In:
Tuberculosis and Respiratory Diseases, The Korean Academy of Tuberculosis and Respiratory Diseases, Vol. 12, No. 1 ( 1962-12-01), p. 13-21
Abstract:
The problem, how to manage so-callcd chronic far-advanced drug resistant pulmonary tuberculosis patients, attracted the new attention of chest clinicians and investigators and many trails have been made to solve the problem.Since the advent of P. Z. A. by Kushner (1952) many secondary antituhcrculous drugs includingC.S., K.M. and 1314 TH appeared in rapid succession and seemed to give new enthusiasm.The author has made a study on the effect of various secondary anti-tuberculous drugs including C.S., P.Z.A,K.M. Abcid , and T.M. in the group of chronic pulmonary tuberculosis patients resistant against three principle drugs (S.M. ,I.N.H., P.A.S.) and summarised the results as follows.1) Among 96 patients of medical cases.Roentgenological improvement was made in 39.0% for C.S. group, 28.6% for P.Z.A., 9.1% for K.M.,8.7% for Abcid, respectively and most of the improvement was only slight in degree.2) The sputum conversion rate was very poor, only two cases, one is C.S. group another is P.Z.A. group.3) The symptomatic improvements were most excellent in C.S. group, that is. about two third of the patients among C.S. group showed improvement of one or more subjective symptoms.4) The side reactions were most frequent in P.Z.A. group, and two cases of severe joint pain and one casc of aunte hepatitis were most haza dous. The occurrence of the neuropsychiatric disorder with C.S. and the damagc of Vlll nerve with K. M. not significant in this sludy.5) Among 75 patients of surgery combined, the sputum conversion rate was 100% except of dead cases immediately after operation.6) The occurrence of complication after operation was 34.5% in the principle drug resistant group and it was as high as other reports. (Adrews. Sweetman) Over-all operation mortality rate was 5.06%.7) The over-all conclusion of this study is the secondary anti-tuberculosis drugs at present have some effects in the management of chronic. principle drug resistant pulmonary tuberculosis patient but not so much optimistic as many author's reports.
Type of Medium:
Online Resource
ISSN:
1738-3536
,
2005-6184
DOI:
10.4046/trd.1962.12.1.13
Language:
English
Publisher:
The Korean Academy of Tuberculosis and Respiratory Diseases
Publication Date:
1962
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