In:
Chemistry – A European Journal, Wiley, Vol. 27, No. 19 ( 2021-04), p. 5890-5896
Abstract:
Chiral α‐amino acids play critical roles in the metabolic process in nearly all life forms. So far, chiral recognition of α‐amino acids has mainly focused on the determination of l / d enantiomers. Herein, selection of planar chiral conformations between water‐soluble pillar[5]arene WP5 and pillar[6]arene WP6 was observed due to α‐side chain or ethyl ester moieties of l ‐α‐amino acid ethyl ester hydrochlorides binding with WP5 and WP6 , respectively. Therefore, α‐side chain and ethyl ester moieties of l ‐α‐amino acid ethyl ester hydrochlorides were recognized by observing the induced CD signal and its inversion. This is a rare example of being able to detect the chiral region around α‐carbon of a chiral α‐amino acid molecule.
Type of Medium:
Online Resource
ISSN:
0947-6539
,
1521-3765
DOI:
10.1002/chem.202004003
Language:
English
Publisher:
Wiley
Publication Date:
2021
detail.hit.zdb_id:
1478547-X
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