In:
The Laryngoscope, Wiley, Vol. 123, No. 11 ( 2013-11), p. 2770-2775
Abstract:
Conventional lasers ablate tissue through photothermal, photomechanical, and/or photoionizing effects, which may result in collateral tissue damage. The novel nonionizing picosecond infrared laser (PIRL) selectively energizes tissue water molecules using ultrafast pulses to drive ablation on timescales faster than energy transport to minimize collateral damage to adjacent cells. Study Design Animal cadaver study. Methods Cuts in porcine laryngeal epithelium, lamina propria, and cartilage were made using PIRL and carbon dioxide (CO 2 ) laser. Lateral damage zones and cutting gaps were histologically compared. Results The mean widths of epithelial (8.5 μm), subepithelial (10.9 μm), and cartilage damage zones (8.1 μm) were significantly lower for cuts made by PIRL compared with CO 2 laser (p 〈 0.001). Mean cutting gaps in vocal fold (174.7 μm) and epiglottic cartilage (56.3 μm) were significantly narrower for cuts made by PIRL compared with CO 2 laser ( P 〈 0.01, P 〈 0.05). Conclusion PIRL ablation demonstrates superiority over CO 2 laser in cutting precision with less collateral tissue damage. Level of Evidence N/A. Laryngoscope , 123:2770–2775, 2013
Type of Medium:
Online Resource
ISSN:
0023-852X
,
1531-4995
DOI:
10.1002/lary.v123.11
Language:
English
Publisher:
Wiley
Publication Date:
2013
detail.hit.zdb_id:
2026089-1
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