In:
Arteriosclerosis, Thrombosis, and Vascular Biology, Ovid Technologies (Wolters Kluwer Health), Vol. 26, No. 12 ( 2006-12), p. 2652-2659
Abstract:
A global-survey of TNF-α-signaling in ECs revealed that VCAM-1 expression is highly induced in a process dependent on PI3-K, GATA, HDAC, and new protein synthesis. HDAC inhibition abrogated monocyte adhesion to inflamed endothelium suggesting that HDAC, specifically HDAC3, might be useful for the attenuation of the inflammatory response in ECs.
Type of Medium:
Online Resource
ISSN:
1079-5642
,
1524-4636
DOI:
10.1161/01.ATV.0000247247.89787.e7
Language:
English
Publisher:
Ovid Technologies (Wolters Kluwer Health)
Publication Date:
2006
detail.hit.zdb_id:
1494427-3
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