GLORIA

GEOMAR Library Ocean Research Information Access

X

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • Wu, Siying  (4)
  • 1
    Online Resource
    Online Resource
    Bacterial and Fungal Infections After Liver Transplantation: Microbial Epidemiology, Risk Factors for Infection and Death with Infection
    International Scientific Information, Inc. ; 2020
    In:  Annals of Transplantation Vol. 25 ( 2020-04-24)
    Details
    In: Annals of Transplantation, International Scientific Information, Inc., Vol. 25 ( 2020-04-24)
    Type of Medium: Online Resource
    ISSN: 2329-0358
    URL: Article
    DOI: 10.12659/AOT.921591
    Language: English
    Publisher: International Scientific Information, Inc.
    Publication Date: 2020
    detail.hit.zdb_id: 2393116-4
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 2
    Online Resource
    Online Resource
    Total Laboratory Automation and Three Shifts Reduce Turnaround Time of Cerebrospinal Fluid Culture Results in the Chinese Clinical Microbiology Laboratory
    Frontiers Media SA ; 2021
    In:  Frontiers in Cellular and Infection Microbiology Vol. 11 ( 2021-12-2)
    Details
    In: Frontiers in Cellular and Infection Microbiology, Frontiers Media SA, Vol. 11 ( 2021-12-2)
    Abstract: Total laboratory automation (TLA) has the potential to reduce specimen processing time, optimize workflow, and decrease turnaround time (TAT). The purpose of this research is to investigate whether the TAT of our laboratory has changed since the adoption of TLA, as well as to optimize laboratory workflow, improve laboratory testing efficiency, and provide better services of clinical diagnosis and treatment. Materials and Methods Laboratory data was extracted from our laboratory information system in two 6-month periods: pre-TLA (July to December 2019) and post-TLA (July to December 2020), respectively. Results The median TAT for positive cultures decreased significantly from pre-TLA to post-TLA (65.93 vs 63.53, P & lt;0.001). For different types of cultures, The TAT of CSF changed the most (86.76 vs 64.30, P =0.007), followed by sputum (64.38 vs 61.41, P & lt;0.001), urine (52.10 vs 49,57, P & lt;0.001), blood (68.49 vs 66.60, P & lt;0.001). For Ascites and Pleural fluid, there was no significant difference ( P & gt;0.05). Further analysis found that the incidence of broth growth only for pre-TLA was 12.4% (14/133), while for post-TLA, it was 3.4% (4/119). The difference was statistically significant ( P =0.01). The common isolates from CSF samples were Cryptococcus neoformans , coagulase-negative Staphylococcus, Acinetobacter baumannii , and Klebsiella pneumonia. Conclusion Using TLA and setting up three shifts shortened the TAT of our clinical microbiology laboratory, especially for CSF samples.
    Type of Medium: Online Resource
    ISSN: 2235-2988
    URL: Article
    DOI: 10.3389/fcimb.2021.765504
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2021
    detail.hit.zdb_id: 2619676-1
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 3
    Online Resource
    Online Resource
    Epidemiology, Clinical Characteristics, Risk Factors, and Outcomes of Candidemia in a Large Tertiary Teaching Hospital in Western China: A Retrospective 5-Year Study from 2016 to 2020
    MDPI AG ; 2022
    In:  Antibiotics Vol. 11, No. 6 ( 2022-06-09), p. 788-
    Details
    In: Antibiotics, MDPI AG, Vol. 11, No. 6 ( 2022-06-09), p. 788-
    Abstract: The aim of this study was to investigate the current status of candidemia and evaluate the clinical characteristics, risk factors and outcomes among different species. We conducted a retrospective study by univariate and multivariate analysis between Candida albicans and non-albicans Candida (NAC) species in a Chinese national medical center from 2016 to 2020. Among the 259 episodes, C. albicans (38.6%) was the leading species, followed by C. tropicalis (24.3%), C. parapsilosis (20.5%), and C. glabrata (12.4%). Most C. albicans and C. parapsilosis were susceptible to nine tested antifungal agents, whereas C. tropicalis showed 30.2~65.9% resistance/non-wild-type to four azoles with great cross-resistance, indicating that fluconazole should not be used for empirical antifungal treatment. In multivariable models, the factor related to an increased risk of NAC was glucocorticoid exposure, whereas gastrointestinal hemorrhage and thoracoabdominal drainage catheters were associated with an increased risk in C. albicans. Subgroup analysis revealed leukemia and lymphoma, as well as glucocorticoid exposure, to be factors independently associated with C. tropicalis in comparison with C. albicans candidemia. No significant differences in 7-day mortality or 30-day mortality were observed between C. albicans and NAC. This study may provide useful information with respect to choosing empirical antifungal agents and exploring differences in molecular mechanisms.
    Type of Medium: Online Resource
    ISSN: 2079-6382
    URL: Article
    DOI: 10.3390/antibiotics11060788
    Language: English
    Publisher: MDPI AG
    Publication Date: 2022
    detail.hit.zdb_id: 2681345-2
    SSG: 15,3
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 4
    Online Resource
    Online Resource
    PTX3 gene polymorphism associated with cryptococcosis in HIV‐uninfected Chinese patients
    Wiley ; 2021
    In:  Mycoses Vol. 64, No. 4 ( 2021-04), p. 405-411
    Details
    In: Mycoses, Wiley, Vol. 64, No. 4 ( 2021-04), p. 405-411
    Abstract: For Chinese Han populations, cryptococcosis are more likely to occur in HIV‐uninfected patients instead of HIV‐infected patients compared with other countries and regions, implying that there may be genetic predisposing factors for cryptococcosis in the Chinese Han populations. However, the retail mechanism has not been clarified. Objectives We aimed to conduct an association analysis between the single nucleotide polymorphisms (SNPs) of pattern recognition receptors (PRR) genes and the susceptibility to cryptococcosis in HIV‐uninfected Chinese patients, which may provide new genetic predisposing factors for early‐risk prediction of disease, individualised treatment and prognosis monitoring. Patients/methods Using the SNaPshot SNP typing technique, eight SNPs of PRR genes (Dectin‐2, Dectin‐1, PTX3, CXCL8, IL12B, IFIH1, TLR1 and CD209) were typed on 97 HIV‐uninfected cryptococcosis patients and 120 healthy controls who admitted to West China Hospital, Sichuan University, China, from 1 March 2018 to 30 December 2018. The results were analysed by the SHEsis software and SPSS 20.0 software. Results It was found that that PTX3 rs2305619 polymorphism was associated with cryptococcosis in HIV‐uninfected patients. Compared with the GG genotype, AA genotype increased the risk of cryptococcosis in HIV‐uninfected patients ( p  = .015, OR, 2.579; 95% CI, 1.202–5.535). In the immunocompetent patients, the AA genotype had a higher risk ( p  = .002, OR, 4.399; 95% CI, 1.745–11.088). Further verification found that the plasma PTX3 level of the AA genotype was significantly higher than the GA or GG genotype (60.28 ± 16.12 vs 7.32 ± 0.79, p   〈  .001). Conclusions PTX3 rs2305619 polymorphism was associated with cryptococcosis in HIV‐uninfected Chinese patients. The AA genotype increased the risk of cryptococcosis, and its plasma PTX3 level was significantly higher than that of GA or GG genotype.
    Type of Medium: Online Resource
    ISSN: 0933-7407 , 1439-0507
    URL: Issue
    URL: Article
    DOI: 10.1111/myc.v64.4
    DOI: 10.1111/myc.13228
    Language: English
    Publisher: Wiley
    Publication Date: 2021
    detail.hit.zdb_id: 2020780-3
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...