In:
Asia-Pacific Psychiatry, Wiley, Vol. 8, No. 4 ( 2016-12), p. 302-305
Kurzfassung:
The aim of this study was to compare hair thyroid hormone ( TH ) levels among first‐episode patients with major depressive disorder ( F ‐ MDD ), recurrent patients with major depressive disorder ( R ‐ MDD ) and healthy controls ( HC ). Methods The Hamilton Depression Scale ( HAMD ) and Hamilton Anxiety Scale ( HAMA ) were used to evaluate the clinical symptoms of patients. Electrochemiluminescence immunoassay was used to measure the hair TH levels. We compared the differences in hair TH levels among F ‐ MDD patients, R‐ MDD patients, and HC . Results Before the disease episode, hair T 3 levels differed significantly between F ‐ MDD patients and HC . In the disease episode, hair T 3 levels differed significantly between F ‐ MDD or R ‐ MDD patients and HC ; and hair T 4 levels differed significantly between R ‐ MDD patients and HC . Hair T 3 levels significantly negative correlated with HAMD scores in F ‐ MDD patients. Conclusions Our findings suggested that disease duration of recurring episodes of depression may influence hair TH levels.
Materialart:
Online-Ressource
ISSN:
1758-5864
,
1758-5872
DOI:
10.1111/appy.2016.8.issue-4
Sprache:
Englisch
Verlag:
Wiley
Publikationsdatum:
2016
ZDB Id:
2506343-1
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