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  • Wiley  (10)
  • Yang, Yuejin  (10)
  • 1
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    Stress hyperglycemia ratio and long‐term mortality after acute myocardial infarction in patients with and without diabetes: A prospective, nationwide, and multicentre registry
    Wiley ; 2022
    In:  Diabetes/Metabolism Research and Reviews Vol. 38, No. 7 ( 2022-10)
    Details
    In: Diabetes/Metabolism Research and Reviews, Wiley, Vol. 38, No. 7 ( 2022-10)
    Abstract: To assess the predictive value of stress hyperglycemia ratio (SHR) for long‐term mortality after acute myocardial infarction (AMI) in patients with and without diabetes. Materials and Methods We evaluated 6892 patients with AMI from the prospective, nationwide, multicentre China Acute Myocardial Infarction registry, of which 2820 had diabetes, and the remaining 4072 were nondiabetic patients. Patients were divided into high SHR and low SHR groups according to the optimal cutoff values of SHR to predict long‐term mortality for diabetic and nondiabetic patients, respectively. The primary endpoint was all‐cause mortality at 2 years. Results The optimal cutoff values of SHR for predicting 2‐year mortality were 1.20 and 1.08 for the diabetic and nondiabetic population, respectively. Overall, patients with high SHR were significantly associated with higher all‐cause mortality compared with those with low SHR, in both diabetic patients (18.5% vs. 9.7%; hazard ratio [HR] 2.01, 95% confidence interval 1.63–2.49) and nondiabetic patients (12.0% vs. 6.4%; HR 1.95, 95%CI 1.57–2.41). After the potential confounders were adjusted, high SHR was significantly associated with higher risks of long‐term mortality in both diabetic (adjusted HR 1.73, 95%CI 1.39–2.15) and nondiabetic (adjusted HR 1.63, 95%CI 1.30–2.03) patients. Moreover, adding SHR to the original model led to a slight albeit significant improvement in C‐statistic, net reclassification, and integrated discrimination regardless of diabetic status. Conclusions This study demonstrated a strong positive association between SHR and long‐term mortality in patients with AMI with and without diabetes, suggesting that SHR should be considered a useful marker for risk stratification in these patients. Trial registration: ClinicalTrials.gov NCT01874691.
    Type of Medium: Online Resource
    ISSN: 1520-7552 , 1520-7560
    URL: Issue
    URL: Article
    DOI: 10.1002/dmrr.v38.7
    DOI: 10.1002/dmrr.3562
    Language: English
    Publisher: Wiley
    Publication Date: 2022
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  • 2
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    Association of symptom status, myocardial viability, and clinical/anatomic risk on long‐term outcomes after chronic total occlusion percutaneous coronary intervention
    Wiley ; 2021
    In:  Catheterization and Cardiovascular Interventions Vol. 97, No. S2 ( 2021-05), p. 996-1008
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    In: Catheterization and Cardiovascular Interventions, Wiley, Vol. 97, No. S2 ( 2021-05), p. 996-1008
    Abstract: This study aimed to examine the association of less‐certain indication of chronic total occlusion percutaneous coronary intervention (CTO‐PCI) with subsequent clinical outcomes. Background The impact of patient symptoms, myocardial viability, and clinical and anatomic risk on long‐term outcomes is underdetermined. Methods Consecutive patients undergoing CTO‐PCI at a large‐volume single center between 2010 and 2013 were included. Central adjudication was used to assess the appropriateness of three prespecified indications. The primary outcome was the 5‐year composite endpoint of death or myocardial infarction (MI). Results Of 2,659 patients with 2,735 CTO lesions, the 348 (13.1%) asymptomatic patients, 164 (6.2%) patients without viable myocardium in the CTO territory, and 306 (11.5%) patients in whom the Synergy between PCI with Taxus and Cardiac Surgery Score II favored coronary artery bypass grafting (CABG) had higher 5‐year death or MI compared with the rest patients in each category (12.0% vs. 8.6%, p = .04; 16.3% vs. 8.5%, p   〈  .0001; 12.2% vs. 8.6%, p = .03), respectively. Multivariable regression analysis demonstrated that without symptom (hazard ratio: 1.51; 95% confidence interval: 1.06–2.15; p = .02), non‐viable myocardium in CTO territory (hazard ratio: 1.77; 95% confidence interval: 1.16–2.72; p = .009), and deemed more favorable for CABG (hazard ratio:1.54; 95% confidence interval: 1.04–2.28; p = .03), but not the technical success (hazard ratio:0.85; 95% confidence interval: 0.62–1.18; p = .34), were independent predictors for the primary endpoint. Conclusions In this large cohort of CTO‐PCI, those who were asymptomatic, non‐viable myocardium in the CTO territory, or deemed more favorable for CABG were associated with higher risk of long‐term mortality or MI.
    Type of Medium: Online Resource
    ISSN: 1522-1946 , 1522-726X
    URL: Issue
    URL: Article
    DOI: 10.1002/ccd.v97.S2
    DOI: 10.1002/ccd.29577
    Language: English
    Publisher: Wiley
    Publication Date: 2021
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  • 3
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    Long‐term clinical outcomes in transradial versus transfemoral access for left main percutaneous coronary intervention
    Wiley ; 2021
    In:  Catheterization and Cardiovascular Interventions Vol. 97, No. S2 ( 2021-05), p. 1009-1015
    Details
    In: Catheterization and Cardiovascular Interventions, Wiley, Vol. 97, No. S2 ( 2021-05), p. 1009-1015
    Abstract: The present study compared 10‐year clinical outcomes between transradial access (TRA) and transfemoral access (TFA) for left main (LM) percutaneous coronary intervention (PCI). Background There are limited data regarding the long‐term safety and efficacy of TRA for LM PCI. Methods This retrospective study evaluated consecutive patients who underwent unprotected LM PCI between January 2004 and December 2008 at Fu Wai Hospital. The exclusion criteria were age of less than 18 years and presentation with acute myocardial infarction. The primary endpoint was major adverse cardiac or cerebrovascular events (MACCE), which was defined as a composite of all‐cause death, myocardial infarction, stroke, and any revascularization at the 10‐year follow‐up. Results Among 913 eligible patients, TRA was used for 417 patients (45.7%) and TFA was used for 496 patients (54.3%). The 30‐day clinical outcomes were similar between the two groups. Results from the 10‐year follow‐up revealed that MACCE occurred in 180 patients (46.7%) from the TRA group and in 239 patients (51.2%) from the TFA group (log‐rank p = .3). The TRA and TFA groups also had low and comparable cumulative rates of all‐cause death (14.6% vs. 17.3%, log‐rank p = .56) and cardiac death (7.9% vs. 9.1%, log‐rank p = .7). Conclusion The present study revealed no significant differences in long‐term clinical outcomes when TRA or TFA were used for LM PCI.
    Type of Medium: Online Resource
    ISSN: 1522-1946 , 1522-726X
    URL: Issue
    URL: Article
    DOI: 10.1002/ccd.v97.S2
    DOI: 10.1002/ccd.29586
    Language: English
    Publisher: Wiley
    Publication Date: 2021
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  • 4
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    Intracoronary delivery of autologous bone marrow mononuclear cells radiolabeled by 18F-fluoro-deoxy-glucose: Tissue distribution and impact on post-infarct swine hearts
    Wiley ; 2007
    In:  Journal of Cellular Biochemistry Vol. 102, No. 1 ( 2007-09-01), p. 64-74
    Details
    In: Journal of Cellular Biochemistry, Wiley, Vol. 102, No. 1 ( 2007-09-01), p. 64-74
    Type of Medium: Online Resource
    ISSN: 0730-2312 , 1097-4644
    URL: Issue
    URL: Journal
    URL: Article
    DOI: 10.1002/jcb.v102:1
    DOI: 10.1002/(ISSN)1097-4644
    DOI: 10.1002/jcb.21277
    Language: English
    Publisher: Wiley
    Publication Date: 2007
    detail.hit.zdb_id: 1479976-5
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  • 5
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    Predictors for adverse outcomes of patients with recanalized chronic total occlusion lesion
    Wiley ; 2021
    In:  European Journal of Clinical Investigation Vol. 51, No. 2 ( 2021-02)
    Details
    In: European Journal of Clinical Investigation, Wiley, Vol. 51, No. 2 ( 2021-02)
    Abstract: It is ill‐defined which factors affect the prognosis of patients with recanalized chronic total occlusion (CTO). This study sought to investigate predictors for adverse outcome in such a cohort with long‐time follow‐up. Methods From 2010 to 2013, patients with successfully recanalized CTO were included. The primary endpoint was a composite of all‐cause death, myocardial infarction or target vessel revascularization (TVR). The secondary endpoints were TVR and target lesion revascularization (TLR). Results A total of 1987 patients were enrolled and 1806 (90.6%) subjects completed 5‐year follow‐up. Multivariate Cox analysis revealed that age ≥ 75 years (HR,1.70; 95% CI, 1.09‐2.64; P  = .02), left ventricular ejection fraction 〈 40% (HR, 1.94; 95% CI, 1.02‐3.69; P  = .04) and residual SYNTAX score (HR, 1.02; 95% CI, 1.01‐1.04; P  = .01) were predictors for the primary endpoint. Non‐LAD CTO (HR, 1.82; 95% CI, 1.23‐2.70; P   〈  .01), J‐CTO score (HR, 1.31; 95% CI, 1.11‐1.54; P   〈  .01) and residual SYNTAX score (HR, 1.02; 95% CI, 1.00‐1.04; P  = .04) were independently related to TVR. Non‐LAD CTO, high J‐CTO score and residual SYNTAX score was also correlated with TLR. Conclusions Advanced age, left ventricular dysfunction and residual SYNTAX score were predictors for composite cardiovascular events in patients with CTO after revascularization. Those with non‐LAD CTO, high J‐CTO and residual SYNTAX score had higher risk for revascularization.
    Type of Medium: Online Resource
    ISSN: 0014-2972 , 1365-2362
    URL: Issue
    URL: Article
    DOI: 10.1111/eci.v51.2
    DOI: 10.1111/eci.13368
    Language: English
    Publisher: Wiley
    Publication Date: 2021
    detail.hit.zdb_id: 2004971-7
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  • 6
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    Integrating the residual SYNTAX score to improve the predictive ability of the age, creatinine, and ejection fraction (ACEF) score for cardiac mortality in percutaneous coronary intervention patients
    Wiley ; 2020
    In:  Catheterization and Cardiovascular Interventions Vol. 95, No. S1 ( 2020-02), p. 534-541
    Details
    In: Catheterization and Cardiovascular Interventions, Wiley, Vol. 95, No. S1 ( 2020-02), p. 534-541
    Abstract: To improve the prognostic value of the age, creatinine, and ejection fraction (ACEF) score following percutaneous coronary intervention (PCI) by integrating the residual SYNTAX score (rSS). Background ACEF score was proposed for predicting the operative mortality risk in elective cardiac operations and has been validated in numerous studies. However, it does not incorporate coronary lesion‐based variables for risk assessment of patients who undergo PCI. Methods Overall, 10,072 patients who underwent PCI at our hospital in 2013 were enrolled. The endpoint was 2‐year cardiac death after PCI, defined as death that was not attributed to a non‐cardiac cause. ACEF‐rSS was constructed with incremental weights attributed to the ACEF score and rSS according to their estimated coefficients. Results 2‐year cardiac death occurred in 63 patients (0.63%). In multivariable analyses, the ACEF score and rSS  〉  8 were independently associated with the risk of cardiac death. ACEF‐rSS was computed as age (years)/ejection fraction (%) + 1 (if creatinine ≥2.0 mg/dl) + 1 (if rSS 〉 8). The discrimination of ACEF‐rSS was significantly better than that of the ACEF score based on receiver operating characteristic (ROC) curve analysis and integrated discrimination improvement (IDI) ( C ‐statistics = 0.835 vs. 0.776 for ACEF‐rSS and ACEF score, respectively, p = .029; IDI = 0.014, p 〈  .001). Compared with all other SYNTAX‐derived risk scores, ACEF‐rSS had significantly better discrimination ability based on ROC curve analysis, net reclassification improvement, and IDI. Conclusions Combining the ACEF score with rSS to produce the ACEF‐rSS enhanced the predictive ability for long‐term cardiac mortality.
    Type of Medium: Online Resource
    ISSN: 1522-1946 , 1522-726X
    URL: Issue
    URL: Article
    DOI: 10.1002/ccd.v95.S1
    DOI: 10.1002/ccd.28673
    Language: English
    Publisher: Wiley
    Publication Date: 2020
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  • 7
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    Can “true bifurcation lesion” actually be regarded as an independent risk factor of acute side branch occlusion after main vessel stenting?: A retrospective analysis of 1,200 consecutive bifurcation lesions in a single center
    Wiley ; 2016
    In:  Catheterization and Cardiovascular Interventions Vol. 87, No. S1 ( 2016-03), p. 554-563
    Details
    In: Catheterization and Cardiovascular Interventions, Wiley, Vol. 87, No. S1 ( 2016-03), p. 554-563
    Abstract: True bifurcation lesion (TBL) is conventionally considered as a risk factor for acute side branch (SB) occlusion when using a single‐stent strategy to treat bifurcation lesions. The impact of TBLs on acute SB occlusion after main vessel (MV) stenting was investigated. Methods A total of 1,170 consecutive patients with 1,200 bifurcation lesions undergoing one‐stent or provisional two‐stent techniques were studied. The TBLs were divided into two groups depending on their Medina classification. Multivariate logistic regression analysis was performed to identify independent predictors of acute SB occlusion. According to the median diameter of stenosis (DS) in the MV and the SB after pre‐dilatation, the TBL group was divided into three subgroups: subgroup I (DS of both the MV and the SB 〈 their respective medians), subgroup II (DS of one of the MV or the SB ≥its respective median), and subgroup III (DS of both the MV and the SB ≥their respective medians). The incidences of SB occlusion in these three subgroups were compared. Results Multivariate logistic regression analysis showed that TBL occurrence was not independently predictive of SB occlusion. Based on subgroup analysis, the incidence of SB occlusion in subgroup I (7.4%) was significantly lower than that in subgroup II (13.0%) and subgroup III (22.0%) ( P  = 0.025). However, there was no significant difference in the incidence of SB occlusion between TBL subgroup I (7.4%) and the non‐TBL group (5.1%) ( P  = 0.53). Conclusions TBL occurrence cannot be regarded as an independent predictor of acute SB occlusion after MV stenting. © 2016 Wiley Periodicals, Inc.
    Type of Medium: Online Resource
    ISSN: 1522-1946 , 1522-726X
    URL: Issue
    URL: Article
    DOI: 10.1002/ccd.v87.S1
    DOI: 10.1002/ccd.26403
    Language: English
    Publisher: Wiley
    Publication Date: 2016
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  • 8
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    Validation of contemporary risk scores in predicting coronary thrombotic events and major bleeding in patients with acute coronary syndrome after drug‐eluting stent implantations
    Wiley ; 2018
    In:  Catheterization and Cardiovascular Interventions Vol. 91, No. S1 ( 2018-02-15), p. 573-581
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    In: Catheterization and Cardiovascular Interventions, Wiley, Vol. 91, No. S1 ( 2018-02-15), p. 573-581
    Abstract: We aimed to assess the prognostic ability of the ST score, DAPT score, and PARIS score in a Chinese population. Background Recently, several risk scores predicting the long‐term risk of coronary thrombotic events [CTE, defined as the composite of definite or probable stent thrombosis (ST) and myocardial infarction] and bleeding have been developed and initially validated in Western populations. Methods A total of 6,088 consecutive patients with acute coronary syndrome (mean age 58.3 ± 10.4; women 23.1%) treated with drug‐eluting stents in 2013 at our single institution were enrolled. We calculated risk scores and evaluated their performance for predicting definite or probable ST, CTE and major bleeding (MB, defined as the occurrence of a Bleeding Academic Research Consortium type 3 or 5 bleed). The prognostic value of risk scores was assessed by receiver‐operating characteristic curves. Results The ST score, DAPT score, and PARIS score all showed unsatisfactory discrimination to predict 2‐year or 1‐ to 2‐year ST and CTE ( c ‐statistic = 0.51–0.59). With respect to bleeding outcomes, the PARIS score showed unsatisfactory discrimination in predicting 2‐year MB ( c ‐statistic = 0.56); the DAPT score performed slightly better than the PARIS score in predicting occurrence of later MB events between 1 and 2 years, whereas its discriminative capacity was only modest ( c ‐statistic = 0.71). Conclusions The current three risk scores, derived and initially validated in Western populations, may not be applicable to the Chinese population, although DAPT score was determined to be a modestly accurate quantitative tool for prediction of later MB.
    Type of Medium: Online Resource
    ISSN: 1522-1946 , 1522-726X
    URL: Issue
    URL: Article
    DOI: 10.1002/ccd.v91.S1
    DOI: 10.1002/ccd.27468
    Language: English
    Publisher: Wiley
    Publication Date: 2018
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  • 9
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    A novel technique for coronary bifurcation intervention: Double rewire crush technique and its clinical outcomes after 2 years of follow‐up
    Wiley ; 2019
    In:  Catheterization and Cardiovascular Interventions Vol. 93, No. S1 ( 2019-02-15), p. 851-858
    Details
    In: Catheterization and Cardiovascular Interventions, Wiley, Vol. 93, No. S1 ( 2019-02-15), p. 851-858
    Abstract: To describe procedural details of the double rewire (DR) crush technique, a novel modified crush technique, and report the clinical outcomes of patients who underwent the procedure. Background In the management of complex bifurcation lesions, there is a need to use elective two‐stent techniques that stent the side branch (SB) before main vessel (MV) stenting and keep SB open. Methods We studied 48 patients with 49 bifurcation lesions who underwent percutaneous coronary intervention (PCI) using the DR‐crush technique between January and December 2013. Baseline, postprocedural, and follow‐up quantitative coronary angiographic analyses were performed. Procedural characteristics and clinical outcomes at follow‐up were assessed. Results Majority of the patients (60.4%, 29/48) had acute coronary syndrome. Most bifurcation lesions (77.6%, 38/49) were classified as Medina 1, 1, 1. Final kissing balloon inflation was successfully performed in all patients. After PCI, MV and SB of all patients had Thrombolysis In Myocardial Infarction 3 blood flow. None of the patients had MV or SB diameter stenosis ≥50% after PCI. At a mean follow‐up period of 2.4 years, target vessel revascularization occurred in 2.1% and myocardial infarction in 2.1%. No deaths occurred in this period. Conclusions The DR‐crush technique is feasible in coronary bifurcation stenting. Patients who underwent this procedure had relatively low incidence of adverse events. Larger studies are warranted for further confirmation of the findings.
    Type of Medium: Online Resource
    ISSN: 1522-1946 , 1522-726X
    URL: Issue
    URL: Article
    DOI: 10.1002/ccd.v93.S1
    DOI: 10.1002/ccd.28066
    Language: English
    Publisher: Wiley
    Publication Date: 2019
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  • 10
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    How bifurcation angle impacts the fate of side branch after main vessel stenting: A retrospective analysis of 1,200 consecutive bifurcation lesions in a single center
    Wiley ; 2015
    In:  Catheterization and Cardiovascular Interventions Vol. 85, No. S1 ( 2015-03), p. 706-715
    Details
    In: Catheterization and Cardiovascular Interventions, Wiley, Vol. 85, No. S1 ( 2015-03), p. 706-715
    Abstract: We aimed to investigate the effect of bifurcation angle (BA) on side branch (SB) occlusion after main vessel (MV) stenting. Background : BA is thought to impact the risk of SB occlusion in coronary bifurcation patients undergoing percutaneous coronary intervention (PCI). Methods A total of 1,171 consecutive patients with 1,200 bifurcation lesions undergoing one stent or provisional two stent techniques were studied. The lesions were divided into low angle and high angle groups using the median BA (52°). Multivariate logistic regression analysis was performed to identify independent predictors of SB occlusion. Results SB occlusion occurred in 88 (7.33%) of 1,200 bifurcation lesions treated with the one stent technique or MV stenting first strategy. The rate of SB occlusion was significantly higher in the high angle group (63/600, 10.5%) than the low angle group (25/600, 4.2%) ( P   〈  0.001). The rate of SB occlusion increased significantly across quartiles of BA as follows: from 3.63% in the first quartile of BA, to 4.71% in quartile II, to 8.14% in quartile III to 12.97% in quartile IV ( P   〈  0.001). Multivariable analysis showed that high angle was an independent predictor of SB occlusion (odds ratio: 1.026, 95% confidence intervals: 1.014–1.037, P   〈  0.001). Plaque distribution at the same side of SB, MV Thrombolysis in Myocardial Infarction flow grade before stenting, pre‐procedural diameter stenosis of bifurcation core, diameter ratio between MV/SB and diameter stenosis of SB before MV stenting were also independent predictors of SB occlusion. Conclusions High BA was an independent predictor of SB occlusion after MV stenting. The occlusion risk of SB with a high BA should not be ignored. © 2015 Wiley Periodicals, Inc.
    Type of Medium: Online Resource
    ISSN: 1522-1946 , 1522-726X
    URL: Issue
    URL: Article
    DOI: 10.1002/ccd.v85.S1
    DOI: 10.1002/ccd.25858
    Language: English
    Publisher: Wiley
    Publication Date: 2015
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