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Thymus rudiment of the athymic nude mouse (1975)

HOLUB, M. ; ROSSMANN, P. ; TLASKALOVA, H. ; [et al.]

[s.l.] : Nature Publishing Group

Nature 256 (1975), S. 491-493

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ISSN: 1476-4687

Source: Nature Archives 1869 - 2009

Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics

Notes: [Auszug] Fig. 1 The lymphoepithelial rudiment of a nu/nu (BALB/c) male aged 122 d. H & E, x 160. Fig. 2 Sensitivity of cells from euthymic mouse thymus and nujnu lymphoepithelial rudiment (thymus?), spleen and lymph nodes to anti-6 antibodies. Solid columns, anti-6-C3H+ complement; hatched columns, C ...

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1038/256491a0

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Experimental immune complex glomerulopathy: Immunomorphological aspects and correlations with human disease (1975)

Rossmann, P. ; Říha, I. ; Hajdu, I.

Springer

International urology and nephrology 7 (1975), S. 219-233

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ISSN: 1573-2584

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Abstract Thirteen rabbits received parenteral injections of human serum albumin (HSA) in regular doses and intervals during 6–32 weeks. The antigen load elicited immune responses of variable degree, giving a good correlation with the extent and quality of immune complex (IMC) deposition, as shown by immunological methods, electron and fluorescence microscopy and by histoautoradiography. Morphology of immune deposits (IMD) depended on the composition of the IMC and produced a continuous scale of glomerular involvement, ranging from minimal and focal to massive and diffuse deposition. Probable rudimentary traces of IMD were apparent in the ultrastructure even in animals with negative results of both immunological and immunfluorescence examinations. The relationships are discussed between experimental IMC-induced glomerulopathy on the one hand, and some problems of development and bioptic evaluation of human glomerulonephritis.