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  • Yang, Jing  (778)
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  • 1
    In: Autophagy, Informa UK Limited, Vol. 17, No. 1 ( 2021-01-02), p. 1-382
    Type of Medium: Online Resource
    ISSN: 1554-8627 , 1554-8635
    Language: English
    Publisher: Informa UK Limited
    Publication Date: 2021
    detail.hit.zdb_id: 2262043-6
    SSG: 12
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  • 2
    In: Intensive Care Medicine, Springer Science and Business Media LLC, Vol. 47, No. 2 ( 2021-02), p. 160-169
    Type of Medium: Online Resource
    ISSN: 0342-4642 , 1432-1238
    RVK:
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2021
    detail.hit.zdb_id: 1459201-0
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  • 3
    In: Biochemical and Biophysical Research Communications, Elsevier BV, Vol. 463, No. 4 ( 2015-08), p. 1250-1256
    Type of Medium: Online Resource
    ISSN: 0006-291X
    RVK:
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2015
    detail.hit.zdb_id: 1461396-7
    SSG: 12
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  • 4
    Online Resource
    Online Resource
    Walter de Gruyter GmbH ; 2018
    In:  Clinical Chemistry and Laboratory Medicine (CCLM) Vol. 56, No. 3 ( 2018-2-23), p. 485-491
    In: Clinical Chemistry and Laboratory Medicine (CCLM), Walter de Gruyter GmbH, Vol. 56, No. 3 ( 2018-2-23), p. 485-491
    Abstract: DNMT3A is a DNA methyltransferase that acts in de novo methylation. Aberrant expression of DNMT3A has been reported in several human diseases, including myelodysplastic syndrome (MDS). However, the pattern of DNMT3A methylation remains unknown in MDS. Methods: The present study was aimed to investigate the methylation status of DNMT3A intragenic differentially methylated region 2 (DMR2) using real-time quantitative methylation-specific PCR and analyze its clinical significance in MDS. Results: Aberrant hypomethylation of DNMT3A was found in 57% (51/90) MDS cases. There were no significant differences in age, sex, white blood cell counts, platelet counts, hemoglobin counts and World Health Organization, International Prognostic Scoring System and karyotype classifications between DNMT3A hypomethylated and DNMT3A hypermethylated groups. However, the patients with DNMT3A hypomethylation had shorter overall survival time than those without DNMT3A hypomethylation (11 months vs. 36 months, p=0.033). Multivariate analysis confirmed the independent adverse impact of DNMT3A hypomethylation in MDS. Conclusions: Our data suggest that DNMT3A DMR2 hypomethylation may be a negative prognostic hallmark in MDS.
    Type of Medium: Online Resource
    ISSN: 1437-4331 , 1434-6621
    Language: English
    Publisher: Walter de Gruyter GmbH
    Publication Date: 2018
    detail.hit.zdb_id: 1492732-9
    SSG: 15,3
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  • 5
    In: International Journal of Genomics, Hindawi Limited, Vol. 2014 ( 2014), p. 1-8
    Abstract: The Delta-12 oleate desaturase gene ( FAD2 -1), which converts oleic acid into linoleic acid, is the key enzyme determining the fatty acid composition of seed oil. In this study, we inhibited the expression of endogenous Delta-12 oleate desaturase GmFad2-1b gene by using antisense RNA in soybean Williams 82. By employing the soybean cotyledonary-node method, a part of the cDNA of soybean GmFad2-1b 801 bp was cloned for the construction of a pCAMBIA3300 vector under the soybean seed promoter BCSP . Leaf painting, LibertyLink strip, PCR, Southern blot, qRT-PCR, and fatty acid analysis were used to detect the insertion and expression of GmFad2-1b in the transgenic soybean lines. The results indicate that the metabolically engineered plants exhibited a significant increase in oleic acid (up to 51.71%) and a reduction in palmitic acid (to 〈 3%) in their seed oil content. No structural differences were observed between the fatty acids of the transgenic and the nontransgenic oil extracts.
    Type of Medium: Online Resource
    ISSN: 2314-436X , 2314-4378
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2014
    detail.hit.zdb_id: 2711883-6
    SSG: 12
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  • 6
    In: Circulation, Ovid Technologies (Wolters Kluwer Health), Vol. 146, No. 4 ( 2022-07-26), p. 303-315
    Abstract: More than one-fifth of the world’s population consumes Chinese cuisines regularly, but no evidence-based healthy diets fitting the Chinese food culture are available for implementation. Methods: A multicenter, patient- and outcome assessor–blind, randomized feeding trial was conducted among 265 participants with 130 to 159 mm Hg baseline systolic blood pressure (SBP) for 4 major Chinese cuisines (Shangdong, Huaiyang, Cantonese, Szechuan). After a 7-day run-in period on a control diet matching the usual local diets, participants were randomized to continue with the control diet or the cuisine-based Chinese heart-healthy diet for another 28 days. The primary outcome was SBP, and secondary outcomes included diastolic blood pressure and food preference score. Linear regression models were used to estimate the intervention effects and adjustments for the center. The incremental cost per 1 mm Hg reduction in SBP was also calculated. Results: A total of 265 participants were randomized (135 on the Chinese heart-healthy diet and 130 on the control diet), with 52% women, mean age of 56.5±9.8 years, and mean SBP and diastolic blood pressure of 139.4±8.3 and 88.1±8.0 mm Hg, respectively, at baseline. The change in SBP and diastolic blood pressure from baseline to the end of the study in the control group was –5.0 (95% CI, –6.5 to –3.5) mm Hg and –2.8 (95% CI, –3.7 to –1.9) mm Hg, respectively. The net difference of change between the 2 groups in SBP and diastolic blood pressure were –10.0 (95% CI, –12.1 to –7.9) mm Hg and –3.8 (95% CI, –5.0 to –2.5) mm Hg, respectively. The effect size did not differ among cuisines ( P for interaction=0.173). The mean food preference score was 9.5 (with 10 the best preferred) at baseline, and the net change during intervention was 0.1 (95% CI, –0.1 to 0.2; P =0.558). The incremental cost-effectiveness ratio per 1 mm Hg SBP reduction was CNY 0.4 (USD 0.06) per day. No difference in the number of adverse events was found between the 2 groups ( P =0.259), and none of the adverse events was associated with the intervention. Conclusions: The Chinese heart-healthy diet is effective, palatable, and cost-effective in reducing blood pressure in Chinese adults with high blood pressure, with a clinically significant effect applicable across major Chinese cuisine cultures. Registration: URL: https://www.clinicaltrials.gov ; Unique identifier: NCT03882645.
    Type of Medium: Online Resource
    ISSN: 0009-7322 , 1524-4539
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2022
    detail.hit.zdb_id: 1466401-X
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  • 7
    Online Resource
    Online Resource
    Springer Science and Business Media LLC ; 2016
    In:  Tumor Biology Vol. 37, No. 7 ( 2016-7), p. 8951-8960
    In: Tumor Biology, Springer Science and Business Media LLC, Vol. 37, No. 7 ( 2016-7), p. 8951-8960
    Type of Medium: Online Resource
    ISSN: 1010-4283 , 1423-0380
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2016
    detail.hit.zdb_id: 605825-5
    detail.hit.zdb_id: 1483579-4
    SSG: 12
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  • 8
    In: Fungal Diversity, Springer Science and Business Media LLC, Vol. 105, No. 1 ( 2020-11), p. 319-575
    Abstract: Freshwater Dothideomycetes are a highly diverse group of fungi, which are mostly saprobic in freshwater habitats worldwide. They are important decomposers of submerged woody debris and leaves in water. In this paper, we outline the genera of freshwater Dothideomycetes with notes and keys to species. Based on multigene analyses and morphology, we introduce nine new genera, viz . Aquimassariosphaeria , Aquatospora , Aquihelicascus , Fusiformiseptata , Neohelicascus , Neojahnula , Pseudojahnula , Purpureofaciens , Submersispora ; 33 new species, viz . Acrocalymma bipolare , Aquimassariosphaeria kunmingensis , Aquatospora cylindrica , Aquihelicascus songkhlaensis , A. yunnanensis , Ascagilis submersa , A. thailandensis , Bambusicola aquatica , Caryospora submersa , Dictyocheirospora thailandica , Fusiformiseptata crocea , Helicosporium thailandense , Hongkongmyces aquaticus , Lentistoma aquaticum , Lentithecium kunmingense , Lindgomyces aquaticus , Longipedicellata aquatica , Neohelicascus submersus , Neohelicomyces dehongensis , N. thailandicus , Neohelicosporium submersum , Nigrograna aquatica , Occultibambusa kunmingensis , Parabambusicola aquatica , Pseudoasteromassaria aquatica , Pseudoastrosphaeriella aquatica , Pseudoxylomyces aquaticus , Purpureofaciens aquatica , Roussoella aquatica , Shrungabeeja aquatica , Submersispora variabilis , Tetraploa puzheheiensis , T. yunnanensis ; 16 new combinations, viz. Aquimassariosphaeria typhicola , Aquihelicascus thalassioideus , Ascagilis guttulaspora , A. queenslandica , A. seychellensis , A. sunyatsenii , Ernakulamia xishuangbannaensis , Neohelicascus aquaticus , N. chiangraiensis , N. egyptiacus , N. elaterascus , N. gallicus , N. unilocularis , N. uniseptatus , Neojahnula australiensis , Pseudojahnula potamophila ; 17 new geographical and habitat records, viz. Aliquandostipite khaoyaiensis , Aquastroma magniostiolata , Caryospora aquatica , C. quercus , Dendryphiella vinosa , Ernakulamia cochinensis , Fissuroma neoaggregatum , Helicotruncatum palmigenum , Jahnula rostrata , Neoroussoella bambusae , N. leucaenae , Occultibambusa pustula , Paramonodictys solitarius , Pleopunctum pseudoellipsoideum , Pseudocapulatispora longiappendiculata , Seriascoma didymosporum , Shrungabeeja vadirajensis and ten new collections from China and Thailand, viz. Amniculicola guttulata , Aquaphila albicans , Berkleasmium latisporum , Clohesyomyces aquaticus , Dictyocheirospora rotunda , Flabellascoma fusiforme , Pseudoastrosphaeriella bambusae , Pseudoxylomyces elegans , Tubeufia aquatica and T. cylindrothecia . Dendryphiella phitsanulokensis and Tubeufia roseohelicospora are synonymized with D. vinosa and T. tectonae , respectively. Six orders, 43 families and 145 genera which belong to freshwater Dothideomycetes are reviewed. Of these, 46 genera occur exclusively in freshwater habitats. A world map illustrates the distribution of freshwater Dothideomycetes.
    Type of Medium: Online Resource
    ISSN: 1560-2745 , 1878-9129
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2020
    detail.hit.zdb_id: 2424484-3
    SSG: 12
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  • 9
    In: Fungal Diversity, Springer Science and Business Media LLC, Vol. 100, No. 1 ( 2020-01), p. 5-277
    Abstract: Fungal diversity notes is one of the important journal series of fungal taxonomy that provide detailed descriptions and illustrations of new fungal taxa, as well as providing new information of fungal taxa worldwide. This article is the 11th contribution to the fungal diversity notes series, in which 126 taxa distributed in two phyla, six classes, 24 orders and 55 families are described and illustrated. Taxa in this study were mainly collected from Italy by Erio Camporesi and also collected from China, India and Thailand, as well as in some other European, North American and South American countries. Taxa described in the present study include two new families, 12 new genera, 82 new species, five new combinations and 25 new records on new hosts and new geographical distributions as well as sexual-asexual reports. The two new families are Eriomycetaceae (Dothideomycetes, family incertae sedis ) and Fasciatisporaceae ( Xylariales , Sordariomycetes). The twelve new genera comprise Bhagirathimyces ( Phaeosphaeriaceae ), Camporesiomyces ( Tubeufiaceae ), Eriocamporesia ( Cryphonectriaceae ), Eriomyces ( Eriomycetaceae ), Neomonodictys ( Pleurotheciaceae ), Paraloratospora ( Phaeosphaeriaceae ), Paramonodictys ( Parabambusicolaceae ), Pseudoconlarium (Diaporthomycetidae, genus incertae sedis ), Pseudomurilentithecium ( Lentitheciaceae ), Setoapiospora ( Muyocopronaceae ), Srinivasanomyces ( Vibrisseaceae ) and Xenoanthostomella ( Xylariales , genera incertae sedis ). The 82 new species comprise Acremonium chiangraiense , Adustochaete nivea , Angustimassarina camporesii , Bhagirathimyces himalayensis , Brunneoclavispora camporesii , Camarosporidiella camporesii , Camporesiomyces mali , Camposporium appendiculatum , Camposporium multiseptatum , Camposporium septatum , Canalisporium aquaticium , Clonostachys eriocamporesiana , Clonostachys eriocamporesii , Colletotrichum hederiicola , Coniochaeta vineae , Conioscypha verrucosa , Cortinarius ainsworthii , Cortinarius aurae , Cortinarius britannicus , Cortinarius heatherae , Cortinarius scoticus , Cortinarius subsaniosus , Cytospora fusispora , Cytospora rosigena , Diaporthe camporesii , Diaporthe nigra , Diatrypella yunnanensis , Dictyosporium muriformis , Didymella camporesii , Diutina bernali , Diutina sipiczkii , Eriocamporesia aurantia , Eriomyces heveae , Ernakulamia tanakae , Falciformispora uttaraditensis , Fasciatispora cocoes , Foliophoma camporesii , Fuscostagonospora camporesii , Helvella subtinta , Kalmusia erioi , Keissleriella camporesiana , Keissleriella camporesii , Lanspora cylindrospora , Loratospora arezzoensis , Mariannaea atlantica , Melanographium phoenicis , Montagnula camporesii , Neodidymelliopsis camporesii , Neokalmusia kunmingensis , Neoleptosporella camporesiana , Neomonodictys muriformis , Neomyrmecridium guizhouense , Neosetophoma camporesii , Paraloratospora camporesii , Paramonodictys solitarius , Periconia palmicola , Plenodomus triseptatus , Pseudocamarosporium camporesii , Pseudocercospora maetaengensis , Pseudochaetosphaeronema kunmingense , Pseudoconlarium punctiforme , Pseudodactylaria camporesiana , Pseudomurilentithecium camporesii , Pseudotetraploa rajmachiensis , Pseudotruncatella camporesii , Rhexocercosporidium senecionis , Rhytidhysteron camporesii , Rhytidhysteron erioi , Septoriella camporesii , Setoapiospora thailandica , Srinivasanomyces kangrensis , Tetraploa dwibahubeeja , Tetraploa pseudoaristata , Tetraploa thrayabahubeeja , Torula camporesii , Tremateia camporesii , Tremateia lamiacearum , Uzbekistanica pruni , Verruconis mangrovei , Wilcoxina verruculosa , Xenoanthostomella chromolaenae and Xenodidymella camporesii . The five new combinations are Camporesiomyces patagoniensis , Camporesiomyces vaccinia , Camposporium lycopodiellae , Paraloratospora gahniae and Rhexocercosporidium microsporum . The 22 new records on host and geographical distribution comprise Arthrinium marii , Ascochyta medicaginicola , Ascochyta pisi , Astrocystis bambusicola , Camposporium pellucidum , Dendryphiella phitsanulokensis , Diaporthe foeniculina , Didymella macrostoma , Diplodia mutila , Diplodia seriata , Heterosphaeria patella , Hysterobrevium constrictum , Neodidymelliopsis ranunculi , Neovaginatispora fuckelii , Nothophoma quercina , Occultibambusa bambusae , Phaeosphaeria chinensis , Pseudopestalotiopsis theae , Pyxine berteriana , Tetraploa sasicola , Torula gaodangensis and Wojnowiciella dactylidis . In addition, the sexual morphs of Dissoconium eucalypti and Phaeosphaeriopsis pseudoagavacearum are reported from Laurus nobilis and Yucca gloriosa in Italy, respectively. The holomorph of Diaporthe cynaroidis is also reported for the first time.
    Type of Medium: Online Resource
    ISSN: 1560-2745 , 1878-9129
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2020
    detail.hit.zdb_id: 2424484-3
    SSG: 12
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  • 10
    Online Resource
    Online Resource
    American Society for Microbiology ; 2016
    In:  Journal of Virology Vol. 90, No. 12 ( 2016-06-15), p. 5561-5573
    In: Journal of Virology, American Society for Microbiology, Vol. 90, No. 12 ( 2016-06-15), p. 5561-5573
    Abstract: Due to enzootic infections in poultry and persistent human infections in China, influenza A (H7N9) virus has remained a public health threat. The Yangtze River Delta region, which is located in eastern China, is well recognized as the original source for H7N9 outbreaks. Based on the evolutionary analysis of H7N9 viruses from all three outbreak waves since 2013, we identified the Pearl River Delta region as an additional H7N9 outbreak source. H7N9 viruses are repeatedly introduced from these two sources to the other areas, and the persistent circulation of H7N9 viruses occurs in poultry, causing continuous outbreak waves. Poultry movements may contribute to the geographic expansion of the virus. In addition, the AnH1 genotype, which was predominant during wave 1, was replaced by JS537, JS18828, and AnH1887 genotypes during waves 2 and 3. The establishment of a new source and the continuous evolution of the virus hamper the elimination of H7N9 viruses, thus posing a long-term threat of H7N9 infection in humans. Therefore, both surveillance of H7N9 viruses in humans and poultry and supervision of poultry movements should be strengthened. IMPORTANCE Since its occurrence in humans in eastern China in spring 2013, the avian H7N9 viruses have been demonstrating the continuing pandemic threat posed by the current influenza ecosystem in China. As the viruses are silently circulated in poultry, with potentially severe outcomes in humans, H7N9 virus activity in humans in China is very important to understand. In this study, we identified a newly emerged H7N9 outbreak source in the Pearl River Delta region. Both sources in the Yangtze River Delta region and the Pearl River Delta region have been established and found to be responsible for the H7N9 outbreaks in mainland China.
    Type of Medium: Online Resource
    ISSN: 0022-538X , 1098-5514
    Language: English
    Publisher: American Society for Microbiology
    Publication Date: 2016
    detail.hit.zdb_id: 1495529-5
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