In:
Zeitschrift für Naturforschung C, Walter de Gruyter GmbH, Vol. 67, No. 5-6 ( 2012-6-1), p. 342-352
Abstract:
Cyclin-dependent kinases (CDKs) are serine/threonine kinases that play critical roles in the cell cycle regulation. Herein, we describe the identifi cation of a CDK gene from Apis cerana cerana, named AccCDK6. The full-length cDNA is 1,778 bp long, including an ORF of 1,380 bp that encodes a polypeptide of 459 amino acid residues. Multiple sequence alignment analysis showed that the predicted AccCDK6 sequence shares a high similarity with CDK6 genes of other species, and this protein may share an evolutionary predecessor with Drosophila CDK4. The expression patterns of the gene were also analysed, and the transcript was detected throughout the larval, pupal, and adult developmental stages. Furthermore, the expression level of the mRNA of the gene in adult workers was infl uenced by H 2 O 2 , ultraviolet (UV) light, temperature (42°C), HgCl 2 , and pyriproxyfen. These results indicate that AccCDK6 responds to multiple environmental stresses and may also participate in intracellular reactions of reactive oxygen species (ROS) and development processes in honey-bees
Type of Medium:
Online Resource
ISSN:
1865-7125
,
0939-5075
DOI:
10.1515/znc-2012-5-615
Language:
English
Publisher:
Walter de Gruyter GmbH
Publication Date:
2012
detail.hit.zdb_id:
2078107-6
SSG:
12
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