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  • 1
    Online Resource
    Online Resource
    Cambridge University Press (CUP) ; 2019
    In:  Journal of Navigation Vol. 72, No. 2 ( 2019-03), p. 290-306
    In: Journal of Navigation, Cambridge University Press (CUP), Vol. 72, No. 2 ( 2019-03), p. 290-306
    Abstract: Clustering methods that use a similarity measurement for evaluating vessel trajectories are important for mining spatial distribution information in water transportation. To better measure the similarity of vessel trajectories, a novel similarity measure is proposed based on the dynamic time warping distance, which considers the course change of track points and the meaning at the route level. Parallel experiments were conducted based on a month of Automatic Identification System (AIS) data collected from the Zhoushan Islands area, China. After evaluation of the accuracy and the cluster degree, the novel measure demonstrated its capabilities for distinguishing different vessel trajectories and detecting similar vessel trajectories with high accuracy and has a better performance compared to some existing methods.
    Type of Medium: Online Resource
    ISSN: 0373-4633 , 1469-7785
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2019
    detail.hit.zdb_id: 2015312-0
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  • 2
    Online Resource
    Online Resource
    Institute of Electrical and Electronics Engineers (IEEE) ; 2022
    In:  IEEE Transactions on Intelligent Transportation Systems Vol. 23, No. 8 ( 2022-8), p. 13745-13757
    In: IEEE Transactions on Intelligent Transportation Systems, Institute of Electrical and Electronics Engineers (IEEE), Vol. 23, No. 8 ( 2022-8), p. 13745-13757
    Type of Medium: Online Resource
    ISSN: 1524-9050 , 1558-0016
    Language: Unknown
    Publisher: Institute of Electrical and Electronics Engineers (IEEE)
    Publication Date: 2022
    detail.hit.zdb_id: 2034300-0
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  • 3
    Online Resource
    Online Resource
    Wiley ; 2023
    In:  Therapeutic Apheresis and Dialysis Vol. 27, No. 3 ( 2023-06), p. 383-393
    In: Therapeutic Apheresis and Dialysis, Wiley, Vol. 27, No. 3 ( 2023-06), p. 383-393
    Abstract: The anti‐inflammatory effect of vitamin D in patients with chronic kidney disease (CKD) remains controversial. This study aimed to conduct a meta‐analysis of randomized controlled trials to assess the anti‐inflammatory effects of vitamin D in patients with CKD. Methods We searched Embase, Science Citation Index, Medline, Cochrane Central Register of Controlled Trials, and Clinical Trial Registries for randomized controlled trials that comparing vitamin D with control groups for inflammatory markers in patients with CKD. Subgroup analysis was performed based on treatment duration (short‐term treatment, long‐term treatment), type of patients (predialysis CKD, dialysis, kidney transplant), 25(OH)D levels (25(OH)D deficiency or normal 25(OH)D), and methods of C‐reactive protein (CRP) test (standard CRP test or high‐sensitivity CRP [hs‐CRP] test). Results Eighteen trials with 1834 patients were included in the present study. There were no significant differences between the vitamin D group and control group for CRP (WMD, −0.3 mg/L; 95% CI, −0.81 to 0.22, p  = 0.26, I 2  = 62%), interleukin‐6 (IL‐6) (WMD, −1.07 pg/ml; 95% CI, −2.44 to 0.30, p  = 0.12, I 2  = 52%), and tumor necrosis factor‐α (TNF‐α) (WMD, −0.00 pg/ml; 95% CI, −0.36 to 0.35, p  = 0.99, I 2  = 0%) in patients with CKD. Subgroup analysis showed vitamin D can improve hs‐CRP, but not CRP. The rest of subgroups showed that no significant differences were observed between the vitamin D group and control group based on 25(OH)D levels, treatment duration, and predialysis CKD or dialysis patients. Conclusion This meta‐analysis demonstrates that vitamin D supplementation does not have anti‐inflammatory effects in CKD patients. Well‐designed randomized controlled trials with large samples are required to confirm this conclusion. It is still needed to find an effective treatment for inflammatory state in CKD.
    Type of Medium: Online Resource
    ISSN: 1744-9979 , 1744-9987
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 2010864-3
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  • 4
    In: Sensors, MDPI AG, Vol. 23, No. 18 ( 2023-09-12), p. 7828-
    Abstract: The traditional LDPC encoding and decoding system is characterized by low throughput and high resource consumption, making it unsuitable for use in cost-efficient, energy-saving sensor networks. Aiming to optimize coding complexity and throughput, this paper proposes a combined design of a novel LDPC code structure and the corresponding overlapping decoding strategies. With regard to structure of LDPC code, a CCSDS-like quasi-cyclic parity check matrix (PCM) with uniform distribution of submatrices is constructed to maximize overlap depth and adapt the parallel decoding. In terms of reception decoding strategies, we use a modified 2-bit Min-Sum algorithm (MSA) that achieves a coding gain of 5 dB at a bit error rate of 10−6 compared to an uncoded BPSK, further mitigating resource consumption, and which only incurs a slight loss compared to the standard MSA. Moreover, a shift-register-based memory scheduling strategy is presented to fully utilize the quasi-cyclic characteristic and shorten the read/write latency. With proper overlap scheduling, the time consumption can be reduced by one third per iteration compared to the non-overlap algorithm. Simulation and implementation results demonstrate that our decoder can achieve a throughput up to 7.76 Gbps at a frequency of 156.25 MHz operating eight iterations, with a two-thirds resource consumption saving.
    Type of Medium: Online Resource
    ISSN: 1424-8220
    Language: English
    Publisher: MDPI AG
    Publication Date: 2023
    detail.hit.zdb_id: 2052857-7
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  • 5
    In: BioMed Research International, Hindawi Limited, Vol. 2022 ( 2022-10-22), p. 1-12
    Abstract: Background. Persistent inflammation has been recognized as an important comorbid condition in patients with chronic kidney disease (CKD) and is associated with many complications, mortality, and progression of CKD. Previous studies have not drawn a clear conclusion about the anti-inflammatory effects of statins in CKD. This meta-analysis is aimed at assessing the anti-inflammatory effects of statins therapy in patients with CKD. Methods. A comprehensive literature search was conducted in these databases (Medline, Embase, Cochrane library, and clinical trials) to identify the randomized controlled trials that assess the anti-inflammatory effects of statins. Subgroup, sensitivity, and trim-and-fill analysis were conducted to determine the robustness of pooled results of the primary outcome. Results. 25 eligible studies with 7921 participants were included in this meta-analysis. The present study showed that statins therapy was associated with a decreased C-reactive protein (CRP) (-2.06 mg/L; 95% CI: -2.85 to -1.27, p 〈 0.01 ). Subgroup, sensitivity, and trim-and-fill analysis showed that the pooled results of CPR were stable. Conclusion. This meta-analysis demonstrates that statins supplementation has anti-inflammatory effects in patients with CKD. Statins exert an anti-inflammatory effect that is clinically important in improving complications, reducing mortality, and slowing progression in CKD. We believe that the benefits of statins to CKD are partly due to their anti-inflammatory effects. However, stains usually are prescribed in the CKD patients with dyslipidemia, whether statins can reduce inflammation in CKD patients with normal serum lipid needed to explore in the future. Therefore, we suggest that randomized clinical trials need to assess the effect of statins in CKD patients with normal serum lipid. Whether statins can be prescribed for aiming to inhibit inflammation in CKD also needed further study. Trial Registration. The study protocol was registered in the International Prospective Register of Systematic Reviews (PROSPERO); registration number: CRD42022310334.
    Type of Medium: Online Resource
    ISSN: 2314-6141 , 2314-6133
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2022
    detail.hit.zdb_id: 2698540-8
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  • 6
    Online Resource
    Online Resource
    Hindawi Limited ; 2022
    In:  Evidence-Based Complementary and Alternative Medicine Vol. 2022 ( 2022-3-21), p. 1-5
    In: Evidence-Based Complementary and Alternative Medicine, Hindawi Limited, Vol. 2022 ( 2022-3-21), p. 1-5
    Abstract: Acute kidney injury (AKI), a common condition associated with a high mortality rate, is characterized by declined glomerular filtration rate, retention of nitrogen products, and disturbances in balance of water, electrolyte, and acid-base. Up to date, there is no effective treatment for AKI. Despite the continuous improvement in blood purification techniques, a considerable proportion of patients with AKI still progress to end-stage renal disease. These patients with advanced stage of end-stage renal disease will require long-term renal replacement therapy, which places a heavy burden on the family and the society. In recent years, the use of traditional Chinese medicine (TCM) in AKI management has been gradually increasing. Clinical evidence has demonstrated that three-month treatment with TCM produced better clinical outcomes in terms of clinical effectiveness rate and improvement in renal function (serum creatinine, neutrophil gelatinase-associated lipocalin, and cystatin C) compared with Western medicine. Rhubarb is a commonly used herb in TCM for the treatment of AKI. The main active component of rhubarb is emodin, which was first recorded in Shennong’s Classic of Materia Medica. It has been shown that emodin has a variety of pharmacological activities including antibacterial, anti-inflammatory, antiulcer, and immunosuppressive effects. Emodin has been found to be effective against renal fibrosis and has been widely studied for its effects on kidney diseases such as diabetic nephropathy, renal fibrosis, and AKI. Moreover, promising results have been obtained from these studies. In this study, the results obtained from research on the use of emodin for AKI treatment has been reviewed.
    Type of Medium: Online Resource
    ISSN: 1741-4288 , 1741-427X
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2022
    detail.hit.zdb_id: 2148302-4
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  • 7
    Online Resource
    Online Resource
    Elsevier BV ; 2023
    In:  Clinica Chimica Acta Vol. 548 ( 2023-08), p. 117518-
    In: Clinica Chimica Acta, Elsevier BV, Vol. 548 ( 2023-08), p. 117518-
    Type of Medium: Online Resource
    ISSN: 0009-8981
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2023
    detail.hit.zdb_id: 1499920-1
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  • 8
    In: Learned Publishing, Wiley, Vol. 35, No. 1 ( 2022-01), p. 30-45
    Abstract: This article investigates the research data policies of China's scholarly journals to provide a regional perspective. In total, 1243 science, technology, and medicine (STM) journals in the Chinese Science Citation Database (CSCD) were examined in June and July of 2021. The findings show that the existence and attitudinal strength of the research data policies of China's scholarly journals are weak overall, but differences exist across journals with different languages, publishers, disciplines, access models and metrics. A large imbalance exists between English‐language journals and Chinese‐language journals in setting their research data policies. The existence and attitudinal strength of the research data policies of journals co‐published by Western publishers and Chinese publishers are much stronger than those of journals published solely by Chinese publishers. In terms of discipline, journals belonging to the life sciences have stronger attitudes towards research data sharing. Open access model journals and hybrid model journals are better than subscription model journals in opening and sharing research data. The higher the impact factor (IF) and CiteScore of a journal, the more likely the journal is to have data policies.
    Type of Medium: Online Resource
    ISSN: 0953-1513 , 1741-4857
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2022
    detail.hit.zdb_id: 2018596-0
    SSG: 24,1
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  • 9
    Online Resource
    Online Resource
    Oxford University Press (OUP) ; 2021
    In:  Clinical Kidney Journal Vol. 14, No. 11 ( 2021-11-08), p. 2444-2445
    In: Clinical Kidney Journal, Oxford University Press (OUP), Vol. 14, No. 11 ( 2021-11-08), p. 2444-2445
    Type of Medium: Online Resource
    ISSN: 2048-8505 , 2048-8513
    Language: English
    Publisher: Oxford University Press (OUP)
    Publication Date: 2021
    detail.hit.zdb_id: 2656786-6
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  • 10
    In: Journal of Diabetes Research, Hindawi Limited, Vol. 2021 ( 2021-2-5), p. 1-12
    Abstract: Background. Diabetic nephropathy (DN) is one of the most common complications of diabetes mellitus and is a major cause of end-stage kidney disease. Cordyceps sinensis (Cordyceps, Dong Chong Xia Cao) is a widely applied ingredient for treating patients with DN in China, while the molecular mechanisms remain unclear. This study is aimed at revealing the therapeutic mechanisms of Cordyceps in DN by undertaking a network pharmacology analysis. Materials and Methods. In this study, active ingredients and associated target proteins of Cordyceps sinensis were obtained via Traditional Chinese Medicine Systems Pharmacology Database (TCMSP) and Swiss Target Prediction platform, then reconfirmed by using PubChem databases. The collection of DN-related target genes was based on DisGeNET and GeneCards databases. A DN-Cordyceps common target interaction network was carried out via the STRING database, and the results were integrated and visualized by utilizing Cytoscape software. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses were performed to determine the molecular mechanisms and therapeutic effects of Cordyceps on the treatment of DN. Results. Seven active ingredients were screened from Cordyceps, 293 putative target genes were identified, and 85 overlapping targets matched with DN were considered potential therapeutic targets, such as TNF, MAPK1, EGFR, ACE, and CASP3. The results of GO and KEGG analyses revealed that hub targets mainly participated in the AGE-RAGE signaling pathway in diabetic complications, TNF signaling pathway, PI3K-Akt signaling pathway, and IL-17 signaling pathway. These targets were correlated with inflammatory response, apoptosis, oxidative stress, insulin resistance, and other biological processes. Conclusions. Our study showed that Cordyceps is characterized as multicomponent, multitarget, and multichannel. Cordyceps may play a crucial role in the treatment of DN by targeting TNF, MAPK1, EGFR, ACE, and CASP3 signaling and involved in the inflammatory response, apoptosis, oxidative stress, and insulin resistance.
    Type of Medium: Online Resource
    ISSN: 2314-6753 , 2314-6745
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2021
    detail.hit.zdb_id: 2711897-6
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