be of pathogenetic and therapeutic interest.
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 2
    ISSN: 1432-1440
    Schlagwort(e): Na+/H+ antiport ; Hypertension ; Diabetic nephropathy ; Hereditary factors
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary The incidence of diabetic nephropathy in patients with insulin-dependent diabetes mellitus (IDDM) may depend on factors other than the quality of diabetes control. Hypertension is an additional factor associated with a high degree of renal involvement in IDDM. One abnormality consistantly observed in various tissues of patients with essential hypertension is enhanced activity of the Na+/H+ antiport. In the present study we have therefore studied platelet antiport activity in 41 healthy subjects (control), in 22 patients with untreated essential hypertension (EH), and in 35 normotensive IDDM patients (type 1). Of these patients 17 exhibited signs of diabetic nephropathy (group 1) while 18 had no evidence for renal involvement of IDDM in spite of a duration of IDDM of at least 10 years (group 2). The two IDDM patient groups were undistinguishable with respect to age, body mass index, and arterial blood pressure (group 1, 117.9±2.4/78.4±1.5 mmHg; group 2, 113.9±3.6/76.1±1.8 mmHg). Antiporter activity was determined from the rate of cell volume changes induced by propionic acid. Platelet Na+/H+ exchange activity averaged 23.43±0.43 10−3·s−1 in control subjects and was markedly elevated in EH (28.38±0.62 10−3·s−1 P〈0.01). Antiport activity in group 2 patients without nephropathy averaged 24.54±0.57 10−3·s−1 and was undistinguishable from the control group. However, platelet Na+/H+ antiport activity was significantly stimulated in group 1 patients with nephropathy as compared to group 2(26.95±0.73 10−3. s−1 ; P〈0.025). Our results show that renal involvement in IDDM is associated with enhanced activity of the platelet Na+/H+ antiport.
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 3
    Digitale Medien
    Digitale Medien
    Springer
    Journal of molecular medicine 63 (1985), S. 762-764 
    ISSN: 1432-1440
    Schlagwort(e): Phlebotomy ; Hypertension
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary In 15 essential hypertensives resistant against a standard triple combination of antihypertensive drugs phlebotomy was performed. Mean arterial pressure was lowered from 140.1±12.2 mm Hg to 123.8±14.9 mm Hg after 14 days. No serious side effects were observed. The duration of the hypoptensive effect of phlebotomy was about 4 weeks. Phlebotomy can be used in addition to drug treatment in resistant essential hypertension.
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 4
    Digitale Medien
    Digitale Medien
    New York, NY : Wiley-Blackwell
    Journal für Praktische Chemie/Chemiker-Zeitung 327 (1985), S. 399-410 
    ISSN: 0021-8383
    Schlagwort(e): Chemistry ; Organic Chemistry
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Notizen: Photoinduced Electron Transfer between Arenediazonium Cations and AnionsAnions X⊖ can act as donors in electron transfer reactions to photoexcited arenediazonium ions. The yield of the arene formed in this reaction increases with decreasing electrochemical oxidation potential EoxD of X⊖ (X⊖ = BPh4⊖, Br⊖, HOOC—COO⊖, Cl⊖, BF4⊖). The oxidized donor X· (Cl·, ·COO⊖) and aryl radicals Ar· benig intermediates of the reductive dediazoniation of ArN2⊖ can be detected by spin trapping with nitrosodurene (ND) and phenyl-tert-butylnitrone (PBN). A solvent effect in the electron transfer reaction is interpreted in terms of ion pairing, where the electron transfer is favored by preorientation and a short distance between the electron donor and the acceptor previous to excitation of ArN2⊖ by light.
    Zusätzliches Material: 5 Ill.
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 5
    Digitale Medien
    Digitale Medien
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 65 (1993), S. 1088-1090 
    ISSN: 0009-286X
    Schlagwort(e): Chemistry ; Polymer and Materials Science
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 6
    Digitale Medien
    Digitale Medien
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 57 (1985), S. 395-409 
    ISSN: 0009-286X
    Schlagwort(e): Chemistry ; Polymer and Materials Science
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: Dosage of solids and liquids. Dosage of reaction components is an important step in chemical engineering processes. In an age of increasing automation, the development of dosage procedures is highly topical; electronics and data processing have long made inroads into dosage procedures. However, today's more stringent demands with regard to pressure, temperature, viscosity, and abrasion necessitate intensified research and development efforts. The present article considers mainly volumetric and geometric dosage methods. The many types of metering pumps cover a large area of dosage of liquids. Minimal flow rates, pressures up to several 1000 bar, and also dangerous and difficult fluids can all be safely handled. Leakproof designs with membranes, tubes, or bellows as displacement devices are particularly important nowadays. Volumetric dosage of solids requires establishment of a reproducible packing density. The survey considers the principle methods of dosage (also against pressure) with special emphasis on screw dosage. Gravimetric dosage methods are extremely reliable and accurate but generally require volumetric systems for energy supply. Especially when used in combination with metering pumps or screw dosage, differential balances have numerous possible applications.
    Zusätzliches Material: 25 Ill.
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 7
    ISSN: 0009-286X
    Schlagwort(e): Chemistry ; Polymer and Materials Science
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: Pressure Pulsations Caused by Reciprocating Pumps in Piping Systems. The safe design of piping installations for reciprocating pumps requires proper knowledge about the pump/installation interaction. In many cases critical resonance effects can be avoided by proper piping geometry or improved pump performance with respect to the volumetric efficiency (primary measures). Normally it is necessary to use various secondary dampening methods which can influence the acoustics of the piping system. Several examples of experimental computer simulations of damper action - upstream and downstream - are presented for fluidand gas-filled damper versions. The influence of entry geometry of the dampers is explained, hints on the proper geometry of the entries are given and the effects of various dampers and their influence on the total acoustics are discussed. Special reference is made to the effect of orifices as dissipative and acoustic elements in piping systems. The investigation shows the importance of analyzing of the total system of pump, piping installation and vessels or reactors and the application of computer simulation for piping design.
    Zusätzliches Material: 28 Ill.
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 8
    Digitale Medien
    Digitale Medien
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 57 (1985), S. 218-229 
    ISSN: 0009-286X
    Schlagwort(e): Chemistry ; Polymer and Materials Science
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: Leakfree oscillating positive-displacement pumps - state of the art and trends of development. Leak- and maintenance-free oscillating positive-displacement pumps are very important for avoiding pollution and improving the reliability of plants. Technical progress in the field of hydraulic diaphragm- and tube-pumps for high pressures are explained. The actual data (pressure, efficiency, temperature) and experience with different fluids are surveyed. The various hydraulic control systems, the diaphragm design, and methods for rupture-control are compared. Further development trends are explained.
    Zusätzliches Material: 20 Ill.
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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