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  • Fisheries  (2)
  • Clonidine allergy  (1)
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  • 1980-1984  (1)
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  • 1984  (1)
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  • 1
    Digitale Medien
    Digitale Medien
    Springer
    Journal of molecular medicine 62 (1984), S. 925-930 
    ISSN: 1432-1440
    Schlagwort(e): Transdermal therapeutic systems (TTS) ; Clonidine ; Essential hypertension ; Skin allergy ; Clonidine allergy
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Skin patches of a clonidine transdermal therapeutic system (clonidine-TTS) with a constant release rate of either 0.1 or 0.2 mg clonidine/24 h continuously over 7 days were used in 32 essential hypertensives. These self-adhesive drug delivery systems (3.5 cm2), which were affixed to the upper outer arm, were changed by the patients at weekly intervals. During a mean observation period of 7 months (range 1–19 months) transdermal clonidine reduced the blood pressure from 162±15/107±5 mmHg to normal values (diastolic ≦95 mmHg) in 63% of our patients. However, chronic use of clonidine-TTS was accompanied by a high frequency of contact dermatitis (type IV allergy) in nearly half of our patients (n=15, 47%). In 11 of these 15 patients transdermal clonidine administration had to be stopped because of intolerable local skin reactions (pruritus, erythema, vesiculation, and/or infiltration). Subsequent patch testing with all components of clonidine-TTS was performed in eight cases. Whereas in seven cases an allergic contact dermatitis to clonidine was found, only one patient showed an allergy to another component of clonidine-TTS (polyisobutylene). We conclude that this strikingly high incidence of local allergic skin reactions limits the use of clonidine-TTS in essential hypertension.
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 2
    facet.materialart.
    Unbekannt
    In:  http://aquaticcommons.org/id/eprint/8700 | 403 | 2012-06-07 14:51:15 | 8700 | United States National Marine Fisheries Service
    Publikationsdatum: 2021-06-25
    Beschreibung: The broad distribution of Pacific sardine (Sardinops sagax)along the Pacif ic coast of North America makes it difficult for fisheries managers to identify regionalstocks of this dominant small pelagic species. An investigation of morphometric characteristics of otoliths ofPacific sardine across most of their range revealed regional differences in populations. In a survey of over 2000 otoliths, all ages (with an emphasis on age-1 recruits) were compared. Principal components analysis, multivariate analysis of variance, and a novel method derived from regression and residuals calculations, termedperimeter-weight profiles (PWPs), revealed otolith similarities and differences. The results of the differentapproaches to statistical comparisons did not always agree. Sardine otoliths from Mexican waters were generallylighter and more lobate than those from U.S. and Canadian populations. Age-1 otoliths from northern California in 2006–07 tended to be heavier and smoother than those from other areas, including year-class cohorts from southern California. Comparisons of age-groups and year-classes of northern California otoliths with the use of the PWP models indicated signif icant trends in year-to-year patterns. In conjunction with other established indices of populationstructure, otolith PWPs are a useful tool for identifying local and regional stocks of Pacific sardine and may helpdistinguish populations of other fish species as well.
    Schlagwort(e): Biology ; Ecology ; Fisheries
    Repository-Name: AquaDocs
    Materialart: article , TRUE
    Format: application/pdf
    Format: application/pdf
    Format: 402-415
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 3
    facet.materialart.
    Unbekannt
    In:  http://aquaticcommons.org/id/eprint/12092 | 9601 | 2013-10-29 19:52:00 | 12092 | Gulf and Caribbean Fisheries Institute
    Publikationsdatum: 2021-07-01
    Schlagwort(e): Fisheries ; GCFI
    Repository-Name: AquaDocs
    Materialart: conference_item
    Format: application/pdf
    Format: application/pdf
    Format: 56-63
    Standort Signatur Einschränkungen Verfügbarkeit
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